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Association of prealbumin with short-term and long-term outcomes in patients with acute ST-segment elevation myocardial infarction

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Journal of Geriatric Cardiology 2024年第4期21卷 421-430页

作者： Jing TAN Jin SI Ke-Ling XIAO ying-hua zhang Qi hua Jing LI Department of Cardiology Xuanwu Hospital Capital Medical UniversityBeijingChina Department of Geriatric Medicine Xuanwu Hospital Capital Medical UniversityNational Clinical Research Center for Geriatric DiseasesBeijingChina

BACKGROUND Prealbumin is considered to be a useful indicator of nutritional status. Furthermore, it has been found to be associated with severities and prognosis of a range of diseases. However, limited data on the association of baseline prealbumin level with outcomes of patients with acute ST-segment elevation myocardial infarction(STEMI) are *** We analyzed 2313 patients admitted for acute STEMI between October 2013 and December 2020. In-hospital outcomes and mortality during the 49 months(interquartile range: 26–73 months) follow-up period were compared between patients with the low prealbumin level(< 170 mg/L) and those with the high prealbumin level(≥ 170 mg/L).RESULTS A total of 114 patients(4.9%) died during hospitalization. After propensity score matching, patients with the low prealbumin level than those with the high prealbumin level experienced higher incidences of heart failure with Killip class Ⅲ(9.9%vs. 4.4%, P = 0.034), cardiovascular death(8.4% vs. 3.4%, P = 0.035) and the composite of major adverse cardiovascular events(19.2%vs. 10.3%, P = 0.012). Multivariate logistic regression analysis identified that the low prealbumin level(< 170 mg/L) was an independent predictor of in-hospital major adverse cardiovascular events(odds ratio = 1.918, 95% CI: 1.250–2.942, P = 0.003). The cutoff value of prealbumin level for predicting in-hospital death was 170 mg/L(area under the curve = 0.703, 95% CI: 0.651–0.754, P< 0.001;sensitivity = 0.544, specificity = 0.794). However, after multivariate adjustment of possible confounders, baseline prealbumin level(170 mg/L) was no longer independently associated with 49-month cardiovascular death. After propensity score matching, Kaplan-Meier survival curves revealed consistent *** Decreased prealbumin level closely related to unfavorable short-term outcomes. However, after multivariate adjustment and controlling for baseline differences, baseline prealbumin level was not independently assoc

关键词： patients admitted infarction

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Indoor channel characteristics based on wideband MIMO measurements at 5.25 GHz

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The Journal of China Universities of Posts and Telecommunications 2008年第4期15卷 46-50页

作者： GAO Xin-ying zhang Jian-hua zhang Ping Key Laboratory of Universal Wireless Communications Ministry of Education Wireless Technology Innovation Institute Beijing University of Posts and Telecommunications Beijing 100876 China

Extensive indoor channel measurements were conducted in Beijing with wideband multiple-input multiple-output （MIMO） sounder at 5.25 GHz. Both line-of-sight （LOS） and non-line-of-sight （NLOS） propagation were measured in the indoor office and hotspot scenarios. On the basis of measured data, statistical channel characteristics are presented in this article, including the empirical path loss （PL） models, three excess delay parameters, circular azimuth spread （CAS）, and circular elevation spread （CES）. Comparative analysis of different propagation mechanisms in two scenarios is conducted. These values are significant for indoor coverage and technical research of MIMO and orthogonal frequency division multiplexing （OFDM） for the international mobile telecommunications-advanced （IMT-Advanced） system.

