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中医药管理杂志 2024年第1期32卷 6-8页

作者：汪红孙艺琦俞冰秦路平仇凤梅浙江中医药大学浙江杭州311403

为了提升中医药院校药学专业学生学习生药学的兴趣,发挥其主观能动性,达到教学目标,对生药学实验课程教学内容、形式、考核方式等进行了改革,建立了涵盖课程内容体系,点面结合、传统与现代相结合的新的实验课程体系,改革效果良好,可以... 详细信息

为了提升中医药院校药学专业学生学习生药学的兴趣,发挥其主观能动性,达到教学目标,对生药学实验课程教学内容、形式、考核方式等进行了改革,建立了涵盖课程内容体系,点面结合、传统与现代相结合的新的实验课程体系,改革效果良好,可以推广使用。

关键词：中医药院校生药学实验教学改革

Advanced synaptic devices and their applications in biomimetic sensory neural system

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Chip 2023年第1期2卷 1-22页

作者： yiqi sun Jiean Li Sheng Li Yongchang Jiang Enze Wan Jiahan Zhang Yi Shi Lijia Pan School of Electronic Science and Engineering Nanjing University210093NanjingChina School of Microelectronics and Control Engineering Changzhou University213164ChangzhouChina School of Computer Sci-ence and Engineering Macao University of Science and Technology

Human nervous system,which is composed of neuron and synapse networks,is capable of processing information in a plastic,dataparallel,fault-tolerant,and energy-efficient *** by the ingenious working mechanism of this miraculous biological data processing system,scientists have been devoting great efforts to ar-tificial neural systems based on synaptic devices in recent *** continuous development of bioinspired sensors and synaptic devices in recent years have made it possible that artificial sensory neural systems are capable of capturing and processing stimuli informa-tion in real *** progress of biomimetic sensory neural systems could provide new methods for next-generation humanoid robotics,human-machine interfaces,and other frontier ***,this review summarized the recent progress of synaptic devices and biomimetic sensory neural ***,the opportunities and remaining challenges in the further development of biomimetic sensory neural systems were also outlined.

关键词： Artificial synapse Biomimetic sensory neural system Memristor Synaptic transistor

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煤矿采空区破损煤岩层的渗透性研究

中国矿山工程 2024年第4期53卷 32-37页

作者：宋喜东王恩志刘晓丽虎晓龙金慧高峻姚文理郭万平孙一奇国家能源集团宁夏煤业有限责任公司灵新煤矿宁夏灵武751410 清华大学水圈科学与水利工程全国重点实验室北京100084 国网山西省电力公司山西太原030000

利用矿井资源修建地下储库有助于实现“碳达峰,碳中和”战略目标,保障国家能源安全。掌握矿井储存空间内煤岩层渗透特性,是确定地下储库储存容量,保障储能系统稳定性和安全性的前提。本文以灵新煤矿矿井浓盐水地下储库工程为背景,开展... 详细信息

利用矿井资源修建地下储库有助于实现“碳达峰,碳中和”战略目标,保障国家能源安全。掌握矿井储存空间内煤岩层渗透特性,是确定地下储库储存容量,保障储能系统稳定性和安全性的前提。本文以灵新煤矿矿井浓盐水地下储库工程为背景,开展现场原位压水试验,对采掘完成的矿区煤岩层渗透特性进行研究,探明了矿区遗留煤柱、采区顶、低板的渗透特性和透水能力。试验结果表明各煤层遗留煤柱的稳定流量值为1.0~6.12 L/min,15和16煤顶板稳定流量为1.76~8.82 L/min,16煤的底板稳定渗流量为1.971~8.82 L/min。在此基础上,计算了各层煤柱透水率为0.046~0.261 Lu,顶板透水率为0.07~0.162 Lu,底板透水率为0.042,其中16煤煤柱透水率最大,为0.261 Lu。煤岩层透水性较差,有利于修建地下储库工程。

关键词：煤矿采空区破损岩体地下储库压水试验

基于粒子滤波与改进GVF Snake的人手跟踪算法

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上海交通大学学报 2018年第7期52卷 801-807页

作者：孙一奇吴爱国董娜邵一哲天津大学电气自动化与信息工程学院天津300072

为实现在复杂背景下对人手进行准确、快速的位置跟踪与轮廓跟踪,并针对粒子滤波无法获取人手目标的准确信息与人手深凹区域获取难的问题,提出一种基于肤色自适应梯度矢量流主动轮廓(Gradient Vector Flow Snake,GVF Snake)模型的粒子滤... 详细信息

为实现在复杂背景下对人手进行准确、快速的位置跟踪与轮廓跟踪,并针对粒子滤波无法获取人手目标的准确信息与人手深凹区域获取难的问题,提出一种基于肤色自适应梯度矢量流主动轮廓(Gradient Vector Flow Snake,GVF Snake)模型的粒子滤波算法实现人手跟踪.该算法首先对粒子滤波得到的人手区域进行肤色灰度增强,弱化背景梯度信息,然后对该区域利用引入自适应梯度矢量流场和肤色自适应外部引导力的GVF Snake模型,获取人手的真实轮廓以及准确的系统观测和系统状态,减少了粒子退化的可能,完成了更加准确的位置跟踪.实验表明:在复杂、运动背景甚至大范围遮挡的情况下,该改进算法获得了更加准确的人手轮廓,同时对人手跟踪的实时性提升了13%,均方根误差降低了48%.

