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基于成果导向教育理念的艺术类史论课程教学改革实践——以“世界建筑与环境设计发展史”课程为例

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唐山学院学报 2024年第3期37卷 84-89,108页

作者：李倩王欣于英丽陈强刘宜滨宋迎军唐山学院艺术系河北唐山063000 唐山雨潇农业科技有限公司河北唐山064002

基于成果导向教育理念,从制定教学改革目标、进行教学活动设计、制定多元化课程考核方式和构建课程评价体系等方面入手,探讨艺术类史论课程“世界建筑与环境设计发展史”的教学改革实践及其成效。结果表明:该课程教学改革实践效果良好,... 详细信息

基于成果导向教育理念,从制定教学改革目标、进行教学活动设计、制定多元化课程考核方式和构建课程评价体系等方面入手,探讨艺术类史论课程“世界建筑与环境设计发展史”的教学改革实践及其成效。结果表明:该课程教学改革实践效果良好,课程目标达成度较高,学生学业成绩优良,学习能力得到有效提升;同时教师教学质量显著提高,课程建设和教学团队建设成果丰硕,为后期课程教学持续性改进提供了思路。

关键词：成果导向艺术类史论课程教学改革环境设计专业

SmartEagleEye:A Cloud-Oriented Webshell Detection System Based on Dynamic Gray-Box and Deep Learning

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Tsinghua Science and Technology 2024年第3期29卷 766-783页

作者： Xin Liu yingli Zhang Qingchen yu Jiajun Min Jun Shen Rui Zhou Qingguo Zhou School of Information Science and Engineering Lanzhou UniversityLanzhou 730000China College of Computer Science and Technology Zhejiang UniversityHangzhou 310058China School of Computing and Information Technology University of WollongongWollongong 2500Australia

Compared with traditional environments,the cloud environment exposes online services to additional vulnerabilities and threats of cyber attacks,and the cyber security of cloud platforms is becoming increasingly prominent.A piece of code,known as a Webshell,is usually uploaded to the target servers to achieve multiple *** Webshell attacks has become a hot spot in current ***,the traditional Webshell detectors are not built for the cloud,making it highly difficult to play a defensive role in the cloud ***,a Webshell detection system based on deep learning that is successfully applied in various scenarios,is proposed in this *** system contains two important components:gray-box and neural network *** gray-box analyzer defines a series of rules and algorithms for extracting static and dynamic behaviors from the code to make the decision *** neural network analyzer transforms suspicious code into Operation Code(OPCODE)sequences,turning the detection task into a classification *** experiment results show that SmartEagleEye achieves an encouraging high detection rate and an acceptable false-positive rate,which indicate its capability to provide good protection for the cloud environment.

关键词： Webshell detection cloud web security deep learning

Life’s Essential 8 and risk of non-communicable chronic diseases:Outcome-wide analyses

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Chinese Medical Journal 2024年第13期137卷 1553-1562页

作者： yuetian yu Ying Sun yuefeng yu yuying Wang Chi Chen Xiao Tan yingli Lu Ningjian Wang Institute and Department of Endocrinology and Metabolism Shanghai Ninth People’s HospitalShanghai JiaoTong University School of MedicineShanghai 200011China School of Public Health Zhejiang UniversityHangzhou 310058ZhejiangChina Department of Medical Sciences Uppsala UniversityUppsala 75185Sweden

Background:Life’s Simple 7,the former construct of cardiovascular health(CVH)has been used to evaluate adverse non-communicable chronic diseases(NCDs).However,some flaws have been recognized in recent years and Life’s Essential 8 has been *** this study,we aimed to analyze the association between CVH defined by Life’s Essential 8 and risk of 44 common NCDs and further estimate the population attributable fractions(PAFs)of low-moderate CVH scores in the 44 ***:In the UK Biobank,170,726 participants free of 44 common NCDs at baseline were *** Life’s Essential 8 composite measure consists of four health behaviours(diet,physical activity,nicotine exposure,and sleep)and four health factors(body mass index,non-high density lipoprotein cholesterol,blood glucose,and blood pressure),and the maximum CVH score was 100 *** score was categorized into low,moderate,and high *** were followed up for 44 NCDs diagnosis across 10 human system disorders according to the International Classification of Diseases 10th edition(ICD-10)code using linkage to national health records until *** proportional hazard models were used in this *** hazard ratios(HRs)and PAFs of 44 NCDs associated with CVH score were ***:During the median follow-up of 10.85 years,58,889 incident NCD cases were *** linear dose-response associations were found between higher CVH score and lower risk of 25(56.8%)of 44 ***-moderate CVH(<80 points)score accounted for the largest proportion of incident cases in diabetes(PAF:80.3%),followed by gout(59.6%),sleep disorder(55.6%),chronic liver disease(45.9%),chronic kidney disease(40.9%),ischemic heart disease(40.8%),chronic obstructive pulmonary disease(40.0%),endometrium cancer(35.8%),lung cancer(34.0%),and heart failure(34.0%)as the top *** the eight modifiable factors,overweight/obesity explained the largest number of cases of incident NCDs in endocrine,nutritional,and me

