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Nonlinear Dynamical Behavior in Neuron Model Based on Small World Network with Attack and Repair Strategy

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Communications in Theoretical Physics 2008年第4期49卷 965-970页

作者： YANG qiu-ying ZHANG ying-Yue ZHANG Gui-Qing CHEN Tian-Lun Department of Physics Nankai University Tianjin 300071 China

In this paper, we investigate the effect due to the change of topology structure of network on the nonlinear dynamical behavior, by virtue of the OFC neuron evolution model with attack and repair strategy based on the small world. In particular, roles of various parameters relating to the dynamical behavior are carefully studied and analyzed. In addition, the avalanche and EEC-like wave activities with attack and repair strategy are also explored in detail in this work.

关键词： attack repair self-organized criticality small world network

Nonlinear Dynamical Behavior in BS Evolution Model Based on Small-World Network Added with Nonlinear Preference

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Communications in Theoretical Physics 2007年第7期48卷 137-142页

作者： ZHANG ying-Yue YANG qiu-ying CHEN Tian-Lun Department of Physics,Nankai University,Tianjin 300071,China Department of Physics Nankai University Tianjin 300071 China

We introduce a modified small-world network adding new links with nonlinearly preferential connectioninstead of adding randomly,then we apply Bak-Sneppen(BS)evolution model on this *** study severalimportant structural properties of our network such as the distribution of link-degree,the maximum link-degree,and thegth of the shortest *** further argue several dynamical characteristics of the model such as the important criticalvalue f_c,the f_0 avalanche,and the mutating condition,and find that those characteristics show panticular behaviors.

关键词： power-law behavior small-world network evolution model nonlinear preference

“国际商务合同”课程教学中案例教学法的应用

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黑龙江高教研究 2015年第2期33卷 163-165页

作者：裘莹莹淮阴工学院外国语学院江苏淮安223003

案例教学应用于"国际商务合同"教学是对传统教学方式的一次改革,是"国际商务合同"课程的自身特征及其教学目标所决定的。从教学实践对案例教学法在"国际商务合同"教学中的应用进行探讨,从教师和学生两个角度分别阐述案例教学的组织实施... 详细信息

案例教学应用于"国际商务合同"教学是对传统教学方式的一次改革,是"国际商务合同"课程的自身特征及其教学目标所决定的。从教学实践对案例教学法在"国际商务合同"教学中的应用进行探讨,从教师和学生两个角度分别阐述案例教学的组织实施步骤,分析应用过程中存在的难点,提出相应的对策,以期为"国际商务合同"教学提供一些新的思路。

关键词：案例教学法国际商务合同教学

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复杂层次状态机的一种解决方案

煤炭技术 2013年第3期32卷 195-197页

作者：丘映莹广西经贸职业技术学院南宁530021

分析了有限状态机的软件实现方法,为有效解决复杂多层次状态机的设计与实现问题创造性地引入了树型逻辑的思想,并给出了普适的实现方法和步骤,结合具体案例进行应用现实的分析。

关键词：遍历层次状态机状态转移矩阵

从1例肾功能损害患者病例报告看个体化药学监护方法

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中国新药杂志 2008年第14期17卷 1268-1271页

作者：应颖秋翟所迪北京大学第三医院药剂科北京100083

目的:探讨肾功能损害患者个体化药学监护方法的可行性。方法:对1例肾功能损害患者进行药学监护,重点基于肾功能进行剂量调整,监测相关指标并评价治疗效果。结果:药师按照该方法对肾功能损害患者进行药学监护,针对性更强。结论:肾功能损... 详细信息

目的:探讨肾功能损害患者个体化药学监护方法的可行性。方法:对1例肾功能损害患者进行药学监护,重点基于肾功能进行剂量调整,监测相关指标并评价治疗效果。结果:药师按照该方法对肾功能损害患者进行药学监护,针对性更强。结论:肾功能损害患者个体化药学监护方法是肾专科药师有效的工作方法。

关键词：肾功能损害个体化药学监护

Ceftriaxone-induced immune hemolytic anemia in a case with large vestibular aqueduct syndrome after cochlear implant

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Chinese Medical Journal 2019年第1期132卷 100-102页

作者： Yu Wang Tao Pan Fu-Rong Ma Ji-Jun Wang Ke Zhang Wei-Wei Pan Jing-Hui Zhang Zhan-Miao Yi ying-qiu ying Department of Otolaryngology Peking University Third HospitalBeijing 100191China Department of Hematology Peking University Third HospitalBeijing 100191China Department of Pediatrics Peking University Third HospitalBeijing 100191China Department of Pharmacy Peking University Third HospitalBeijing 100191China

To the Editor:Drug-induced immune hemolytic anemia (DIIHA)is a rare but severe ***,a third-generation cephalosporin with a wide antibacterial spectrum and effective antibacterial action,is one of the most common drugs causing DIIHA.^[1]Ceftriaxoneinduced immune hemolytic anemia (CIIHA)is a potentially fatal complication.^[2]Most of the patients were *** reported fatality rate of CIIHA was as high as 40%.

