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The formation and evolution of massive galaxies

Research in Astronomy and Astrophysics 2021年第9期21卷 53-62页

作者： ying-jie jing Yu Rong jie Wang Qi Guo Liang Gao Key Laboratory for Computational Astrophysics National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China Instituto de Astrofísica Pontificia Universidad Católica de ChileAv.Vicuña Mackenna 4860MaculSantiagoChile Institute of Computational Cosmology Department of PhysicsUniversity of DurhamScience LaboratoriesSouth RoadDurham DH13LEUK FONDECYT

The discovery of massive galaxies at high redshifts,especially the passive ones,poses a big challenge for the current standard galaxy formation *** we use the semi-analytic galaxy formation model developed by Henriques et *** explore the formation and evolution of massive galaxies(MGs,stellar-mass M*>1011 M⊙).Different from previous works,we focus on the ones just formed(*** reach?1011 M⊙).We find that most of the MGs are formed around z=0.6,with the earliest formation at z>***,although most of the MGs in the local Universe are passive,we find that only 13%of the MGs are quenched at the formation *** of the quenched MGs at formation already host a very massive supermassive black hole(SMBH)which could power the very effective AGN *** the star-forming MGs,the ones with more massive SMBH prefer to quench in shorter timescales;in particular,those with MSMBH>107.5 M⊙have a quenching timescale of~0.5 Gyr and the characteristic MSMBH depends on the chosen stellar mass threshold in the definition of MGs as a result of their *** also find that the"in-situ"star formation dominates the stellar mass growth of MGs until they are *** the whole redshift range,we find the quiescent MGs prefer to stay in more massive dark matter halos,and have more massive SMBH and less cold gas *** results provide a new angle on the whole life of the growth of MGs in the Universe.

关键词： galaxies:evolution galaxies:formation galaxies:star formation galaxies:high-redshift methods:numerical

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Submerged Sequencing-Batch Membrane Bioreactor and Mechanisms for the proessing of coke wastewater

Submerged Sequencing-Batch Membrane Bioreactor and Mechanism...

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The 12th Asian Pacific Confederation of Chemical Engineering Congress

作者： Wen-ying Li jing-Wen Wu Bao-jie Zhao jie-ying jing Key Laboratory of Coal Sdence and Technology for Ministry of Education and Shanxi Province,Taiyuan University of Technology,030024,China

This research describes COD and NH-N removal of coke wastewater using a laboratory scale Submerged Sequencing Batch Membrane *** reactor was fed with coke wastewater in descending dilution multiples until finally orig... 详细信息

关键词： coke wastewater treatment submerged sequencing batch membrane biorector COD removal ammonia nitrogen removal mechanisms

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由NOPA产生高质量明亮压缩光及明亮EPR光束

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物理学报 2002年第5期51卷 966-972页

作者：李小英荆杰泰张靖潘庆谢常德彭堃墀量子光学与光量子器件国家重点实验室山西大学光电研究所太原030006

通过非简并光学参量放大器获得了明亮双模正交压缩光及明亮EPR光束 .实验测得明亮耦合模的正交振幅压缩为 5 7± 0 2dB ;信号模与闲置模的正交振幅和 (正交位相差 )的起伏低于散粒噪声极限 5 4± 0 2dB(5 4± 0 2dB) ,EPR关联的... 详细信息

通过非简并光学参量放大器获得了明亮双模正交压缩光及明亮EPR光束 .实验测得明亮耦合模的正交振幅压缩为 5 7± 0 2dB ;信号模与闲置模的正交振幅和 (正交位相差 )的起伏低于散粒噪声极限 5 4± 0 2dB(5 4± 0 2dB) ,EPR关联的乘积为 0 332± 0 0 0 3.

关键词：明亮双模正交压缩光明亮EPR光束非简并光学参量放大器压缩态光场量子光学 NOPA 高质量明亮压缩光

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Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

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Neural Regeneration Research 2025年第8期20卷 2373-2381页

作者： Lifang Zhao Mingkai Zhang Qimeng Li Xuemin Wang jie Lu ying Han Yanning Cai Department of Clinical Biobank Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Geriatric Medical Research Center BeijingChina Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijingChina Department of Radiology and Nuclear Medicine Xuanwu HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics BeijingChina Key Laboratory of Neurodegenerative diseases Ministry of EducationBeijingChina School of Biomedical Engineering Hainan UniversityHaikouHainan ProvinceChina Center of Alzheimer’s Disease Beijing Institute for Brain DisordersBeijingChina National Clinical Research Center for Geriatric Diseases BeijingChina Institute of Biomedical Engineering Shenzhen Bay LaboratoryGaoke Innovation CenterShenzhenGuangdong ProvinceChina Department of Neurobiology Xuanwu HospitalCapital Medical UniversityBeijingChina

Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative ***,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°*** aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large *** samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline *** samples were stored at-80°C for up to 6 years before being used in this *** results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage ***,the level of total tau showed a negative correlation with sample storage ***,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage *** was not observed in individuals with cognitive ***,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage ***,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's ***,in cohort studies,it is important to consider the impact of storage time on the overall results.

关键词： Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein neurodegeneration neurofilament light chain plasma biomarkers single molecule array storage time tau

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A Semi-automatic Method Based on Statistic for Mandarin Semantic Structures Extraction in Specific Domains

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Journal of Shanghai Jiaotong university(Science) 2004年第4期9卷 25-29页

作者：熊英朱杰孙静 Dept. of Electronic Eng. Shanghai Jiaotong Univ. Shanghai 200030 China

This paper proposed a new method of semi-automatic extraction for semantic structures from unlabelled corpora in specific domains. The approach is statistical in nature. The extracted structures can be used for shallow parsing and semantic labeling. By iteratively extracting new words and clustering words, we get an inital semantic lexicon that groups words of the same semantic meaning together as a class. After that, a bootstrapping algorithm is adopted to extract semantic structures. Then the semantic structures are used to extract new

关键词： and augment the semantic lexicon. The resultant semantic structures are interpreted by persons and are amenable to hand-editing for refinement. In this experiment the semi-automatically extracted structures S SA provide recall rate of 84.

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Effects of the extrusion parameters on microstructure,texture and room temperature mechanical properties of extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 136-146页

作者： Chenjin Zhang Guangyu Yang Lei Xiao Zhiyong Kan jing Guo Qiang Li Wanqi jie State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China College of Materials Science and Engineering Fuzhou UniversityFuzhou 350108China College of Chemistry and Environmental Science Qujing Normal UniversityQujing 655011China

Microstructure,texture,and mechanical properties of the extruded Mg-2.49Nd-1.82Gd-0.2Zn-0.2Zr alloy were investigated at different extrusion temperatures(260 and 320℃),extrusion ratios(10:1,15:1,and 30:1),and extrusion speeds(3 and 6 mm/s).The experimental results exhibited that the grain sizes after extrusion were much finer than that of the homogenized alloy,and the second phase showed streamline distribution along the extrusion direction(ED).With extrusion temperature increased from 260 to 320℃,the microstructure,texture,and mechanical properties of alloys changed *** dynamic recrystallization(DRX)degree and grain sizes enhanced as the extrusion ratio increased from 10:1 to 30:1,and the strength gradually decreased but elongation(EL)*** the extrusion speed increased from 3 to 6 mm/s,the grain sizes and DRX degree increased significantly,and the samples presented the typical-rare-earth(RE)*** alloy extruded at 260℃ with extrusion ratio of 10:1 and extrusion speed of 3 mm/s showed the tensile yield strength(TYS)of 213 MPa and EL of 30.6%.After quantitatively analyzing the contribution of strengthening mechanisms,it was found that the grain boundary strengthening and dislocation strengthening played major roles among strengthening *** results provide some guidelines for enlarging the industrial application of extruded Mg-RE alloy.

关键词： Mg-rare earth alloys extrusion temperature extrusion ratio extrusion speed strengthening mechanisms

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基于灰色关联分析与RBF神经网络的土壤浸提液电导率预测

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节水灌溉 2009年第7期 15-17,20页

作者：马亮马英杰赵经华新疆农业大学水利与土木工程学院新疆乌鲁木齐830052

采用灰色系统理论中的关联分析方法,对影响土壤浸提液电导率的主要盐分离子类型进行分析,挑选出影响土壤浸提液电导率的主要因素。与此同时,介绍了径向基函数(RBF)神经网络的原理、训练算法,并建立了基于RBF神经网络与灰色关联分析的土... 详细信息

