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Primary hepatic neuroendocrine tumor with multiple liver metastases:A case report with review of the literature

World Journal of Gastroenterology 2015年第10期21卷 3132-3138页

作者： Kai Yang ying-sheng cheng Ji-Jin Yang Xu Jiang Ji-Xiang Guo Department of Radiology and Medical Imaging Shanghai Sixth People’s Hospital Shanghai Jiaotong University Department of Interventional Radiology Affiliated Chang Hai Hospital of Second Military Medical University

We herein present a case involving a 41-year-old woman in whom ultrasound examination revealed multiple liver hemangiomas more than 3 years ***-up ultrasound examination revealed that the masses had significantly increased;the largest was located in the right lobe(about 8.2 cm×7.4 cm×6.0cm).Abdominal multidetector computed tomographyrevealed multiple well-circumscribed,heterogeneous,hypodense masses(largest,6.4 cm×6.3 cm×5.0cm)with significant contrast enhancement during the arterial and portal phases and with contrast washout and peripheral enhancement during the delayed *** resonance images demonstrated multiple well-circumscribed,heterogeneous,hypointense hepatic masses with significant contrast enhancement(largest,6.4 cm×6.5 cm×5.1 cm);multiple enlarged porta lymph nodes;and multiple s l i g h t l y e n l a rg e d re t ro p e r i t o n e a l l y m p h n o d e *** and immunohistochemical examination of the right mass biopsy specimen suggested a malignant neoplasm that had originated from a neuroendocrine cell type(grade 2 well-differentiated neuroendocrine carcinoma).After performing a systemic examination to exclude metastasis from an extrahepatic primary site,we considered that the masses had arisen from a primary hepatic neuroendocrine tumor with multiple liver *** patient underwent transcatheter arterial chemoembolization using a combination of oxaliplatin(150 mg)mixed with one bottle of gelatin sponge particles(560-710μm)and lipiodol(6 m L).Primary neuroendocrine tumors of the liver are extremely *** case is interesting because of the rarity of this neoplasm and previous misdiagnosis as multiple liver *** reported cases in the literature are also reviewed.

关键词： Liver Neoplasms-primary Neuroendocrine tumor Metas

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Silicone-covered biodegradable magnesium stent for treating benign esophageal stricture in a rabbit model

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World Journal of Gastroenterology 2019年第25期25卷 3207-3217页

作者： Kai Yang Jun Cao Tian-Wen Yuan Yue-Qi Zhu Bi Zhou ying-sheng cheng Department of Radiological Intervention Shanghai Sixth People's Hospital East Campus Affiliated to Shanghai University of Medicine&Health SciencesShanghai 201306China Department of Radiological Intervention Shanghai Sixth People's Hospital East Campus Affiliated to Shanghai Jiao Tong UniversityShanghai 201306China Department of Tumor Intervention Dahua HospitalShanghai 200237China Department of Radiological Intervention Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong UniversityShanghai 200233China

BACKGROUND Stent insertion can effective alleviate the symptoms of benign esophageal strictures(BES).Magnesium alloy stents are a good candidate because of biological safety,but show a poor corrosion resistance and a quick loss of mechanical support in *** To test the therapeutic and adverse effects of a silicone-covered magnesium alloy biodegradable esophageal *** Fifteen rabbits underwent silicone-covered biodegradable magnesium stent insertion into the benign esophageal stricture under fluoroscopic guidance(stent group).The wall reconstruction and tissue reaction of stenotic esophagus in the stent group were compared with those of six esophageal stricture models(control group).Esophagography was performed at 1,2,and 3 ***,six,and five rabbits in the stent group and two rabbits in the control groups were euthanized,respectively,at each time point for histological *** All stent insertions were well *** esophageal diameters at immediately,1,2 and 3 wk were 9.8±0.3 mm,9.7±0.7 mm,9.4±0.8 mm,and 9.2±0.5 mm,respectively(vs 4.9±0.3 mm before stent insertion;P0.05).CONCLUSION Esophageal silicone-covered biodegradable magnesium stent insertion is feasible for BES without causing severe injury or tissue *** study suggests that insertion of silicone-covered magnesium esophageal stent is a promising approach for treating BES.