关键词：人手跟踪人手轮廓梯度矢量流主动轮廓模型自适应粒子滤波

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“农超对接”过程中的订单违约问题研究

科研管理 2019年第6期40卷 225-233页

作者：杨浩雄孙祎琪马家骥北京工商大学商学院北京100048 首都流通业研究基地北京100048

在'农超对接'过程中,时常会出现订单违约问题。文章根据对宁夏回族自治区'农超对接'发展情况的调研结果,建立'农超对接'订单违约问题的多智能体仿真模型,揭示'农超对接'过程中订单违约问题的影响因素并回访验证。研究结果表明:(1)农户... 详细信息

在'农超对接'过程中,时常会出现订单违约问题。文章根据对宁夏回族自治区'农超对接'发展情况的调研结果,建立'农超对接'订单违约问题的多智能体仿真模型,揭示'农超对接'过程中订单违约问题的影响因素并回访验证。研究结果表明:(1)农户违约率与农产品价格增长百分比呈同向变化。(2)合作社和超市违约率与农产品合格率呈反向变化。(3)合作社通过向农户进行信息传递对其产生正向的引导作用。基于群体偏好理论,个体农户会受到周围其他农户的群体偏好影响做出选择(加入或退出合作社)。(4)初始阶段,政府政策扶持可以提高'农超对接'履约率。长期来看,提高农户科技水平更加能促进'农超对接'的发展,且其效果优于政府扶持。

关键词： “农超对接” 订单违约农产品供应链

集成双极晶体管基区表面电流的准二维模型及其参数的提取

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西安电子科技大学学报 1988年第4期 54-60页

作者：庄奕琪孙青西北电讯工程学院微电子研究所

考虑到少子准费米能级沿基区表面的非均匀分布,建立了集成双极晶体管基区表面电流的准二维模型。利用栅控晶体管作为测试结构,提取出了主要的基区表面参数。

关键词：双极晶体管表面复合模型基区表面电流

Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium

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Genes & Diseases 2024年第5期11卷 335-349页

作者： Jinxuan Zheng Rongcheng Yu yiqi Tang Sihui Su Sainan Wang Chenxi Liao Xuecong Li Jiabin Liao Dongsheng Yu Tingting Ai Wei Zhao Vicky Yau Chufeng Liu Liping Wu Yang Cao Hospital of Stomatology Guanghua School of StomatologyGuangdong Provincial Key Laboratory of StomatologySun Yat-sen UniversityGuangzhouGuangdong 510055China Guangdong Provincial Key Laboratory of Oral Diseases GuangzhouGuangdong 510055China Department of Cariology and Endodontology Peking University School and Hospital of Stomatology&National Center for Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Research Center of Oral Biomaterials and Digital Medical DevicesBeijing 100081China Department of Oral and Maxillofacial Surgery University at BuffaloBuffaloNY 14214USA Department of Orthodontics Stomatological HospitalSouthern Medical UniversityGuangzhouGuangdong 510280China

Developmental defects of enamel are common due to genetic and environmental factors before and after ***42,a Rho family small GTPase,regulates prenatal tooth development in ***,its role in postnatal tooth development,especially enamel formation,remains ***,we investigated Cdc42 functions in mouse enamel development and tooth repair after ***42 showed highly dynamic temporospatial patterns in the developing incisors,with robust expression in ameloblast and odontoblast ***,epithelium-specific Cdc42 deletion resulted in enamel defects in *** differentiation was inhibited,and hypomineralization of enamel was observed upon epithelial Cdc42 *** analysis showed that abnormal mitochondrial components,phosphotransferase activity,and ion channel regulator activity occurred in the Cdc42 mutant dental *** oxygen species accumulation was detected in the mutant mice,suggesting that abnormal oxidative stress occurred after Cdc42 ***,Cdc42 mutant mice showed delayed tooth repair and generated less calcified *** dysfunction and abnormal oxygen consumption were evidenced by reduced Apool and Timm8a1 expression,increased Atp5j2 levels,and reactive oxygen species overproduction in the mutant repair ***-specific Cdc42 deletion attenuated ERK1/2 signaling in the labial cervical *** Sox2 expression in the mutant labial cervical loop after clipping might lead to delayed tooth *** findings suggested that mitochondrial dysfunction,up-regulated oxidative stress,and abnormal ion channel activity may be among multiple factors responsible for the observed enamel defects in Cdc42 mutant ***,Cdc42 exerts multidimensional and pivotal roles in enamel development and is particularly required for ameloblast differentiation and enamel matrix formation.

