检索结果-南通市图书馆

Identification and QTL mapping of Z550, a rice backcrossed inbred line with increased grains per panicle

Journal of Integrative Agriculture 2019年第3期18卷 526-531页

作者： WANG Shi-ming CUI Guo-qing WANG Hui MA Fu-ying XIA Sai-sai LI Yun-feng YANG zheng-lin LING ying-hua ZHANG Chang-wei HE Guang-hua ZHAO Fang-ming Rice Research Institute Academy of Agricultural SciencesSouthwest UniversityChongqing 400715P.R.China

An elite backcrossed inbred line Z550 with increased grains per panicle was identified from advanced backcrosses between Nipponbare and Xihui 18 by simple sequence repeat(SSR) marker-assisted selection(MAS). Z550 carries 13 substitution segments distributed on chromosomes 1, 6, 7, 8, 9, 10, and 12, with an average substitution length of 1.68 Mb. Compared with the Nipponbare parental line, plant height, panicle length, spikelets per panicle, grains per panicle, and grain weight for Z550 were significantly increased. While the grain width of Z550 was significantly narrower, and the seed setting ratio(81.43%) was significantly lower than that of Nipponbare, it is still sufficient for breeding purposes. Quantitative trait loci(QTLs) mapping for important agronomic traits was conducted with the F_2 population derived from Nipponbare crossed with Z550 using the restricted maximum likelihood(REML) method. A total of 16, including 12 previously unreported QTLs were detected, with contribution rates ranging from 1.46 to 10.49%. Grains per panicle was controlled by 8 QTLs, 5 of which increased number of grains whereas 3 decreased it. qGPP-1, with the largest contribution(10.49%), was estimated to increase grains per panicle by 30.67, while q GPP-9, with the minimum contribution rate(2.47%), had an effect of increasing grains per panicle by 15.79. These results will be useful for further development of single segment substitution lines with major QTLs, and for research of their molecular functions via QTL cloning.

关键词： rice backcrossed inbred line yield QTL mapping

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intermolecular Interaction of HMX: an Application of ONIOM Methodology

引用

Chemical Research in Chinese Universities 2004年第5期20卷 602-605页

作者： JUXue-hai BEIFeng-li XIAQi-ying XIAOHe-ming DepartmentofChemistry NanjingUniversityofScienceandTechnologyNanjing210094P.R.China

Ab initio calculations at the B3LYP/3-21G^(**), HF/3-21G>^(**) and ONIOM(HF/3-21G^(**): AM1) levels of the theory in combination with counterpoise procedure for BSSE correction were performed on HMX dimers. There exist two O...H intermolecular contacts and the dispersion forces are dominant in the dimers. The corrected binding energies of the dimer are -15.10 and -17.81 kJ/mol at the HF/3-21G^(**) and \{ONIOM(HF/3-21G^(**): AM1) \}levels, respectively. The calculation by the B3LYP method gives irrational corrected binding energies though it produces similar intermolecular distances as those produced by the HF or \{ONIOM\} method. The geometrical parameters, the contact distances and the binding energies demonstrated, for the first time, the validity of the ONIOM method applied in the calculation of the parameters of intermolecular interactions.

关键词： HMX dimer Intermolecular interaction Ab initio ONIOM methodology

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

PD-L1表达指导的信迪利单抗与帕博利珠单抗联合或不联合含铂双药化疗治疗未经治晚期非小细胞肺癌患者:一项2期随机对照试验(CTONG1901)

引用

Science Bulletin 2024年第4期69卷 535-543页

作者：刘思阳黄婕邓嘉怡徐崇锐严红虹杨明意黎扬斯柯娥娥郑明英王震林嘉欣甘彬张绪超陈华军汪斌超涂海燕杨衿记钟文昭李扬秋周清吴一龙 Department of Hematology The First Affiliated HospitalJinan UniversityGuangzhou 510632China Guangdong Lung Cancer Institute Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080China Chinese Thoracic Oncology Group(CTONG) Guangzhou 510055China Institute of Hematology School of MedicineKey Laboratory for Regenerative Medicine of Ministry of EducationJinan UniversityGuangzhou 510632China