关键词： Benign esophageal stricture Biodegradable stent Magnesium Silicone membrane

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Temporary self-expanding metallic stents for achalasia: A prospective study with a long-term follow-up

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World Journal of Gastroenterology 2010年第40期16卷 5111-5117页

作者： ying-sheng cheng Fang Ma ying-sheng cheng Yong-Dong Li Jun-Gong Zhao Chun-Gen Wu Ni-Wei Chen Wei-Xiong Chen Department of Clinical Center of Imaging Medicine The Tenth Affiliated People’s Hospital Tongji University Shanghai 200072 China Department of Diagnostic and Interventional Radiology The Sixth Affiliated People’s Hospital Shanghai Jiao Tong University Shanghai 200233 China Department of Gastroenterology The Sixth Af��liated People’s HospitalShanghai Jiao Tong UniversityShanghai 200233China

AIM: To compare the efficacy of self-expanding metallic stents (SEMSs) for the long-term clinical treatment of achalasia. METHODS: Ninety achalasic patients were treated with a temporary SEMS with a diameter of 20 mm (n = 30, group A), 25 mm (n = 30, group B) or 30 mm (n = 30, group C). Data on clinical symptoms, complications and treatment outcomes were collected, and follow-up was made at 6 mo and at 1, 3-5, 5-8, 8-10 and > 10 years, ***: Stent placement was successful in all patients. Although chest pain occurrence was high, stent migration was less in group C than in groups A and B. The clinical remission rate at 5-8, 8-10 and > 10 years in group C was higher than that in the other two groups. The treatment failure rate was lower in group C (13%) than in groups A (53%) and B (27%). SEMSs in group C resulted in reduced dysphagia scores and lowered esophageal sphincter pressures, as well as normal levels of barium height and width during all the follow-up time periods. Conversely, these parameters increased over time in groups A and B. The primary patency in group C was longer than in groups A and B. CONCLUSION: A temporary SEMS with a diameter of 30 mm is associated with a superior long-term clinical efficacy in the treatment of achalasia compared with a SEMS with a diameter of 20 mm or 25 mm.

关键词： Achalasia Dysphagia Self-expanding metallic stents Comparison

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Evaluation of a rabbit rectal VX2 carcinoma model using computed tomography and magnetic resonance imaging

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World Journal of Gastroenterology 2009年第17期15卷 2139-2144页

作者： Xin-Mei Liang Guang-Yu Tang ying-sheng cheng Bi Zhou Department of Radiology the Sixth People's Hospital of Shanghai Jiaotong University Institute of Medical Imaging of Shanghai Jiaotong University No. 600 Yishan Road Shanghai 200233 China Department of Radiology the Tenth People's Hospital of Shanghai Tongji University No. 301 Yanchang Middle Road Shanghai 200072 China

AIM： To establish a rabbit rectal VX2 carcinoma model for the study of rectal ***： A suspension of VX2 cells was injected into the rectum wall under the guidance of X-ray fluoroscopy. Computed tomography （CT） and magnetic resonance imaging （MRI） were used to observe tumorgrowth and metastasis at different phases. Pathological changes and spontaneous survival time of the rabbits were ***： Two weeks after VX2 cell implantation, the tumor diameter ranged 4.1-5.8 mm and the success implantation rate was 81.8%. CT scanning showed low-density loci of the tumor in the rectum wail, while enhanced CT scanning demonstrated a symmetrical intensification in tumor loci. MRI scanning showed alow signal of the tumor on T1-weighted imaging anda high signal of the tumor on T2-weighted *** types of signals were intensified with enhanced MRI. Metastases to the liver and lung could beobserved 6 wk after VX2 cell implantation, and a largearea of necrosis appeared in the primary tumor. The spontaneous survival time of rabbits with cachexia and multiple organ failure was about 7 wk after VX2 cell ***： The rabbit rectal VX2 carcinoma model we established has a high stability, and can be used in the study of rectal carcinoma.

关键词： Rectal carcinoma, Animal model Rabbit, VX2 Computed tomography Magnetic resonance imaging

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Emergency transcatheter arterial embolization for patients with acute massive duodenal ulcer hemorrhage

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World Journal of Gastroenterology 2012年第34期18卷 4765-4770页

作者： Yong-Li Wang ying-sheng cheng Li-Zhen Liu Zhong-Hui He Kun-Hong Ding Department of lnterventional Radiology Fengxian Branch Hospital of Affiliated 6th People's Hospital of Shanghai Jiaotong University Shanghai 201400 China Department of Diagnostic and Interven- tional Radiology Shanghai Jiaotong University Affiliated 6th People's Hospital Shanghai 200233 China

