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Dopamine D2 receptors in the dorsomedial prefrontal cortex modulate social hierarchy in male mice

Current Zoology 2023年第6期69卷 682-693页

作者： Lai-Fu Li Zi-Lin Li Bai-Lin Song Yi Jiang Yan Wang Hua-Wei Zou Lun-Guang Yao ying-juan liu Henan Key Laboratory of Insect Biology in Funiu Mountain Henan International Joint Laboratory of Insect BiologyCollege of Life Science and Agricultural EngineeringNanyang Normal UniversityNanyang 473061HenanChina Research Center of Henan Provincial Agricultural Biomass Resource Engineering and Technology College of Life Science and AgricultureNanyang Normal UniversityNanyang 473061HenanChina

Social hierarchy greatly influences behavior and *** human and animal studies have signaled the medial prefrontal cortex(mPFC)as specifically related to social *** D1 receptors(D1Rs)and D2 receptors(D2Rs)are abundantly expressed in the mPFC,modulat-ing its ***,it is unclear how DR-expressing neurons in the mPFC regulate social ***,using a confrontation tube test,we found that most adult C57BL/6J male mice could establish a linear social rank after 1 week of *** rank individuals showed social anxiety together with decreased serum testosterone levels.D2R expression was significantly downregulated in the dorsal part of mPFC(dmPFC)in lower rank individuals,whereas D1R expression showed no significant difference among the rank groups in the whole *** knockdown of D2Rs in the dmPFC led to mice being particularly prone to lose the contests in the confrontation tube ***,simultaneous D2R activation in the subordinates and D2R inhibition in the dominants in a pair switched their dominant-subordinate *** above results indicate that D2Rs in the dmPFC play an important role in social *** findings provide novel insights into the divergent func-tions of prefrontal D1Rs and D2Rs in social dominance,which may contribute to ameliorating social dysfunctions along with abnormal social hierarchy.

关键词： dopamine receptors medial prefrontal cortex social dominance social hierarchy tube test

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Clinical utilization of microembolus detection by transcranial Doppler sonography in intracranial stenosis-occlusive disease

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Chinese Medical Journal 2013年第7期126卷 1355-1359页

作者： WU Xiu-juan XING ying-qi WANG juan liu Kang-ding Department of Neurology First Bethune Hospital of Jilin University Changchun Jilin 130021 China

Objective To discuss the clinical ultiliazation and significance of microembolus detection by transcranial Doppler （TCD） sonography in intracranial stenosis-occlusive disease. Data sources All related articles in this review were mainly searched from PubMed published in English from 1996 to 2012 using the terms of microembolic signal, transcranial Doppler, intracranial stenosis, stroke. Study selection Original articles and reviews were selected if they were related to the clinical utilization of microembolus detection in intracranial stenosis-occlusive disease. Results Intracranial stenosis is a significant cause of cerebral emboli, and microembolus detection by TCD sonography were widely used in exploring the mechanisms of ischemic stroke with intracranial stenosis （including the middle cerebral artery stenosis and the vertebral-basilar stenosis）, evaluating the prognosis of acute stroke, evaluating the therapeutic effects, and predicting the recurrent events of stroke. Conclusion Microembolus detection by TCD sonography plays an important role in the cerebral ischemic stroke patients with intracranial stenosis.

关键词： microembolic signal transcranial Doppler intracranial stenosis stroke

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Flank gland-secreted putative chemosignals pertaining to photoperiod,endocrine states,and sociosexual behavior in golden hamsters

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Current Zoology 2010年第6期56卷 800-812页

作者： ying-juan liu Da-Wei WANG Lixing SUN Jin-Hua ZHANG Jian-Xu ZHANG State Key Laboratory of Integrated Management of Pest Insects and Rodents in Agriculture Institute of Zoology Chinese Academy of Sciences Beichenxi Rdl-5 Beijing 100101 China School of Life Science Beijing Normal University Beijing 100875 China School of Biological Sciences Beijing Forestry University Beijing 100083 China Department of Biological Sciences Central Washington University Ellensburg WA 98926-7537 USA