No direct comparison has been performed between different programmed cell death-1(PD-1)inhibitors for first-line treatment in patients with advanced non-small cell lung cancer(NSCLC).The feasibility of using PD-L1-expression-guided immunotherapy remains *** this open-label,phase 2 study(NCT04252365),patients with advanced NSCLC without EGFR or ALK alterations were randomized(1:1)to receive sintilimab or pembrolizumab monotherapy(PD-L1 expression≥50%),or sintilimab or pembrolizumab plus platinum-based chemotherapy(PD-L1 expression<50%).The sample size was calculated by optimal two-stage *** primary endpoint was the objective response rate(ORR).The study included 71 patients(sintilimab arms,n=35;pembrolizumab arms,n=36)and met its primary endpoint,with a confirmed ORR of 51.4%(18/35)in the sintilimab *** confirmed ORR(95%confidence interval)was 46.2%(19.2%,74.9%)and 42.9%(17.7%,71.1%)for patients treated with sintilimab and pembrolizumab monotherapy;and 54.5%(32.2%,75.6%)and 45.4%(24.4%,67.8%)for those treated with sintilimab-and pembrolizumab-based combination *** median progression-free survival was6.9 versus 8.1 months for all sintilimab-treated versus all pembrolizumab-treated patients,respectively,in which it was 7.6 versus 11.0 months in monotherapy and 7.4 versus 7.1 months in combination *** median overall survival was 14.9 versus 21.3 months for all sintilimab-treated versus all pembrolizumab-treated patients,respectively,in which it was 14.9 versus 22.6 months in monotherapy and 14.7 versus 17.3 months in combination ***-related adverse events were consistent with safety outcomes of monotherapy and combination therapy in previous phase III ***,the incidence of rash was higher with sintilimab than pembrolizumab *** is the first prospective phase 2 study to directly compare two anti-PD-1 antibodies as first-line treatment in advanced *** was efficacious and well-tolera

关键词： PD-1 inhibitor Non-small cell lung cancer Pembrolizumab Sintilimab PD-L1 expression

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antitumor effects of different Ganoderma lucidum spore powder in cell-and zebrafish-based bioassays

引用

Journal of Integrative Medicine 2021年第2期19卷 177-184页

作者： Yue-jiao Shi Hua-xian zheng Zhu-ping Hong Han-bo Wang ying Wang ming-yan Li Zhen-hao Li Zhejiang Shouxiangu Pharmaceutical Co. LtdWuyi 321200Zhejiang ProvinceChina Zhejiang Shouxiangu Botanical Drug Institute Co. LtdHangzhou 310012Zhejiang ProvinceChina Zhejiang Engineering Research Center of Rare Medicinal Plants Wuyi 321200Zhejiang ProvinceChina Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310012Zhejiang ProvinceChina

Objective:Ganoderma lucidum spore(GLS)is gaining recognition as a medicinal part of *** and has been reported to possess various pharmacological properties,such as antitumor *** this work,wall-broken GLS powder(BGLSP)and wall-removed GLS powder(RGLSP),two kinds of GLS powder with different manufacturing techniques,were compared in terms of contents of active constituents and in vivo and in vitro antitumor ***:The ultraviolet and visible spectrophotometry method was used to determine the contents of polysaccharides and total triterpenoids in BGLSP and *** individual triterpenoids were further quantified using ultra-high-performance liquid chromatography and quantitative analysis of multicomponents by single *** antitumor effects of BGLSP and RGLSP were evaluated using in vitro cell viability assay against human gastric carcinoma SGC-7901,lung carcinoma A549 and lymphoma Ramos and further validated by in vivo zebrafish xenograft models with transplanted SGC-7901,A549 and Ramos,Results:The results showed that the contents of polysaccharides,total triterpenoids and individual triterpenoids of RGLSP were significantly higher than those of *** both BGLSP and RGLSP inhibited the three tumor cell lines in vitro in a dose-dependent manner,the inhibitory effects of RGLSP were much better than those of *** the in vivo zebra fish assay,RGLSP exhibited more potent inhibitory activities against tumors transpla nted into the zebra fish compared with BGLSP,and the inhibition rates of RGLSP reached approximately 78%,31%and 83%on SGC-7901,A549 and Ramos,***:The results indicated that the antitumor effects of GLS were positively correlated with the contents of the polysaccha rides and triterpenoids and demonstrated that the wall-removing manufacturing technique could significantly improve the levels of active constituents,and thereby enhance the antitumor activity.

