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Spatial Optimization and Reconstruction of Old Communities under the Background of Aging

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Journal of Landscape Research 2024年第2期16卷 51-53,60页

作者： LI yiwen LI Daoyong HE Qilin School of Architecture and Art North China University of TechnologyBeijing 100144China Planning and Comprehensive Affairs Center of Beijing Economic and Technological Development Zone Beijing 100176China

As aging becomes increasingly serious,how to make the life of the elderly more convenient and comfortable has become one of the social problems to be solved *** residential areas are one of spaces where the elderly *** this paper,the prominent problems in the community space of existing old residential areas that are not conducive to the life of the elderly were analyzed,and corresponding countermeasures to transform the community space were put *** is hoped that public space can play its due value and make old residential areas glow with new vitality.

关键词： Aging adaptability Community public space Elderly care community Space transformation

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注意缺陷多动障碍共病智力障碍的诊治挑战

《民法典》第1223条(缺陷医疗产品及不合格血液致害责任)评注

中国儿童保健杂志 2024年第06期32卷 581-585页

作者：章依文国家儿童医学中心上海交通大学医学院附属上海儿童医学中心发育行为儿科

注意缺陷多动障碍(ADHD)是儿童中常见的神经发育障碍，也是智力障碍(ID/DD)人群中最常见的共病之一。共病患者的症状复杂，且功能损害严重，导致诊断困难和治疗效果不佳。对于ADHD共病ID的治疗，需要综合非药物和药物治疗。总体来说，... 详细信息

注意缺陷多动障碍(ADHD)是儿童中常见的神经发育障碍，也是智力障碍(ID/DD)人群中最常见的共病之一。共病患者的症状复杂，且功能损害严重，导致诊断困难和治疗效果不佳。对于ADHD共病ID的治疗，需要综合非药物和药物治疗。总体来说，跨专业的综合评估和治疗，结合长期随访和个性化管理，有助于提升共病患者的生活质量和功能。

关键词：注意缺陷多动障碍智力障碍共病诊治儿童

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法学家 2024年第1期 174-190,196页

作者：武亦文武汉大学法学院

缺陷医疗产品致害责任适用无过错责任归责原则,不合格血液致害责任不应同缺陷医疗产品致害责任相区分。在认定医疗产品是否存在缺陷、血液是否不合格时,应以不合理危险为基本衡量标准,以强制性标准为辅助性标准。本条虽没有明确销售者... 详细信息

缺陷医疗产品致害责任适用无过错责任归责原则,不合格血液致害责任不应同缺陷医疗产品致害责任相区分。在认定医疗产品是否存在缺陷、血液是否不合格时,应以不合理危险为基本衡量标准,以强制性标准为辅助性标准。本条虽没有明确销售者为责任主体,但按照产品责任的一般规定,销售者同样为缺陷医疗产品致害责任的责任主体。此外,根据《医疗器械监督管理条例》,医疗器械注册人、备案人也应为本条责任主体,在法律适用上应类推适用药品上市许可持有人的规定。缺陷医疗产品及不合格血液致害责任的外部责任形态为连带责任。当本条责任主体明知医疗产品存在缺陷仍使用医疗产品,导致患者死亡或健康严重损害时,仍存在适用惩罚性赔偿责任的空间。医疗机构、销售者、运输者或仓储者等对医疗产品缺陷或血液不合格的产生具有过错时,为最终责任主体;否则,最终责任主体为药品上市许可持有人、医疗器械注册人、备案人、缺陷医疗产品的生产者及血液提供机构。

关键词：缺陷医疗产品不合格血液医疗损害责任产品责任追偿权

Unveiling the secrets of diatom-mediated calcification:Implications for the biological pump

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Science China Earth Sciences 2024年第9期67卷 2895-2909页

作者： yiwen PAN Yifan LI Chen-Tung Arthur CHEN Zong-Pei JIANG Wei-Jun CAI Yunwen SHEN Zesheng DING Qixian CHEN Yanan DI Wei FAN Chenba ZHU Ying CHEN Ocean College Zhejiang UniversityZhoushan 316021China Hainan Institute of Zhejiang University Sanya 570203China Department of Oceanography Sun Yat-Sen UniversityGaoxiong 80424China School of Marine Science and Policy University of DelawareNewark DE 19716USA Carbon Neutral Innovation Research Center Xiamen UniversityXiamen 361005China

Siliceous diatoms are one of the most prominent actors in the oceans,and they account for approximately 40%of the primary production and particulate organic carbon export *** is believed that changes in carbon flux caused by variations in diatom distribution can lead to significant climate *** the fundamental pathways of diatom-driven carbon sequestration have long been established,there are no reports of CaCO_(3) precipitation induced by marine diatom *** manuscript introduces novel details regarding the enhancement of aragonite precipitation during photosynthesis in Skeletonema costatum in both artificial and natural *** direct measurements of cell surfaces via a pH microelectrode and zeta potential analyzer,it was determined that the diatom-mediated promotion of CaCO_(3) precipitation is achieved through the creation of specific microenvironments with concentrated[CO_(3)^(2-)]and[Ca^(2+)]and/or the dehydrating effect of adsorbed Ca^(2+).Based on this mechanism,it is highly plausible that diatom-mediated calcification could occur in the oceans,an assertion that was supported by the significant deviation of total alkalinity(TA)from the conservative TA-salinity mixing line during a Skeletonema costatum bloom in the East China Sea and other similar *** newly discovered calcification pathway establishes a link between particulate inorganic and organic carbon flux and thus helps in the reassessment of marine carbon export fluxes and CO_(2) sequestration *** discovery may have important ramifications for assessing marine carbon cycling and predicting the potential effects of future ocean acidification.

