检索结果-南通市图书馆

2024社会发展与科技创新交流会

作者： ying Zheng Si-qin Huang Yijia Gao Shanghai University of Engineering and Science Guangxi Normal University

"Lifelong learning" has become an international trend, and the kernel emphasizes that everyone can learn,everywhere can learn, and all the time can learn. Museums are excellent places for lifelong learning for all social classes and all kinds of people. The concept of lifelong learning in museums in China has been around for a long time, but no systematic knowledge has been formed in considering the sustainability strategies for special groups to participate in lifelong learning. The article takes museums and lifelong learning for special groups as the entry point, and selects Italy as a mirror case to explore the strategies and inspirations of international advanced museums in serving lifelong learning for special groups. The study summarizes four strategies: accessibility in spatial area design, diversity in knowledge and information acquisition, inclusiveness and empathy in educational activity design, and sustainable development of learning ability and awareness. Through the strategies, specific cases are introduced to introduce the concrete practices of Italian museums, and it is proposed that the construction of barrier-free museums should be promoted, diversified and targeted educational activities should be customized, and inclusive culture and cultivation of lifelong learning should be advocated. Inclusive culture and lifelong learning culture should be fostered to promote the construction of a universal friendly learning society, which calls for the museums in China to take the initiative to assume the responsibility and mission of serving the construction of a universal friendly learning society.

关键词： Italy Lifelong Learning Museum Education Special Groups

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Chinese Journal of Integrative Medicine 2024年第8期30卷 684-691页

作者： CAO Wei WANG Lu HOU Ting-hui SHI Yun-zhou ZHENG Qian-hua ZHENG Hui ZOU Zi-hao qin Di YANG Qian CHEN Si-jue WANG Hai-yan XIAO Xian-jun LI ying Department of Acupuncture and Moxibustion Chengdu University of Traditional Chinese MedicineChengdu610000China Acupuncture and Moxibustion School of Health Preservation and Rehabilitation Chengdu University of Traditional Chinese MedicineChengdu610000China

Objective: To explore the demographic and disease-related factors associated with acupuncture response in patients with chronic tension-type headache(CTTH). Methods: Using data from the randomized clinical trial(218 cases) consisting of 4 weeks of baseline assessment, 8 weeks of treatment, and 24 weeks of follow-up, participants were regrouped into responders(at least a 50% reduction in monthly headache days at week 16 compared with baseline) and non-responders. Twenty-three demographic and disease-related factors associated with acupuncture response in 183 participants were analyzed by multivariable logistic regression. Results: One hundred and nineteen(65.0%) participants were classified as responders. Four factors were significantly independently associated with acupuncture response, including treatment assignment, headache intensity at baseline, and 2 domains [general health(GH) and social functioning(SF)] from the 36-Item Short Form Health Survey quality of life questionnaire. Treatment assignment was associated with nonresponse: participants receiving true acupuncture were 3-time more likely to achieve a CTTH response than those receiving superficial acupuncture [odds ratio(OR) 0.322, 95% confidence interval(CI) 0.162 to 0.625, P=0.001]. Compared with patients with mild-intensity headache, patients with moderate-intensity headache were twice as likely to respond to acupuncture(OR 2.001, 95% CI 1.020 to 4.011, P=0.046). The likelihood of non-response increased by 4.5% with each unit increase in the GH grade(OR 0.955, 95% CI 0.917 to 0.993, P=0.024) while decreased by 3.8% with each unit increase in the SF grade(OR 1.038, 95% CI 1.009 to 1.069, P=0.011). Conclusions: Greater headache intensity, lower GH score, and higher SF score were associated with better acupuncture responses in CTTH patients. These 3 factors require independent validation as predictors of acupuncture effectiveness in CTTH.

关键词： acupuncture chronic tension-type headache logistic regression quality of life Chinese medicine

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终身收支视角下长期护理保险的再分配效应——基于性别和参保类型的考察

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保险研究 2024年第1期 59-71页

作者：肖颖朱勤复旦大学社会发展与公共政策学院复旦大学老龄研究院

互助共济是社会保障制度的本质特征,考察其再分配效应是评价一项社会保障制度互助共济功能的有效方法之一。本文从终身收支的视角出发,构建了健康保险精算模型,测算不同性别和参保类型群体的缴费回报率,以比较长期护理保险试点城市制度... 详细信息