关键词： channel measurement wideband MIMO path loss excess delay circular azimuth spread circular elevation spread IMT-Advanced

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Euclidean distance harmonic method for establishing theoretical MAPK/Erk signaling pathway in treated breast cancer line MCF-7

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The Journal of China Universities of Posts and Telecommunications 2007年第1期14卷 80-84页

作者： zhang Hong-xin LU ying-hua zhang Jin-ling School of Electronic Engineering Beijing University of Posts and Telecommunications Beijing 100876 China

Hierarchical clustering algorithms, such as Pearson＇s correlation, Euclidean distance, Euclidean distance harmonic, Spearman rank correlation, Kendall＇s tau, and City-block distance, were used to find the best way to establish theoretical MAPK/Erk signaling pathway on the basis of breast cancer line MCF-7 gene expressions. The algorithm constructs a hierarchy from top to bottom on the basis of a self-organizing tree. It dynamically finds the number of clusters at each level. It was found that only Euclidean distance harmonic is fit for the analysis of the cascade composed from a RAF1 （c-Raf）, a MKNK1, a MAPKK （MEK1/2） to MAPK （Erk） in breast cancer line MCF-7. The result is consistent with the biological experimental MAP/Erk signaling pathway, and the theoretical MAPK/Erk signaling pathway on breast cancer line MCF-7 is set up.

关键词： hierarchical clustering signaling pathway,Euclidean distance harmonic

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Finite Time Convergent Wavelet Neural Network Sliding Mode Control Guidance Law with Impact Angle Constraint

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International Journal of Automation and computing 2015年第6期12卷 588-599页

作者： Qing-Chun Li Wen-Sheng zhang Gang Han ying-hua zhang Institute of Automation Chinese Academy of Sciences

This paper presents a novel guidance law to intercept non-maneuvering targets with impact angle and lateral acceleration command constraints. Firstly, we formulate the impact angle control to track the desired line-of-sight(LOS) angle, which is achieved by selecting the missile s lateral acceleration to enforce the sliding mode on a sliding surface at impact time. Secondly, we use the Lyapunov stability theory to prove the stability and finite time convergence of the proposed nonlinear sliding surface. Thirdly, we introduce the wavelet neural network(WNN) to adaptively update the additional control command and reduce the high-frequency chattering of sliding mode control(SMC). The proposed guidance law, denoted WNNSMC guidance law with impact angle constraint,combines the SMC methodology with WNN to improve the robustness and reduce the chattering of the system. Finally, numerical simulations are performed to demonstrate the validity and effectiveness of the WNNSMC guidance law.

关键词： Guidance law sliding mode control wavelet neural n

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Effect of Atmospheric Interfering Absorption on Measurement of BTX by DOAS

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Chinese Journal of Chemical Physics 2008年第3期21卷 202-210页

作者： Fu-min Peng Pin-hua Xie Hai-yang Li ying-hua zhang Jun-de Wang Wen-qing Liu Key Laboratory of Environmental Optical and Technology Anhui Institute of Optics and Fine Mechanics Chinese Academy of Sciences Hefei 230031 China College of Chemistry and Chemical Engineering Anhui University Hefei 230039 China Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China

It was reported on the elimination of interfering absorption of BTX. the absorption of O2 includes different absorption bands, which change differently when the partial pressure of oxygen is varied. These cause the nonlinear absorption of O2 and the observed band shape to vary with the column density of O2. The absorption ratios of molecular absorption in each of the Herzberg bands and dimer absorptions, as well as the contribution to the correction error of molecular absorption, are studied based on the characteristic of these absorption bands. The optimized way to eliminate the interfering absorption is obtained in the end and the effectiveness of using interpolation proposed by Volkamer et al. to remove O2 absorption is proved again. As to O2 and SO2, the effect of the thermal effect of characteristic spectra on the elimination error of their absorption is studied. Solutions to these problems are discussed and demonstrated together with methods to optimize the interpolation of spectra. As a sample application, differential optical absorption spectroscopy （DOAS） measurements of BTX are carried out. Results show a low detection limit and the good correlation with point instruments are achieved. All these prove the feasibility of using spectral interpolation to improve the accuracy of DOAS measurements of aromatic hydrocarbons for practical purposes.

