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Straw addition increases enzyme activities and microbial carbon metabolism activities in bauxite residue

Journal of Environmental Sciences 2024年第1期135卷 332-344页

作者： Hao Wu wei Sun Feng Zhu Yifan Jiang Shiwei Huang Johnvie Goloran Shengguo xue School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China School of Metallurgy and Environment Central South UniversityChangsha 410083China School of Environment and Science Griffith UniversityBrisbaneQLD 4072Australia

Recovery of microbial functions is one of the critical processes in the nutrient cycling of bauxite residue for improving *** is considered to be effective to increase microbial diversity and drive the development of the microbial community,but its effect on microbial carbon metabolism has not been *** present study evaluated the effects of phosphogypsum(PG),straw(SF)and phosphogypsum plus straw(PGSF)on physicochemical properties,enzyme activities,and microbial carbon metabolism activities in bauxite *** 180 days incubation,PG,SF and PGSF treatment significantly reduced the residue pH from 10.85 to 8.64,9.39 and 8.06,*** to CK treatment,SF treatment significantly increased the content of total organic carbon(TOC)and organic carbon fractions(DOC,MBC,EOC,and POC).In addition,straw addition significantly increased glucosidase,cellulose,urease,and alkaline phosphatase by 7.2-9.1 times,5.8-7.1 times,11.1-12.5 times,and 1.1-2.2 times,*** Biolog results showed that straw addition significantly increased microbial metabolic activity(AWCD)and diversity in bauxite *** analysis indicated total nitrogen(TN)and carbon fractions(POC,MBC and DOC)were the most important environmental factors affecting microbial metabolic activity and diversity in bauxite *** findings provided us with a biogeochemical perspective to reveal soil formation in bauxite residue and suggested that nutrient supplement and regulation of salinity-alkalinity benefit the establishment of microbial communities and functions in bauxite residue.

关键词： Bauxite residue Labile organic carbon fractions Enzyme activities Community-level physiological profiles Soil formation in bauxite residue

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Elevation response of above-ground net primary productivity for Picea crassifolia to climate change in Qilian Mountains of Northwest China based on tree rings

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Journal of Geographical Sciences 2024年第1期34卷 146-164页

作者： WU Xuan JIAO Liang DU Dashi xue Ruhong wei Mengyuan ZHANG Peng College of Geography and Environment Science Northwest Normal UniversityLanzhou 730070China Key Laboratory of Resource Environment and Sustainable Development of Oasis Northwest Normal UniversityLanzhou 730070China

Current ecosystem models used to simulate global terrestrial carbon balance generally suggest that terrestrial landscapes are stable and mature,but terrestrial net primary productivity(NPP)data estimated without accounting for disturbances in species composition,environment,structure,and ecological characteristics will reduce the accuracy of the global carbon ***,the steady-state assumption and neglect of elevation-related changes in forest NPP is a *** Qilian Mountains are located in continental climate zone,and vegetation is highly sensitive to climate *** quantified aboveground biomass(AGB)and aboveground net primary productivity(ANPP)sequences at three elevations using field-collected tree rings of Picea crassifolia in Qilian Mountains of Northwest *** results showed that(1)There were significant differences between AGB and ANPP at the three elevations,and the growth rate of AGB was the highest at the low elevation(55.99 t ha^(–1)10a^(–1)).(2)There are differences in the response relationship between the ANPP and climate factors at the three elevations,and drought stress is the main climate signal affecting the change of ANPP.(3)Under the future climate scenario,drought stress intensifies,and the predicted decline trend of ANPP at the three elevations from mid-century to the end of this century is–0.025 t ha^(–1)10a^(–1),respectively;–0.022 t ha^(–1)10a^(–1);At–0.246 t ha^(–1)10a^(–1),the level of forest productivity was significantly *** results reveal the elevation gradient differences in forest productivity levels and provide key information for studying the carbon sink potential of boreal forests.