互助共济是社会保障制度的本质特征,考察其再分配效应是评价一项社会保障制度互助共济功能的有效方法之一。本文从终身收支的视角出发,构建了健康保险精算模型,测算不同性别和参保类型群体的缴费回报率,以比较长期护理保险试点城市制度方案的再分配效应。研究结果表明:首先,由于女性失能持续时间更长、工资水平更低,女性参保者的缴费回报率高于男性,从而呈现出“男性补贴女性”的再分配效应。其次,城居保参保者的缴费回报率高于城职保参保者,呈现出“职工补贴居民”的再分配效应;“比例筹资”模式对不同参保类型群体的再分配效应比“定额筹资”模式更强。第三,相比于城职保参保者,60岁城居保参保者的预期余寿更短,但失能持续时间却更长;60岁男性的预期余寿和失能持续时间均比女性更短。本文建议,提高长护险制度统筹层次,推行比例筹资和待遇均等相结合的模式,形成“量能缴费”和“按需保障”的制度特征;同时,探索和发展农村居民更可及的待遇给付方式,以促进群体间的照护保障公平。

关键词：长期护理保险健康保险精算模型缴费回报率再分配效应

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Do smart city policies improve energy efficiency?Evidence from China

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Chinese Journal of Population,Resources and Environment 2024年第2期22卷 185-193页

作者： Zhilong qin Haoming Yang Lei Shi Ouyang ying Wenhan Liu Institute of Western China Economic Research Southwestern University of Finance and EconomicsChengdu 611130China School of Law Southwestern University of Finance and EconomicsChengdu 611130China School of Business The University of QueenslandQueensland 4072Australia West China School of Medicine West China Hospital of Sichuan UniversityChengdu 610041China Business School Chengdu UniversityChengdu 610106China

To address air pollution and offer a convenient and comfortable living environment,the Chinese government launched a smart city pilot(SCP)project in 2012,accompanied by a comprehensive set of environmental and energy-related laws and *** academic interest in smart cities has surged,there remains a notable gap in empirical research exploring the economic,environmental,and energy effects of such *** 232 prefecture-level cities from 2003 to 2017 as research subjects,this study measures energy effi‐ciency by using energy consumption per unit of GDP and adopts a difference-in-differences(DID)analysis to investigate the impact of SCPs on energy *** empirical results indicate that SCPs improved energy efficiency by promoting urban technological innovation capabilities and green total factor productivity,and this effect was more pronounced in cities that were more dependent on traditional fossil fuel energy sources and had more developed fiscal and financial *** the impact of smart city construction on energy utilization efficiency in developing countries,such as China,is not only significantly enlightening for China’s green and low-carbon transition but also provides reference opinions for constructing smart cities and the path to enhancing energy efficiency in other developing *** findings provide valuable insights into the global development of smart cities,urban sustainability,and high-quality economic growth.

关键词： Smart city project Energy efficiency Legislation on environment and energy Technological innovation capabilities Green total factor productivity Difference-in-differences

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Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patients

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2673-2682页

作者： Huang Chen Rui-ying Jiang Zhan Hua Xiao-Wei Wang Xiao-Li Shi Ye Wang Qian-Qian feng Jie Luo Wu Ning Yan-fen Shi Da-Kui Zhang Bei Wang Jian-Zheng Jie Ding-Rong Zhong Department of Pathology China-Japan Friendship HospitalBeijing 100029China Department of Gastrointestinal Surgery China-Japan Friendship HospitalBeijing 100029China Department of Scientific Research GeneisBeijing 100012China

BACKGROUND RAS,BRAF,and mismatch repair(MMR)/microsatellite instability(MSI)are crucial biomarkers recommended by clinical practice guidelines for colorectal cancer(CRC).However,their characteristics and influencing factors in Chinese patients have not been thoroughly *** To analyze the clinicopathological features of KRAS,NRAS,BRAF,and PIK3CA mutations and the DNA MMR status in *** We enrolled 2271 Chinese CRC patients at the China-Japan Friendship *** proteins were tested using immunohistochemical analysis,and the KRAS/NRAS/BRAF/PIK3CA mutations were determined using quantitative polymerase chain *** status was determined using an MSI detection *** analyses were conducted using SPSS software and logistic *** The KRAS,NRAS,BRAF,and PIK3CA mutations were detected in 44.6%,3.4%,3.7%,and 3.9% of CRC patients,*** mutations were more likely to occur in patients with moderate-to-high *** mutations were more likely to occur in patients with right-sided CRC,poorly differentiated,or no perineural *** MMR(dMMR)was detected in 7.9% of all patients and 16.8% of those with mucinous ***,NRAS,BRAF,and PIK3CA mutations were detected in 29.6%,1.1%,8.1%,and 22.3% of patients with dMMR,*** dMMR was more likely to occur in patients with a family history of CRC,agedying key influencing factors,with implications for clinical management of CRC.

