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Biomedical and Environmental Sciences 2024年第1期37卷 117-121页

作者： WEN Si Hui LI Lu Bei huang Hui Dan XIE ying LUO Lei Key Laboratory of Molecular Epidemiology of Hunan Province School of MedicineHunan Normal UniversityChangsha 410081HunanChina Department of Occupational Health Changsha Centre for Disease Control and PreventionChangsha 410004HunanChina The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province Hunan Normal University School of MedicineChangsha 410013HunanChina

The pervasive utilization of industrial substances has escalated human exposure to cadmium(Cd),a metal associated with long-term negative health outcomes such as renal dysfunction,neurological disorders,and various cancers^([1]).Once ingested by humans,Cd interacts with cysteine-rich metallothioneins(MTs)which have metal-binding and antioxidant properties and is subsequently transported to the kidney^([2]).

关键词： Renal kidney cadmium

Non-Existence of Entire Solution of a Type of System of Equations

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Journal of Mathematical Research with Applications 2024年第2期44卷 213-224页

作者： Zhiwei ZHOU ying ZHANG Zhigang huang School of Mathematics Suzhou University of Science and Technology Information Construction and Management Center Suzhou University of Science and Technology

In this paper, we will prove that the system of differential-difference equations■ has no transcendental entire solution(f(z), g(z)) with ρ(f, g) < ∞ such that λ(f) < ρ(f) andλ(g) < ρ(g), where P1(z), Q1(z), P2... 详细信息

关键词： transcendental entire function finite order system of differential-difference equations

The Review of Land Use/Land Cover Mapping AI Methodology and Application in the Era of Remote Sensing Big Data

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Journal of Geodesy and Geoinformation Science 2024年第3期7卷 1-23页

作者： ZHANG Xinchang SHI Qian SUN ying huang Jianfeng HE Da College of Geography and Remote Sensing Sciences Xinjiang UniversityUrumqi 830017China School of Geography and Remote Sensing Guangzhou UniversityGuangzhou 510006China School of Geography and Planning Sun Yat-sen UniversityGuangzhou 510006China School of Atmospheric Sciences Sun Yat-sen UniversityZhuhai 519082China

With the increasing number of remote sensing satellites,the diversification of observation modals,and the continuous advancement of artificial intelligence algorithms,historically opportunities have been brought to the applications of earth observation and information retrieval,including climate change monitoring,natural resource investigation,ecological environment protection,and territorial space *** the past decade,artificial intelligence technology represented by deep learning has made significant contributions to the field of Earth ***,this review will focus on the bottlenecks and development process of using deep learning methods for land use/land cover mapping of the Earth’s ***,it introduces the basic framework of semantic segmentation network models for land use/land cover ***,we summarize the development of semantic segmentation models in geographical field,focusing on spatial and semantic feature extraction,context relationship perception,multi-scale effects modelling,and the transferability of models under geographical ***,the application of semantic segmentation models in agricultural management,building boundary extraction,single tree segmentation and inter-species classification are ***,we discuss the future development prospects of deep learning technology in the context of remote sensing big data.

关键词： remote sensing big data deep learning semantic segmentation land use/land cover mapping

Measuring drug similarity using drug–drug interactions

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Quantitative Biology 2024年第2期12卷 164-172页

作者： Ji Lv Guixia Liu Yuan Ju Houhou huang ying Sun College of Computer Science and Technology Jilin UniversityChangchunChina Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin UniversityChangchunChina Sichuan University Library Sichuan UniversityChengduChina College of Chemistry Jilin UniversityChangchunChina Department of Respiratory Medicine The First Hospital of Jilin UniversityChangchunChina