关键词： Life’s Essential 8 Cardiovascular risk score Non-communicable chronic disease Population health management Cohort analysis Healthy lifestyle UK Biobank

Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods

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Chinese Chemical Letters 2024年第2期35卷 352-357页

作者： yingli Zhu Jie Qian Kunqian yu Jing Hou Yeshuo Ma Fei Chen Jie Dong Wenbin Zeng Xiangya School of Pharmaceutical Sciences Central South UniversityChangsha 410083China National Engineering Research Center of Rice and Byproduct Deep Processing School of Food Science and EngineeringCentral South University of Forestry and TechnologyChangsha 410004China State Key Laboratory of Drug Research Drug Discovery and Design CenterShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Department of Geriatrics Third Xiangya HospitalCentral South UniversityChangsha 410013China

Multifunctional molecules with both optical signal and pharmacological activity play an important role in drug development,disease diagnosis,and basic theoretical *** N(APN),as a representative tumor biomarker with anti-tumor potential,still lacks a high-precision theranostic probe specifically targeting *** this study,a novel quaternity design strategy for APN theranostic probe was *** proposed strategy utilizes advanced machine learning and molecular dynamics simulations,and cleverly employs the strategy of conformation-induced fluorescence recovery to achieve multi-objective optimization and integration of functional *** this strategy,a unique“Off-On”theranostic probe,ABTP-DPTB,was ingeniously constructed to light up APN through fluorescence restoration,relying on conformation-induced effects and solvent *** from the common diagnostic probes,the intelligent design with non-substrated linkage makes ABTP-DPTB for long-term in-situ *** fabricated probe was used for detecting and inhibiting APN in various environments,with a better in vitro inhibitory than golden-standard drug bestatin.

关键词： Theranostic probe Artificial intelligence Conformational restriction Fluorescence restoration Design strategy

Recent Progress of Aerosol Light-scattering Enhancement Factor Studies in China

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Advances in Atmospheric Sciences 2019年第9期36卷 1015-1026页

作者： Chunsheng ZHAO yingli yu Ye KUANG Jiangchuan TAO Gang ZHAO Department of Atmospheric and Oceanic Sciences School of PhysicsPeking UniversityBeijing 100871China Institute for Environmental and Climate Research Jinan UniversityGuangzhou 510632China

Assessment of the radiative forcing of aerosols in models still lacks sufficient input data for aerosol hygroscopicity. The light scattering enhancement factor [ f(RH, λ)] is a crucial parameter for describing aerosol hygroscopic growth *** this paper, we provide a survey of f(RH, λ) studies in China for the past seven years, including instrument developments of humidified nephelometers, ambient f(RH, λ) measurements in China, f(RH, λ) parameterization schemes, and f(RH, λ)applications in aerosol measurements. Comparisons of different f(RH, λ) parameterizations are carried out to check their performance in China using field measurement datasets. We also summary the parameterization schemes for predicting f(RH, λ)with aerosol chemical compositions. The recently developed methods to observe other aerosol properties using f(RH, λ)measurements, such as calculating the aerosol hygroscopicity parameter, cloud condensation nuclei number concentration,aerosol liquid water content, and aerosol asymmetry factor, are introduced. Suggestions for further research on f(RH, λ) in China are given.

关键词： aerosol hygroscopicity light-scattering enhancement factor humidified nephelometer

Birth weight,ideal cardiovascular health metrics in adulthood,and incident cardiovascular disease

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Chinese Medical Journal 2024年第10期137卷 1160-1168页

作者： Ying Sun Bin Wang yuefeng yu yuying Wang Xiao Tan Jihui Zhang Lu Qi yingli Lu Ningjian Wang Department of Endocrinology and Metabolism Institute of Endocrinology and MetabolismShanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China School of Public Health Zhejiang UniversityHangzhouZhejiang 310058China Department of Medical Sciences Uppsala UniversityUppsala 75105Sweden Center for Sleep and Circadian Medicine The Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhouGuangdong 510370China Department of Epidemiology School of Public Health and Tropical MedicineTulane UniversityNew OrleansLA 70118USA Department of Nutrition Harvard T.H.Chan School of Public HealthBostonMA 02138USA Channing Division of Network Medicine Department of MedicineBrigham and Women’s Hospital and Harvard Medical SchoolBostonMA 02138USA

