检索结果-南通市图书馆

Pulp health and calcific healing of a complicated crown–root fracture with additional root fracture in a maxillary incisor: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第3期13卷 42-49页

作者： Na Li Yue-Yue Ren ying Tang Qi yang tian-tian Meng song Li Jing Zhang Stomatological Hospital and College Anhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Endodontics The Affiliated Stomatological Hospital of Xuzhou Medical UniversityXuzhou 221000Jiangsu ProvinceChina

BACKGROUND Complicated crown–root fracture (CRF) involves severe injury to the crown, root,and pulp, and may be accompanied by multiple root fractures. The loss of a toothhas lifelong consequences for children and teenagers, but the maintenance of pulphealth and the calcific healing of multiple root fractures are rarely reported in *** SUMMARY This case reports healing of a permanent tooth with complicated crown–root andadditional root fractures, in which pulp health was maintained. A 10-year-old girlfell and fractured the root of her maxillary left central incisor at the cervical *** the coronal fragment was repositioned, the tooth was splinted until thetooth was no longer mobile, 2 years later. Eight years after treatment, the toothhas remained asymptomatic with vital pulp and localized gingival ***-beam computed tomography revealed not only calcified healing of the CRFbut also spontaneous healing in an additional undiagnosed root fracture. Thefracture line on the enamel could not be healed by hard tissue and formed agroove in the cervical crown. It was speculated that the groove was related to thelocalized gingival *** This case provides a clinical perspective of the treatment of a tooth with acomplicated CRF and an additional root fracture.

关键词： Complicated crown-root fracture Multiple root fracture Spontaneous healing Cone-beam computed tomography Long-term follow-up Case report

Separation of the ionospheric and thermospheric contributions in the data from the Triple Ionosophere Photo Meter onboard the Feng-Yun 3E satellite

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Earth Sciences 2025年第1期68卷 172-184页

作者： Fang JIANG tian MAO Jin-song WANG Xiu-Qing HU Xiao-Xin ZHANG Liping FU Nan JIA tianfang WANG National Space Science Center Chinese Academy of Sciences Beijing Key Laboratory of Space Environment Exploration Key Laboratory of Environmental Space Situation Awareness Technology National Satellite Meteorological Center China Meteorological Administration

The Triple Ionosphere Photo Meter （TRIPM） is a far ultraviolet nadir-view photometer that is onboard the secondgeneration,polar-orbiting Chinese meteorological satellite Feng-Yun 3E （FY-3E）,which was launched on July 5,*** has three channels,and each is used to measure different types of emissions:（1） 135.6 nm airglow produced by the recombination of the O+ions and electrons in the absence of sunlight （nighttime channel）;（2） 135.6 nm airglow from the OI when sunlight is present （daytime/dusk-dawn 135.6 nm channel）;and （3） Airglow in the N2LBH of the TRIPM （daytime/dusk-dawn N2LBH channel）.FY-3E is a satellite operating in the early morning ***,the data are mostly distributed on the dawndusk side or at times when the solar zenith angle is relatively *** this study,combined with simulation calculations,the data are *** further explore the application value of the data products,a model is used to separate the ionospheric radiative recombination contribution from the thermosphere photoelectron impact excitation contribution in the data from the daytime/dusk-dawn 135.6 nm *** approach not only improves the accuracy of O/N2derived from the 135.6 nm channel and N2LBH channel but also provides the ionospheric 135.6 nm radiance at the same time as the *** results show that the 135.6 nm radiance originating from the combination of O+and electrons extracted from the measurement data exhibits similar equatorial anomaly peak structure characteristics and seasonal variations as the corresponding GPS total electron content （TEC） *** the other hand,the separated 135.6 nm radiance generated from the thermosphere photoelectron collision excitation does not contain radiative recombination contributions;thus,the ionosphere influence is greatly avoided when the O/N2is obtained.