Combination therapy is a promising approach to address the challenge of antimicrobial resistance,and computational models have been proposed for predicting drug–drug *** existing models rely on drug similarity measures based on characteristics such as chemical structure and the mechanism of *** this study,we focus on the network structure itself and propose a drug similarity measure based on drug–drug interaction *** explore the potential applications of this measure by combining it with unsupervised learning and semi-supervised learning *** unsupervised learning,drugs can be grouped based on their interactions,leading to almost monochromatic group–group *** addition,drugs within the same group tend to have similar mechanisms of action(MoA).In semi-supervised learning,the similarity measure can be utilized to construct affinity matrices,enabling the prediction of unknown drug–drug *** method exceeds existing approaches in terms of ***,our experiments demonstrate the effectiveness and practicability of the proposed similarity *** the one hand,when combined with clustering algorithms,it can be used for functional annotation of compounds with unknown *** the other hand,when combined with semi-supervised graph learning,it enables the prediction of unknown drug–drug interactions.

关键词： drug similarity drug–drug interactions drug combinations synergy effect clustering semi-supervised learning

Interpenetrating network-reinforced gel polymer electrolyte for ultra-stable lithium−iodine batteries

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Carbon Energy 2024年第6期6卷 234-247页

作者： ying Jiang Peng huang Minman Tong Bingxin Qi Tao Sun Zhongyun Xian Wen Yan Chao Lai School of Chemistry and Materials Science Jiangsu Normal UniversityXuzhouJiangsuChina

Li-I_(2) batteries have attracted much interest due to their high capacity,exceptional rate performance,and low *** so,the problems of unstable Li anode/electrolyte interface and severe polyiodide shuttle in Li-I_(2) batteries need to be ***,the interfacial reactions on the Li anode and I_(2) cathode have been effectively optimized by employing a well-designed gel polymer electrolyte strengthened by cross-linked Ti-O/Si-O(GPETS).The interpenetrating network-reinforced GPETS with high ionic conductivity(1.88×10^(-3)S cm^(-1)at 25℃)and high mechanical strength endows uniform Li deposition/stripping over 1800 h(at 1.0mA cm^(-2),with a plating capacity of 3.0mAh cm^(-2)).Moreover,the GPETS abundant in surface hydroxyls is capable of capturing soluble polyiodides at the interface and accelerating their conversion kinetics,thus synergistically mitigating the shuttle *** from these properties,the use of GPETS results in a high capacity of 207 mAh g^(-1)(1 C)and an ultra-low fading rate of 0.013%per cycle over 2000 cycles(5 C).The current study provides new insights into advanced electrolytes for Li-I_(2) batteries.

关键词： electrode/electrolyte interface gel polymer electrolytes lithium dendrites lithium−iodine batteries polyiodide shuttle

Chemical derivatization strategies for enhancing the HPLC analytical performance of natural active triterpenoids

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Journal of Pharmaceutical Analysis 2024年第3期14卷 295-307页

作者： Xiao-Feng huang ying Xue Li Yong Tian-Tian Wang Pei Luo Lin-Sen Qing chengdu Institute of Biology Chinese Academy of SciencesChengdu610041China State Key Laboratory for Quality Research in Chinese Medicines Macao University of Science and TechnologyMacaoChina Sichuan Center for Disease Control and Prevention Chengdu610041China University of Chinese Academy of Sciences Beijing100049China

Triterpenoids widely exist in nature,displaying a variety of pharmacological *** triterpenoids in different matrices,especially in biological samples holds great ***-performance liquid chromatography(HPLC)has become the predominant method for triterpenoids analysis due to its exceptional analytical ***,due to the structural similarities among botanical samples,achieving effective separation of each triterpenoid proves challenging,necessitating significant improvements in analytical ***,triterpenoids are characterized by a lack of ultraviolet(UV)absorption groups and chromophores,along with low ionization efficiency in mass ***,routine HPLC analysis suffers from poor *** derivatization emerges as an indispensable technique in HPLC analysis to enhance its *** the structural characteristics of triterpenoids,various derivatization reagents such as acid chlorides,rhodamines,isocyanates,sulfonic esters,and amines have been employed for the derivatization analysis of *** review comprehensively summarized the research progress made in derivatization strategies for HPLC detection of ***,the limitations and challenges encountered in previous studies are discussed,and future research directions are proposed to develop more effective derivatization methods.

