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A probe into the acid deposition mitigation path in China over the last four decades and beyond

National Science Review 2024年第4期11卷 84-92页

作者： Qian Yu Xiaodong Ge Haotian Zheng Jia Xing Lei Duan Dongwei Lv Dian Ding Zhaoxin Dong yisheng sun Posch Maximilian Danni Xie Yu Zhao Bin Zhao Shuxiao Wang Jan Mulder Thorj?rn Larssen Jiming Hao State Key Laboratory of Environmental Simulation and Pollution Control School of EnvironmentTsinghua University State Key Laboratory of Pollution Control &Resource Reuse and School of the Environment Nanjing University State Environmental Protection Key Laboratory of Sources and Control of Air Pollution Complex School of EnvironmentTsinghua University International Institute for Applied System Analysis(IIASA) School of Land Engineering Chang'an University Faculty of Environmental Sciences and Natural Resource Management Norwegian University of Life Sciences Norwegian Institute for Water Research

China currently has the highest acid deposition globally, yet research on its status, impacts, causes and controls is lacking. Here, we compiled data and calculated critical loads regarding acid deposition. The results showed that the abatement measures in China have achieved a sharp decline in the emissions of acidifying pollutants and a continuous recovery of precipitation p H, despite the drastic growth in the economy and energy consumption. However, the risk of ecological acidification and eutrophication showed no significant decrease. With similar emission reductions, the decline in areas at risk of acidification in China(7.0%) lags behind those in Europe(20%) or the USA(15%). This was because, unlike Europe and the USA, China's abatement strategies primarily target air quality improvement rather than mitigating ecological impacts. Given that the area with the risk of eutrophication induced by nitrogen deposition remained at 13%of the country even under the scenario of achieving the dual targets of air quality and carbon dioxide mitigation in 2035, we explored an enhanced ammonia abatement pathway. With a further 27% reduction in ammonia by 2035, China could largely eliminate the impacts of acid deposition. This research serves as a valuable reference for China's future acid deposition control and for other nations facing similar challenges.

关键词： acid deposition critical loads acidification eutrophication ammonia abatement

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新型冠状病毒感染合并横纹肌溶解症1例

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皮肤科学通报 2024年第2期41卷 214-216页

作者：裴志超朱函坪孙一晟姚苹苹徐芳沈鑫浙江省疾病预防控制中心微生物所浙江杭州310051 宿迁市第一人民医院医学检验科江苏宿迁223800

患者男,30岁,长期进行高强度训练运动,新型冠状病毒感染后出现全身肌肉酸痛、乏力等症状持续半月余,体力不能支撑体育运动。3个月后患者自觉身体恢复开始进行适应性训练,1周后出现胸闷、肌肉剧烈疼痛、乏力、尿液呈茶色等症状。入院查体... 详细信息

患者男,30岁,长期进行高强度训练运动,新型冠状病毒感染后出现全身肌肉酸痛、乏力等症状持续半月余,体力不能支撑体育运动。3个月后患者自觉身体恢复开始进行适应性训练,1周后出现胸闷、肌肉剧烈疼痛、乏力、尿液呈茶色等症状。入院查体:双上肢肌肉压痛,四肢活动正常,未见明显水肿;实验室检查:血浆中肌酸激酶31 007 U/L,血清肌酸激酶同工酶153 U/L,肌红蛋白2170 ng/mL。诊断:横纹肌溶解症。经过补液、碱化尿液等治疗后,患者肝肾功能、心肌酶谱各项指标均下降至正常范围内,遂出院。

关键词：新型冠状病毒横纹肌溶解症肌酸激酶

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我如何学习做小说

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上海文化 2023年第7期 50-58页

作者：孙一圣不详

1.阅读从一开始,我便深受先锋文学的影响。余华莫言马原格非苏童等等,能找到的都会去看,再后来外国文学的阅读谱系也是从先锋文学那里拉出来,那一长串的名字,诸如卡夫卡、马尔克斯、博尔赫斯、福克纳、鲁尔福等等。因此,我最初的写作也... 详细信息

1.阅读从一开始,我便深受先锋文学的影响。余华莫言马原格非苏童等等,能找到的都会去看,再后来外国文学的阅读谱系也是从先锋文学那里拉出来,那一长串的名字,诸如卡夫卡、马尔克斯、博尔赫斯、福克纳、鲁尔福等等。因此,我最初的写作也都似是而非,肆意发展,很多情节也都没有道理可讲。比如,卡夫卡有一篇很短的小说,简直就是一句话,名字叫《树》,让我们第一次看一下这篇小说.

