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Long-term change in low-cloud cover in Southeast China during cold seasons

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Atmospheric and Oceanic Science Letters 2022年第6期15卷 9-14页

作者： Zhe Chen Minghuai Wang Haipeng Zhang Shuheng Lin Zhun Guo yiquan jiang Chen Zhou Institute for Climate and Global Change Research School of Atmospheric SciencesNanjing UniversityNanjingChina Department of Atmospheric and Oceanic Science&Earth System Science Interdisciplinary Center University of MarylandCollege ParkMDUSA School of Atmospheric Sciences Sun Yat-sen UniversityZhuhaiChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina

Southeast China has comparable stratus cloud to that over the oceans,especially in the cold seasons(winter and spring),and this cloud has a substantial impact on energy and hydrological ***,uncertainties remain across datasets and simulation results about the long-term trend in low-cloud cover in Southeast China,making it difficult to understand climate change and related physical *** this study,multiple datasets and numerical simulations were applied to show that low-cloud cover in Southeast China has gone through two stages since 1980—specifically,a decline and then a rise,with the turning point around *** regional moisture transport plays a crucial role in low-cloud cover changes in the cold seasons and is mainly affected by the Hadley Cell in winter and the Walker Circulation in spring,*** moisture transport was not well simulated in CMIP6 climate models,leading to poor simulation of the low-cloud cover trend in these *** study provides insights into further understanding the regional climate changes in Southeast China.

关键词： Low-cloud cover Large-scale circulation Hadley cell Pacific walker circulation

A New View of the Dynamics of Particle Structure

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A New View of the Dynamics of Particle Structure

LncRNA RP11-307C12.11 promotes the growth of hepatocellular carcinoma by acting as a molecular sponge of miR-138

作者： yiquan jiang Huikequan Data Technology Co. Ltd.

关键词： Nuclear Energy Nuclear Fusion Material Structure Logic Emptiness Centrifugal Motion Centripetal Force Distribution of Motion and Force and Space Human Sensory Limit

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Liver Research 2019年第3期3卷 240-249页

作者： Yinan Deng Yusheng Cheng Kaining Zeng Haibo Li Yiming Huang yiquan jiang Tingting Xia Tong Zhang Yang Yang Department of Hepatic Surgery and Liver Transplantation Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Liver Disease Research GuangzhouChina Center for Reproductive Medicine The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina

Background:Abnormal expression of long non-coding RNAs(lncRNAs)has been found in almost all tumors in humans,providing numerous potential diagnostic and prognostic biomarkers,and therapeutic *** and methods:The Cancer Genome Atlas(TCGA)database was used to screen potential LncRNAs,and 30 paired hepatocellular carcinoma(HCC)tissues were used to investigate RP11-307C12.11 expression levels by qRT-PCR and another 105 HCC tissues by in situ hybridizsation(ISH).RP11-307C12.11 overexpression and knockdown experiments were performed to investigate the effects of RP11-307C12.11 on HCC growth through in vitro and in vivo assays(MTT assay,colony formation assay,EdU assay,and xenograft model).The molecular mechanism underlying these effects was confirmed by MS2-RIP-assay,RIP assay,luciferase assay,and rescue ***:RP11-307C12.11 expression level was significantly higher in tumor tissues than in the adjacent normal *** RP11-307C12.11 expression level was associated with poor prognosis of HCC patients,and it may be represented as an independent prognostic biomarker in patients with ***,RP11-307C12.11 overexpression promoted HCC growth both in vitro and in vivo;however,its knockdown reversed these ***,we found that RP11-307C12.11 expressed predominantly in the cytoplasm and sponged microRNA(miR)-138 to regulate its common target CCND1 and ***:Thus,we found that RP11-307C12.11 acts as an oncogene in HCC by binding to miR-138,which might provide a novel target for HCC therapy.

