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Association of physical activity with risk of chronic kidney disease in China:A population-based cohort study

Journal of Sport and Health Science 2024年第2期13卷 204-211页

作者： Kexiang Shi Yunqing Zhu Jun Lv Dianjianyi Sun Pei Pei Huaidong Du yiping chen Ling Yang Bing Han Rebecca Stevens Junshi chen Zhengming chen Liming Li Canqing Yu China Kadoorie Biobank collaborative group Department of Epidemiology&Biostatistics School of Public HealthPeking University Health Science CenterBeijing 100191China Peking University Center for Public Health and Epidemic Preparedness&Response Beijing 100191China Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijing 100191China Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxford OX37LFUK Medical Research Council Population Health Research Unit at the University of Oxford Oxford OX37LFUK NCDs Prevention and Control Department Henan Center for Disease Control and PreventionZhengzhou 450016China China National Center for Food Safety Risk Assessment Beijing 100022China 不详

Background:Information on the association between physical activity(PA)and the risk of chronic kidney disease(CKD)is *** aimed to explore the associations of total,domain-specific,and intensity-specific PA with CKD and its subtypes in ***:The study included 475,376 adults from the China Kadoorie Biobank aged 30-79 years during 2004-2008 at *** interviewer-administered questionnaire was used to collect the information about PA,which was quantified as metabolic equivalent of task hours per day(MET-h/day)and categorized into 4 groups based on *** regression was used to analyze the association between PA and CKD ***:During a median follow-up of 12.1 years,5415 incident CKD cases were documented,including 1159 incident diabetic kidney disease(DKD)cases and 362 incident hypertensive nephropathy(HTN)*** PA was inversely associated with CKD risk,with an adjusted hazard ratio(HR,95%confidence interval(95%CI))of 0.83(0.75-0.92)for incident CKD in the highest quartile of total PA as compared with participants in the lowest *** results were observed for risk of DKD and HTN,and the corresponding HRs(95%CIs)were 0.75(0.58-0.97)for DKD risk and 0.56(0.37-0.85)for HTN *** nonoccupational PA,low-intensity PA,and moderate-to-vigorous-intensity PA were significantly associated with a decreased risk of CKD,with HRs(95%CIs)of 0.80(0.73-0.88),0.85(0.77-0.94),and 0.85(0.76-0.95)in the highest quartile,***:PA,including nonoccupational PA,low-intensity PA,and moderate-to-vigorous-intensity PA,was inversely associated with the risk of CKD,including DKD,HTN,and other CKD,and such associations were dose dependent.

关键词： Chronic kidney disease Domain Intensity Physical activity

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The Association Between Preserved Ratio Impaired Spirometry and Mortality –– 10 CKB Study Areas, China, 2004–2022

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China CDC weekly 2024年第43期6卷 1120-1125,I0003页

作者： Yalei Ke Xinyi Zhang Dianjianyi Sun Pei Pei Huaidong Du yiping chen Ling Yang Xiaoming Yang Kang Wang Junshi chen Zhengming chen Jun Lv Liming Li Canqing Yu Department of Epidemiology and Biostatistics School of Public HealthPeking University Health Science CenterBeijingChina Peking University Center for Public Health and Epidemic Preparedness&Response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUK Shibei Center for Disease Control and Prevention Qingdao CityShandong ProvinceChina China National Center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina.

What is already known about this topic?China has the world’s most significant public health and economic burden of chronic respiratory ***,the association between preserved ratio impaired spirometry(PRISm)and mortality risk is *** is added by this report?The PRISm group exhibited a 37%higher risk of allcause mortality than the normal group,and the risks of death from cardiovascular diseases,neoplasms,respiratory diseases,and infectious and parasitic diseases were also increased in ***,the presence of respiratory symptoms or disease was associated with an increased risk of mortality in *** are the implications for public health practice?It is imperative to enhance public awareness of PRISm and to implement measures to facilitate the regression of PRISm toward normal lung function.

关键词： function. impaired neoplasms

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Prevalence and Risk Factors for Chronic Obstructive Pulmonary Disease Among Adults Aged 50 and Above-10 CKB Study Areas,China,2020–2021

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China CDC weekly 2024年第43期6卷 1126-1131页

作者： Wei Yu Yongbing Lan Dianjianyi Sun Pei Pei Ling Yang yiping chen Huaidong Du Yingcai Yang Dan Schmidt Junshi chen Zhengming chen Jun Lyu Liming Li Canqing Yu Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityBeijingChina Peking University Center for Public Health and Epidemic Preparedness&Response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUnited Kingdom Shinan District Center for Disease Control and Prevention Qingdao CityShandong ProvinceChina China National Center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina.

