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Comparative transcriptomic and metabolomic analysis reveals pectoralis highland adaptation across altitudinal songbirds

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Integrative Zoology 2022年第6期17卷 1162-1178页

作者： ying xiong Yan HAO Yalin CHENG Liqing FAN Gang SONG Dongming LI Yanhua QU Fumin LEI Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijingChina University of Chinese Academy of Sciences BeijingChina Key Laboratory of Forest Ecology in Tibet Plateau of Ministry of Education Institute of Tibet Plateau EcologyTibet Agriculture&Animal Husbandry UniversityNyingchiChina Key Laboratory of Animal Physiology Biochemistry and Molecular Biology of Hebei ProvinceCollege of Life SciencesHebei Normal UniversityShijiazhuangChina Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunmingChina

Pectoralis phenotypic variation plays a fundamental role in locomotion and thermogenesis in highland ***-ever,its regulatory and metabolic mechanisms remain enigmatic to ***,we integrated phenomic,tran-scriptomic,and metabolomic approaches to determine muscle variation and its underpinning mechanisms across altitudinal *** conﬁrmed that all highland birds had considerable increases in muscle oxidative capacity,capillarity,and mitochondrial abundance in our ***,transcriptomic analyses found that differentially expressed genes in phenotype-associated modules enriched for blood vessel,muscle structure development,and mitochondrial *** similar traits and functional enrichments across highland birds,different mechanisms drove their occurrence in high-altitude tree sparrow and 2 snowﬁ***,a metabolic feature shared by all the 3 highland birds is the improvement in insulin sensitivity and glucose utilization through activating insulin signaling pathway,which is vital to increase muscle oxidative capacity and maintain metabolic ***,fatty acid biosynthesis and oxidation are enhanced in only 2 snowﬁnches which had a long evolutionary history on the high plateau,also differing from ketone body metabolism in recently introduced colonizer of the tree sparrow of the high *** study represents a vital contribution to reveal the regulatory and metabolic basis of pectoralis variation across altitudinal songbirds.

关键词： altitude gas chromatography–mass spectrometry hypoxia pectoralis RNA–seq

Friction compensation design based on state observer and adaptive law for high-accuracy positioning system

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Progress in Natural Science:Materials International 2006年第2期16卷 147-152页

作者： WANG ying, xiong Zhenhua and DING Han (School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China) School of Mechanical Engineering Shanghai Jiao Tong University Shanghai 200030 China

Friction is one of the main factors that affect the positioning accuracy of motion system. Friction compensation based on friction model is usually adopted to eliminate the nonlinear effect of friction. This paper presents a proportional-plus-derivative (PD) feedback controller with a friction compensator based on LuGre friction model. We also design a state observer to observe the unknown state of LuGre friction model, and adopt a parameter adaptive law and off-line approximation to estimate the parameters of LuGre friction model. Comparative experiments are carried out among our proposed controller, PD controller with friction compensation based on classical friction model, and PD controller without friction compensation. Experimental results demonstrate that our proposed controller can achieve better performance, especially higher positioning accuracy.

关键词： friction compensation state observer adaptive law linear motor motion control.

Computerized lung sound analysis following clinical improvement of pulmonary edema due to congestive heart failure exacerbations

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Chinese Medical Journal 2010年第9期123卷 1127-1132页

作者： WANG Zhen xiong ying-xia Department of Emergency Medicine Beijing Shijitan HospitalBeijing 100038China