Behavioral studies have shown that flank glands are involved in chemical communication in golden hamsters Mesocricetus auratus but little chemical analysis has been conducted on volatiles arising from these glands. Using gas chromatography-mass spectrometry, we detected compounds from the flank glands of males, only eight of which were also produced in females. Based on these chemical data we performed a number of further experiments. By manipulating light we found that males exposed to short-photoperiods developed smaller flank glands than those exposed to long-photoperiods. Six flank gland volatiles reduced in relative abundance, which possibly coded for reproductive status of males of this seasonally breeding hamster species. Through dyadic encounters, we were able to induce the formation of dominant-subordinate relationships and show that two glandular compounds became high in relative abundance and may function as dominance pheromones. Castration eliminated all male-specific compounds resulting from flank glands, but bilateral ovariectomies only affected one compound in females. Once these ovariectomized females were treated with testosterone, their glandular compounds resembled those of males, suggesting these compounds are under the main control of androgen. Two female putative pheromones, tetradeeanoic acid and hexadecanoic acid, were used in binary choice tests and were both found to attract males over females. Applying a solution of these pheromone compounds to adult males also suppressed their agonistic behavior [Current Zoology 56 （6）： 800-812, 2010].

关键词： Dominance Flank gland Gonadectomy Photoperiod Putative pheromone Testosterone

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Flexible molecules dedicate to release strain of inverted inorganic perovskite solar cell

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Journal of Energy Chemistry 2025年第1期100卷 87-93页

作者： Hongrui Sun Sanlong Wang Pengyang Wang Yali liu Shanshan Qi Biao Shi ying Zhao Xiaodan Zhang Institute of Photoelectronic Thin Film Devices and Technology Renewable Energy Conversion and Storage Center State Key Laboratory of Photovoltaic Materials and CellsNankai University Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Haihe Laboratory of Sustainable Chemical Transformations Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

The tensile strain in inorganic perovskite films induced by thermal annealing is one of the primary factors contributing to the inefficiency and instability of inorganic perovskite solar cells （IPSCs）,which reduces the defect formation ***,a flexible molecule 5-maleimidovaleric acid （5-MVA） was introduced as a strain buffer to release the residual strain of *** anhydride and carboxyl groups in 5-MVA interact strongly with the uncoordinated Pb2+through Lewis acid-base reaction,thus tightly“pull”the perovskite *** in-between soft carbon chain increased the structural flexibility of CsPbI2.85Br0.15perovskite materials,which effectively relieved the intrinsic internal strain of CsPbI2.85Br0.15,resisted the corrosion of external strain,and also reduced the formation of defects such as VIand *** addition,the introduction of 5-MVA improved crystal quality,passivated residual defects,and narrowed energy level ***,power conversion efficiency （PCE） of NiOxbased inverted IPSCs increased from 19.25% to 20.82% with the open-circuit voltage enhanced from 1.164 V to 1.230 *** release of strain also improved the stability of CsPbI2.85Br0.15perovskite films and devices.

关键词： Inverted inorganic perovskite solar cells Flexible molecules Strain release Crystallization Energy barrier High PCE

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Observation of topological charge transformations in acoustic vortex using passive periodic systems

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 140-147页

作者： Di-Chao Chen Xie liu Changqing Xu Da-Jian Wu ying Cheng Xiao-Jun liu School of Physics and Technology Nanjing Normal University Key Laboratory of Modern Acoustics School of Physics Nanjing University

Vortex transmutation utilizes a periodic system, which not only enables the alteration of the topological charge(TC) of unstable input vortices but also facilitates their transformation into stable structures. This approach is crucial for investigating the characteristics of vortices in various wave systems. Here, we achieve acoustic vortex TC transmutation by employing a welldesigned dual-structured plate external system(DPES). The interactions between the acoustic vortex and the finite-order discrete rotational symmetry lead to the transformation of its topological charge when complete rotational symmetry is broken to Nthorder discrete symmetry. Our results experimentally demonstrate the acoustic vortex TC transmutation based on passive artificial structures, enabling numerous applications in particle manipulation and information multiplexing as well as advancing our understanding and control over free-space acoustic vortices.