关键词： Colorectal cancer Deficient mismatch repair Microsatellite instability Gene mutation Comprehensive analysis

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TCERG1L hypermethylation is a risk factor of diabetic retinopathy in Chinese children with type 1 diabetes

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 537-544页

作者： Yu Qian ying Xiao Qiu-Rong Lin Zhao-Yu Xiang Li-Pu Cui Jia-Qi Sun Si-Cong Li Xin-Ran qin Hai-Dong Zou Chen-Hao Yang Pei-Yao Jin Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai First People’s HospitalShanghai 200080China Shanghai Eye Diseases Prevention&Treatment Center Shanghai Eye HospitalShanghai 200040China National Clinical Research Center for Eye Diseases Shanghai Clinical Research Center for Eye DiseasesShanghai Key Clinical SpecialtyShanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghai 200080China Department of Ophthalmology Children’s Hospital of Fudan UniversityShanghai 201102China

●AIM:To identify the differential methylation sites(DMS)and their according genes associated with diabetic retinopathy(DR)development in type 1 diabetes(T1DM)children.●METHODS:This study consists of two surveys.A total of 40 T1DM children was included in the first *** no participant has DR,retina thinning was used as a surrogate indicator for *** lowest 25%participants with the thinnest macular retinal thickness were included into the case group,and the others were *** DNA methylation status was assessed by the Illumina methylation 850K array BeadChip assay,and compared between the case and control *** DMS with a potential role in diabetes were *** second survey included 27 T1DM children,among which four had *** methylation patterns of the four DMS identified by 850K were compared between participants with and without DR by pyrosequencing.●RESULTS:In the first survey,the 850K array revealed 751 sites significantly and differentially methylated in the case group comparing with the controls(|Δβ|>0.1 and Adj.P0.05)between participants with and without DR.●CONCLUSION:The hypermethylation of the TCERG1L gene is a risk factor for DR development in Chinese children with T1DM.

关键词： DNA methylation 850K array pyrosequencing diabetic retinopathy type 1 diabetes children

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基于行波理论的桁架结构传感器优化布设方法研究

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工程力学 2024年第11期41卷 168-178页

作者：李英民秦阳刘纲山地城镇建设与新技术教育部重点实验室(重庆大学) 重庆400044 重庆大学土木工程学院重庆400045

针对桁架结构传感器优化布设问题,根据行波在桁架结构中的传播特性,以损伤敏感程度最大化为目标,引用图论,并结合行波动力学,提出基于行波的传感器优化布设方法。将桁架的杆件、节点与图论的边、节点建立映射关系,对图论中的广度搜索法... 详细信息

针对桁架结构传感器优化布设问题,根据行波在桁架结构中的传播特性,以损伤敏感程度最大化为目标,引用图论,并结合行波动力学,提出基于行波的传感器优化布设方法。将桁架的杆件、节点与图论的边、节点建立映射关系,对图论中的广度搜索法进行改进,以考虑行波在桁架结构中沿节点散射和反射的特点,获得行波在桁架结构中的传播路径。通过行波动力学分析,计算各类节点连接形式的行波传递系数,进而与传播路径相结合求得相同时间内所有节点对行波所致振动的敏感系数。基于敏感系数求取敏感总值矩阵,找出对各杆件最为敏感的激励点和传感器布置点。仿真模型和实验桁架结果表明,所提方法所得传感器布置位置对损伤最为敏感,为大型桁架结构传感器优化布设提供了新的方法支撑。

关键词：传感器优化布置桁架结构图论损伤敏感度行波

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Exploration of pathogenic microorganism within the small intestine of necrotizing enterocolitis

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World Journal of Pediatrics 2024年第2期20卷 165-172页

作者： Yan Wang Kun Jiang Qiao Xia Xia Kang Shan Wang Ji-Hong Yu Wen-feng Ni Xiao-qin Qi ying-Na Zhang Jin-Bao Han Gang Liu Lei Hou Zhi-Chun feng Liu-Ming Huang Clinical Biobank Center Medical Innovation Research Division of ChinesePLA General HospitalBeijingChina Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Senior Department of Pediatrics The Seventh Medical Center of PLA General HospitalBeijing 100700China Department of Neurology The First Medical CenterChinese PLA General HospitalBeijing 100853China Department of Emergency Center National Center for Children's HealthBeijing Children's HospitalCapital Medical UniversityBeijing 100045China