Background Although acute congestive heart failure （CHF） patients typically present with abnormal auscultatory findings on lung examination, lung sounds are not normally subjected to rigorous analysis. The goals of this study were to use a computerized analytic acoustic tool to evaluate lung sound patterns in CHF patients during acute exacerbation and after clinical improvement and to compare CHF profiles with those of normal *** Lung sounds throughout the respiratory cycle was captured using a computerized acoustic-based imaging technique. Thirty-two consecutive CHF patients were imaged at the time of presentation to the emergency department and after clinical improvement. Digital images were created, geographical area of the images and lung sound patterns were quantitatively *** The geographical areas of the vibration energy image of acute CHF patients without and with radiographically evident pulmonary edema were （67.9±4.7） and （60.3±3.5） kilo-pixels, respectively （P 〈0.05）. In CHF patients without and with radiographically evident pulmonary edema （REPE）, after clinical improvement the geographical area of vibration energy image of lung sound increased to （74.5±4.4） and （73.9±3.9） kilo-pixels （P 〈0.05）, respectively. Vibration energy decreased in CHF patients with REPE following clinical improvement by an average of （85±19）% （P 〈0.01）. Conclusions With clinical improvement of acute CHF exacerbations, there was more homogenous distribution of lung vibration energy, as demonstrated by the increased geographical area of the vibration energy image. Lung sound analysis may be useful to track in acute CHF exacerbations.

关键词： lung sounds vibration energy of lung sound exacerbation congestive heart failure

Oxidation behavior of high Hf nickel-based superalloy in air at 900, 1000 and 1100℃

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International Journal of Minerals,Metallurgy and Materials 2021年第12期28卷 1957-1965页

作者： Jiu-han Xiao ying xiong Li Wang Xiang-wei Jiang Dong Wang Kai-wen Li Jia-sheng Dong Lang-hong Lou Shi-Changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China China National South Aviation Industry Company Limited Zhuzhou 412002China

To investigate the oxidation behavior of a nickel-based superalloy with high hafnium content(1.34 wt%),this study performed isothermal oxidation tests at 900,1000,and 1100℃for up to 200 h.X-ray diffraction and scanning electron microscopy with energy-dispersive X-ray spectroscopy were applied to study the oxidation *** weight gain of the high Hf nickel-based superalloy exhibited a parabolalike curve,and no spallation of the oxide scale was observed during the oxidation *** alloy presented excellent oxidation resistance,and no HfO_(2) was observed in the oxide scale at 900℃.With the increase of the oxidation temperature to 1000℃,HfO_(2) particles formed in the spinel phases of the scale,and"peg-like"HfO_(2) was observed within and beneath the inner layer of Al2O_(3) after *** the oxidation temperature rose to 1100℃,"peg-like"HfO_(2) was observed at the early stage of the oxidation test(within 25 h).The formation mechanism of HfO_(2) and its impact on oxidation resistance were investigated based on the analysis of the oxidation test results at different temperatures.

关键词： superalloy resistance alloy

Effect of Ni Interlayer on Cavitation Erosion Resistance of NiTi Cladding by Tungsten Inert Gas(TIG)Surfacing Process

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Acta Metallurgica Sinica(English Letters) 2020年第3期33卷 415-424页

作者： Zhen-Ping Shi Zheng-Bin Wang Ji-Qiang Wang Yan-Xin Qiao Huai-Ning Chen Tian-ying xiong Yu-Gui Zheng CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

The NiTi cladding with/without Ni interlayer was prepared on stainless steel(SS) by tungsten inert gas(TIG) surfacing process,aiming at achieving good cavitation erosion *** ranking according to the cavitation erosion resistance is NiTi plate> NiTi-Ni-TIG cladding> NiTi-TIG cladding> *** better cavitation erosion resistance of NiTi-TIG and NiTi-Ni-TIG claddings than SS substrate is due to their higher micro-hardness and ***,the existence of Ni interlayer can decrease the amount of brittle intermetallic compounds,such as Fe2 Ti,and inhibit the crack generation,which results in the higher cavitation erosion resistance of NiTi-Ni-TIG compared with NiTi-TIG ***,the cavitation erosion resistance of NiTi cladding prepared by TIG surfacing process can be improved by employing Ni interlayer.

