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Safety and feasibility of transradial coronary intervention in Chinese elderly patients

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Journal of Geriatric Cardiology 2007年第1期4卷 14-16页

作者： Quanmin JING Yaling HAN Shouli WANG yingyan ma Bo LUAN Huiquan ZHAO Department of Cardiology Shenyang General Hospital of Chinese PLAShenyang 110016China The Liaoyang Third Hospital Liaoyang 110000China

Objective To assess the feasibility and safety of transradial approach in Chinese elderly patients undergoing coronary *** In this prospective study,764 elderly patients with coronary artery disease received percutaneous coronary intervention via either a transradial approach(TRA group)or a transfemoral approach(TFA group).The procedural success rate,success rate of artery access,puncture time,fluoroscopy time,dose of contrast,local complications and post-procedural pulmonary embolism were recorded and compared between 2 *** There was no significant difference of the procedural success rate between the TRA group and the TRF group(96.3%vs.98.2%,P>0.05);there were also no differences of success rate of cannulation,mean fluoroscopy time and mean dose of contrast between the 2 *** mean puncture time was longer in the TRA group than in the TFA group(3.8±2.1 min vs.2.0±3.4 min,P<0.05).However,there were fewer access site-related complications in the TRA group than in the TFA ***-procedural pulmonary embolism occurred in 2 patients in the TFA group but none in the TRA *** Transradial coronary intervention was feasible and safe in most Chinese elderly patients when performed by experienced operators.

关键词： percutaneous coronary intervention radial artery stent elderly Chinese

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降脂治疗的新选择:PCSK9抑制剂

中华心血管病杂志 2019年第2期47卷 164-167页

作者：马颖艳韩雅玲北部战区总医院心内科全军心血管病研究所沈阳110016

血脂异常是冠心病的危险因素之一,临床上越来越重视调脂治疗,但在实际工作中,常见大剂量他汀类药物难以控制的高胆固醇血症和低密度脂蛋白胆固醇血症。前蛋白转化酶枯草溶菌素9(PCSK9)是近期发现的非他汀类降脂药物的新靶点,alirocumab... 详细信息

血脂异常是冠心病的危险因素之一,临床上越来越重视调脂治疗,但在实际工作中,常见大剂量他汀类药物难以控制的高胆固醇血症和低密度脂蛋白胆固醇血症。前蛋白转化酶枯草溶菌素9(PCSK9)是近期发现的非他汀类降脂药物的新靶点,alirocumab是一种全人源IgGl型单克隆抗体,作为PCSK9抑制剂,能结合PCSK9并抑制循环型PCSK9与低密度脂蛋白受体结合,从而阻止PCSK9介导的低密度脂蛋白受体降解。该药可用于治疗成人杂合子型家族性高胆固醇血症和临床动脉粥样硬化性疾病,对防治心血管疾病具有重大意义。

关键词：血脂异常高胆固醇血症 PCSK9抑制剂

Retrospective Study on the Relation between the Level of Thyroid Hormone and Coronary Atherosclerotic Heart Disease

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Age, estimated glomerular filtration rate and ejection fraction score predicts contrast-induced acute kidney injury in patients with diabetes and chronic kidney disease： insight from the TRACK-D study

中华医学会第十五次全国心血管病学大会

作者： yingyan ma Yan-Xia Wang Wei Dong Ya-Bin Liu Ya-Ling Han Department of Cardiology Institute of Cardiovascular Research of People’s Liberation Army Shenyang Northern Hospital

Background To observe the changes of the level of thyroid hormone in the patients with coronary atherosclerotic heart disease (CHD). Methods According to the results of coronary artery angiography, 299 patients were divided into experimental group (n=208) and control group (n=91). And the experimental group were divided into three groups: the single vessel disease group(n=72), the double vessel disease group(n=87)and the triple vessel

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Chinese Medical Journal 2014年第12期127卷 2332-2336页

作者： Li Jing Li Yi Wang Xiaozeng Yang Shuguang Gao Chuanyu Zhang Zheng Yang Chengming Jing Quanming Wang Shouli ma yingyan Wang Zulu Liang Yanchun Han Yaling Department of Cardiology Shenyang Northern HospitalShenyangLiaoning 110016China Department of Cardiology Jinan Military 88th HospitalTaianShandong 271000China Department of Cardiology Henan Provincial Peoples HospitalZhengzhouHenan 450003China Department of Cardiology First Affiliated Hospital of Lanzhou UniversityLanzhouGansu 730000China Department of Cardiology Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityChongqing 400038China Depal tment of Cardiology The 306th'Hospital of People's LiberationArmy Beijing 10000 China