关键词： acoustic vortex topological charge transformation artificial structure

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NOX4 exacerbates Parkinson's disease pathology by promoting neuronal ferroptosis and neuroinflammation

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Neural Regeneration Research 2025年第7期20卷 2038-2052页

作者： Zhihao Lin Changzhou ying Xiaoli Si Naijia Xue Yi liu Ran Zheng ying Chen Jiali Pu Baorong Zhang Department of Neurology The Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina

Parkinson's disease is primarily caused by the loss of dopaminergic neurons in the substantia nigra ***,a novel form of regulated cell death characterized by iron accumulation and lipid peroxidation,plays a vital role in the death of dopaminergic ***,the molecular mechanisms underlying ferroptosis in dopaminergic neurons have not yet been completely *** oxidase 4 is related to oxidative stress,however,whether it regulates dopaminergic neuronal ferroptosis remains *** aim of this study was to determine whether NADPH oxidase 4 is involved in dopaminergic neuronal ferroptosis,and if so,by what *** found that the transcriptional regulator activating transcription factor 3 increased NADPH oxidase 4 expression in dopaminergic neurons and astrocytes in an 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced Parkinson's disease *** oxidase 4 inhibition improved the behavioral impairments observed in the Parkinson's disease model animals and reduced the death of dopaminergic ***,NADPH oxidase 4 inhibition reduced lipid peroxidation and iron accumulation in the substantia nigra of the Parkinson's disease model ***,we found that NADPH oxidase 4 interacted with activated protein kinase Cαto prevent ferroptosis of dopaminergic ***,by lowering the astrocytic lipocalin-2 expression,NADPH oxidase 4 inhibition reduced 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced *** findings demonstrate that NADPH oxidase 4 promotes ferroptosis of dopaminergic neurons and neuroinflammation,which contribute to dopaminergic neuron death,suggesting that NADPH oxidase 4 is a possible therapeutic target for Parkinson's disease.

关键词： dopaminergic neuron ferroptosis NADPH oxidase 4(NOX4) neuroinflammation Parkinson's disease

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Multi boron-doping effects in hard carbon toward enhanced sodium ion storage

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Journal of Energy Chemistry 2025年第1期100卷 730-738页

作者： Peng Zheng Wang Zhou ying Mo Biao Zheng Miaomiao Han Qin Zhong Wenwen Yang Peng Gao Lezhi Yang Jilei liu College of Materials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean Energy Hunan Province Key Laboratory for Advanced Carbon Materials and Applied Technology Hunan University Greater Bay Area Institute for Innovation Hunan University Changsha Research Institute of Mining & Metallurgy Co. LTD.

Hard carbon （HC） has been considered as promising anode material for sodium-ion batteries （SIBs）.The optimization of hard carbon’s microstructure and solid electrolyte interface （SEI） property are demonstrated effective in enhancing the Na+storage capability,however,a one-step regulation strategy to achieve simultaneous multi-scale structures optimization is highly ***,we have systematically investigated the effects of boron doping on hard carbon’s microstructure and interface chemistry.A variety of structure characterizations show that appropriate amount of boron doping can increase the size of closed pores via rearrangement of carbon layers with improved graphitization degree,which provides more Na+storage ***-situ Fourier transform infrared spectroscopy/electrochemical impedance spectroscopy （FTIR/EIS） and X-ray photoelectron spectroscopy （XPS） analysis demonstrate the presence of more BC3and less B–C–O structures that result in enhanced ion diffusion kinetics and the formation of inorganic rich and robust SEI,which leads to facilitated charge transfer and excellent rate *** a result,the hard carbon anode with optimized boron doping content exhibits enhanced rate and cycling *** general,this work unravels the critical role of boron doping in optimizing the pore structure,interface chemistry and diffusion kinetics of hard carbon,which enables rational design of sodium-ion battery anode with enhanced Na+storage performance.