关键词： Diatom bloom Skeletonema costatum Calcification Biological carbon pump Counter carbonate pump

离婚时商业保险权益分割的法理逻辑与规范适用

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现代法学 2024年第2期46卷 179-192页

作者：武亦文武汉大学法学院武汉430072

离婚时商业保险权益的分割应当基于保险法和夫妻财产法相协同的视角,以保险法和夫妻财产法上的价值理念和规范原理为宏观指引,以财产保险和人身保险相区分为基本处理框架,以夫妻财产分割制度的原则、价值目标和一般规范为根本遵循,以保... 详细信息

离婚时商业保险权益的分割应当基于保险法和夫妻财产法相协同的视角,以保险法和夫妻财产法上的价值理念和规范原理为宏观指引,以财产保险和人身保险相区分为基本处理框架,以夫妻财产分割制度的原则、价值目标和一般规范为根本遵循,以保险法相关规则为具体分析工具。离婚时商业保险权益的分割包含积极财产的分割和潜在补偿的给付两部分内容。对于财产保险,其待分割权益主要为保险金,需结合保险标的归属和保费来源两项因素确定不同情形下的保险金分割与经济补偿规则。对于人身保险,其待分割权益主要包括保险金、退保现金价值、保单红利和投资收益,需区分保障型、储蓄型和投资型三种不同保险类型,并结合保险合同主体的不同构成、是否产生保险金、保费的不同来源、保险期间是否已完全经过等因素,确定不同情形下具体存在哪些保险权益可供分割、如何予以分割以及如何给付经济补偿。

关键词：离婚保险权益分割财产保险人身保险经济补偿

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Toosendanin: upgrade of an old agent in cancer treatment

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Chinese Journal of Natural Medicines 2024年第10期22卷 887-899页

作者： LI Shuwei XIONG Qingyi SHEN yiwen LIN Jiayi ZHANG Lijun WU Ye JIN Jinmei LUAN Xin Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology Institute of Interdisciplinary Integrative Medicine Research and Shuguang Hospital Shanghai University of Traditional Chinese Medicine

Toosendanin(TSN), a tetracyclic triterpenoid derived from Melia toosendan and M. azedarach, demonstrates broad application prospects in cancer treatment. Although previously employed as a pesticide, recent studies have revealed its potential therapeutic value in treating various types of cancer. TSN exerts an anticancer effect via mechanisms including proliferation inhibition, apoptosis induction, migration suppression, and angiogenesis inhibition. However, TSN's toxicity, particularly its hepatotoxicity, significantly limits its therapeutic application. This review explored the dual nature of TSN, evaluating both its anticancer potential and toxicological risks, emphasizing the importance of balancing these aspects in therapeutic applications. Furthermore, we investigated the incorporation of TSN into novel therapeutic strategies, such as Proteolysis-targeting chimeras(PROTAC) technology and nanotechnology-based drug delivery systems(DDS), which enhance treatment efficacy while mitigating toxicity in normal tissues.

关键词： Cancer therapy Hepatotoxicity Nano-delivery systems PROTAC Toosendanin

Selection of New Energy Development Models in Rural Jilin Province under Different Situations

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Proceedings of Business and Economic Studies 2024年第4期7卷 231-237页

作者： Lijuan Zhang Xuetao Tang yiwen Wang Yanwei Wang School of Economics and Management Northeast Electric Power UniversityJilin 132011Jilin ProvinceChina Jilin City No.1 Middle School Jilin 132000Jilin ProvinceChina

Jilin Province’s vast rural areas are endowed with abundant new energy resources,which provide a fundamental condition for the development of new energy in rural *** paper will explore the various possibilities of new energy development in rural Jilin under the background of grid infrastructure construction,the deepening of electricity market reform,the modernization of agriculture and rural areas,and the transformation of *** will draw conclusions on the reasonable development models of new energy in rural Jilin under different scenarios,providing a reference for the development of new energy in rural Jilin and rural revitalization.

关键词： Rural revitalization Rural areas New energy

Organocatalytic radical aminoacylation of alkenes forβ-aminoketone synthesis

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Science China Chemistry 2024年

作者： Ayisenbati Jialingbieke Xinying Hu Zuquan Liu Xiyun Lin yiwen Yin Jibin Li Yatian Huang Ding Du State Key Laboratory of Natural Medicines School of Science China Pharmaceutical University

An NHC organocatalytic radical aminoacylation of alkenes has been developed by using aldehydes as the acylating reagents and activated aryloxy-amides as the N-radical precursors, providing a new platform for modular access to highly functionalized β-aminoketones. The key to the success of this reaction relies on the single electron transfer(SET) event between the enolates of Breslow intermediates and carefully screened N-radical precursors, followed by a radical addition and radical-radical coupling relay process. The protocol features simple and readily available materials(abundant and feed-stock aldehydes and alkenes),mild reaction conditions(metal-, photo-and oxidant-free, in EA at room temperature), easily removable protecting group for late-stage functionalization.

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Tuning Excitation Transport in a Dissipative Rydberg Ring

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Chinese Physics Letters 2024年第3期41卷 37-43页

作者：韩奕文易为 CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Center For Excellence in Quantum Information and Quantum Physics Hefei 230026China

We demonstrate the flexible tunability of excitation transport in Rydberg atoms,under the interplay of controlled dissipation and interaction-induced synthetic *** a minimum four-site setup,i.e.,a triangular configura... 详细信息

关键词： excitation Rydberg triangular