What is already known about this topic?The prevalence of COPD in Chinese individuals aged 50 years and above was obviously higher than that in younger adults,but the risk factors for this age group were *** is added by this report?The prevalence was estimated at 12.8%and 5.7%for males and females over 50 in 2020–2021,with confirmed risk factors of cigarette smoking,a family history of respiratory diseases,respiratory symptoms,and a history of cough or respiratory diseases during *** are the implications for public health practice?The findings may help clinicians and the public identify individuals at high risk of COPD and take targeted measures in a timely manner.

关键词： respiratory diseases prevalence

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Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese

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Stroke & Vascular Neurology 2024年第4期9卷 399-406,I0044-I0065页

作者： Songchun Yang Zhijia Sun Dong Sun Canqing Yu Yu Guo Dianjianyi Sun Yuanjie Pang Pei Pei Ling Yang Iona Y Millwood Robin G Walters yiping chen Huaidong Du Yan Lu Sushila Burgess Daniel Avery Robert Clarke Junshi chen Zhengming chen Liming Li Jun Lv On behalf of the China Kadoorie Biobank Collaborative Group Department of Epidemiology&Biostatistics School of Public HealthPeking UniversityBeijingChina Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunanChina Peking University Center for Public Health and Epidemic Preparedness&Response BeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University) Ministry of EducationBeijingChina Fuwai Hospital Chinese Academy of Medical Sciences BeijingChina Medical Research Council Population Health Research Unit at the University of Oxford OxfordUK Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU) Nuffield Department of Population HealthUniversity of OxfordOxfordUK NCDs Prevention and Control Department Suzhou CDCSuzhouJiangsuChina China National Center for Food Safety Risk Assessment BeijingChina State Key Laboratory of Vascular Homeostasis and Remodeling Peking UniversityBeijingChina 不详

Background and purpose Previous studies,mostly focusing on the European population,have reported polygenic risk scores(PRSs)might achieve risk stratification of *** aimed to examine the association strengths of PRSs with risks of stroke and its subtypes in the Chinese *** Participants with genome-wide genotypic data in China Kadoorie Biobank were split into a potential training set(n=22191)and a population-based testing set(n=72150).Four previously developed PRSs were included,and new PRSs for stroke and its subtypes were *** PRSs showing the strongest association with risks of stroke or its subtypes in the training set were further evaluated in the testing *** proportional hazards regression models were used to estimate the association strengths of different PRSs with risks of stroke and its subtypes(ischaemic stroke(IS),intracerebral haemorrhage(ICH)and subarachnoid haemorrhage(SAH)).Results In the testing set,during 872919 person-years of follow-up,8514 incident stroke events were *** PRSs of any stroke(AS)and IS were both positively associated with risks of AS,IS and ICH(p<0.05).The HR for per SD increment(HR_(SD))of PRSAS was 1.10(95%CI 1.07 to 1.12),1.10(95%CI 1.07 to 1.12)and 1.13(95%CI 1.07 to 1.20)for AS,IS and ICH,*** corresponding HR_(SD) of PRS_(IS) was 1.08(95%CI 1.06 to 1.11),1.08(95%CI 1.06 to 1.11)and 1.09(95%CI 1.03 to 1.15).PRS_(ICH) was positively associated with the risk of ICH(HR_(SD)=1.07,95%CI 1.01 to 1.14).PRSS_(AH) was not associated with risks of stroke and its *** addition of current PRSs offered little to no improvement in stroke risk prediction and risk *** In this Chinese population,the association strengths of current PRSs with risks of stroke and its subtypes were moderate,suggesting a limited value for improving risk prediction over traditional risk factors in the context of current genome-wide association study under-representing the East Asia

关键词： testing prediction increment

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Miles术后会阴疝的预防及治疗进展

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中华消化外科杂志 2024年第9期23卷 1163-1167页

作者：翁山耕陈易平张翔福建医科大学附属第一医院肝胆胰、疝外科福建省腹部外科研究所福州350005

会阴疝根据病因可分为先天性和获得性会阴疝,而获得性会阴疝包括原发性和继发性会阴疝,其中先天性和原发性会阴疝十分罕见。继发性会阴疝中最常见为Miles术后会阴疝,Miles术中关闭盆底腹膜可有效减少其发生。对于术后会阴疝,手术修补是... 详细信息