关键词： Ceftriaxone-induced immune hemolytic anemia large vestibular aqueduct syndrome cochlear implant

Spinal cord injury and cholelithiasis

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Hepatobiliary & Pancreatic Diseases International 2004年第4期3卷 595-598页

作者： Chang-Suo Xia, ying-qiu Han, Xuan-ying Yang and Guang-Xiang Hong Qingdao, China Department of Orthopaedics, Affiliated Hospital of Medical College , Qingdao University, Qingdao 266003 , China and Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 , China Department of Orthopaedics Affiliated Hospital of Medical College Qingdao University Qingdao 266003 China. xcs_009@***

BACKGROUND: Spinal cord injury (SCI) is found to be related to increased prevalence of gallstones and acute acal- culous cholecystitis. In this study we assessed the prevalence of cholelithiasis in male patients with SCI and the correla- tion of cholelithiasis with age and weight of patients, level of injury, as well as severity and duration of SCI. METHODS: One hundred male SCI patients (58 patients rated ASIA A or B and 42 rated ASIA C or D) aged more than 20 years (average 46.5 years) suffered from a spinal cord injury for more than one year. One hundred male vo- lunteers served as controls without SCI and biliary diseases (age range 20-68 years; average 42.6 years). The two groups were subjected to ultrasonography of the gallbladder and biliary tract. RESULTS: The prevalence of cholelithiasis in the group of SCI patients and the control group was 26% and 10% re- spectively. Significant differences in the prevalence of cho- lelithiasis were found between the normal controls and SCI patients and between high- and low-level injury (P 0.05). CONCLUSIONS: SCI represents a major risk factor for the development of cholelithiasis, especially in patients with high-level injury. Cholelithiasis in SCI patients is not relat- ed to their age and weight, the severity of spinal lesion, and the duration of spinal cord injury.

关键词： spinal cord injury cholelithiasis gallstones risk factors

碳青霉烯类抗菌药物延长或持续输注治疗严重感染的疗效及安全性的系统评价

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中国医院药学杂志 2017年第16期37卷 1622-1628,1634页

作者：陈灿应颖秋闫盈盈翟所迪北京大学第三医院药剂科北京100191 北京大学药学院药事管理与临床药学系北京100191

目的:系统评价碳青霉烯类抗菌药物延长或持续输注方式(2~4 h输注或持续24 h输注)对比传统间断输注方式(0.5~1 h输注)治疗严重感染的疗效和安全性,以期为临床治疗提供循证参考。方法:计算机检索Cochrane图书馆、EMBase、PubMed、维普中... 详细信息

目的:系统评价碳青霉烯类抗菌药物延长或持续输注方式(2~4 h输注或持续24 h输注)对比传统间断输注方式(0.5~1 h输注)治疗严重感染的疗效和安全性,以期为临床治疗提供循证参考。方法:计算机检索Cochrane图书馆、EMBase、PubMed、维普中文科技期刊数据库、中国期刊全文数据库、万方数据库,检索碳青霉烯类抗菌药物延长或持续输注方式(观察组)对比间断输注方式(对照组)治疗严重感染的随机对照研究(RCTs),由2位研究者独立筛选文献、提取资料,并评价纳入研究的偏倚风险后,采用RevMan 5.3软件进行Meta分析。结果:共纳入20个RCTs,合计1 695例患者。Meta分析结果显示:(1)观察组患者临床有效率[RR=1.27,95%CI(1.18,1.36),P<0.000 01]和细菌清除率[RR=1.28,95%CI(1.18,1.39),P<0.000 01]显著高于对照组,且持续输注的细菌清除效果优于延长输注;(2)观察组的耐药菌产生率显著降低[RR=0.30,95%CI(0.14,0.65),P=0.002];(3)亚组分析显示持续输注组[MD=-6.08,95%CI(-6.68,-5.48),P<0.000 01]和延长输注组[MD=-3.06,95%CI(-3.56,-2.56),P<0.000 01]均能使ICU住院时间显著缩短;(4)观察组碳青霉烯类抗菌药物用药疗程也显著缩短[MD=-0.76,95%CI(-1.29,-0.22),P=0.005];(5)观察组不良反应发生率[RR=0.98,95%CI(0.70,1.36),P=0.89]与对照组比较,差异无统计学意义;(6)对于呼吸系统感染,与对照组相比,观察组具有较好的临床疗效,且不良反应发生率未增加。结论:与间断输注方式相比,延长或持续输注碳青霉烯类抗菌药物可提高治疗严重感染的疗效,两者安全性相当。上述结论尚需开展更多高质量研究予以验证。

关键词：碳青霉烯类抗菌药物延长输注持续输注严重感染 Meta分析

持续静脉血液滤过联合体外膜肺氧合治疗1例急性重症胰腺炎的万古霉素个体化治疗方案报道

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北京大学学报（医学版） 2018年第5期50卷 915-920页

作者：何娜闫盈盈应颖秋伊敏么改琦葛庆岗翟所迪北京大学第三医院药剂科北京100191 北京大学药学院药事管理与临床药学系北京100191 北京大学第三医院重症医学科北京100191

万古霉素是临床常用的糖肽类抗菌药物,用于革兰阳性球菌感染,特别是耐甲氧西林金黄色葡萄球菌（methicillin-resistant Staphylococcus aureus,MRSA）感染的一线治疗,具有治疗窗窄、肾毒性的特点。2016年《中国万古霉素治疗药物监测指... 详细信息

万古霉素是临床常用的糖肽类抗菌药物,用于革兰阳性球菌感染,特别是耐甲氧西林金黄色葡萄球菌（methicillin-resistant Staphylococcus aureus,MRSA）感染的一线治疗,具有治疗窗窄、肾毒性的特点。2016年《中国万古霉素治疗药物监测指南》推荐对重症患者进行万古霉素治疗药物监测,对于重症成人患者推荐10～20 mg/L为目标谷浓度,并基于药代动力学原理和方法进行个体化给药。

关键词：万古霉素体外膜肺氧合持续血液滤过药物监测