Background The occurrence of contrast induced acute kidney injury （CIAKI） has a pronounced impact on morbidity and *** aim of the present study was to appraise the diagnostic efficacy of age,estimated glomerular filtration rate （eGFR） and ejection fraction （AGEF） score （age/EF（％）＋1 （if eGFR was ＜60 ml·min-1·1.73 m2）） as an predictor of CIAKI in patients with diabetes mellitus （DM） and concomitant chronic kidney disease （CKD）.Methods The AGEF score was calculated for 2 998 patients with type 2 DM and concomitant CKD who had undergone coronary/peripheral arterial *** was defined as an increase in sCr concentration of 0.5 mg/dl （44.2 mmol/L） or 25％ above baseline at 72 hours after exposure to the contrast *** hoc analysis was performed by stratifying the rate of CIAKI according to AGEF score *** diagnostic efficacy of the AGEF score for predicting CIAKI was evaluated with receiver operating characteristic （ROC） *** The AGEF score ranged from 0.49 to *** AGEF score tertiles were defined as follows：AGEFlow ≤0.92 （n=1 006）; 0.92 ＜AGEFmid ≤1.16 （n=1 000）,and ACEFhigh ＞1.16 （n=992）.The incidence of CIAKI was significantly different in patients with low,middle and high AGEF scores （AGEFlow=1.1％,AGEFmid=2.3％ and AGEFhigh=5.8％,P ＜0.001）.By multivariate analysis,AGEF score was an independent predictor of CIAKI （odds ratio=4.96,95％ CI：2.32-10.58,P ＜0.01）.ROC analysis showed that the area under the curve was 0.70 （95％ CI：0.648-0.753,P ＜0.001）.Conclusion The AGEF score is effective for stratifying risk of CIAKI in patients with DM and CKD undergoing coronary/peripheral arterial angiography.

关键词： AGEF score contrast induced acute kidney injury diabetes chronic kidney disease

依据《中小学生屈光不正筛查规范》开展青少年屈光不正防控工作

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中华实验眼科杂志 2020年第6期38卷 473-475页

作者：邹海东何鲜桂马莹琰马军董彬许迅上海市眼病防治中心上海市眼科医院 200040 上海交通大学附属第一人民医院 200080 北京大学儿童青少年卫生研究所 100191

屈光不正性视力损害已成为我国乃至全球范围内的公共卫生问题,儿童及青少年的近视防控工作已引起我国政府的高度重视,建立目标人群的视力健康档案、开展屈光不正的筛查是儿童及青少年近视防控工作的重要环节和有效措施。长期以来,由于... 详细信息

屈光不正性视力损害已成为我国乃至全球范围内的公共卫生问题,儿童及青少年的近视防控工作已引起我国政府的高度重视,建立目标人群的视力健康档案、开展屈光不正的筛查是儿童及青少年近视防控工作的重要环节和有效措施。长期以来,由于国内外均缺乏相关的筛查标准,我国在相关筛查工作中存在开展筛查工作的主体资质和管理混乱、筛查指标欠合理及其界值不统一、筛查质量控制不佳、操作方法不规范和结果反馈不科学等问题。在国家卫生健康委员会的推动和支持下,推荐性国家卫生行业标准WS/T 663-2019《中小学生屈光不正筛查规范》于2020年1月11日正式发布并定于2020年6月1日正式实施,为我国规范性开展儿童及青少年的屈光不正筛查工作提供技术标准和指导意见。依据《中小学生屈光不正筛查规范》积极开展儿童及青少年的屈光不正筛查和防控是现阶段我国各级医疗和教育机构的重要任务和责任。

关键词：屈光不正,中小学生筛查近视防控规范

Strengthening the reversal effect of lipid-lowering on patients with stable angina plaque

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Clinical investigation of effects of intravenous versus intra-coronary injection of tirofiban during primary PCI

中华医学会第十五次全国心血管病学大会

作者： Liyou Sui Quanmin Jing Haiwei Liu Bin Wang Shaoyi Guan Yaling Han yingyan ma Xiaozeng Wang Bing Tian Department of Cardiology Institute of Cardiovascular Research of People’s Liberation Army Shenyang Northern Hospital

Background To explore atorvastatin, a lipid-lowering therapy, and its reversal effect and safety on patients with stable angina plaques. Methods In 50 cases of patients with stable angina whose coronary artery CT display plaque narrow area were below 70%, in contrast with coronary artery angiography and intravascular ultrasound, some patients

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Clinical investigation of effects of intravenous versus intr...