Background Necrotizing enterocolitis(NEC)is the most common severe gastrointestinal emergency in *** designed this study to identify the pathogenic microorganisms of NEC in the microbiota of the small intestine of *** Using the 16S ribosomal DNA(rDNA)sequencing method,we compared and analyzed the structure and diversity of microbiotas in the intestinal feces of different groups of neonates:patients undergoing jejunostomy to treat NEC(NP group),neonates undergoing jejunostomy to treat other conditions(NN group),and neonates with NEC undergoing conservative treatment(NC group).We took intestinal feces and saliva samples from patients at different time *** The beta diversities of the NP,NN,and NC groups were all *** comparing the beta diversities between different time points in the NP group,we found similar beta diversities at time points El to E3 but significant differences between the E2-E3 and E4 time points:the abundances of Klebsiella and Enterococcus(Proteobacteria)were higher at the E1-E3 time points;the abundance of Escherichia-Shigella(Proteobacteria)increased at the E2 time point,and the abundance of Klebsiella decreased significantly,whereas that of Streptococcus increased significantly at the E4 time *** Our results suggest that the pathological changes of intestinal necrosis in the small intestine of infants with NEC are not directly caused by excessive proliferation of pathogenic bacteria in the small *** sources of microbiota in the small intestine of neonates,especially in premature infants,may be affected by multiple factors.

关键词： Microbiota Necrotizing enterocolitis-Small intestine 16S rDNA

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早产儿语言发展的影响因素及其干预对策

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生物化学与生物物理进展 2024年第6期51卷 1292-1304页

作者：洪恬张琴芬范娇娇上海交通大学人文学院上海200030 南通大学附属常州儿童医院儿童健康研究中心常州213003

早产儿的语言发展受到多种因素的影响,可能导致他们在词汇、语法、语音等方面出现发展滞后或障碍。本文首先简述了影响早产儿语言发展的生物学和环境因素的研究进展,其中生物学因素包括早产程度、体重和性别、新生儿发病率和疾病严重程... 详细信息

早产儿的语言发展受到多种因素的影响,可能导致他们在词汇、语法、语音等方面出现发展滞后或障碍。本文首先简述了影响早产儿语言发展的生物学和环境因素的研究进展,其中生物学因素包括早产程度、体重和性别、新生儿发病率和疾病严重程度等,环境因素则包括新生儿重症监护室的环境、家庭中的语言环境和社会因素等。在明确这些影响因素的基础上,本文强调了早期评估和早期干预是优化早产儿语言发育效果的关键步骤,并分析了具体的干预对策,例如生理和神经干预、优化新生儿重症监护室(NICU)环境、增强家庭语言互动、多学科合作和社会支持等。此综述旨在探讨影响早产儿语言发展的各种因素,并总结出有效的早期干预措施,为其提供更为全面的语言发展支持。

关键词：早产儿语言发展生物和环境因素早期干预

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基于专利引用的通信芯片产业创新网络韧性研究

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软科学 2024年第8期38卷 94-104页

作者：周霞于娱施琴芬河海大学商学院南京211100 南京审计大学商学院南京211815 苏州科技大学商学院江苏苏州215009

基于2000—2021年全球通信芯片专利引用数据,构建产业创新网络,从静态和动态两个方面对不同技术发展阶段下的网络韧性进行测度。结果表明:(1)全球通信芯片产业创新网络具有无标度性和异质性特征,2000—2021年,网络韧性呈现“正—正—负... 详细信息

基于2000—2021年全球通信芯片专利引用数据,构建产业创新网络,从静态和动态两个方面对不同技术发展阶段下的网络韧性进行测度。结果表明:(1)全球通信芯片产业创新网络具有无标度性和异质性特征,2000—2021年,网络韧性呈现“正—正—负”的演化趋势。(2)不同技术发展阶段中,美国企业节点失效始终使得网络综合韧性值居于最低水平;韩国、中国内地和中国台湾三地企业2008年后对网络韧性的影响力愈发凸显。(3)网络对随机扰动表现出更强韧性,对有针对性的蓄意攻击更为敏感。

关键词：芯片产业创新网络静态韧性动态韧性专利引用

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