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The Elongation Performance of Spirulina-templated Silver Micro Springs Embedded in the Polydimethylsiloxane

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Journal of Bionic Engineering 2017年第4期14卷 631-639页

作者： Jun Cai yingying shi Xinghao Li Deyuan Zhang School of Mechanical Engineering and Automation Beihang University Beijing 100191 China

Helical conductive particles have attracted much attention in preparing stretchable conductive materials because of their structural flexibility and uniform strain distribution under deformation. In this paper, Spirulina-templated silver micro springs were fabricated using electroless deposition of silver onto Spirulina surface. To investigate their potential application as con- ductive fillers for stretchable materials, they were mixed into polydimethylsiloxane （PDMS） uniformly, and then the mixture was spin coated on a polyfluortetraethylene （PTFE） plate to form a thin film, during which, micro springs tended to align its major axis along the radial direction of the plate. The tensile tests of micro springs were carried out using the film along the alignment direction of micro springs on the custom-made setup. Under the optimal condition of coating thickness of 0.67 gm, helical pitch of 29 gm and annealing temperature of 300 ~C, the average elongation of micro springs can reach up to -106.9%, which indicates that the as-prepared Spirulina-templated silver micro springs are promising flexible conductive fillers for fabricating stretchable conductive materials.

关键词： micro springs elongation electroless deposition of silver Spirulina stretchable conductive fillers

Impact of COVID-19 Interventions on Respiratory and Intestinal Infectious Disease Notifications-Jiangsu Province,China,2020–2023

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China CDC weekly 2024年第41期6卷 1059-1064,I0003页

作者： Ziying Chen Xin Liu Jinxing Guan yingying shi Wendong Liu Zhihang Peng Jianli Hu School of Public Health Nanjing Medical UniversityNanjing CityJiangsu ProvinceChina Department of Acute Infectious Diseases Control and Prevention Jiangsu Provincial Center for Disease Control and PreventionNanjing CityJiangsu ProvinceChina National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases Chinese Center for Disease Control and PreventionBeijingChina Jiangsu Province Engineering Research Center of Health Emergency Nanjing CityJiangsu ProvinceChina.

Introduction:Many measures implemented to control the coronavirus disease 2019(COVID-19)pandemic have reshaped the epidemic patterns of other infectious *** study estimated the impact of the COVID-19 pandemic on respiratory and intestinal infectious diseases and potential changes following ***:The optimal intervention and counterfactual models were selected from the seasonal autoregressive integrated moving average(SARIMA),neural network autoregression(NNAR),and hybrid models based on the minimum mean absolute percentage error(MAPE)in the test *** relative change rate between the actual notification rate and that predicted by the optimal model was calculated for the entire COVID-19 epidemic prevention period and the“reopening”***:Compared with the predicted notification rate based on the counterfactual model,the total relative change rates for the 9 infectious diseases were−44.24%,respiratory infections(−55.41%),and intestinal infections(−26.59%)during 2020–*** with the predicted notification rate based on the intervention model,the total relative change rates were+247.98%,respiratory infections(+389.59%),and intestinal infections(+50.46%)in *** them,the relative increases in influenza(+499.98%)and hand-foot-mouth disease(HFMD)(+70.97%)were ***:Measures taken in Jiangsu Province in response to COVID-19 effectively constrained the spread of respiratory and intestinal infectious *** and HFMD rebounded significantly after the lifting of COVID-19 intervention restrictions.

关键词： Impact lifting prevention

The long non-coding RNA expression profile of Coxsackievirus A16 infected RD cells identified by RNA-seq

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Virologica Sinica 2016年第2期31卷 131-141页

作者： yingying shi Huilin Tu Xiong Chen yingying Zhang Liujun Chen Zhongchun Liu Jiqun Sheng Song Han Jun Yin Biwen Peng Xiaohua He Wanhong Liu Pathogenic Organism and Infectious Diseases Research Institute School of Basic Medical SciencesWuhan University Wuhan 430071 China Hubei Province Key Laboratory of Allergy and Immunology Wuhan 430071 China Hubei Provincial Key Laboratory of Developmentally Originated Disease School of Basic Medical Sciences Wuhan University Wuhan 430071 China Institute of Neuropsychiatry Renmin Hospital Wuhan University Wuhan 430060 China College of Life Science and Technology Hubei Engineering University Xiaogan 432000 China

