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积极老龄化背景下我国“医养结合”养老模式分析

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老龄化研究 2024年第4期11卷 1541-1547页

作者：沈一雯南京林业大学马克思主义学院江苏南京

尊老敬老是中华民族的传统美德,爱老助老是全社会的共同责任。积极老龄化是近些年国家大力提倡的,随着我国人口老龄化进程的加快,各种养老模式应运而生,其中“医养结合”养老模式在应对我国人口老龄化问题上发挥重要作用。文章在积极老... 详细信息

尊老敬老是中华民族的传统美德,爱老助老是全社会的共同责任。积极老龄化是近些年国家大力提倡的,随着我国人口老龄化进程的加快,各种养老模式应运而生,其中“医养结合”养老模式在应对我国人口老龄化问题上发挥重要作用。文章在积极老龄化大背景下,首先对我国“医养结合”养老模式进行分析探讨,分析了当前“医养结合”养老模式面临的发展困境,包括医养结合供需矛盾突出,其中专业医养人才、资金及基础养老设施等方面供需存在不足,同时相关制度建设不健全,受传统养老观念影响等问题。然后寻求突破路径,针对性调节医养结合供需矛盾问题、制定医养结合指导性制度、打破传统养老观念,努力让亿万老年人体验更加完善的养老模式,享受晚年生活。

关键词：积极老龄化医养结合养老模式

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上海城区电力电缆通道规划相关问题研究

上海节能 2024年第7期 1153-1159页

作者：周越高佳运申意文国网上海市电力公司市北供电公司

近年来随着城市化建设架空线入地等工程逐步开展,城市电力可靠性要求更高,对电力电缆通道的需求量亦更高。然而,电力电缆通道的规划面临诸多实际难题,一方面与城市发展不匹配,与其他工程建设规划协调不足,另一方面在上海城区内又易受地... 详细信息

近年来随着城市化建设架空线入地等工程逐步开展,城市电力可靠性要求更高,对电力电缆通道的需求量亦更高。然而,电力电缆通道的规划面临诸多实际难题,一方面与城市发展不匹配,与其他工程建设规划协调不足,另一方面在上海城区内又易受地理环境影响导致通道拥堵难以规划落地。以上海城区部分路段为实际案例,详细阐述并分析电力电缆通道规划发展的实际问题,同时总结提出统一规划、安全运行、经济合理的总体原则以及差异化的区域原则,以期为未来电力通道规划提供有效参考,确保电网建设项目规划的科学性与合理性。

关键词：电力电缆通道规划实际问题原则

BCNU/PLGA microspheres:a promising strategy for the treatment of gliomas in mice

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Chinese Journal of Cancer Research 2014年第1期26卷 81-88页

作者： Tongming Zhu yiwen shen Qisheng Tang Luping Chen Huasong Gao Jianhong Zhu Fudan University Huashan Hospital Dept.of Neurosurgery National Key Laboratory for Medical NeurobiologyInstitutes of Brain ScienceShanghai Medical College-Fudan University

Objective：To investigate the effects of BCNU/PLGA microspheres on tumor growth,apoptosis and chemotherapy resistance in a C57BL/6 mice orthotopic brain glioma model using GL261 cell ***：BCNU/PLGA sustained-release microspheres were prepared by the water-in-oil-in-water emulsion ***261 cells were intracranially injected into C57BL/6 mouse by using the stereotactic technology.A total of 60 tumor-bearing mice were randomly and equally divided into three groups：untreated control,PLGA treated,BCNU/PLGA *** resonance imaging （MRI） was taken to evaluate tumor ***/PLGA sustained-release wafers were implanted in the treatment group two weeks after *** time and quality were *** were harvested,and immunohistochemical staining was used to check the expression of Bax,Bcl-2,and O6-methylguanine-DNA methyltransferase （MGMT）.Statistical methods was used for analysis of relevant ***：BCNU/PLGA sustained-release wafers were fabricated and implanted *** is statistical difference of survival time between the BCNU/PLGA treated group and control groups （P＜0.05）.MRIscan showed inhibitory effect of BCNU/PLGA on tumor *** to the group A and B,BCNU/PLGA decreased the expression of apoptosis related gene Bcl-2 （P＜0.05）,but did not elevate the expression level of Bax （P＞0.05）,with the ratio of Bax/Bcl-2 *** MGMT protein expression,no statistically significant change was found in treated group （P＞0.05）.Conclusions：Local implantation of BCNU/PLGA microspheres improved the survival quality and time of GL261 glioma-bearing mice significandy,inhibited the tumor proliferation,induced more cell apoptosis,and did not increase the chemotherapy resistance.