关键词： Long non-coding RNAs(lncRNAs) LncRNA RP11-307C12.11 Hepatocellular carcinoma(HCC) Growth MicroRNA(MiR)-138

综合医院后勤物业服务外包管理问题分析及对策研究——以上海市同济医院管理实践为例

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中国医院建筑与装备 2023年第1期24卷 57-59页

作者：蒋义权上海市同济医院上海200000

结合上海市同济医院的后勤管理实践,以问卷调研的形式剖析院内物业服务外包管理现状及存在的问题,并提出针对性的管理对策,旨在提高后勤物业服务质量和工作效率。

关键词：综合医院后勤物业服务外包

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医院后勤一站式服务中心建设必要性研究

中国医院建筑与装备 2022年第1期23卷 57-59页

作者：蒋义权上海市同济医院上海200065

分析了医院后勤管理的现状及存在的问题,从需求端出发,通过问卷调查的方式,分析了医院后勤一站式服务中心建设的必要性。通过建立后勤一站式服务中心,将后勤各部门服务整合并优化,最终形成一体化后勤保障管理体系,提供优质、便捷的后勤... 详细信息

分析了医院后勤管理的现状及存在的问题,从需求端出发,通过问卷调查的方式,分析了医院后勤一站式服务中心建设的必要性。通过建立后勤一站式服务中心,将后勤各部门服务整合并优化,最终形成一体化后勤保障管理体系,提供优质、便捷的后勤服务。

关键词：后勤一站式服务中心流程改造满意度医院后勤管理

Newcastle disease virus suppresses antigen presentation via inhibiting IL-12 expression in dendritic cells

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第3期25卷 254-270页

作者： Fulong NAN Wenlong NAN Xin YAN Hui WANG Shasha jiang Shuyun ZHANG Zhongjie YU Xianjuan ZHANG Fengjun LIU Jun LI Xiaoqiong ZHOU Delei NIU yiquan LI Wei WANG Ning SHI Ningyi JIN Changzhan XIE Xiaoni CUI He ZHANG Bin WANG Huijun LU Department of Special Medicine Department of Pathogenic BiologySchool of Basic MedicineQingdao UniversityQingdao 266071China China Animal Health and Epidemiology Center Qingdao 266032China Academician Workstation of Jilin Province Changchun University of Chinese MedicineChangchun 130117China Institute of Virology Wenzhou UniversityWenzhou 325035China College of Veterinary Medicine Jilin UniversityChangchun 130012China Changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchun 130122China Sino-Cell Biomed Co. Ltd.Qingdao 266000China

As a potential vectored vaccine,Newcastle disease virus(NDV)has been subject to various studies for vaccine development,while relatively little research has outlined the immunomodulatory effect of the virus in antigen *** elucidate the key inhibitory factor in regulating the interaction of infected dendritic cells(DCs)and T cells,DCs were pretreated with the NDV vaccine strain LaSota as an inhibitor and stimulated with lipopolysaccharide(LPS)for further detection by enzyme-linked immunosorbent assay(ELISA),flow cytometry,immunoblotting,and quantitative real-time polymerase chain reaction(qRT-PCR).The results revealed that NDV infection resulted in the inhibition of interleukin(IL)-12p40 in DCs through a p38 mitogen-activated protein kinase(MAPK)-dependent manner,thus inhibiting the synthesis of IL-12p70,leading to the reduction in T cell proliferation and the secretion of interferon-(IFN-),tumor necrosis factor-α(TNF-α),and IL-6 induced by ***,downregulated cytokines accelerated the infection and viral transmission from DCs to T ***,several other strains of NDV also exhibited inhibitory *** current study reveals that NDV can modulate the intensity of the innate-adaptive immune cell crosstalk critically toward viral invasion improvement,highlighting a novel mechanism of virus-induced immunosuppression and providing new perspectives on the improvement of NDV-vectored vaccine.

关键词： Newcastle disease virus Dendritic cells Interleukin-12(IL-12) T cells Immunosuppression

风电场内风电机组连锁脱网机理与低电压穿越能力研究

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电力自动化设备 2013年第12期33卷 91-97页

作者：向昌明范立新蒋一泉顾天畏顾伟江苏方天电力技术有限公司江苏南京211102 东南大学电气工程学院江苏南京210096

在江苏地区各风电场相关参数及低电压穿越能力测试数据的基础上,在DIgSILENT中对基于双馈风电机组的大规模风电场进行建模,可详细描述风电场内各风机低电压穿越的动态特性。在不同的电压跌落场景下,对风电场内部各风电机组的不同故障反... 详细信息

在江苏地区各风电场相关参数及低电压穿越能力测试数据的基础上,在DIgSILENT中对基于双馈风电机组的大规模风电场进行建模,可详细描述风电场内各风机低电压穿越的动态特性。在不同的电压跌落场景下,对风电场内部各风电机组的不同故障反应特性进行比较分析,确定整个风电场的低电压穿越能力并得出规律性结论。通过严重故障仿真得到风电场内部风机的脱网时序分布,分析了风机之间交互影响机理与连锁脱网的详细过程。最后,提出适当提高撬棒保护整定值、网侧变换器灵活运行和采用SVC等装置进行动态无功补偿可以提高风电场低电压穿越能力。