Coxsackievirus A16(CVA16) is one of major pathogens of hand, foot and mouth disease(HFMD) in children. Long non-coding RNAs(Inc RNAs) have been implicated in various biological processes,but they have not been associated with CVA16 infection. In this study, we comprehensively characterized the landscape of Inc RNAs of normal and CVA16 infected rhabdomyosarcoma(RD)cells using RNA-Seq to investigate the functional relevance of Inc RNAs. We showed that a total of 760 Inc RNAs were upregulated and 1210 Inc RNAs were downregulated. Out of these dysregulated Inc RNAs, 43.64% were intergenic, 22.31% were sense, 15.89% were intronic, 8.67% were bidirectional, 5.59% were antisense, 3.85% were s RNA host Inc RNAs and 0.05% were enhancer. Six dysregulated Inc RNAs were validated by quantitative PCR assays and the secondary structures of these Inc RNAs were projected. Moreover, we conducted a bioinformatics analysis of an Inc RNAs(ENST00000602478) to elucidate the diversity of modification and functions of Inc RNAs. In summary, the current study compared the dysregulated Inc RNAs profile upon CVA16 challenge and illustrated the intricate relationship between coding and Inc RNAs transcripts. These results may not only provide a complete picture of transcription in CVA16 infected cells but also provide novel molecular targets for treatments of HFMD.

关键词： RNA transcripts infected bidirectional bioinformatics illustrated enhancer picture landscape genomic

Retinal nerve fiber layer (RNFL) integrity and its relations to retinal microvasculature and microcirculation in myopic eyes

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Eye and Vision 2018年第1期5卷 223-232页

作者： Dongyi Qu Ying Lin Hong Jiang Yi Shao yingying shi Shriya Airen Giovanni Gregori Jianhua Wang Bascom Palmer Eye Institute University of Miami Miller School of MedicineMiamiFLUSA State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhouGuangdongChina Department of Neurology University of Miami Miller School of MedicineMiamiFLUSA College of Arts and Sciences University of MiamiMiamiFLUSA Department of Ophthalmology Bascom Palmer Eye Institute 1638 NW 10th AvenueMcKnight Building-Room 202AMiamiFL 33136USA

Background:The aim was to determine retinal nerve fiber layer function and its relations to retinal microvasculature and microcirculation in patients with ***:Polarization-sensitive optical coherence tomography(PS-OCT)was used to measure phase retardation per unit depth(PR/UD,proportional to the birefringence)of the retinal nerve fiber layer(RNFL).Optical coherence tomography angiography(OCTA)was used to measure macular vessel density analyzed using fractal *** addition,a retinal function imager(RFI)was used to measure macular blood flow velocities in arterioles and ***-two patients with moderate myopia(MM,refraction>3 and0.05).The macular vessel density in both superficial and deep vascular plexuses was significantly lower in the HM group than in the other two groups(P0.05).Conclusions:The impairment of the retinal nerve fiber birefringence in the HM group may be one of the independent features in high myopic eyes,which appeared not to relate to macular microvascular density and blood flow velocity.

关键词： Myopia Retinal nerve fiber layer Polarization-sensitive optical coherence tomography Retinal blood flow velocity Retinal function imager Retinal microvasculature Optical coherence tomography angiography

Effects of Dietary Changes on the Gut Microbiota of Cynops orientalis

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Asian Herpetological Research 2024年第2期15卷 63-72页

作者： Yuting WANG Yuning XIE Siyu WU Wenwen ZHANG Xiner CHENG Zixuan LI Fangfei HAN Jiayi shi yingying shi Zhirong HE Chunna ZHANG Yixin JIANG Na ZHAO Jiaqi LI Supen WANG College of Life Sciences Anhui Normal UniversityWuhu 241000AnhuiChina Nanjing Institute of Environmental Sciences Ministry of Ecology and Environment of ChinaNanjing 210042JiangsuChina School of Ecology and Environment Anhui Normal UniversityWuhu 241002AnhuiChina Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China

The gut microbiota plays a pivotal role in the maintenance of health for amphibians,and it has been fully recognized,but the effectiveness of various influencing factors has not yet been fully *** this association should be considered while the amphibian order Caudata is facing a severe situation of population decline and extinction,there is little understanding of the association between diets and the diversity of gut microbiota in the amphibian order ***,we conducted an extensive analysis of the gut microbiota of Cynops orientalis fed different diets using functional prediction and 16S rRNA amplicon sequencing ***,we found that wild individuals had greater gut microbial diversity and richness in comparison to captive ***,we identified the bacterial taxa associated with diets and observed differences in the relative abundance of gut microbiota among people on various ***,we have a predictive comprehension of the selection and adaptative significance of shared core ASVs in the gut microbiota in maintaining the healthy survival of *** in a large-scale spatiotemporal *** study emphasizes how diets alter the gut microbiota of Caudata and offers fresh perspectives on the conservation and captive management of species in Caudata.