AIM：To evaluate the efficacy and safety of emergency transcatheter arterial embolization （ETAE） for patients with acute massive duodenal ulcer hemorrhage. METHODS：Twenty-nine consecutive patients with acute massive bleeding of duodenal ulcer were admitted to our hospital from 2006 to 2011. Superselective angiography of the celiac and gastroduodenal arteries was performed to find out the bleeding sites before ETAE, then, embolotherapy was done with gelatin sponge particles or microstrips via a 5 French angio-graphic catheter or 3 French microcatheter. After ETAE, further superior mesenteric arteriography was under-taken in case collateral circulation supplied areas of the duodenal ulcer. Technical and clinical success rates were analyzed. Changes in the mucous membrane were observed using endoscopy following ETAE. RESULTS：Angiography showed active bleeding with extravasation of contrast medium in seven cases with a 24% positive rate of celiac artery bleeding, and in 19 cases with a 65.5% rate of gastroduodenal artery bleeding. There were no angiographic signs of bleeding in three patients who underwent endoscopy prior to ETAE. Twenty-six patients achieved immediate hemostasis and technical success rate reached 90%. No hemostasis was observed in 27 patients within 30 d after ETAE and clinical success rate was 93%. Recurrent hemorrhage occurred in two patients who drank a lot of wine who were treated by a second embolotherapy in the same way. Five patients underwent transient ischem with light abdominal pain under xiphoid, spontaneous restoration without special treatment. No mucous necrosis happened to 29 cases for ischem of gastroduodenal arteries embolized. CONCLUSION：ETAE is an effective and safe measure to control acute massive bleeding of duodenal ulcer.

关键词： Transcatheter embolization Massive bleed-ing Duodenal ulcer Angiography

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Super-Flexible Through-the-Scope Self-Expandable Metallic Stent Insertion for the Management of Malignant Tortuous Hepatic or Splenic Flexure Colonic Obstruction

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Chinese Medical Journal 2018年第11期131卷 1381-1384页

作者： Kai Yang Yue-Qi Zhu Ni-Wei Chen Zhi-Gang Wang ying-sheng cheng Department of Radiology and Medical Imaging Shanghai Jiao Tong University Affiliated Shanghai Sixth People's Hospital Shanghai 200233 China Department of Gastroenterology Shanghai Jiao Tong University Affiliated Shanghai Sixth People's Hospital Shanghai 200233 China Department of Surgery Shanghai Jiao Tong University Affiliated Shanghai Sixth People's Hospital Shanghai 200233 China

To the Editor： The methods for obstruction of colon cancer include emergency surgery or self-expanding metallic stents （SEMSs）. SEMS insertion was shown to be a safe, easy, and effective treatment for left-sided malignant colon obstruction, for palliative treatment or as bridge to resection. The cases reported of SEMS insertion in the colon proximal to the splenic flexure were 〈5% of all studies. The long distances and the tortuosity of the distal bowel make it difficult to advance and position the stent in the target proximal colon, and obstruction of right colon has traditionally been managed by acute operation.

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支架成形术在食管良恶性狭窄中的应用进展

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世界华人消化杂志 2008年第25期16卷 2841-2847页

作者：李烽程英升上海交通大学附属第六人民医院放射科上海交通大学影像医学研究所上海市200233

支架成形术目前已广泛用于改善晚期食管癌所致的吞咽困难.随着食管支架的不断改进,现在有许多新的支架用于临床治疗.这些支架在原来的基础上增加抗反流瓣膜、装有可回收装置或载有125I颗粒等以及出现生物可降解支架.支架的改进能减少并... 详细信息

支架成形术目前已广泛用于改善晚期食管癌所致的吞咽困难.随着食管支架的不断改进,现在有许多新的支架用于临床治疗.这些支架在原来的基础上增加抗反流瓣膜、装有可回收装置或载有125I颗粒等以及出现生物可降解支架.支架的改进能减少并发症并提高生存率.许多非手术性姑息方法如腔内激光治疗、光动力疗法、电凝及腔内近距离放射治疗都用来治疗食管狭窄,但最迅速缓解症状的方法就是食管支架成形术.支架治疗良性食管狭窄的报道也不断增多,应用暂时性支架及生物可降解支架可以很好地改善效果.

关键词：食管狭窄支架生物可降解支架

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Clinical application of self-expanding metallic stent in the management of acute left-sided colorectal malignant obstruction

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World Journal of Gastroenterology 2006年第5期12卷 755-759页

作者： You-Ben Fan ying-sheng cheng Ni-Wei Chen Hui-Min Xu Zhe Yang Yue Wang Yao Huang Qi Zheng Department of Surgery Sixth People's Hospital Shanghai Jiaotong University Shanghai 200233 China Department of Radiology Sixth People's Hospital Shanghai Jiaotong University Shanghai 200233 China