关键词： Differential optical absorption spectroscopy BTX Herzberg band O2 dimer

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Incidence,predictors and prognosis of acute kidney injury in acute ST-segment elevation myocardial infarction patients undergoing emergent coronary angiography/primary percutaneous coronary intervention

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Journal of Geriatric Cardiology 2023年第2期20卷 139-149页

作者： Jing TAN ying-hua zhang Jin SI Ke-Ling XIAO Qi hua Jing LI Department of Cardiology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Geriatric Medicine Xuanwu HospitalCapital Medical UniversityNational Clinical Research Center for Geriatric DiseasesBeijingChina

BACKGROUND Acute kidney injury(AKI) after coronary angiography(CAG) and primary percutaneous coronary intervention(PPCI) is frequently observed, and often interpreted as contrast induced-AKI. This study aimed to investigate the incidence, predictors and outcomes of AKI in acute ST-segment elevation myocardial infarction(STEMI) patients undergoing emergent CAG/PPCI using the control group of STEMI patients who were not exposed to contrast agents within the first 72 *** We performed a retrospective analysis of 1670 STEMI patients. Of them, 673 patients underwent emergent CAG/PPCI, and 997 patients treated with thrombolysis or no reperfusion therapy who were not exposed to contrast material during the first 72 h. AKI was defined as an increase of serum creatinine ≥ 44.2 mmol/L or ≥ 25% from baseline within 72 h. Patents were then followed up for the occurrence of all-cause mortality for 40 months(interquartile range: 24–55 months).RESULTS After propensity score matching, 505 pairs of patients were matched. Overall, the incidence of AKI was 27.4%, and AKI rates were not significantly different in patients with and without emergent CAG/PPCI procedure(27.5% vs. 27.3%, P = 0.944). Multivariate logistic regression analysis identified that the independent predictors of AKI were female, elevated interleukin-6 level,decreased lymphocyte count, left ventricular ejection fraction < 50% and use of diuretics in patients with emergent CAG/PPCI. Patients with AKI than those without AKI experienced higher incidence of acute heart failure with Killip class Ⅲ(9.4% vs. 3.3%, P =0.005;15.2% vs. 6.8%, P = 0.003, respectively) and mortality(5.8% vs. 1.4%, P = 0.014;12.3% vs. 4.6%, P = 0.002, respectively) in patients with and without emergent CAG/PPCI. Multivariate Cox regression analysis confirmed that AKI was independently associated with long-term mortality rate at 40 months follow-up in patients with and without emergent CAG/PPCI(HR = 1.867, 95% CI:1.086–3.210, P = 0.024;HR = 1.7

关键词： patients coronary infarction

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Compute extremely low-frequency electromagnetic field exposure by 3-D impendance method

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The Journal of China Universities of Posts and Telecommunications 2007年第3期14卷 113-116页

作者： HAN Yu-nan LV ying-hua zhang Hong-xin Beijing University of Posts and Telecommunications Beijing 100876 ChinaAerospace Science and Technology Group Beijng 100076 China

A 3-D impedance method has been introduced to compute the electric currents induced in a human body exposed to extremely low-frequency electromagnetic field. The 3-D impedance method has been deduced from Maxwell equations and is put into the computation and simulation effectively to the visible human body model, which has 196×114×626 cells and more than 40 types of tissues. As the result, two representative cases are investigated. One is exposure of the human body to 100 μT （1 000 mG）, the limit recommended by the International Commission on Non-Ionizing Radiation Protection for the public and the other one is the exposure of human body to 0.4 laT （4 mG）, the level at which a statistical link appears with a doubled risk of development of childhood leukaemia. The distribution of induced current density can be obtained and the maximum of induced current are found to be 16 mA/m^2 and 0.07 mA/m^2.

