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Age of Information Based User Scheduling and Data Assignment in Multi-User Mobile Edge Computing Networks:An Online Algorithm

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China Communications 2024年第5期21卷 153-165页

作者： Ge yiyang Xiong Ke dong Rui Lu Yang Fan Pingyi Qu Gang School of Computer and Information Technology Beijing Jiaotong UniversityBeijing 100044China Engineering Research Center of Network Management Technology for High Speed Railway of Ministry of Education Beijing 100044China Beijing Engineering Research Center of High-speed Railway Broadband Mobile Communications Beijing 100044China Department of Electronic Engineering Tsinghua UniversityBeijing 100084China Beijing National Research Center for Information Science and Technology Tsinghua UniversityBeijing 100084China Department of Electrical and Computer Engineering College ParkMarylandUSA

This paper investigates the age of information(AoI)-based multi-user mobile edge computing(MEC)network with partial offloading mode.The weighted sum AoI(WSA)is first analyzed and derived,and then a WSA minimization problem is formulated by jointly optimizing the user scheduling and data assignment.Due to the non-analytic expression of the WSA w.***.t.the optimization variables and the unknowability of future network information,the problem cannot be solved with known solution methods.Therefore,an online Joint Partial Offloading and User Scheduling Optimization(JPOUSO)algorithm is proposed by transforming the original problem into a single-slot data assignment subproblem and a single-slot user scheduling sub-problem and solving the two sub-problems separately.We analyze the computational complexity of the presented JPO-USO algorithm,which is of O(N),with N being the number of users.Simulation results show that the proposed JPO-USO algorithm is able to achieve better AoI performance compared with various baseline methods.It is shown that both the user’s data assignment and the user’s AoI should be jointly taken into account to decrease the system WSA when scheduling users.

关键词： age of information(aoi) mobile edge computing(mec) user scheduling

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The protective effect of icariin on glucocorticoid-damaged BMECs explored by microfluidic organ chip

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Chinese Chemical Letters 2022年第6期33卷 3177-3182页

作者： Tengqi Li Qingyu Zhang Fuqiang Gao Yadi Liu Wei Sun yiyang dong Department of Orthopedics Peking University China-Japan Friendship School of Clinical MedicineBeijing 100029China Department of Orthopedics Peking University Shougang HospitalBeijing 100144China Department of Orthopedics Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJi’nan 250021China Department of Orthopedics China-Japan Friendship HospitalBeijing 100029China Office of Academic Affairs Beijing University of Chemical TechnologyBeijing 100029China Department of Pharmaceutical Analysis College of Life Science and TechnologyBeijing University of Chemical TechnologyBeijing 100029China

Osteonecrosis of the femoral head(ONFH)is a devastating musculoskeletal disease characterized by the impaired circulation of bone.The purpose of this study was to explore the underlying mechanisms of the protective effect of icariin on the glucocorticoid-induced injury of bone microvascular endothelial cells(BMECs).Normal BMECs were extracted from the femoral heads by enzymatic isolation and magneticactivated cell sorting methods.Dexamethasone and icariin were used to intervene BMECs in microfluidic organ chips,and phalloidin staining was conducted to observe the cell morphology and viability.Then next-generation transcriptome sequencing and real-time quantitative reverse transcription-polymerase chain reaction(q RT-PCR)were performed to identify the differentially expressed genes(DEGs)in different groups.Through the microfluidic organ chip,it can be observed that after dexamethasone intervention,the filamentous structure in cell fibers disappeared and the cell morphology changed from spindle to round until death.Icariin could relieve these changes and showed a protective effect on glucocorticoiddamaged BMECs.In addition,201 DEGs were detected between the icariin protection group and the dexamethasone group,which were significantly enriched in 17 signaling pathways.8 of the top ten selected hub genes(IL6,PTGS2,VEGFA,etc.)were confirmed by q RT-PCR.Transcription factors(TFs)-gene network showed 63 connections between 18 TFs and 12 DEGs.For instance,GATA2 could regulate 5 DEGs.The associations between 92 mi RNA and 12 DEGs were visualized in a mi RNA-gene network.The hub mi RNA,has-mir-335–5 p was predicted to interact with 8 DEGs(PTGS2,VEGFA,etc.).Microfluidic organ chips could provide excellent morphological results for cell experiments,by which it could be observed that icariin showed a protective effect on the glucocorticoid-induced injury of BMECs.Beside,these DEGs,possible regulatory TF(GATA2,FOXC1,etc.)and mi RNA(has-mir-335–5 p)might be dysregulated in the initiation of ONFH and have prospective importance