关键词：先锋文学卡夫卡博尔赫斯马尔克斯外国文学鲁尔福格非苏童

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Impacts of Nutlin-3a and exercise on murine double minute 2-enriched glioma treatment

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Neural Regeneration Research 2025年第4期20卷 1135-1152页

作者： yisheng Chen Zhongcheng Fan Zhiwen Luo Xueran Kang Renwen Wan Fangqi Li Weiwei Lin Zhihua Han Beijie Qi Jinrong Lin Yaying sun Jiebin Huang Yuzhen Xu Shiyi Chen Department of Sport Medicine Huashan HospitalFudan UniversityShanghaiChina Department of Orthopedic Surgery Hainan Province Clinical Medical CenterHaikou Affiliated Hospital of Central South University Xiangya School of MedicineHaikouHainan ProvinceChina Department of Basic Medicine Shanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Neurosurgery Second Affiliated Hospital of Zhejiang University School of MedicineZhejiang UniversityHangzhouZhejiang ProvinceChina Department of Orthopedics Shanghai General HospitalSchool of Medicine Shanghai Jiao Tong UniversityShanghaiChina Department of Infectious Diseases Children’s Hospital of Fudan UniversityNational Children’s Medical CenterShanghaiChina Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina

Recent research has demonstrated the impact of physical activity on the prognosis of glioma patients,with evidence suggesting exercise may reduce mortality risks and aid neural *** role of the small ubiquitin-like modifier(SUMO)protein,especially post-exercise,in cancer progression,is gaining attention,as are the potential anti-cancer effects of *** used machine learning to create the exercise and SUMO-related gene signature(ESLRS).This signature shows how physical activity might help improve the outlook for low-grade glioma and other *** demonstrated the prognostic and immunotherapeutic significance of ESLRS markers,specifically highlighting how murine double minute 2(MDM2),a component of the ESLRS,can be targeted by *** underscores the intricate relationship between natural compounds such as nutlin-3 and immune *** comprehensive CRISPR screening,we validated the effects of specific ESLRS genes on low-grade glioma *** also revealed insights into the effectiveness of Nutlin-3a as a potent MDM2 inhibitor through molecular docking and dynamic ***-3a inhibited glioma cell proliferation and activated the p53 *** efficacy decreased with MDM2 overexpression,and this was reversed by Nutlin-3a or *** using a low-grade glioma mouse model highlighted the effect of physical activity on oxidative stress and molecular pathway ***,both physical exercise and Nutlin-3a administration improved physical function in mice bearing tumors derived from MDM2-overexpressing *** results suggest the potential for Nutlin-3a,an MDM2 inhibitor,with physical exercise as a therapeutic approach for glioma *** research also supports the use of natural products for therapy and sheds light on the interaction of exercise,natural products,and immune regulation in cancer treatment.

关键词： exercise and SUMO-related gene signatures(ESLRS) glioblastoma management low-grade glioma natural bioactives neural regeneration physical exercise

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Evidence for distortion-induced local electric polarization in α-RuCl3

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Science China(Physics,Mechanics & Astronomy) 2024年第9期Mechanics & Astronomy) .卷 169-177页

作者： Xinrun Mi De Hou Xiao Wang Sabreen Hammouda Caixing Liu Zijian Xiong Han Li Yan Liu Guiwen Wang Aifeng Wang yisheng Chai Yang Qi Wei Li Xiaoyuan Zhou Yixi Su D.I.Khomskii Mingquan He Zhigao Sheng Young sun College of Physics Center of Quantum Materials and DevicesChongqing University Anhui Key Laboratory of Condensed Matter Physics at Extreme Conditions High Magnetic Field LaboratoryHefei Institutes of Physical ScienceAnhuiChinese Academy of Sciences University of Science and Technology of China Jülich Centre for Neutron Scienceat Heinz Maier-Leibnitz Zentrum(JCNS-MLZ) Forschungszentrum Jülich GmbH School of Physics Beihang University Analytical and Testing Center Chongqing University State Key Laboratory of Surface Physics Department of PhysicsFudan University CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of Sciences Ⅱ.Physikalisches Institut Universit?t zu K?ln

The spin-orbit assisted Mott insulator α-RuCl3is a prime candidate for material realization of the Kitaev quantum spin *** little attention has been paid to charge degrees of freedom, charge effects, such as electric polarization, may arise in this system. Here, we report distortion-induced local electric polarization in α-RuCl3as evidenced by single-crystal X-ray diffraction,second harmonic generation（SHG） and dielectric measurements. The SHG signal appears at room temperature and develops substantially in the Kitaev paramagnetic state when short-range spin correlations come into play. Despite sizable pyroelectric currents in the Kitaev paramagnetic state, the absence of hysteresis in the polarization-electric field（P-E） points to the shortrange nature of electric polarization. This localized electric polarization is likely the result of distortion-induced charge dimerization, achieved through virtual hopping-induced charge redistribution. In addition, the electric polarization is boosted by short-range spin correlations via spin-phonon coupling in the Kitaev paramagnetic state. Our results emphasize the importance of charge degrees of freedom in α-RuCl3, which establish a novel platform to investigate charge effects in Kitaev materials.