关键词： BCNU/PLGA microspheres glioma interstitial chemotherapy apoptosis

Current status of cell-mediated regenerative therapies for human spinal cord injury

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Neuroscience Bulletin 2014年第4期30卷 671-682页

作者： Tongming Zhu Qisheng Tang Huasong Gao yiwen shen Luping Chen Jianhong Zhu Department of Neurosurgery Fudan University Huashan Hospital National Key Laboratory of Medical Neurobiology Institutes of Brain ScienceShanghai Medical CollegeFudan University

During the past decade, significant advances have been made in refinements for regenerative therapies following human spinal cord injury （SCI）. Positive results have been achieved with different types of cells in various clinical studies of SCI. In this review, we summarize recently-completed clinical trials using cell- mediated regenerative therapies for human SCI, together with ongoing trials using neural stem cells. Specifically, clinical studies published in Chinese journals are included. These studies show that current transplantation therapies are relatively safe, and have provided varying degrees of neurological recovery. However, many obstacles exist, hindering the introduction of a specific clinical therapy, including complications and their causes, selection of the target population, and optimization of transplantation material. Despite these and other challenges, with the collaboration of research groups and strong support from various organizations, cell-mediated regenerative therapies will open new perspectives for SCI treatment.

关键词： cell-mediated regenerative therapy spinal cord injury clinical trials stem cell

复合夹板治疗移位型桡骨远端骨折的效果和医护配合研究

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创伤外科杂志 2024年第3期26卷 192-197页

作者：施玲玲沈奕雯殷渠东李鑫魏长宝无锡市第九人民医院骨科江苏无锡214062

目的探讨复合夹板治疗移位型桡骨远端骨折的效果和医护配合。方法回顾性分析2020年8月—2022年9月无锡市第九人民医院骨科采用自主设计的复合夹板固定移位型桡骨远端骨折患者25例,男性11例,女性14例;年龄32~79岁,平均56.9岁。护士配合... 详细信息

目的探讨复合夹板治疗移位型桡骨远端骨折的效果和医护配合。方法回顾性分析2020年8月—2022年9月无锡市第九人民医院骨科采用自主设计的复合夹板固定移位型桡骨远端骨折患者25例,男性11例,女性14例;年龄32~79岁,平均56.9岁。护士配合医师实施骨折复位和复合夹板固定,以及牵引期间密切观察和指导患者学会如何正确使用牵引装置并观察治疗效果。采用Lidstr9m影像学分级评价骨折移位,采用Cooney评分和患者自行评估量表(PRWE)分别评价腕关节功能恢复。结果固定后1周肿胀评分(2.1±0.5)分。6例(24%)发生骨折再移位,与牵引带和夹板发生松弛未得到及时、正确处置有关。其中2例再次整复达Lidstr9m满意标准,1例未整复者继续夹板固定,另3例未达满意标准者改为手术治疗(手术率12%)。随访6~12个月,平均8.1个月。骨折均愈合,临床愈合时间5~8周,平均5.9周,无局部皮肤压疮和神经压迫症状。末次随访,桡骨高度(9.0±1.3)mm,掌倾角(8.0±3.1)°,尺偏角(22.3±2.2)°,掌屈度(41.4±11.0)°,背伸度(36.1±8.9)°,桡侧倾斜度(23.1±10.0)°,尺侧倾斜度(27.0±5.2)°,旋前(70.4±7.5)°,旋后(71.5±9.6)°,手握力达对侧(77.7±6.0)%,VAS(0.6±0.6)分,Cooney评分(87.9±8.6)分,腕关节功能优良率88%,PRWE评分(18.7±3.1)分。结论复合夹板固定移位型桡骨远端骨折的短缩移位率和手术率较低,使用安全;保持牵引带适当张力和指导患者学会正确使用牵引装置的护理工作,对治疗效果起重要作用。