Background:Prenatal and postnatal factors may have joint effects on cardiovascular health,and we aimed to assess the joint association of birth weight and ideal cardiovascular health metrics(ICVHMs)prospectively in adulthood with incident cardiovascular disease(CVD).Methods:In the UK Biobank,227,833 participants with data on ICVHM components and birth weight and without CVD at baseline were *** ICVHMs included smoking,body mass index,physical activity,diet information,total cholesterol,blood pressure,and hemoglobin *** Cox proportional hazards model was used to estimate the hazard ratios(HRs)and 95%confidence intervals(CIs)in men and ***:Over a median follow-up period of 13.0 years(2,831,236 person-years),we documented 17,477 patients with incident *** with participants with birth weights of 2.5-4.0 kg,the HRs(95%CIs)of CVD among those with low birth weights was 1.08(1.00-1.16)in men and 1.23(1.16-1.31)in *** association between having a birth weight<2.5 kg and CVD risk in men was more prominent for those aged<50 years than for those of older age(P for interaction=0.026).Lower birth weight and non-ideal cardiovascular health metrics were jointly related to an increased risk of *** with birth weights<2.5 kg and ICVHMs score 0-1 had the highest risk of incident CVD(HR[95%CI]:3.93[3.01-5.13]in men;4.24[3.33-5.40]in women).The joint effect(HR[95%CI]:1.36[1.17-1.58])could be decomposed into 24.7%(95%CI:15.0%-34.4%)for a lower birth weight,64.7%(95%CI:56.7%-72.6%)for a lower ICVHM score,and 10.6%(95%CI:2.7%-18.6%)for their additive interaction in ***:Birth weight and ICVHMs were jointly related to CVD *** a normal birth weight and ideal ICVHMs may reduce the risk of CVD,and a simultaneous improvement of both prenatal and postnatal factors could further prevent additional cases in women.

关键词： Birth weight Health metrics Cardiovascular disease Adult Stroke Coronary heart disease

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中药在2型糖尿病治疗中的研究进展

实用药物与临床 2024年第4期27卷 304-308页

作者：韩超郭万慧李小龙于英莉彭雁飞周昆王玉环孙力康天津中医药大学中医药研究院天津301600 天津中医药大学中西医结合学院天津301600 西安交通大学第二附属医院陕西西安710004

2型糖尿病(T2DM)的发病机制尚不明确,可能与胰岛素抵抗、炎症反应、氧化应激、脂质代谢异常、肠道菌群失调和遗传等因素有关。关于中药,有大量具有抗炎、抗氧化、调节糖脂代谢等多种药理作用的药物及方剂,广泛应用于T2DM及其并发症的治... 详细信息

2型糖尿病(T2DM)的发病机制尚不明确,可能与胰岛素抵抗、炎症反应、氧化应激、脂质代谢异常、肠道菌群失调和遗传等因素有关。关于中药,有大量具有抗炎、抗氧化、调节糖脂代谢等多种药理作用的药物及方剂,广泛应用于T2DM及其并发症的治疗。本文阐述了中药治疗T2DM的主要作用机制及其相关信号通路。

关键词： 2型糖尿病中药胰岛素抵抗信号通路

Bright Prospects for China-South Korea FTA

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今日中国：英文版 2014年第11期63卷 38-40页

作者： yu yingli the Shanghai Institute for International Studies

DURING President Xi Jinping’s state visit to the ROK in July,China and South Korea pledged to conclude negotiations on a free trade agreement(FTA)before the end of this *** China and South Korea established diplomatic relations 22years ago,trade between the two countries has grown at an average yearly rate of 23 *** 2012,bilateral trade reached a new high of US$256.3 billion.

关键词：自由贸易协定中国韩国习近平 FTA

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大型障碍物影响下航向信标敏感区的划设

系统工程与电子技术 2023年第2期45卷 360-372页

作者：倪育德于颖丽刘瑞华秦哲王凯中国民航大学电子信息与自动化学院天津300300 中国民航大学中欧航空工程师学院天津300300

国际民航组织给出了仪表着陆系统航向信标(localizer,LOC)敏感区划设建议,但没有考虑大型障碍物的影响,也没有提供相应理论说明。中国民航正在提升仪表着陆系统的运行等级,必须评估大型建筑物对该敏感区的影响。聚焦机载LOC接收信号的... 详细信息

国际民航组织给出了仪表着陆系统航向信标(localizer,LOC)敏感区划设建议,但没有考虑大型障碍物的影响,也没有提供相应理论说明。中国民航正在提升仪表着陆系统的运行等级,必须评估大型建筑物对该敏感区的影响。聚焦机载LOC接收信号的调制度差(difference in depth of modulation,DDM),分析研究大型障碍物产生的LOC反射信号、边缘绕射信号及尖顶绕射信号对DDM的影响,基于双频20单元LOC阵列天线建立DDM计算模型,仿真分析了铁质和水泥材质大型障碍物在不同位置时对DDM的影响,获得了大型障碍物影响下LOC敏感区,并为国内某条实施III类运行跑道附近的机库改造提供相应建议。

关键词：仪表着陆系统航向信标调制度差一致性几何绕射理论多径干扰

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