关键词： Mott insulator Kitaev quantum spin liquid electric polarization

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Evidence for distortion-induced local electric polarization in α-RuCl

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Science China(Physics,Mechanics & Astronomy) 2024年

作者： Xinrun Mi De Hou Xiao Wang Sabreen Hammouda Caixing Liu Zijian Xiong Han Li Yan Liu Guiwen Wang Aifeng Wang yisheng Chai Yang Qi Wei Li Xiaoyuan Zhou Yixi Su D.I.Khomskii Mingquan He Zhigao Sheng Young sun College of Physics Center of Quantum Materials and Devices Chongqing University Anhui Key Laboratory of Condensed Matter Physics at Extreme Conditions High Magnetic Field Laboratory Hefei Institutes of Physical Science Anhui Chinese Academy of Sciences University of Science and Technology of China Jülich Centre for Neutron Scienceat Heinz Maier-Leibnitz Zentrum (JCNS-MLZ) Forschungszentrum Jülich GmbH School of Physics Beihang University Analytical and Testing Center Chongqing University State Key Laboratory of Surface Physics Department of Physics Fudan University CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences II.Physikalisches Institut Universit?t zu K?ln

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Isolation and Growth Characteristics of SARS-CoV-2 in Vero Cell

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Virologica Sinica 2020年第3期35卷 348-350页

作者： Pingping Yao Yachun Zhang yisheng sun Yulin Gu Fang Xu Bo Su Chen Chen Hangjing Lu Dehui Wang Zhangnv Yang Biao Niu Jiancai Chen Lixia Xie Lei Chen Yajing Zhang Hui Wang Yuying Zhao Yue Guo Juncheng Ruan Zhiyong Zhu Zhenfang Fu Dayong Tian Qi An Jianmin Jiang Hanping Zhu Key Lab of Vaccine Prevention and Control of Infectious Disease of Zhejiang ProvinceZhejiang Provincial Center for Disease Control and PreventionHangzhou 310051China R&D Department Shanghai King-Cell Biotechnology Co.Ltd.Shanghai 201506China State Key Laboratory of Agricultural Microbiology Huazhong Agricultural UniversityWuhan 430070China College of Veterinary Medicine Huazhong Agricultural UniversityWuhan 430070China

Dear Editors,The coronavirus disease 2019(COVID-19),caused by SARS-CoV-2,broke out in early December 2019 has escalated into a global pandemic(Lai et al.2020).Till the May 20 th 2020,more than 4,700,000 people were in... 详细信息

关键词： al. infected Cell

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超临界二氧化碳介质中晶圆清洗与选择性刻蚀研究进展

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化工学报 2024年第1期75卷 110-119页

作者：张泽欣郑伟中徐益升胡冬冬卓欣宇宗原孙伟振赵玲华东理工大学化学工程联合国家重点实验室上海200237

随着集成电路特征尺寸的逐渐减小,器件结构会要求更高的纵横比,常规湿法清洗由于表面张力很难进入晶圆深沟槽结构内部,不能满足更细线条工艺要求和高深宽比结构,直接影响沟槽内的污染物去除效果;常规湿法刻蚀各向异性差、结构坍塌严重... 详细信息

随着集成电路特征尺寸的逐渐减小,器件结构会要求更高的纵横比,常规湿法清洗由于表面张力很难进入晶圆深沟槽结构内部,不能满足更细线条工艺要求和高深宽比结构,直接影响沟槽内的污染物去除效果;常规湿法刻蚀各向异性差、结构坍塌严重、深沟槽刻蚀效果不明显;而等离子体干法刻蚀则存在刻蚀速率慢、光刻胶脱落和黏附、结构损伤、废气处理等一系列问题。超临界清洗和刻蚀技术是最具有前景的环境友好、无损伤技术,能够耦合刻蚀、清洗与干燥工艺为一体,且可以循环使用,安全环保,是晶圆制造过程中常规清洗和刻蚀的首选替代技术。综述了超临界二氧化碳中晶圆清洗与选择性刻蚀的研究进展,重点介绍了超临界二氧化碳共溶剂、微乳液体系在光刻胶剥离以及含硅基底选择性蚀刻中的应用,展望了超临界二氧化碳晶圆清洗和刻蚀存在的问题和发展趋势。

关键词：晶圆清洗晶圆刻蚀超临界二氧化碳超临界流体微乳液

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