关键词： Cavitation erosion NiTi Cladding Tungsten inert gas surfacing process Ni interlayer

Numerical simulations of supercritical carbon dioxide fracturing:A review

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第7期15卷 1895-1910页

作者： Lin Wu Zhengmeng Hou Zhifeng Luo ying xiong Nanlin Zhang Jiashun Luo Yanli Fang Qianjun Chen Xuning Wu Institute of Subsurface Energy Systems Clausthal University of TechnologyClausthal-Zellerfeld38678Germany b State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500China

As an emerging waterless fracturing technology,supercritical carbon dioxide(SC-CO_(2))fracturing can reduce reservoir damage and dependence on water resources,and can also promote the reservoir stimulation and geological storage of carbon dioxide(CO_(2)).It is vital to figure out the laws in SC-CO_(2)fracturing for the large-scale field implementation of this *** paper reviews the numerical simulations of wellbore flow and heat transfer,fracture initiation and propagation,and proppant transport in SC-CO_(2)fracturing,including the numerical approaches and the obtained *** shows that the variations of wellbore temperature and pressure are complex and strongly *** wellhead pressure can be reduced by tubing and annulus co-injection or adding drag reducers into the fracturing *** the temperature of CO_(2)with wellhead heating can promote CO_(2)to reach the well bottom in the supercritical *** with hydraulic fracturing,SC-CO_(2)fracturing has a lower fracture initiation pressure and can form a more complex fracture network,but the fracture width is *** technology of SC-CO_(2)fracturing followed by thickened SC-CO_(2)fracturing,which combines with high injection rates and ultra-light proppants,can improve the placement effect of proppants while improving the complexity and width of *** follow-up research is required to get a deeper insight into the SC-CO_(2)fracturing mechanisms and develop cost-effective drag reducers,thickeners,and ultra-light *** paper can guide further research and promote the field application of SC-CO_(2)fracturing technology.

关键词： Wellbore Fracturing Proppant transport Supercritical carbon dioxide Fracture initiation and propagation

Experimental study of destruction to porcine spleen in vivo by microwave ablation

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World Journal of Gastroenterology 2011年第45期17卷 5014-5020页

作者： Fei Gao Yang-Kui Gu Jing-Xian Shen Chang-Lun Li xiong-ying Jiang Jin-Hua Huang State Key Laboratory of Oncology in South China Guangzhou 510060 Guangdong Province China Medical Imaging and Interventional Center Cancer Center Sun Yat-sen University Guangzhou 510060 Guangdong Province China

AIM: To discuss the safety, feasibility and regularity of destruction to porcine spleen in vivo with congestion and tumescence by microwave ablation (MWA). METHODS: Ligation of the splenic vein was used to induce congestion and tumescence in vivo in five porcine spleens, and microwave ablation was performed 2-4 h later. A total of 56 ablation points were ablated and the ablation powers were 30-100 W. The ablation time (1, 2, 3, 4, 5, 6, 7, 8, 9 and 10 min) was performed at a power of 60 W. After ablation, the ablation size was measured in pigs A, C, D and E and spleen resection. In pig B, the ablation size was measuredand 2 ablation points were sent for pathology analysis and all tissues were sutured following ablation. Pig B was killed 1 wk later and the ablation points were sent for pathology analysis. Bleeding, tissue carbonization surrounding electrodes, and pathological changes were observed, and the effect on destruction volume relative to different ablation powers, times and positions was analyzed. RESULTS: The incidence of bleeding (only small amounts, < 20 mL) in the course of ablation was 5.4% (3/56) and was attributed to tissue carbonization surrounding electrodes, which also exhibited an incidence of 5.4% (3/56). The destruction volume was influenced by different ablation powers, times and points. It showed that the ablation lesion size increased with increased ablation time, from 1 to 10 min, when the ablation power was 60 W. Also, the ablation lesion size increased with the increase of ablation power, ranging from 30 to 100 W when the ablation time was set to 3 min. A direct correlation was seen between the destruction volume and ablation time by the power of 60 W (r = 0.97542, P < 0.0001, and also between the destruction volume and ablation powers at an ablation time of 3 min (r = 0.98258, P < 0.0001). The destruction volume of zone Ⅱ (the extra-2/3 part of the spleen, relative to the fi rst or second class vascular branches), which was near the hilum