关键词： Triterpenoid HPLC Derivatization Quantification

Immediate Effect of Electro-acupuncture on Endometrial Blood Flow in Patients with Recurrent Implantation Failure:A Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第4期30卷 291-298页

作者： LAI Yuan-yuan LIU Li-ying WU Yong-na huang Lei ZHENG Xiao-yan GAN Di YU Si-yi ZHONG ying LIANG Fan-rong ZHOU ying YANG Jie Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu(610032)China Sichuan Jinxin Xi'nan Women's and Children's Hospital Chengdu(610032)China Yuan TCM Wellness Pte.Ltd.(999002) Pulse TCM SingaporeSingapore

Objective To investigate the immediate effects of electro-acupuncture(EA)on endometrial blood flow among recurrent implantation failure(RIF)*** Eighty RIF patients,enrolled from March 2022 to December 2022,were randomly allocated into either the EA group(40 cases)or the waiting-list(WL)group(40 cases)by using a random number *** EA group underwent acupuncture at points of Shenting(GV 24),Baihui(GV 4),Benshen(GB 13),bilateral Zigong(EX-CA 1),huangshu(KI 16),Sanyinjiao(SP 6)and Xuehai(SP10),and electric acupuncture apparatus was connected to EX-CA 1,KI 16,SP 6,and SP 10 with disperse-dense waves at 4/20 Hz frequencies for 30 min after transvaginal ultrasound,while the WL group received no *** primary outcome measured was the endometrial volume blood *** secondary outcomes included the bilateral uterine artery index,endometrial volume,endometrial blood flow type,vascular distribution index(VI^(MV))for endometrial and ovary,clinical pregnancy rate,and embryo implantation *** In the EA group,there was a notable decrease in the bilateral pulsatility index and a significant improvement in the endometrial blood flow type post-EA(P0.05).Besides,no adverse events related to EA were *** EA can promptly ameliorate VI^(MV) for the endometrial and right ovary,and endometrial blood flow *** randomized controlled trials are warranted to investigate the long-term effects of EA on blood flow of RIF patients and its implications for pregnancy outcomes.(Trial registration ***2200057377

关键词： electro-acupuncture recurrent implantation failure transvaginal ultrasound endometrial receptivityanalysis randomized controlledtrial

Geochemistry and origins of hydrogen-containing natural gases in deep Songliao Basin,China:Insights from continental scientific drilling

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Petroleum Science 2024年第2期21卷 741-751页

作者： Shuang-Biao Han Chao-Han Xiang Xin Du Lin-Feng Xie Jie huang cheng-Shan Wang College of Geoscience and Surveying Engineering China University of Mining and TechnologyBeijing100083China State Key Laboratory of Biogeology and Environmental Geology China University of GeosciencesBeijing100083China

The different reservoirs in deep Songliao Basin have non-homogeneous lithologies and include multiple layers with a high content of hydrogen *** gas composition and stable isotope characteristics vary significantly,but the origin analysis of different gas types has previously been *** on the geochemical parameters of gas samples from different depths and the analysis of geological settings,this research covers the diverse origins of natural gas in different *** gas components are mainly methane with a small amount of C_(2+),and non-hydrocarbon gases,including nitrogen(N_(2)),hydrogen(H_(2)),carbon dioxide(CO_(2)),and helium(He).At greater depth,the carbon isotope of methane becomes heavier,and the hydrogen isotope points to a lacustrine sedimentary *** increasing depth,the origins of N_(2)and CO_(2)change gradually from a mixture of organic and inorganic to *** origins of hydrogen gas are complex and include organic sources,water radiolysis,water-rock(Fe^(2+)-containing minerals)reactions,and *** shales of Denglouku and Shahezi Formations,as source rocks,provide the premise for generation and occurrence of organic ***,the deep faults and fluid activities in Basement Formation control the generation and migration of mantle-derived *** discovery of a high content of H_(2)in study area not only reveals the organic and inorganic association of natural-gas generation,but also provides a scientific basis for the exploration of deep hydrogen-rich gas.