关键词：桡骨远端骨折非手术治疗复合夹板纵向牵引力疗效

Microwave-assisted continuous flow phytosynthesis of silver nanoparticle/reduced graphene oxide composites and related visible light catalytic performance

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Journal of Environmental Sciences 2022年第5期34卷 286-293页

作者： Houyu Wang Chun-Gang Yuan Chenchen Liu Xuelei Duan Qi Guo yiwen shen Jingfu Liu Yongsheng Chen Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control Department of Environmental Science&EngineeringNorth China Electric Power UniversityBaoding 071000China Wetland Research Center for Baiyangdian Lake North China Electric Power UniversityBaoding 071000China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China School of Civil and Environmental Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

The creation of an environmentally friendly synthesis method for silver nanomaterials(Ag-NPs)is an urgent concern for sustainable nanotechnology *** the present study,a novel straightforward and green method for the preparation of silver nanoparti-cle/reduced graphene oxide(AgNP/rGO)composites was successfully developed through the combination of phytosynthesis,continuous flow synthesis and *** persimmon(Diospyros kaki Thunb.)extracts were used as both plant reducing and capping agents for fast online synthesis of AgNP/rGO *** experimental param-eters were optimized and the morphologies of the prepared materials were *** characterization results reveal that spherical AgNPs were quickly synthesized and uni-formly dispersed on rGO sheets using the proposed online *** transform in-frared spectroscopy analysis confirmed that phenols,flavonoids,and other substances in the plant extracts played a decisive role in the synthesis of AgNP/rGO *** sodium borohydride(NaBH4)degradation of p-nitrophenol(4-NP)as a model,the catalytic activity of the prepared AgNP/rGO materials was *** complete degradation of 4-NP was achieved within 12 min through the use of AgNP/rGO materials,and the compos-ite had a much better catalytic activity than the bare AgNPs and rGO *** with the conventional chemical method,our online method is facile,fast,cost-efficient,and en-vironmentally friendly.

关键词： Microwave Continuous flow Phytosynthesis Silver nanocomposite Catalysis

Distribution Characteristics and Health Risk Assessment of Antimony in Atmospheric Particulates in a Northern City of China

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Chemical Research in Chinese Universities 2023年第3期39卷 465-471页

作者： shen yiwen ZHAO Hao ZHAO Changxian DONG Shuofei CAO Yuanming XIE Jiaojao LYU Meiling YUAN Chungang Hebei Key Lab of Power-plant Flue Gas Multi-pollutants Control Department of Environmental Science&EngineeringNorth China Electric Power UniversityBaoding071000P.R.China Key Laboratory of Resources and Environmental Systems Optimization Ministry of EducationCollege of Environmental Science and EngineeringNorth China Electric Power UniversityBeijing102206P.R.China Agilent Technologies Co. Ltd.(China)Beijing100102P.R.China

Over the last several decades,scientists have established a wealth of evidence to demonstrate the risks posed to human health by toxic elements in atmospheric particulate matter(PM).Antimony(Sb),as one of ever ignored PM-bound heavy metals,attracts more and more attentions and has been regarded as one emerging air pollutant with the change of pollution sources of particulate *** study the distribution of Sb in PM with different particle sizes is of great practical significance for understanding its source and health *** this study,the size distributions of Sb in PM(PM_(2.5),PM_(10)and TSP)in different seasons were studied from July 2018 to May *** high concentration of PM-bound Sb was found and the health risk was *** was enriched in fine particles and showed higher values in winter,which was probably caused by coal combustion and meteorological *** was also found that traffic-related non-exhaust emissions might become another main contribution to fine particle *** risk assessment demonstrated that the hazard quotient(HQ)of Sb in PM_(2.5)and PM_(10)for children(PM_(2.5):1.54,PM_(10):1.32)exceeded the acceptable threshold and ingestion contributed the most to the HQ for both children and adults.