关键词： Osteonecrosis of the femoral head Bone microvascular endothelial cells Glucocorticoid Microfluidic chip Bioinformatic analysis

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Aptasensor Based on Screen-Printed Carbon Electrodes Modified with CS/AuNPs for Sensitive Detection of Okadaic Acid in Shellfish

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Journal of Analysis and Testing 2023年第2期7卷 128-135页

作者： Ni Zeng Xinyi Wang yiyang dong Yan Yang Yingai Yin Lianhui Zhao Xu Wang College of Life Science and Technology Beijing University of Chemical TechnologyBeijing 100029China

Okadaic acid(OA),a small molecule substance derived from shellfish,is one of the most widely distributed marine toxins with acute symptoms of vomiting and diarrhea after accidental ingestion.For this,there is an urgently need for sensitive and reliable methods to detect OA in real shellfish samples.In this study,a simple aptasensor based on screen-printed carbon electrode(SPCE)with modification of chitosan(CS)and gold nanoparticles(Au NPs)was designed for electrochemical determination of OA,and the electrode surface was modified with Au NPs by potential-sweeping electrodeposition,which greatly improved the electrochemical response.The entire detection and characterization process were carried out by cyclic voltammetry(CV)with a linear correlation in the range of 0.01-100 ng/m L and a limit of detection(LOD)of 6.7 pg/m L.Furthermore,recovery rates of 92.3-116%were obtained demonstrating excellent accuracy through the recovery trial of mussel and scallop samples.

关键词： Okadaic acid Aptasensor Screen-printed carbon electrode Chitosan Gold nanoparticles Cyclic voltammetry

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From lab to market:a review of commercialization and advances for binders in lithium-,zinc-,sodium-ion batteries

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Nano Research Energy 2024年第1期3卷 152-171页

作者： Chang Su Xuan Gao Kejiang Liu Yuhang Dai Haobo dong yiyang Liu Jiayan Zhu Qiuxia Zhang Hongzhen He Guanjie He Department of Management Technologyand EconomicsETH ZürichZürich 8092Switzerland Christopher Ingold Laboratory Department of ChemistryUniversity College LondonLondon WC1H0AJUK Electrochemical Innovation Lab Department of Chemical EngineeringUniversity College LondonLondon WC1E7JEUK Department of Physics Hong Kong Baptist UniversityHong Kong 999077China State Key Lab of Superhard Materials College of PhysicsJilin UniversityChangchun 130012China

The paper discusses the progress and commercialization of binders for energy storage applications,such as batteries.It explains the role of binders in holding together active materials and current collectors,and highlights the challenges associated with conventional organic solvents in binders.The potential of aqueous binders is introduced as a cost-effective and environmentally friendly alternative.The advantages and limitations of different types of binders are discussed,and the importance of binder selection for optimal battery performance is emphasized.The current state of commercialization of binders is reviewed,and the need for collaboration between researchers,manufacturers,and policymakers to develop and promote environmentally friendly and cost-effective binders is emphasized.The paper concludes by outlining future directions for research and development to further improve the performance and commercialization of binders,while addressing limitations such as lack of standardization,high cost,and long-term stability and reliability.

关键词： battery commercialization binder energy storage

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State of the art:Lateral flow assay(LFA) biosensor for on-site rapid detection

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Chinese Chemical Letters 2018年第11期29卷 1567-1577页

作者： Shuai Zhao Sai Wang Shan Zhang Jiahui Liu yiyang dong College of Life Science and Technology Beijing University of Chemical Technology College of Food Science and Engineering Ocean University of China

Recently, lateral flow assay （LFA） has attracted researchers＇ attention because of its considerable advantages of superior portability, rapid detection, cost-effectiveness and ease of use. This review provides a brief overview of latest researches of LFA, including the practical use of LFA in both qualitative and quantitative analysis in different areas. Though bio-recognition molecules in the LFA used to be antibodies, a new kind of recognition element called aptamer, showing significant advantages, is developed rapidly in recent years. The highly specific recognition of aptamers/antibodies and targets are combined with the excellent properties of a dry-reagent strip biosensor that enables efficiently detection in point-of-care applications. Herein, we compared the aptamers with antibodies, summarized the principle of LFAs, and three main elements for the LFAs （recognition molecule, signal transduction element, the targets）. Additionally, we summarized different optimal experimental conditions in the recent LFA-related studies to give detailed overview of the LFA development. We hope the review can give a general guide for the development of LFAs.