关键词： Cdc42 Enamel defects Mitochondrial dysfunction Rho GTPase Tooth repair

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不同种类豆科植物中纤维素酶含量测定

辽宁中医药大学学报 2014年第10期16卷 63-65页

作者：孙艺琦郭晏华辽宁中医药大学药学院辽宁大连116600

目的:测定不同种类大豆中纤维素酶的含量。方法:采用DNS测还原糖法对大豆中的所含纤维素酶进行间接测定。结果:不同种类豆科植物中纤维素酶含量由高到低顺序为:黑豆>黄豆>红豆>绿豆。结论:此实验方法简便可靠,易于操作,通过对不同种类... 详细信息

目的:测定不同种类大豆中纤维素酶的含量。方法:采用DNS测还原糖法对大豆中的所含纤维素酶进行间接测定。结果:不同种类豆科植物中纤维素酶含量由高到低顺序为:黑豆>黄豆>红豆>绿豆。结论:此实验方法简便可靠,易于操作,通过对不同种类豆科植物中纤维素酶的含量比较,可为虎杖药材炮制辅料的筛选提供一定依据。不同种类豆科植物中所含纤维素酶含量不同,其中黑豆中所含的纤维素酶含量较多。

关键词：豆科植物纤维素酶含量测定

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电子器件可靠性的噪声表征方法

微电子技术 2000年第2期28卷 38-45页

作者：庄奕琪孙青西安电子科技大学微电子所西安710071

随着电子器件朝着高性能、小尺寸和长寿命方向发展 ,传统的寿命试验可靠性评价方法的局限性日益显著。近年来得到的大量研究结果表明 ,对于大多数电子器件 ,噪声是导致器件失效的各种潜在缺陷的敏感反映 ,噪声检测方法以其灵敏、普适、... 详细信息

随着电子器件朝着高性能、小尺寸和长寿命方向发展 ,传统的寿命试验可靠性评价方法的局限性日益显著。近年来得到的大量研究结果表明 ,对于大多数电子器件 ,噪声是导致器件失效的各种潜在缺陷的敏感反映 ,噪声检测方法以其灵敏、普适、快速和非破坏性的突出优点 ,正在发展成为一种新型的电子器件可靠性表征工具。本文对该领域目前的研究进展做了概括性的评述。

关键词：电子器件噪声可靠性

Uncertainty analysis of CO_2 flux components in subtropical evergreen coniferous plantation

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Science China Earth Sciences 2009年第2期52卷 257-268页

作者： LIU Min1,2,3, HE HongLin1, YU GuiRui1, LUO yiqi4, sun XiaoMin1 & WANG HuiMin1 1 Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China 2 Gradute School of the Chinese Academy of Sciences, Beijing 100049, China 3 School of Geography Science, Nanjing Normal University, Nanjing 210097, China 4 Department of Botany and Microbiology, University of Oklahoma, 770 Van Vleet Oval, Norman, OK 73019, USA Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing China Gradute School of the Chinese Academy of Sciences Beijing China School of Geography Science Nanjing Normal University Nanjing China Department of Botany and Microbiology University of Oklahoma Norman USA

We present an uncertainty analysis of ecological process parameters and CO2 flux components (Reco, NEE and gross ecosystem exchange (GEE)) derived from 3 years’ continuous eddy covariance meas-urements of CO2 fluxes at subtropical evergreen coniferous plantation, Qianyanzhou of ChinaFlux. Daily-differencing approach was used to analyze the random error of CO2 fluxes measurements and bootstrapping method was used to quantify the uncertainties of three CO2 flux components. In addition, we evaluated different models and optimization methods in influencing estimation of key parameters and CO2 flux components. The results show that: (1) Random flux error more closely follows a dou-ble-exponential (Laplace), rather than a normal (Gaussian) distribution. (2) Different optimization meth-ods result in different estimates of model parameters. Uncertainties of parameters estimated by the maximum likelihood estimation (MLE) are lower than those derived from ordinary least square method (OLS). (3) The differences between simulated Reco, NEE and GEE derived from MLE and those derived from OLS are 12.18% (176 g C·m-2·a-1), 34.33% (79 g C·m-2·a-1) and 5.4% (92 g C·m-2·a-1). However, for a given parameter optimization method, a temperature-dependent model (T_model) and the models derived from a temperature and water-dependent model (TW_model) are 1.31% (17.8 g C·m-2·a-1), 2.1% (5.7 g C·m-2·a-1), and 0.26% (4.3 g C·m-2·a-1), respectively, which suggested that the optimization methods are more important than the ecological models in influencing uncertainty in estimated carbon fluxes. (4) The relative uncertainty of CO2 flux derived from OLS is higher than that from MLE, and the uncertainty is related to timescale, that is, the larger the timescale, the smaller the uncertainty. The relative uncertainties of Reco, NEE and GEE are 4%-8%, 7%-22% and 2%-4% respectively at annual timescale.

关键词： CO2 flux components statistical uncertainty analysis bootstrapping method subtropical evergreen coniferous plantation Qianyanzhou