关键词： Experimental study Microwave ablation Porcine spleen In vivo Water-cooled antenna

Endoscopic trans-esophageal submucosal tunneling surgery:A new therapeutic approach for diseases located around the aorta ventralis

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World Journal of Gastroenterology 2019年第1期25卷 85-94页

作者： ying xiong Qian-Qian Chen Ning-Li Chai Shun-Chang Jiao En-Qiang Ling Hu Department of Gastroenterology and Hepatology Chinese PLA General HospitalBeijing 100853China Department of Gastroenterology and Hepatology No.1 Central Hospital of BaodingBaoding 071000Hebei ProvinceChina Department of Oncology Chinese PLA General HospitalBeijing 100853China

AIM To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery(EESTS) technique for diseases located around the aorta *** Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotomy was created. Third, an endoscope was entered into the abdominal cavity through a muscle incision and the endoscope was around the aorta ventralis. Eventually,celiac trunk ganglion neurolysis, partial hepatectomy and splenectomy, partial tissue resection in the area of the posterior peritoneum, and endoscopic submucosal dissection(ESD) combined with lymph node dissection were performed. The animals were given antibiotics for 5 d and necropsied 7 d after *** In all surgeries, one pig died from intraperitoneal hemorrhage after doing partial splenectomy, while the other pigs were alive after successfully operating other surgeries. For surgery of celiac trunk ganglion damage, at necropsy, there was no exudation in the abdominal cavity. Regarding surgery of partial hepatectomy, the wound with part healing was observed in the left hepatic lobe, and no bleeding or obvious exudation was seen. In surgery of partial splenectomy, massive hemorrhage was observed on the splenic wound surface, and the metal clips could not stop bleeding. After surgery of retroperitoneal tissue resection, mild tissue adhesion was observed in the abdominal cavity of one animal, and another one suffered from severe infection. For surgery of ESD and lymph node dissection, a moderate tissue adhesion was *** EESTS is a feasible and safe technique for diseases located around the aorta ventralis.

关键词： Endoscopic trans-esophageal submucosal tunneling surgery Diseases around the aorta ventralis Endoscopic submucosal tunneling technique Abdominal surgery Animal model

Optimization research on supply and demand system for water resources in the Chang-Zhu-Tan urban agglomeration

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Journal of Geographical Sciences 2015年第11期25卷 1357-1376页

作者： xiong ying LI Jingzhi JIANG Dingling Department of Resources and Environmental Sciences Changsha University of Science and TechnologyChangsha 410114 China Research Center of Resource Environment and Urban Planning Changsha University of Science & Tech-nology Changsha 410114 China

Using system analysis theory and methods, a dynamic model of a water resource supply and demand system was built to simulate trends in the supply and demand of water in the Changsha-Zhuzhou-Xiangtan （Chang-Zhu-Tan） urban agglomeration for the period 2012 to 2030. Four scenarios were examined; namely, a traditional development model, an economic development model, a water-saving model, and a coordinated development model. （i） The problem of balancing water resource supply and demand is becoming increasingly conspicuous with a growing population and a rapidly developing economy. （ii） By 2030, water demand is set to reach a total of 105.1 × 10^8 m^3, with a water supply of 5.4 × 10^8 m^3. A coordinated development model for water resource supply could meet the growing demands of socio-economic development, and generate huge comprehensive benefits. This will be the best solution for the development and utilization of a water resource supply and demand system in the Chang-Zhu-Tan urban agglomeration. （iii） We should accelerate the construction of water conservation projects, strengthen the management of water conservation, optimize economic structures, enhance our awareness of the importance of protecting water resources, hasten the recycling of waste water and environmental improvement, and promote utilization efficiency, and support the capabilities of water resources to meet our expectations.

关键词： water resource supply and demand system analog simulation optimization decision-making system dynamics Chang-Zhu-Tan (Changsha-Zhozhoa-Xiangtan) urban agglomeration