关键词： Ganoderma lucidum Tumor Cancer cell Zebrafish Wall-broken Ganoderma lucidum spore powder Wall-removed Ganoderma lucidum spore powder

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pseudo-crown ether having AIE and PET effects from a TPE-CD conjugate for highly selective detection of mercury ions

引用

Chinese Chemical Letters 2022年第3期33卷 1505-1510页

作者： Kai-Ran Zhang ming Hu Jun Luo Fengying Ye Ting-Ting Zhou ying-Xue Yuan Miao-Li Gao Yan-Song zheng Key Laboratory of Material Chemistry for Energy Conversion and Storage Ministry of EducationSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074China Tongji School of Pharmacy Huazhong University of Science and TechnologyWuhan 430030China

A new tetraphenylethylene-cyclodextrin (TPE-CD) conjugate with a linkage composed of long triethylene glycol chain and triazole ring on the CD rim has been designed and synthesized. The TPE-CD conjugate exists in a stretched form in DMSO and enhances its fluorescence after addition of a small amount of water due to aggregation-induced emission (AIE) effect. However, in the presence of a large amount of water, the TPE unit will enter the cyclodextrin cavity to form a folded self-inclusion compound. In the self-inclusion compound, not only nitrogen-containing pseudo-crown ether is formed but also arouses photo-induced electron transfer (PET) process from nitrogen atoms of triazole ring to TPE unit and quenches the fluorescence although more aggregation occurs in more water. This is the first finding that TPE-macrocycle conjugate can form pseudo-crown ether and has both the AIE phenomenon and the PET effect. Interestingly, only mercury ion arouses the fluorescence recover of the self-inclusion compound by entering the pseudo-crown ether cavity and blocking the PET process by binding to the nitrogen atoms, while other tested metal ions almost have no effect on the fluorescence. Therefore, the TPE-CD conjugate can be used for the highly selective fluorescence "Turn-On" detection of Hg^(2+).

关键词： Tetraphenylethylene-cyclodextrin conjugate Aggregation-induced emission Self-inclusion compound Photo-induced electron transfer Mercury ion sensor Highly selective Pseudo-crown ether

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Electrochemically promoted N-heterocyclic carbene polymercatalyzed cycloaddition of aldehyde with isocyanide acetate

引用

Science China Chemistry 2022年第10期65卷 1873-1878页

作者： Chu-Hong Ou ying-ming Pan Hai-Tao Tang State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources School of Chemistry and Pharmaceutical Sciences of Guangxi Normal UniversityGuilin 541004China

N-heterocyclic carbene(NHC) is a potent organic small-molecule ***,its high synthetic price and frequent use in combination with excess oxidants have limited its utilization in industrial *** designed and synthesized a porous organic polymer with NHC as the core structure to solve the above *** catalytic performance of the polymer was tested in this *** polymer can successfully catalyze the cycloaddition reaction of aldehyde and ethyl isocyanoacetate under *** results showed that the polymer catalyst can be recycled and had higher catalytic activity than homogeneous *** developed catalytic system(organic electrochemistry and NHC polymer) solves the existing problems of NHC catalysis and provides a reference for the development of new green catalytic systems.

关键词： NHC catalysis electrochemistry heterogeneous catalysis cycloaddition

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Conductive and corrosion behaviors of silver-doped carbon-coated stainless steel as PEMFC bipolar plates

引用

International Journal of Minerals,Metallurgy and Materials 2016年第7期23卷 844-849页

作者： ming Liu Hong-feng Xu Jie Fu ying Tian College of Environmental and Chemical Engineering Dalian Jiaotong University

Ni–Cr enrichment on stainless steel SS316 L resulting from chemical activation enabled the deposition of carbon by spraying a stable suspension of carbon nanoparticles; trace Ag was deposited in situ to prepare a thin continuous Ag-doped carbon film on a porous carbon-coated SS316 L substrate. The corrosion resistance of this film in 0.5 mol·L^（-1） H_2SO_4 solution containing 5 ppm F- at 80°C was investigated using polarization tests. The results showed that the surface treatment of the SS316 L strongly affected the adhesion of the carbon coating to the stainless steel. Compared to the bare SS316 L, the Ag-doped carbon-coated SS316 L bipolar plate was remarkably more stable in both the anode and cathode environments of proton exchange membrane fuel cell（PEMFC） and the interface contact resistance between the specimen and Toray 060 carbon paper was reduced from 333.0 m？·cm^2 to 21.6 m？·cm^2 at a compaction pressure of 1.2 MPa.