关键词： Gas compositions Stable isotopes Gas origins Hydrogen gas Songliao Basin

Orientational growth behavior and mechanism of delta(δ)phase precipitation in cold-rolled Inconel 718 alloy during heat treatment

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Journal of Iron and Steel Research International 2024年第1期31卷 264-274页

作者： Neng-yong Ye Guang-liang Zhang Tian-yue huang Ming cheng Shi-hong Zhang Lei Wang School of Materials Science&Engineering Taizhou UniversityTaizhou318000ZhejiangChina Institute of Metal Research Chinese Academy of SciencesShenyang110016LiaoningChina

Due to the important role ofδphase's quantity and morphology in the mechanical and fatigue properties of Inconel 718 alloy and its components,it is necessary to renew insights into the effect of cold deformation on theδphase precipitation,especially on the morphology ***,the nucleation and growth behavior ofδphase in cold-rolled Inconel 718 alloy during aging were *** results show that the precipitation rate and volume fraction ofδphase increase with increasing the cold rolling reduction from 10%to 50%.The volume fraction ofδphase reaches equilibrium after 5 h,remaining at 5.98%,6.52%,and 6.79%under different rolling reductions(10%,30%,and 50%),*** nucleation ofδphase mainly occurs on different sites(grain boundaries,new twin boundaries and old twin boundaries)under 10%rolling reduction,whileδphase mainly nucleates on the new grain boundaries of static recrystallization due to 50%rolling *** the growth ofδphase undergoes a process of alternate orientation growth from spherical(nucleation)→short rod(longitudinal orientation growth)→short rod(radial orientation growth)→dynamic *** 10%rolling reduction,δphase tends to grow into the matrix,while under 50%rolling reduction,the orientation grows faster and is easily affected by the grain boundary curvature.

关键词： Inconel 718 alloy Cold rolling δphase Orientation growth Morphology evolution

Study of inter-well interference in shale gas reservoirs by a robust production data analysis method based on deconvolution

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Petroleum Science 2024年第4期21卷 2502-2519页

作者： Wen-Chao Liu cheng-cheng Qiao Ping Wang Wen-Song huang Xiang-Wen Kong Yu-Ping Sun He-Dong Sun Yue-Peng Jia School of Civil and Resource Engineering University of Science and Technology Beijing PetroChina Research Institute of Petroleum Exploration and Development

In order to overcome the defects that the analysis of multi-well typical curves of shale gas reservoirs is rarely applied to engineering, this study proposes a robust production data analysis method based on deconvolution, which is used for multi-well inter-well interference research. In this study, a multi-well conceptual trilinear seepage model for multi-stage fractured horizontal wells was established, and its Laplace solutions under two different outer boundary conditions were obtained. Then, an improved pressure deconvolution algorithm was used to normalize the scattered production data. Furthermore, the typical curve fitting was carried out using the production data and the seepage model solution. Finally,some reservoir parameters and fracturing parameters were interpreted, and the intensity of inter-well interference was compared. The effectiveness of the method was verified by analyzing the production dynamic data of six shale gas wells in Duvernay area. The results showed that the fitting effect of typical curves was greatly improved due to the mutual restriction between deconvolution calculation parameter debugging and seepage model parameter debugging. Besides, by using the morphological characteristics of the log-log typical curves and the time corresponding to the intersection point of the log-log typical curves of two models under different outer boundary conditions, the strength of the interference between wells on the same well platform was well judged. This work can provide a reference for the optimization of well spacing and hydraulic fracturing measures for shale gas wells.

关键词： Shale gas Inter-well interference Deconvolution Production data analysis Typical curves Multi-stage fractured horizontal well