关键词： 16S rRNA Caudata core microbiota diet gut microbiota

A case report on retroperitoneal PNET/EWS

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Case Reports in Clinical Medicine 2013年第6期2卷 366-369页

作者： Zhanqiang Zhang Honglan Yu yingying shi Hanping shi Department of Surgery The First Affiliated Hospital Sun Yet-sen University Guangzhou China Department of Surgery The First Affiliated Hospital Sun Yet-sen University Guangzhou China

Primitive neuroectodermal tumor (PNET) and Ewing’s sarcoma (EWS) are small round cell tumors occurring mainly in children and adolescents, rarely in adults. It can occur in multiple tissues and organs including kidney, adrenal, bladder, liver, small intestine, colon and rectum, with a preferred location within the chest area, in the limbs and around the spine, but with rare cases of abdominal, pelvic or retroperitoneal. Here we present a case of the retroperitoneal PENT/EWS in a 38-year-old man and we discuss the clinical features, histopathological characteristics, diagnosis, treatment and prognosis.

关键词： Retroperitoneal Sarcoma Primitive Neuroectodermal Tumor Ewing’s Sarcoma

Trends in disease burden of hepatitis B infection in Jiangsu Province,China,1990-2021

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Infectious Disease Modelling 2023年第3期8卷 832-841页

作者： Kang Fang yingying shi Zeyu zhao Yunkang Zhao Yichao Guo Buasivamu Abudunaibi Huimin Qu Qiao Liu Guodong Kang Zhiguo Wang Jianli Hu Tianmu Chen State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics School of Public HealthXiamen UniversityXiamen City361102Fujian ProvincePeople's Republic of China Jiangsu Provincial Center for Disease Control and Prevention Nanjing CityPeople's Republic of China

Background:The incidence of hepatitis B virus(HBV)has decreased year by year in China after the expansion of vaccination,but there is still a high disease burden in Jiangsu Province of ***:The year-by-year incidence data of HBV in Jiangsu Province from 1990 to 2021 were *** incidence rates of males and females age groups were clustered by systematic clustering,and the incidence rates of each age group were analyzed and studied by using Joinpoint regression model and age-period-cohort effect model(APC).Results:Joinpoint regression model and APC model showed a general decrease in HBV prevalence in both males and *** addition,the results of the APC model showed that the age,period,and cohort effects of patients all affected the incidence of HBV,and the incidence was higher in males than in *** incidence is highest in the population between the ages of 15 and 30 years(mean:21.76/100,000),especially in males(mean:31.53/100,000)than in females(mean:11.67/100,000).Another high-risk group is those over 60 years of age(mean:21.40/100,000),especially males(mean:31.17/100,000)than females(mean:11.63/100,000).The period effect of the APC model suggests that HBV vaccination is effective in reducing the incidence of HBV in the ***:The incidence of HBV in Jiangsu Province showed a gradual downward trend,but the disease burden in males was higher than that in *** incidence is higher and increasing rapidly in the population between the ages of 15 and 30 years and people over 60 years of *** targeted prevention and control measures should be imple-mented for males and the elderly.

关键词： HBV Joinpoint regression model Age-period-cohort model Systematic clustering

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构筑“以审判为中心”诉讼制度诸要件的思考

政法论坛 2016年第1期34卷 160-166页

作者：石莹莹华东政法大学

以审判为中心的诉讼制度,要求把审判程序置于刑事诉讼的核心程序,通过审判程序对案件进行全面、实质性审查,整个诉讼制度围绕审判而建构,全部诉讼活动围绕审判而展开。要建立以审判为中心的诉讼制度,必须牢牢把握以下四要件:确立共同的... 详细信息

以审判为中心的诉讼制度,要求把审判程序置于刑事诉讼的核心程序,通过审判程序对案件进行全面、实质性审查,整个诉讼制度围绕审判而建构,全部诉讼活动围绕审判而展开。要建立以审判为中心的诉讼制度,必须牢牢把握以下四要件:确立共同的诉讼理念,构建"审判中心"前提;坚持统一的证据证明标准,夯实"审判中心"基础;完善控辩平等对抗机制,紧扣"审判中心"关键;发挥庭审决定作用,抓住"审判中心"根本。

关键词：诉讼理念证据标准控辩平等庭审中心

表演艺术的数字化国际传播路径探索——以国家大剧院线上演出的海外播出为例

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人民音乐 2022年第4期 65-67页

作者：侍莹莹国家大剧院品牌中心

2021年12月11日晚,国家大剧院线上演出第100期特别策划“画韵京音——走进画家姜国芳工作室线上音乐会”通过国家大剧院古典音乐频道、世界剧院联盟平台、央视网、Facebook、You Tube等近六十家国内外媒体平台面向全球播出,总点击量286... 详细信息

2021年12月11日晚,国家大剧院线上演出第100期特别策划“画韵京音——走进画家姜国芳工作室线上音乐会”通过国家大剧院古典音乐频道、世界剧院联盟平台、央视网、Facebook、You Tube等近六十家国内外媒体平台面向全球播出,总点击量2866.8万次,覆盖海外受众82.8万人次,引发国内外网友如潮好评。至此,国家大剧院线上演出已播出逾百场,全网总点击量达29.05亿次,覆盖海外受众1700万人次。

关键词：国家大剧院表演艺术音乐频道国内外媒体工作室央视网点击量 100期

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