关键词：风电场建模双馈机组低电压穿越撬棒保护 DIgSILENT

CAM3.0模式中黑碳及硫酸盐气溶胶浓度变化对东亚春季气候的影响研究

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气象科学 2011年第4期31卷 466-474页

作者：胡海波刘超张媛蒋益荃南京大学大气科学学院灾害性天气气候研究所南京210093 南京信息工程大学大气科学学院南京210093

本文采用CAM3.0模式研究东亚地区各种气溶胶浓度增加后对于东亚春季各气候要素,尤其是对降水和春季风场的影响。在模式中通过分别对区域(20～50°N,100～150°E)内黑碳气溶胶浓度单独加倍、硫酸盐气溶胶浓度单独加倍、两种气溶胶浓度同... 详细信息

本文采用CAM3.0模式研究东亚地区各种气溶胶浓度增加后对于东亚春季各气候要素,尤其是对降水和春季风场的影响。在模式中通过分别对区域(20～50°N,100～150°E)内黑碳气溶胶浓度单独加倍、硫酸盐气溶胶浓度单独加倍、两种气溶胶浓度同时加倍的实验方法,探讨不同气溶胶浓度变化在东亚春季气候变化中的具体作用。结果表明:在春季,3种气溶胶浓度增加方式都使得东亚地区表现出降水中南部减少北部增加,低层大气西南风异常以及地面温度南部增加北部减少。通过对110～120°E的断面分析发现,硫酸盐与黑碳气溶胶在春季首先影响约800 hPa以上大气的温度并通过不同的动力机制影响东亚地区的风场,风场的改变进而导致了云量和降水在东亚北方地区增多而中南部地区减少,并最终使得地面温度表现出东亚中南部地区增温而北方地区相对降温的特征。

关键词：黑碳气溶胶硫酸盐气溶胶降水减少

兰花茎腐病拮抗菌HJ-5的筛选和生防潜力评估

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河南农业科学 2021年第8期50卷 85-93页

作者：吕昂王成汤亚芳王立华姜益泉湖北工程学院生命科学技术学院/特色果蔬质量安全控制湖北省重点实验室湖北孝感432000

为给兰花茎腐病的绿色防控提供新的微生物资源,从湖北省孝感市健康的兰花幼苗根围土壤中分离筛选拮抗菌,并评估其生防潜力。结果表明,分离到8株对尖孢镰刀菌(Fusarium oxysporum)生长具有良好抑制作用的拮抗菌。16S rDNA测序比对和系统... 详细信息

为给兰花茎腐病的绿色防控提供新的微生物资源,从湖北省孝感市健康的兰花幼苗根围土壤中分离筛选拮抗菌,并评估其生防潜力。结果表明,分离到8株对尖孢镰刀菌(Fusarium oxysporum)生长具有良好抑制作用的拮抗菌。16S rDNA测序比对和系统发育树构建表明,这8株拮抗菌均为芽孢杆菌属(Bacillus)。其中,巨大芽孢杆菌(***)HJ-5在平板对峙中对尖孢镰刀菌具有较好且稳定的拮抗作用,将其无菌发酵液以5%添加到PDA培养基制成的带毒平板,可抑制灰葡萄孢菌(Botrytis cinerea)、炭疽菌(Colletotrichum siamense)、镰刀菌(***,***)、桃褐腐菌(Monilia fructigena)、毛霉菌(Mucor hiemails)、根霉菌(Rhizopus stolonifer)、核盘菌(Sclerotinia sclerotiorum)和白绢菌(Sclerotium rolfsii)的菌丝生长,抑菌率均高于50%。HJ-5无菌发酵液在高温、强酸碱和长时间紫外线照射条件下仍能保持一定的抗真菌活性。此外,在HJ-5的基因组中扩增到了抗菌物质表面活性素、丰原素的生物合成关键基因sfp和fenB。上述结果表明,巨大芽孢杆菌HJ-5对兰花茎腐病具有良好的生防潜力。

关键词：巨大芽孢杆菌拮抗作用兰花茎腐病无菌发酵液生防潜力