关键词： Lateral flow assay Aptamer Antibodies Recognition Signal transduction

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Spatiotemporal Variability of Surface Wind Speed during 1961-2017 in the Jing-Jin-Ji Region,China

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Journal of Meteorological Research 2020年第3期34卷 621-632页

作者： Weijie DIAO Yong ZHAO yiyang dong Jiaqi ZHAI Qingming WANG Yunpeng GUI State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower Research(IWHR)Beijing 100038 Department of Hydraulic Engineering Tsinghua UniversityBeijing 100084

Wind speed variations are influenced by both natural climate and human activities.It is important to understand the spatial and temporal distributions of wind speed and to analyze the cause of its changes.In this study,data from 26 meteorological stations in the Jing-Jin-Ji region of North China from 1961 to 2017 are analyzed by using the Mann-Kendall(MK)test.Over the study period,wind speed first decreased by−0.028 m s^-1 yr^-1(p<0.01)in 1961^-1991,and then increased by 0.002 m s^-1 yr^-1(p<0.05)in 1992-2017.Wind speed was the highest in spring(2.98 m s^-1),followed by winter,summer,and autumn.The largest wind speed changes for 1961-1991 and 1992-2017 occurred in winter(−0.0392 and 0.0065 m s^-1 yr^-1,respectively);these values represented 36%and 58%of the annual wind speed changes.More than 90.4%of the wind speed was concentrated in the range of 1-5 m s^-1,according to the variation in the number of days with wind speed of different grades.Specifically,the decrease in wind speed in 1961^-1991 was due to the decrease in days with wind speed of 3-5 m s^-1,while the increase in wind speed in 1992-2017 was mainly due to the increase in days with wind speed of 2-4 m s^-1.In terms of driving factors,variations in wind speed were closely correlated with temperature and atmospheric pressure,whereas elevation and underlying surface also influenced these changes.

关键词： climate change Jing–Jin–Ji region Mann–Kendall(MK)trend test wind speed driving factors

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A cytoprotective graphene oxide-polyelectrolytes nanoshell for single-cell encapsulation

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Frontiers of Chemical Science and Engineering 2021年第2期15卷 410-420页

作者： Luanying He Yulin Chang Junhao Zhu Ying Bi Wenlin An yiyang dong Jia-Hui Liu Shihui Wang College of Life Science and Technology Beijing University of Chemical TechnologyBeijing 100029China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

Graphene oxide(GO)has been increasingly utilized in the fields of food,biomedicine,environment and other fields because of its benign biocompatible.We encapsulated two kinds of GO with different sizes on yeast cells with the assistance of polyelectrolytes poly(styrene sulfonic acid)sodium salt(PSS)and polyglutamic acid(PGA)(termed as Y@GO).The result does not show a significant difference between the properties of the two types of Y@GO(namely Y@GO1 and Y@GO2).The encapsulation layers are optimized as Yeast/PGA/PSS/PGA/GO/PGA/PSS based on the morphology,dispersity,colony-forming unit,and zeta potential.The encapsulation of GO increases the roughness of the yeast.It is proved that the Y@GO increases the survival time and enhance the activity of yeast cells.The GO shell improves the resistance of yeast cells against pH and salt stresses and extends the storage time of yeast cells.

关键词： GO yeast polyelectrolyte cytoprotection nanomaterials

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考虑生态耗水的干旱区绿洲灌溉用水效率评价指标与方法

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水资源保护 2024年第3期40卷 78-89页

作者：赵勇董义阳翟家齐刘宽刘志武梁犁丽中国水利水电科学研究院流域水循环模拟与调控国家重点实验室北京 100038 中国长江三峡集团有限公司科学技术研究院北京 101199 中国水利水电科学研究院流域水循环模拟与调控国家重点实验室北京 100038 天津大学水利工程仿真与安全国家重点实验室天津 300072

针对现行干旱区绿洲尺度灌溉用水效率评价对生态服务效益考虑不足的问题,提出了在绿洲尺度上考虑生态耗水的灌溉用水效率评价指标和方法,并应用于宁夏引黄灌溉绿洲.结果表明:宁夏引黄灌溉绿洲农田蒸散消耗水量中的灌溉水量平均占比达74.... 详细信息

针对现行干旱区绿洲尺度灌溉用水效率评价对生态服务效益考虑不足的问题,提出了在绿洲尺度上考虑生态耗水的灌溉用水效率评价指标和方法,并应用于宁夏引黄灌溉绿洲.结果表明:宁夏引黄灌溉绿洲农田蒸散消耗水量中的灌溉水量平均占比达74.7％,生态系统蒸散消耗水量中的灌溉水量平均占比达39.8％,灌溉水对生态系统的支撑作用显著;考虑生态耗水前后的灌溉用水效率差为0.052～0.074,占未考虑生态耗水灌溉用水效率的13.9％～16.1％,灌溉水的生态服务效益明显;提出的评价指标与方法合理可行,能客观反映干旱区灌溉用水的综合效益.