关键词： 3-D impedance method induced current magnetic flux density visible human body model extremely low frequency (ELF)

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Nitrate Effect on Rice Growth and Nitrogen Absorption and Assimilation at Different Growth Stages

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Pedosphere 2006年第6期16卷 707-717页

作者： DUAN ying-hua zhang Ya-Li SHEN Qi-Rong WANG Song-Wei College of Resources and Environmental Sciences Nanjing Agricultural University Nanjing 210095 China

The effect of nitrate （NO3^-） on rice （Oryza sativa L.） growth as well as N absorption and assimilation during different growth stages was examined using three typical rice cultivars. Dry weight, yield, N uptake, nitrate reductase activity （NRA） in leaves, and glutamine synthetase activity （GSA） in roots and leaves during their entire growth periods, as well as the kinetic parameters of ammonium （NH4^＋） uptake at the seedling stage, were measured with solution culture experiments. Results indicated that addition of NH4^＋-N and NO3^-N at a ratio of 75：25 （NH4^＋＋NO3^- treatment） when compared with that of NH4^＋-N alone （NH4^＋ treatment） increased the dry weight of ‘Nanguang＇ cultivar by 30% and ‘Yunjing 38＇ cultivar by 31%, and also increased their grain yield by 21% and 17%, respectively. For the four growth stages, the total N accumulation in plants increased by an average of 36% for ‘Nanguang＇ and 31% for ‘Yunjing 38＇, whereas the increasing effect of NO3^- in the ‘4007＇ cultivar was only found at the seedling stage, in the NH4^＋＋NO3^- treatment compared to the NH4^＋ treatment, NRA in the leaves increased by 2.09 folds, and GSA increased by 92% in the roots and 52% in the leaves of the three cultivars. NO3^- supply increased the maximum uptake rate （Vmax） in the ‘Nanguang＇ and ‘Yunjing 38＇ cultivars, reflecting that the NO3^- itself, not the increasing N concentration, increased the uptake rate of NH4^＋ by rice. There was no effect on the apparent Michaelis-Menten constant （Kin） of the three cultivars. Thus, some replacement of NH4^＋ with NO3^-could greatly improve the growth of rice plants, mainly on account of the increased uptake of NH4^＋ promoted by NO3^-, and future studies should focus on the molecular mechanism of the increased uptake of NH4^＋ by NO3^-.

关键词： growth stages N absorption and assimilation nitrate N uptake rice

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Higgs and Bottom Quarks Associated Production at High Energy Colliders in the Littlest Higgs Model with T-Parity

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Communications in Theoretical Physics 2018年第3期69卷 297-302页

作者： Biao-Feng Hou hua-ying zhang Heng-Heng Bi College of Physics and Materials Science Henan Normal University Xinxiang 453007 China

In the littlest Higgs Model with T-parity,we discuss the Higgs production in association with bottom quarks at the LHC and future electron-positron *** calculate the cross sections of production channels pp→bb H,bb→H and bg→b H at 14 Te V LHC and the cross sections of production channel e^+e^-→bb H in(un)polarized beams at the lowest *** order to investigate the observability,we display some typical final state distributions in the Higgs to diphoton channel.

关键词： Higgs boson bottom quark littlest Higgs model with T-parity

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SAW chirp Fourier transform for MB-OFDM UWB receiver

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The Journal of China Universities of Posts and Telecommunications 2006年第3期13卷 1-4页

作者： HE Peng-fei LUE ying-hua zhang Hong-xin WANG Ye-qiu XU Yong Institute of Telecommunication and Network Technology Beijing University of Posts and Telecommunications Beijing 100876 China

In the conventional multiband orthogonal frequency division multiplexing ultra wideband （MB-OFDM UWB ） receiver, the fast Fourier transform （FFT） algorithm is realized by the expensive and power-consuming digital signal processor （DSP） chips. In this article, the lower power, lower cost, and lower complexity real-time analog surface acoustic wave （SAW） chirp Fourier transform devices were used to replace the DSP part. A MB-OFDM UWB receiver based on the M-C-M SAW chirp Fourier transform was presented, and the step of signal transformation from input signals was also depicted. The simulation results show that the proposed receiver provides similar bit error performance compared to the fully digital receiver when used in the channel environments proposed by the IEEE 802.15SG3a.

关键词： MB-OFDM UWB SAW chirp Fourier transform

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