AIM： To summarize our experience with the application of self-expanding metallic stent （SEMS） in the management of acute left-sided colorectal malignant obstruction. METHODS： A retrospective chart review of all patients undergoing placement of SENS between April 2000 and January 2004 was performed. RESULTS： Insertion of SENS was attempted in 26 patients under fluoroscopic guidance with occasional endoscopic assistance. The sites of lesions were located in splenic flexure of two patients, left colon of seven patients, sigmoid colon of eight patients and rectum of nine patients. The intended uses of SENS were for palliation in 7 patients and as a bridge to elective surgery in 19 patients. In the latter group, placement of SENS allowed for preoperative systemic and bowel preparation and the following one-stage anastomosis. Successful stent placement was achieved in 22 （85%） of the 26 patients. The clinical bowel obstruction resolved 24 hours after successful stent placement in 21 （95%） patients. Three SENS-related minor complications occurred, two stents migrated and one caused anal pain. CONCLUSION： SEMS represents an effective and safe tool in the management of acute malignant colorectal obstruction. As a bridge to surgery, SEMS can provide time for systematic support and bowel preparation and obviate the need for fecal diversion or on-table lavage. As a palliative measure, SEMS can eliminate the need for emergent colostomy.

关键词： SEMS Acute left-sided colorectal malignant obstruction

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中国胃肠影象学发展的50年

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世界华人消化杂志 2000年第11期8卷 1225-1232页

作者：程英升尚克中上海市第六人民医院放射科上海市200233

目的回顾中国胃肠影象学50年发展的历史.方法 1949-10/1999-10,中国在胃肠影象设备和成象技术的发展概况、中华放射学杂志(《中放》)上发表胃肠影象学论著数量和分布年代情况、国内公开出版的胃肠影象学专著数量和种类、在胃肠影象学方... 详细信息

目的回顾中国胃肠影象学50年发展的历史.方法 1949-10/1999-10,中国在胃肠影象设备和成象技术的发展概况、中华放射学杂志(《中放》)上发表胃肠影象学论著数量和分布年代情况、国内公开出版的胃肠影象学专著数量和种类、在胃肠影象学方面获得的卫生部和国家科技进步奖等方面,进行回顾复习.结果在此50年中,胃肠影象设备从20世纪50年代的200mA的普通 X 线机发展到90年代计算机摄影(CR)或直接摄影(DR)X 线机.胃肠影象成象技术从20世纪50年代普通 X 线成象发展到90年代的数字成象、电子计算机体层摄影(CT)和磁共振(MR)仿真内镜成象技术.《中放》共发表胃肠影象学论著211篇,占《中放》全部论著的8.43%.50年代《中放》发表的论著,着重常见疾病平片诊断和胃肠单对比造影表现的描述;90年代《中放》发表的论著,着重胃肠成象新技术(CT,MR,CR 或 DR)的应用和综合应用和介入放射学的广泛应用.出版胃肠影象学专著12种,从50年代陈祯琳编写的《胃肠 X 线检查诊断图谱》到90年代榭敬霞主编《消化道疾病的影象诊断图谱》.与胃肠影象学内容有关的卫生部和国家科技进步奖3项.70年代陈根芬等《"华山2000型"、"医工78型"-X 线双重造影硫酸钡剂研究》获得国家发明三等奖;到90年代尚克中等《胃肠道双对比造影(DC)的实验及应用系列研究》获得卫生部科技进步三等奖.结论中国胃肠影象学50年来在紧跟世界胃肠影象学发展的同时,开创了具有中国特色的胃肠影象学发展和研究道路.

关键词：中国胃肠影像学历史发展

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小肠疾病影像学诊断新进展

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世界华人消化杂志 2007年第7期15卷 669-676页

作者：程英升宋富珍上海交通大学附属第六人民医院放射科上海交通大学影像医学研究所上海市200233

小肠是胃肠道最长的器官,因其走行弯曲,肠管常互相重叠,传统的胃肠道和内镜检查单纯地观察消化道腔内结构,尚不能很好显示肠壁和腔外结构.多层螺旋CT(MSCT)和磁共振成像(MRI)具有快速扫描和三维后处理能力,能清晰反映肠壁和肠腔外的病变... 详细信息

小肠是胃肠道最长的器官,因其走行弯曲,肠管常互相重叠,传统的胃肠道和内镜检查单纯地观察消化道腔内结构,尚不能很好显示肠壁和腔外结构.多层螺旋CT(MSCT)和磁共振成像(MRI)具有快速扫描和三维后处理能力,能清晰反映肠壁和肠腔外的病变.新的影像技术CT小肠灌肠造影(CTE)、MR小肠灌肠造影(MRE)具有良好的软组织对比度及三维成像能力,不仅可以观察黏膜,同时能够分析肠管周围的改变,提高了人们对小肠疾病影像诊断的认识.本文就近年来小肠疾病影像学诊断的进展及今后努力的方向作一述评.

关键词：多层螺旋CT 磁共振成像小肠疾病诊断小肠造影

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