关键词： global climate change tree ring aboveground net primary productivity aboveground biomass drought stress Qilian Mountains

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The Consistency of LSE Estimators in Partial Linear Regression Models under Mixing Random Errors

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1244-1272页

作者： Yun Bao YAO Yu Tan LÜ Chao LU wei WANG xue Jun WANG School of Mathematical Sciences Anhui UniversityHefei 230601P.R.China School of Big Data and Artificial Intelligence Chizhou UniversityChizhou 247000P.R.China School of Big Data and Statistics Anhui UniversityHefei 230601P.R.China

In this paper,we consider the partial linear regression model y_(i)=x_(i)β^(*)+g(ti)+ε_(i),i=1,2,...,n,where(x_(i),ti)are known fixed design points,g(·)is an unknown function,andβ^(*)is an unknown parameter to be estimated,random errorsε_(i)are(α,β)-mix_(i)ng random *** p-th(p>1)mean consistency,strong consistency and complete consistency for least squares estimators ofβ^(*)and g(·)are investigated under some mild *** addition,a numerical simulation is carried out to study the finite sample performance of the theoretical ***,a real data analysis is provided to further verify the effect of the model.

关键词： (α,β)-mixing random variables partial linear regression model least squares estimator consistency

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Vertebral Artery Stenting for Acute Multiple Cerebral Infarctions Caused by Vertebral Artery Dissection After Massage:A Case Report

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Chinese Medical Sciences Journal 2024年第2期39卷 149-154页

作者： ying-xue Cui Chuan-Jin Song xue-Si Hou Gui-Lin Liu Xu Ji Shao-Song Wang Department of Neurology Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing 100010China

Vertebral artery dissection is a rare pathology that can cause ischemic stroke in young *** massage,especially improper pulling manipulation,is a cause of vertebral artery *** present a case of 32-year old woman who developed acute multiple posterior circulation ischemic cerebral infarctions as a result of left vertebral artery V4 segment dissection after receiving neck *** underwent emergency vertebral artery stent implantation at the site of the *** were relieved the day after *** patient recovered without adverse complications or endovascular restenosis in the following year.

关键词： vertebral artery dissection acute ischemic stroke stent implantation endovascular therapy

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A survey of composite robot for aviation intelligent manufacturing application

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High Technology Letters 2024年第1期30卷 85-98页

作者：陶永 xue Jiao wei Hongxing LIU Haitao GAO He WANG Tianmiao School of Mechanical Engineering&Automation Beihang UniversityBeijing 100191P.R.China Research Institute of Aero Engine Beihang UniversityBeijing 100191P.R.China

With the rapid development of the aviation industry,the development of intelligent manufacturing equipment represented by composite robots has been paid close attention by the aviation *** on the analysis of the background and main structure function of composite robots,this paper focuses on the analysis of key technologies such as composite robot hardware design,visual sensing and planning system,integrated control of‘hands,feet,and eyes',multi-robot collaborative operation,and *** typical applications of composite robots in aviation intelligent manufacturing such as automatic drilling and connection of aircraft,aircraft surface spraying and finishing,parts handling,aircraft measurement,and inspection are *** development trends such as standardization of composite robots,integration of‘5G+cloud computing+AI',and fusion of intelligent sensors are proposed.

关键词： aviation manufacturing composite robot key technology development trend safety

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NQO1 Mediates Lenvatinib Resistance by Regulating ROS-induced Apoptosis in Hepatocellular Carcinoma

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Current Medical Science 2024年第1期44卷 168-179页

作者： wei xue Ting WANG Wen-jing TIAN Si-qi PANG Hua-feng ZHANG wei-dong JIA Department of General Surgery The First Affiliated Hospital of University of Science and Technology of ChinaDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230027China Institute of Health and Medicine Hefei Comprehensive National Science CenterHefei 230601China The Chinese Academy of Sciences Key Laboratory of Innate Immunity and Chronic Disease School of Basic Medical SciencesDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230027China