关键词： proton exchange membrane fuel cells bipolar plates stainless steel silver carbon spraying corrosion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Identification of sweet spots in shale-type and siltstone-type“shale oil systems”:A case study of the Chang 7 Member in Ordos Basin

引用

Science China Earth Sciences 2023年第7期66卷 1647-1663页

作者： Songqi PAN Qiulei GUO Caineng ZOU Zhenhua JING ming YUAN ying HE He zheng ying MU Zhi YANG Shixiang LI Xinping ZHOU Songtao WU Hanlin LIU Feng YANG Yuanjia HAN Research Institute of Petroleum Exploration and Development PetroChinaBeijing 100083China State Key Laboratory of Enhanced Oil Recovery Beijing 100083China School of Earth Resources China University of GeosciencesWuhan 430074China Institute of Porous Flow and Fluid University of Chinese Academy of SciencesBeijing 100049China Changqing Oilfield Company PetroChinaXi’an 710018China

Mid-high maturity shale oil is the most realistic field for the scale breakthrough of terrestrial shale oil production in ***,three deficiencies hinder shale oil development in China:heavy oil density,small sweet spot areas,and poor distribution ***,identifying the“sweet spots”in shale oil reservoirs is critical for the efficient exploration and development of terrestrial shale *** study targets the siltstone type(Class-Ⅱshale oil)and pure shale type(Class-Ⅲshale oil)of the Chang 7 Member in the Ordos Basin,and identifies three stratigraphic units,namely the hydrocarbon accumulation unit,hydrocarbon generation unit,and hydrocarbon retention unit,which together constitute the in-source“shale oil system”.The hydrocarbon accumulation unit is mainly siltstone,where the hydrocarbons are migrated from *** has favorable porethroat network connectivity with a pore connectivity ratio of 32–57%,being the siltstone-type sweet *** hydrocarbon generation unit is mainly composed of high-TOC mudstone/shale and is the main contributor to in-source hydrocarbon generation and *** unit has high three-dimensional connectivity(28–30%),as shown by the pore-throat network model,associated with vertical paths for hydrocarbon *** hydrocarbon retention unit is mainly composed of low-TOC mudstone/shale retaining self-generated and migrated *** pore connectivity rate is 17–42%,and the pore-throat network connectivity direction is *** and low-carbon-number hydrocarbons are preferentially trapped or even sealed in small pores of the retention unit,forming the typical mudstone/shale-type sweet *** the process called shale oil intrasource migration,the oil migrates in source rocks causing component fractionation,which allows more shale oil to enrich in the hydrocarbon accumulation and retention units to form sweet spots,compared with the hydrocarbon generation *** migration paths include the one from muds

关键词： Shale oil system Hydrocarbon accumulation unit Hydrocarbon generation unit Hydrocarbon retention unit Differentiated enrichment Sweet spots window Pore-throat network Throat direction

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hot deformation behavior and microstructure evolution of TiC–Al_2O_3/Al composites

引用

Rare Metals 2015年第10期34卷 725-730页

作者： Rui-ying Zhang Zhi-ming Shi Xiu-Mei Zhang School of Materials Science and Engineering Inner Mongolia University of Technology Key Laboratory of Light Metal Materials

Hot compression behavior of TiC–Al2O3/Al composites was studied using the Gleeble-1500 system at a temperature range of 300–550 °C and at strain rate range of 0.01–10.00 s-1. The associated structural changes were studied by TEM observations. The results show that stress level decreases with deformation temperature increasing and strain rate decreasing, which can be represented by a Zener–Hollomon parameter in an exponent-type equation with hot deformation activation energy Q of 172.56 kJ·*** recovery occurs easily when strain rates are less than 10.00 s-1. Dynamic recrystallization can occur at strain rate of 10.00 s-1.

关键词： TiC–Al2O3/Al composites Hot deformation Flow stres

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Seeing time-reversal transmission characteristics through kinetic anti-ferromagnetic Ising chain

引用

Chinese Physics B 2012年第2期21卷 419-424页

作者： Chen ying-ming Wang Bing-Zhong Institute of Applied Physics University of Electronic Science and Technology of ChinaChengdu 610054China School of Physics and Electronic Information Huaibei Normal UniversityHuaibei 235000China

As an example of our new approach to complex near-field （NF） scattering of electromagnetic waves, the timereversal （TR） transmission process on an NF current-element array is mapped to the statistical process on a kinetic Ising transmission chain. Equilibrium statistical mechanics and non-equilibrium Monte Carlo （MC） dynamics help us to find signal jamming, aging, annihilating, creating, and TR symmetry breaking on the chain with inevitable background noises; and these results are general in NF systems where complex electromagnetic scattering arises.

关键词： time-reversal near-field scattering symmetry breaking temporal focusing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：