会阴疝根据病因可分为先天性和获得性会阴疝,而获得性会阴疝包括原发性和继发性会阴疝,其中先天性和原发性会阴疝十分罕见。继发性会阴疝中最常见为Miles术后会阴疝,Miles术中关闭盆底腹膜可有效减少其发生。对于术后会阴疝,手术修补是唯一治疗手段,但目前尚无可指导临床诊断与治疗的共识及指南。笔者综合文献资料结合团队经验,推荐优先选择经腹入路应用合成补片修补;可先采用腹腔镜探查,必要时中转开腹;对于复杂困难患者可考虑腹会阴部联合入路,还可采用合成补片联合肌筋膜瓣修补;补片修补需注意固定位置及妥善塑形以达到充分固定、减少复发的目的。

关键词：会阴疝疝修补术补片腹会阴联合切除预防治疗

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可学习深度位置编码引导的车前图像道路可行驶区域检测

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武汉大学学报（信息科学版） 2024年第4期49卷 582-594页

作者：韩汀陈思宇马津蔡国榕张吴明陈一平中山大学测绘科学与技术学院广东珠海519082 集美大学计算机工程学院福建厦门361021

道路可行驶区域检测是汽车辅助驾驶系统中场景感知的关键基础。基于卷积神经网络的方法因难以获取全局上下文信息而易产生道路空洞和中断等完整性问题,而基于Transformer的方法缺乏局部理解,容易造成边界的错位和越界问题。为了克服上... 详细信息

道路可行驶区域检测是汽车辅助驾驶系统中场景感知的关键基础。基于卷积神经网络的方法因难以获取全局上下文信息而易产生道路空洞和中断等完整性问题,而基于Transformer的方法缺乏局部理解,容易造成边界的错位和越界问题。为了克服上述两类方法的缺陷,提出了一种可学习深度位置编码引导的金字塔Transformer网络架构,融合卷积神经网络与Transformer进行道路可行驶区域检测。该框架建立金字塔Transformer主干网从全局感受野提取道路特征,并结合局部窗口注意力弥补细节损失,以收缩自注意力提升特征计算效率。针对Transformer中传统位置编码忽略像素与实际场景空间关联性的问题,提出用深度图像卷积特征构建可学习位置编码的方法,解决现实关联性脱节引起的注意力偏移和语义不对齐问题。在KITTI道路、Cityscapes与自建厦门市道路数据集上对该方法进行了测试和评估,结果表明,该方法在保证较高效率的同时,具有较高的稳定性和精确性,其最大F值在KITTI和Cityscapes数据集上分别达到97.53%和98.54%,优于目前KITTI道路基准测试的所有方法。此方法可为汽车驾驶辅助系统的路径规划与轨迹预测等任务提供高精度的语义先验信息。

关键词： Transformer 位置编码道路感知可行驶区域检测自动驾驶

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Ecophysiological responses of winter wheat seedling to aerosol wet deposition of Xi'an area, China

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Journal of Environmental Sciences 2010年第11期22卷 1786-1791页

作者： yiping chen State Key Laboratory of Loess and Quaternary Geology Institute of Earth Environment Chinese Academy of Sciences Xi'an 710075 China.

Aerosol leads to 30% reduction in solar radiation reaching the earth’s surface, and a similar reduction in crops yield for both wheat and rice. To determine the effect of aerosol wet deposition on crops, aerosol samples were collected in September, 2006 at Xi’an urban suburb （34 44 N, 109 49 E）, and wheat seedlings were treated with aerosol of different concentrations in laboratory conditions. Changes in physiological and biochemical parameters of wheat seedlings were measured. In comparison with the control, the activities of superoxide dismudase （SOD） and catalase （CAT） and the concentration malondialdehyde （MDA） and oxidized glutathione （GSSG） of wheat seedlings increased progressively with increasing concentrations of added aerosol, while the opposite trend was seen for the activities of nitric oxide synthase （NOS）, the concentrations of glutathione （GSH） and nitric oxide （NO）, and the ratio of GSH/GSSG. When the seedlings were treated with the aerosol of 1 and 2 mg/L, the coleoptile elongation, shoot elongation and biomass accumulation were increased, the effect at treatment of 2 mg/L was most significant. However, aerosol treatments with rates of 3 and 4 mg/L resulted in a decrease in coleoptile elongation, shoot elongation and biomass accumulation in seedlings, and significant effect was for the treatment of 4 mg/L. Hence, lower concentrations of aerosol wet deposition were in favor of crops growth, but its higher concentrations could result in deleterious effects for crops and decreased crops growth.