关键词：灌溉用水效率生态耗水干旱区蒸散发水循环模拟宁夏引黄灌溉绿洲

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东太平洋海隆海底热液蠕虫管道矿化特征及其成因

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地球科学 2024年第1期49卷 224-237页

作者：罗礼涛王叶剑蔡翌旸董传奇韩喜球成都理工大学沉积地质研究院四川成都610059 自然资源部海底科学重点实验室自然资源部第二海洋研究所浙江杭州310012 上海交通大学海洋学院上海200240

热液管状蠕虫生物矿化现象在海底热液喷口区发育广泛,但蠕虫管道矿化和风化氧化过程及其控制因素知之甚少.对采自东太平洋海隆热液蠕虫矿化管道样品开展了高分辨率矿物学和元素分布研究.结果表明,样品具有以胶状黄铁矿为主的多圈层矿化... 详细信息

热液管状蠕虫生物矿化现象在海底热液喷口区发育广泛,但蠕虫管道矿化和风化氧化过程及其控制因素知之甚少.对采自东太平洋海隆热液蠕虫矿化管道样品开展了高分辨率矿物学和元素分布研究.结果表明,样品具有以胶状黄铁矿为主的多圈层矿化结构,分为快速(F型)和慢速矿化(S型)两种类型.相比“S型”样品,“F型”的管壁更厚,同心层的数量少、间隙小、厚度均一.这主要受矿物沉淀速率的影响,即矿物的快速沉淀加快了蠕虫管道生长和矿化.此外,“F型”样品外壁分布的草莓状黄铁矿,表明纳-微米晶硫化物矿物的定向生长是形成胶状黄铁矿带的重要中间途径.而“S型”管壁从内到外具有氧化程度逐渐增加、胶状黄铁矿逐渐减薄的显著特征,指示样品同时受到了后期低温、富Fe-Si热液流体和低温海水风化氧化作用的影响.本项研究为理解现代海底热液系统的管状蠕虫矿化机制提供了新见解.

关键词：海底热液管状蠕虫矿物学管道圈层结构硫化物矿化风化氧化

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下肢外骨骼机器人联合踝关节康复训练对脑卒中后步行功能障碍患者步行功能的影响

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中华物理医学与康复杂志 2024年第2期46卷 118-122页

作者：董延广王强张文娟肖懿洋张永祥青岛大学附属医院康复医学科青岛266000 青岛妇女儿童医院青岛266034

目的:观察下肢外骨骼机器人联合踝关节康复训练对脑卒中后步行功能障碍患者步行功能的影响。方法:将脑卒中患者45例按随机数字表法分为对照组、机器人组和联合组,每组患者15例。对照组采用常规康复训练,机器人组在常规康复训练的基础上... 详细信息

目的:观察下肢外骨骼机器人联合踝关节康复训练对脑卒中后步行功能障碍患者步行功能的影响。方法:将脑卒中患者45例按随机数字表法分为对照组、机器人组和联合组,每组患者15例。对照组采用常规康复训练,机器人组在常规康复训练的基础上增加下肢外骨骼机器人辅助的步行训练;联合组每日常规康复训练20 min,然后每日增加下肢外骨骼机器人辅助的步行训练10 min,和踝关节康复训练10 min。3组患者均每日训练1次,每周训练5 d,连续训练3周。治疗前和治疗3周后(治疗后)采用Fugl-Meyer运动功能量表评定下肢部分(FMA-LE)、Holden功能性步行分级(FAC)、步速和步频来评价3组患者的步行功能。结果:治疗后,3组患者的FMA-LE评分、FAC分级、步速和步频均较组内治疗前均显著改善,差异均有统计学意义( P<0.05)。治疗后,机器人组的FMA-LE评分、步速和步频均显著优于对照组治疗后( P<0.05),而联合组治疗后的FMA-LE评分、步速和步频分别为(22.67±1.63)分、(0.65±0.05)m/s和(80.80±4.28)步/min,均显著优于对照组和机器人组治疗后,差异均有统计学意义( P<0.05)。结论:下肢外骨骼机器人联合踝关节康复训练可显著改善脑卒中后步行功能障碍患者的步行功能。

关键词：脑卒中下肢外骨骼机器人踝关节康复训练

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