基于Pathfinder的高校教学楼安全疏散仿真研究

中华医学会第十五次全国心血管病学大会

作者： yingyan ma Ya-Ling Han Quan-Min Jing Kai Xu Hai-Wei Liu Geng Wang Xiao-Zeng Wang Xin Zhao Department of Cardiology Institute of Cardiovascular Research of People’s Liberation Army Shenyang Northern Hospital

Background To investigate effects of intravenous versus intra-coronary injection of tirofiban on myocardial reperfusion during primary PCI in patients with STEMI. Methods A total of 314 patients admitted to our hospital with myocardial infarction within 12 hours were enrolled in this study. Three hundred milligrams aspirin and 600 mg clopidogrel were given before PCI.

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华北科技学院学报 2020年第3期17卷 105-110页

作者：马辉马映妍华北科技学院北京东燕郊065201

本文以某高校教学楼为研究对象,按照日间正常上课和夜间晚自习两种场景,运用Pathfinder软件进行仿真研究,分析各楼层人数、累计疏散人数与疏散时间的关系,疏散人员性别对疏散效率的影响等,以期为高校应急疏散演练、应急预案编制等提供... 详细信息

本文以某高校教学楼为研究对象,按照日间正常上课和夜间晚自习两种场景,运用Pathfinder软件进行仿真研究,分析各楼层人数、累计疏散人数与疏散时间的关系,疏散人员性别对疏散效率的影响等,以期为高校应急疏散演练、应急预案编制等提供依据。结果表明,日间场景人员疏散耗时893s,夜间场景耗时440s,疏散人数对疏散效率影响大;疏散起始位置分析显示疏散速度与疏散人员所处层位人员密度密切相关;疏散时间与疏散层累计人数呈正相关,与该层原始疏散人数关系不明显;疏散楼梯拥堵是安全疏散的瓶颈因素,楼梯处拥堵时性别差异对于疏散影响不明显。

关键词：教学楼安全疏散仿真 Pathfinder

知信行健康教育模式对糖尿病肾病患者透析低血糖及自护能力的影响

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糖尿病新世界 2023年第20期26卷 133-136页

作者：孙璐许阳马映艳扬州市第二人民医院血液净化中心江苏扬州225002

目的探讨知信行健康教育模式对糖尿病肾病患者透析低血糖及自护能力的影响。方法选取2022年1月—2023年3月扬州市第二人民医院收治的120例糖尿病肾病透析患者作为研究对象。根据抽签法将患者分为对照组和观察组,每组60例,对照组接受常... 详细信息

目的探讨知信行健康教育模式对糖尿病肾病患者透析低血糖及自护能力的影响。方法选取2022年1月—2023年3月扬州市第二人民医院收治的120例糖尿病肾病透析患者作为研究对象。根据抽签法将患者分为对照组和观察组,每组60例,对照组接受常规护理干预,观察组在对照组基础上接受知信行健康教育模式。对比两组患者干预效果。结果干预后,观察组自护能力评分高于对照组,差异有统计学意义(t=5.963,P<0.05)。干预后,观察组屈服维度、回避维度评分均低于对照组,差异有统计学意义(t=3.163、3.985,P<0.05);观察组面对维度评分高于对照组,差异有统计学意义(t=4.601,P<0.05)。观察组低血糖发生情况为0,低于对照组(8.33%),差异有统计学意义(χ2=5.220,P<0.05)。结论糖尿病肾病患者透析治疗过程中接受知信行健康教育模式,患者自护能力明显提升,能够积极应对疾病治疗,低血糖发生风险得以有效降低。

关键词：知信行健康教育模式糖尿病肾病透析低血糖自护能力