采用灰色系统理论中的关联分析方法,对影响土壤浸提液电导率的主要盐分离子类型进行分析,挑选出影响土壤浸提液电导率的主要因素。与此同时,介绍了径向基函数(RBF)神经网络的原理、训练算法,并建立了基于RBF神经网络与灰色关联分析的土壤浸提液电导率预测模型。结果表明,所建模型具有较强的非线性处理能力和逼近能力,运算速度快、性能稳定,预测精度较高,可以应用于生产实践中。

关键词：灰色关联分析电导率 RBF神经网络

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miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong jing-jing Hu Yan Yu Xiao-Li Li Xiao-Ting Sun Li-Ting Wang Xia Wu Ling-jie Zhu Xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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Unraveling the mechanism of action of Shangxia Liangji formula for treating insomnia:a metabolomics and network pharmacology approach

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Traditional Medicine Research 2025年第2期10卷 16-29页

作者： Xia-jie Quan Hao Liang Yong-Hong Tang Li Jiang Xiong-ying Ji Feng-ying Zhang Ping Zhang Bo Ouyang Department of Information The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Neurology The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Gastroscopy The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China Department of Traditional Chinese Medicine The Affiliated Nanhua HospitalHengyang Medical SchoolUniversity of South ChinaHengyang 421002China

Background:Insomnia is a prevalent clinical condition and Shangxia Liangji formula(SXLJF)is a well-established method of ***,the specific mechanism of action of SXLJF remains ***:The mouse model of insomnia was established by intraperitoneal injection of ***-two mice were randomly divided into a negative control group,model group,SXLJF group(18.72 g/kg/day),and positive control group(diazepam,2 mg/kg)and treated with the corresponding drugs for 7 consecutive *** open field test and pentobarbital-induced sleeping test were ***-MS-based untargeted metabolomics and network pharmacology were applied to explore the potential targets of SXLJF for treating ***,key targets were validated using ***:Behavioral tests demonstrated that SXLJF reduced the total distance,average velocity,central distance,and sleep latency,and prolonged sleep *** and network pharmacology revealed potential targets,signaling pathways,metabolic pathways,and metabolites associated with the anti-insomnia effects of ***,tyrosine hydroxylase(TH)and tyrosine metabolism emerged as crucial metabolic pathways and targets,***-qPCR results supported the role of TH in the mechanism of SXLJF in treating ***:In conclusion,TH and tyrosine metabolism may represent significant targets and pathways for SXLJF in treating insomnia.

关键词： Shangxia Liangji formula insomnia metabolomics network pharmacology tyrosine hydroxylase tyrosine metabolism

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浮针疗法治疗早期强直性脊柱炎疗效观察

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上海针灸杂志 2017年第9期36卷 1088-1091页

作者：王英杰丘文静深圳市龙岗中心医院深圳518116 深圳市龙岗区人民医院深圳518172

目的观察浮针疗法对早期强直性脊柱炎的临床疗效及其对肿瘤坏死因子-?(TNF-?)、白介素-1(IL-1)、白介素-6(IL-6)的影响。方法将80例符合纳入标准的早期强直性脊柱炎患者采用随机卡法按1:1分为治疗组和对照组,每组40例。治疗组予单纯浮... 详细信息

目的观察浮针疗法对早期强直性脊柱炎的临床疗效及其对肿瘤坏死因子-?(TNF-?)、白介素-1(IL-1)、白介素-6(IL-6)的影响。方法将80例符合纳入标准的早期强直性脊柱炎患者采用随机卡法按1:1分为治疗组和对照组,每组40例。治疗组予单纯浮针治疗,对照组予塞来昔布胶囊、甲氨蝶呤片、柳氮磺吡啶肠溶片常规治疗,共治疗24星期。观察两组治疗前后Bath AS疾病活动指数(BASDAI)、Bath AS功能指数(BASFI)、腰痛指数、中医证候评分及TNF-?、IL-1、IL-6等指标的变化情况。结果两组治疗后BASDAI、BASFI、腰痛指数、中医证候评分及TNF-?、IL-1、IL-6水平较同组治疗前均有改善(P<0.05),且治疗组治疗后BASDAI、BASFI、腰痛指数、中医证候评分及TNF-?、IL-1、IL-6水平优于对照组(P<0.05)。结论浮针疗法能缓解早期强直性脊柱炎患者临床症状,改善脊柱关节功能且安全性良好,其机制可能与降低炎性细胞因子TNF-?、IL-1、IL-6的水平相关。

关键词：脊柱炎,强直性针刺疗法浮针 BASDAI BASFI

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