Objective Hepatocellular carcinoma(HCC)is the third leading cause of cancer-associated death *** a first-line drug for advanced HCC treatment,lenvatinib faces a significant hurdle due to the development of both intrinsic and acquired resistance among patients,and the underlying mechanism remains largely *** present study aims to identify the pivotal gene responsible for lenvatinib resistance in HCC,explore the potential molecular mechanism,and propose combinatorial therapeutic targets for HCC *** Cell viability and colony formation assays were conducted to evaluate the sensitivity of cells to lenvatinib and ***-Seq was used to determine the differences in transcriptome between parental cells and lenvatinib-resistant(LR)*** upregulated genes were analyzed by GO and KEGG ***,qPCR and Western blotting were employed to determine the relative gene expression ***,the intracellular reactive oxygen species(ROS)and apoptosis were detected by flow *** PLC-LR and Hep3B-LR were *** was a total of 116 significantly upregulated genes common to both LR cell *** GO and KEGG analyses indicated that these genes were involved in oxidoreductase and dehydrogenase activities,and reactive oxygen species ***,NAD(P)H:quinone oxidoreductase 1(NQO1)was highly expressed in LR cells,and was involved in the lenvatinib *** high expression of NQO1 decreased the production of ROS induced by lenvatinib,and subsequently suppressed the *** combination of lenvatinib and NQO1 inhibitor,dicoumarol,reversed the resistance of LR *** The high NQO1 expression in HCC cells impedes the lenvatinib-induced apoptosis by regulating the ROS levels,thereby promoting lenvatinib resistance in HCC cells.

关键词： hepatocellular carcinoma lenvatinib resistance NAD(P)H quinone oxidoreductase 1 reactive oxygen species apoptosis dicoumarol

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Ferroptosis:a critical mechanism of N^(6)-methyladenosine modification involved in carcinogenesis and tumor progression

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Science China(Life Sciences) 2024年第6期67卷 1119-1132页

作者： Qingqing wei Changning xue Mengna Li Jianxia wei Lemei Zheng Shipeng Chen Yumei Duan Hongyu Deng Faqing Tang wei Xiong Ming Zhou NHC Key Laboratory of Carcinogenesis Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangsha 410013China Cancer Research Institute and School of Basic Medical Sciences Central South UniversityChangsha 410078China The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education Central South UniversityChangsha 410078China Hunan Key Laboratory of Oncotarget Gene Hunan Key Laboratory of Cancer MetabolismHunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangsha 410013China

Ferroptosis is an iron-dependent regulatory cell necrosis induced by iron overload and lipid *** occurs when multiple redoxactive enzymes are ectopically expressed or show abnormal ***,the precise regulation of ferroptosis-related molecules is mediated across multiple levels,including transcriptional,posttranscriptional,translational,and epigenetic levels.N^(6)-methyladenosine(m^(6)A)is a highly evolutionarily conserved epigenetic modification in *** m^(6)A modification is commonly linked to tumor proliferation,progression,and therapy resistance because it is involved in RNA metabolic ***,accumulating evidence suggests that dysregulated ferroptosis caused by the m^(6)A modification drives tumor *** this review,we summarized the roles of m^(6)A regulators in ferroptosis-mediated malignant tumor progression and outlined the m^(6)A regulatory mechanism involved in ferroptosis *** also analyzed the potential value and application strategies of targeting m^(6)A/ferroptosis pathway in the clinical diagnosis and therapy of tumors.

关键词： ferroptosis m6A modification RNA methylation m^(6)A regulator tumor progression

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Enhancing reversible hydrogen storage performance of 2LiBH4–MgH2 via in-situ building heterogeneous nucleation sites

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Rare Metals 2024年第9期43卷 4367-4376页

作者： wei Chen Ya-Hui Sun Tian Xu xue-Bin Yu Guang-Lin Xia Department of Materials Science Fudan University

2LiBH4-MgH2composite is one of the most attractive reactive hydride composites with a theoretic hydrogen capacity of 10.8 wt%.However,the large nucleation restriction of MgB2during the second step of dehydrogenation results in sluggish hydrogen storage kinetics and high operating temperature,which hinders its practical application as on-board hydrogen storage ***,Al3Ti doped Al nanoparticles （AT NPs） are prepared by a facile chemical reduction reaction to improve the hydrogen storage performance of *** the initial H2desorption process,MgAlB4and TiB2that have identical crystal structure and low d-value mismatch with MgB2resulting from the reaction between AT NPs and 2LiBH4-MgH2composite serve as effective nucleation sites for the formation of *** a result,the apparent activation energy of the two-step H2desorption of AT NPs doped 2LiBH4-MgH2composite are notably decreased to （110.0±5.9） and（119.6±1.4） kJ·mol-1,which is 55.5 and 33.5 kJ·mol-1lower than that of the undoped *** importantly,a reversible hydrogen storage capacity of 9.2 wt%after 10cycles of H2desorption and adsorption could be achieved,corresponding to a capacity retention rate of 99%.The building of reactive bimetallic catalyst towards in situ formation of heterogeneous nucleation sites provides a new strategy for improving the hydrogen storage performance of reactive hydride composites.