关键词： Particulate matter(PM) Antimony Size distribution Health risk

All-natural phyllosilicate-polysaccharide triboelectric sensor for machine learning-assisted human motion prediction

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npj Flexible Electronics 2023年第1期7卷 351-360页

作者： Yuanhao Liu yiwen shen Wei Ding Xiangkun Zhang Weiliang Tian Song Yang Bin Hui Kewei Zhang Key Laboratory of Chemical Engineering in South Xinjiang College of Chemistry and Chemical EngineeringTarim University843300 AlarP.R.China State Key Laboratory of Bio-Fibers and Eco-Textiles Collaborative Innovation Center for Marine Biomass FibersMaterials and Textiles of Shandong ProvinceCollege of Materials Science and EngineeringInstitute of Marine Biobased MaterialsQingdao University266071 QingdaoP.R.China Department of Hepatology Beijing Ditan Hospital of Capital Medical University100015 BeijingP.R.China

The rapid development of smart and carbon-neutral cities motivates the potential of natural materials for triboelectric ***,the relatively deficient charge density makes it challenging to achieve high Maxwell’s displacement ***,we propose a methodology for improving the triboelectricity of marine polysaccharide by incorporating charged phyllosilicate *** a proof-of-concept,a flexible,flame-retardant,and eco-friendly triboelectric sensor is developed based on all-natural composite paper from alginate fibers and vermiculite *** interlaced fibers and nanosheets not only enable superior electrical output but also give rise to wear resistance and mechanical *** fabricated triboelectric sensor successfully monitors slight motion signals from various joints of human ***,an effective machine-learning model is developed for human motion identification and prediction with accuracy of 96.2%and 99.8%,*** work offers a promising strategy for improving the triboelectricity of organo-substrates and enables implementation of self-powered and intelligent platform for emerging applications.

关键词： prediction motion enable

Mutations of Desmoglein‑2 in Sudden Unexplained Death in the Chinese Han Population

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Journal of Forensic Science and Medicine 2019年第2期5卷 61-64页

作者： Junyi Lin Yulei Yang Ziqin Zhao yiwen shen Kaijun Ma Mingchang Zhang Department of Forensic Medicine School of Basic Medical SciencesFudan UniversityShanghaiChina2Shangha Key

Sudden unexplained death(SUD)remains a puzzle in forensic ***‑2(DSG2)has been linked to arrhythmogenic right ventricular cardiomyopathy which may cause life‑threatening ventricular arrhythmias and sudden *** arrhythmias resulting in sudden death also occur in the absence of morphologic cardiac abnormalities at *** hypothesized that DSG2 mutations may be responsible for certain Chinese SUD *** sequenced all 15 exons of DSG2 in DNA extracted from postmortem heart tissues of 25 Chinese patients dying from *** primers were designed using the Primer Express 3.0 *** sequencing for both sense and antisense strands was performed with a BigDye Terminator DNA sequencing kit on a 3130 Xl Genetic *** damage prediction was made using Mutation Taster,PolyPhen,and SIFT *** 2 of 25 cases of Chinese SUD samples,two DSG2 heterozygous mutations(p.P927 L and p.T1070M)were identified,and one is probably *** concluded that DSG2 mutations may be related to the occurrence of part of SUD cases in the Chinese Han population.

关键词： Desmoglein‑2 desmosomal mutation sudden cardiac death sudden unexplained death