关键词： X ray photoelectron spectroscopy

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Inactivation of the bed nucleus of the stria terminalis suppresses the innate fear responses of rats induced by the odor of cat urine

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畜牧与兽医 2012年第S1期44卷 376-376页

作者： Hai-Yang Xu ying-juan liu Ming-Yuan Xu Jin-Hua Zhang Jian-Xu Zhang Yi-Jun Wu Laboratory of Molecular Toxicology Institute of Zoology Chinese Academy of Sciences Group for Animal Behavior and Chemical Communication State Key Laboratory of Integrated Management of Pest Insects and RodentsInstitute of Zoology Chinese Academy of Sciences

In this study,we investigated whether two brain regions,the bed nucleus of the stria terminalis(BNST)and the basolateral amygdala(BLA),affected male rats(Rattus norvigicus)ability to innately discriminate between a predator odor(cat urine)and female rat ***,a GABAa receptor agonist,was bilaterally microinjected into either the BNST or BLA of rats through

关键词： stria nucleus urine innate discriminate predator implanted Rattus nuclei agonist

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Sora文生视频大模型对学术期刊出版的机遇、挑战及应对

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新疆师范大学学报（哲学社会科学版） 2025年第2期46卷 79-88页

作者：刘娟新疆师范大学期刊社新疆乌鲁木齐830017

随着Sora文生视频大模型的迅猛发展,学术期刊出版正在经历深刻的变革与重塑。Sora技术的多模态特征与智能化能力,一方面促进学术信息的动态整合与开放获取,推动传统出版模式向协同创新与知识共享的新范式转型;另一方面,赋予著作权归属... 详细信息

随着Sora文生视频大模型的迅猛发展,学术期刊出版正在经历深刻的变革与重塑。Sora技术的多模态特征与智能化能力,一方面促进学术信息的动态整合与开放获取,推动传统出版模式向协同创新与知识共享的新范式转型;另一方面,赋予著作权归属和著作权风险治理等新的价值意蕴。面对Sora文生视频大模型对学术期刊出版带来的机遇和挑战,学术期刊应构建跨学科协作网络、重塑基于价值的学术评价标准、创新人才培养机制,强化全球学术出版治理。文本通过系统分析大语言模型、文生视频大模型驱动下的新兴学术生态,旨在为学术界提供理论视角和实践样态,实现知识生产的原创性与伦理性,推动学术出版在新技术环境中的学术治理现代化及可持续高质量发展。

关键词： Sora 学术期刊出版技术伦理学术伦理学术生态系统

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恶性蝾螈瘤的CT及MRI表现(附3例报告及文献复习)

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实用放射学杂志 2008年第1期24卷 84-86页

作者：任静常英娟宦怡刘莹刘燕丽第四军医大学西京医院放射科第四军医大学西京医院放射科陕西西安710032

目的提高对恶性蝾螈瘤的影像学认识。方法报告3例经病理证实的恶性蝾螈瘤的CT和MRI表现,并作文献复习。结果本组3例罕见的恶性蝾螈瘤,1例原发于前列腺伴有肺转移和神经纤维瘤病Ⅰ型,1例发生于左侧臀部,1例发生于右侧上颌窦伴有窦壁骨质... 详细信息

目的提高对恶性蝾螈瘤的影像学认识。方法报告3例经病理证实的恶性蝾螈瘤的CT和MRI表现,并作文献复习。结果本组3例罕见的恶性蝾螈瘤,1例原发于前列腺伴有肺转移和神经纤维瘤病Ⅰ型,1例发生于左侧臀部,1例发生于右侧上颌窦伴有窦壁骨质破坏。CT和MRI表现为较大的软组织肿块影,强烈提示恶性肿瘤,T2WI均呈高信号,其内可见环形低信号分隔影。结论恶性蝾螈瘤尽管最终确诊需依赖病理组织学检查,CT和MRI在定位诊断及鉴别良恶性方面具有重要作用。

关键词：恶性蝾螈瘤磁共振成像体层摄影术,X线计算机

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