关键词： aerosol deposition environment pollution air pollution ecotoxicological testing aerosol risk assessment

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党内政治文化:结构、功能与发展路径

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理论建设 2024年第1期40卷 1-7页

作者：陈义平安徽省社会科学院安徽合肥230051

习近平总书记关于发展积极健康的党内政治文化的重要论述,是对中国共产党百年党内政治文化建设经验的总结升华,是新时代加强执政党文化建设的战略部署和前进指南,是习近平文化思想中具有原创性贡献的重要组成部分。党内政治文化由“党... 详细信息

习近平总书记关于发展积极健康的党内政治文化的重要论述,是对中国共产党百年党内政治文化建设经验的总结升华,是新时代加强执政党文化建设的战略部署和前进指南,是习近平文化思想中具有原创性贡献的重要组成部分。党内政治文化由“党内制度文化—党内精神文化—党内行为文化”三维一体组成。发展积极健康的党内政治文化,必须着眼于党内政治文化的内在结构及其功能,一体推进良法善治的党内制度文化、凝心铸魂的党内精神文化、清廉担当的党内行为文化建设,以持续深入营造风清气正的党内政治生态环境,展现党内政治生活新气象。

关键词：习近平文化思想党内政治文化党内制度文化党内精神文化党内行为文化

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面向地外天体熔岩管的三维探测与形态研究

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深空探测学报（中英文） 2024年第4期11卷 346-354页

作者：杜雨萌陈一平张帅张吴明中山大学测绘科学与技术学院珠海519082

针对地外天体熔岩管探测,利用激光雷达技术对与月球、火星具有较高相似度的海口市石山火山群区域内的熔岩管进行了实地勘测,提出了基于网格划分的天窗检测方法以及利用基于数据增强与多尺度特征学习网络的裂缝检测方法,对熔岩管内部结... 详细信息

针对地外天体熔岩管探测,利用激光雷达技术对与月球、火星具有较高相似度的海口市石山火山群区域内的熔岩管进行了实地勘测,提出了基于网格划分的天窗检测方法以及利用基于数据增强与多尺度特征学习网络的裂缝检测方法,对熔岩管内部结构进行探测及形态研究;使用便携式手持激光扫描仪对管道内部进行全方位扫描获得高精度点云数据,在ContextCapture软件中完成三维建模,对管道内特殊的微型地貌天窗及其内壁裂隙进行了自动化的检测与提取。实验结果表明,利用激光扫描仪搭配点云处理软件及程序可以高效、直观且真实地还原熔岩管的形态结构,进行定量化分析,对管道内特殊的微型地貌可进行检测与提取。

关键词：熔岩管地外基地三维建模形态分析

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治沟造地工程对小流域氮磷面源污染的综合治理效应

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中国水土保持科学 2024年第3期22卷 64-71页

作者：曹婧陈怡平毋俊华张晶陈静书中国科学院地球环境研究所黄土与第四纪地质国家重点实验室西安710061 中国科学院大学北京100049 西安地球环境创新研究院西安710061

治沟造地工程可缓解黄土高原耕地资源紧张、人地矛盾等问题,对小流域水土流失也有很好的防治效果,但该工程对小流域水土流失型非点源污染的综合治理效应尚不明确。选取延安地区典型未治理流域与治沟造地流域、典型新造地和坡耕地、生态... 详细信息

治沟造地工程可缓解黄土高原耕地资源紧张、人地矛盾等问题,对小流域水土流失也有很好的防治效果,但该工程对小流域水土流失型非点源污染的综合治理效应尚不明确。选取延安地区典型未治理流域与治沟造地流域、典型新造地和坡耕地、生态拦截坝作为研究对象,采集并测定土样氮磷质量分数和水样氮磷质量浓度。结果表明:连年耕作新造地耕作层土壤氮磷质量分数显著高于传统坡耕地(P全年期>丰水期,治沟造地工程对流域水体氮磷质量浓度削减率排序为总磷>总氮>氨氮>硝氮;治沟造地对流域总氮拦截量最大,其次为硝氮。总体上,治沟造地工程能够在“源头”和“过程”对氮磷面源污染物进行双重阻截。

关键词：氮磷面源污染治沟造地小流域生态拦截坝南沟模式

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