关键词： Catalytic effects Heterogeneous nucleation Reactive hydride composites Reversible hydrogen storage

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Alleviative effects of Bacillus coagulans strains on irritable bowel syndrome-unraveling strain specificity through physiological and genomic analysis

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Food Science and Human Wellness 2024年第4期13卷 1845-1855页

作者： Jiang Cao Leilei Yu Jianxin Zhao Hao Zhang wei Chen Yuzheng xue Qixiao Zhai State Key Laboratory of Food Science and Technology Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China National Engineering Research Center for Functional Food Jiangnan UniversityWuxi 214122China Wuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch Wuxi 214122China Department of Gastroenterology Affiliated Hospital of Jiangnan UniversityWuxi 214122China

The high intraspecies heterogeneity of Baciillus coagulans leads to significant phenotypic differences among different ***,6 *** strains were tested in the present study using an irritable bowel syndrome(IBS)animal model to determine whether the IBS-alleviating effects of *** strains are *** results of this study showed that the ingestion of *** GBI-30,6086,and *** CCFM1041 significantly alleviated IBS symptoms in *** contrast,other *** strains showed no or limited alleviating effects on IBS *** to our experimental results,the two main common features of these strains were as follows:1)The resistance of vegetative cells to bile salts,and 2)ability to synthesize specific lipids and secondary *** strains based on these two indicators may greatly reduce costs and provide a basis for mining new functional *** *** results also suggest that administration of *** could significantly regulate microbiota dysbiosis in animal ***,the close relationships between the gut microbiota,gut microbiota metabolites,and IBS were further confirmed in this study.

关键词： Baciillus coagulans Irritable bowel syndrome Resistance to bile salts Comparative genomic analysis Gut microbiota

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Arbuscular mycorrhizal fungi inoculation and exogenous indole-3-acetic acid application induce antioxidant defense response to alleviate cadmium toxicity in Broussonetia papyrifera

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Pedosphere 2024年第2期34卷 447-459页

作者： xue LI Jingwei LIANG Hongjian wei Yuxuan KUANG Hui CHEN Ming TANG Wentao HU State Key Laboratory of Conservation and Utilization of Subtropical Agro-Bioresources Guangdong Laboratory for Lingnan Modern AgricultureGuangdong Key Laboratory for Innovative Development and Utilization of Forest Plant GermplasmCollege of Forestry and Landscape ArchitectureSouth China Agricultural UniversityGuangzhou 510642China

Cadmium(Cd)contamination in soil poses a huge threat to plants even at low concentrations;Broussonetia papyrifera has great potential in remediation of soil heavy metal ***,whether exogenous indole-3-acetic acid(IAA)application and arbuscular mycorrhizal fungi(AMF)have synergistic effects on Cd tolerance of *** remains *** investigate the effects of AMF inoculation and IAA application on the tolerance of *** to Cd stress,two experiments were conducted:the first to investigate the effect of AMF(Rhizophagus irregularis)inoculation on the tolerance of *** to Cd stress and the second to investigate the combined effects of AMF inoculation and IAA application on the tolerance of *** to Cd *** including endogenous hormone concentration,antioxidant defense response,malondialdehyde(MDA)content,and gene expression related to antioxidant enzyme system and hormone were *** results indicated that AMF alleviated Cd toxicity of *** by reducing MDA content and improving antioxidant enzyme activities and Cd absorption ***,the combination of AMF inoculation and IAA application had a synergetic effect on the tolerance of *** to Cd stress through upregulating BpAUX1 and BpAUX2,which might contribute to root growth and root xylem synthesis,and by upregulating BpSOD2 and BpPOD34 to enhance the antioxidant enzyme *** work provides a new insight into the application of IAA in the remediation of soil Cd pollution by mycorrhizal plants.

关键词： enzyme activity geneexpression heavy metal phytoremediation remediation Rhizophagus irregularis soil cadmium pollution stress tolerance

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