关键词： Far ultraviolet 135.6 nm emission intensity Photoelectron impact excitation Radiative recombination excitation

同方期刊数据库

Deep learning-based end-to-end depth estimation from a single-frame fringe pattern with the FDSUNet++ network

在线全文

学校读者我要写书评

暂无评论

Optoelectronics Letters 2025年

作者： ZHU Xinjun ZHANG Jialei song Limei WANG Hongyi tian Ruiqin School of Artificial Intelligence， tiangong University School of Control Science and Engineering， tiangong University

Recently the depth estimation methods based on deep learning (DL) retains challenging to estimate high-precision in fringe projection structured light three-dimensional (3D) measurement with limited information from a single-frame fringe pattern. In this letter， we proposed a FDSUNet++ convolutional neural network， which consists of a UNet++ base model， an improved squeeze-and-excitation (ISE) block， a Fourier transform (FT) data preprocessing block， and a discrete wavelet transform (DWT) block. The proposed ISE block can improve the ability of feature extraction and the designed FT data preprocessing block preserves the key features of the fringe pattern by Fourier transform. The introduced DWT block reduces the complexity and training cost of the model. By integrating these three blocks into the UNet++ network， it can better achieve depth estimation. Experimental results from two structured light datasets demonstrate that the proposed FDSUNet++ outperforms the state-of-art networks such as UNet， SUNet， R2U-Net， PCTNet and MSUNet++， achieving the best performance in both qualitative and quantitative evaluation.

关键词：

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

鲟鱼育种及新品种选育研究进展

中山大学学报（自然科学版）（中英文） 2025年第1期64卷 93-105页

作者：王巍宋海亮朱华董颖东天胡红霞北京市农林科学院水产科学研究所暨北京市渔业生物技术重点实验室北京100068 农业农村部“鲟鱼遗传育种”重点实验室浙江杭州311799 国家数字种业创新中心北京100097

鲟鱼是鲟形目鱼类的统称。它们不仅具有重要的进化地位,而且具有重要的经济价值。鲟鱼新品种选育研究在近几十年取得了显著进展。本文综述了鲟鱼新品种选育的主要方法,包括杂交育种、雌核发育、性逆转诱导、基因编辑、家系选育、基因组... 详细信息

鲟鱼是鲟形目鱼类的统称。它们不仅具有重要的进化地位,而且具有重要的经济价值。鲟鱼新品种选育研究在近几十年取得了显著进展。本文综述了鲟鱼新品种选育的主要方法,包括杂交育种、雌核发育、性逆转诱导、基因编辑、家系选育、基因组选择和细胞水平育种,讨论了各技术的应用现状,在育种上相关研究和取得的重要突破,并结合我们育种实践积累的经验,展望鲟鱼育种和种业的未来发展,为未来的鲟鱼育种研究提供理论基础和实践指导。

关键词：鲟鱼育种新品种

维普期刊数据库博看期刊

Potential application of radiant floor cooling systems for residential buildings in different climate zones

在线全文

学校读者我要写书评

暂无评论

Building Simulation 2024年第4期17卷 543-560页

作者： Mengying Cui yang song Yudong Mao Kaimin yang Jiying Liu Zhe tian School of Thermal Engineering Shandong Jianzhu UniversityJinan250101China School of Environmental Science and Engineering Tianjin UniversityTianjin300072China Key Lab of Building Environment and Energy of tianjin Tianjin UniversityTianjin300072China

A radiant floor cooling system(RFCS)is a high-comfort and low energy consumption system suitable for residential *** floor systems usually work with fresh air,and their operating performance is affected by climatic *** and outdoor environmental disturbances and the system’s control strategy affect the indoor thermal comfort and energy efficiency of the ***,a multi-story residential building model was established in this *** system simulation program was used to study the operation dynamics of three control strategies of the RFCS based on the calibrated ***,the performance of the control strategies in five climate zones in China were compared using multi-criteria decision-making in *** results show that control strategy has a negligible effect on condensation risk,but the thermal comfort and economic performance differ for different control *** adaptability of different control strategies varies in different climate zones based on the consideration of multiple *** performance of the direct-ground cooling source system is better in Hot summer and warm winter *** variable air volume control strategy scores higher in Serve cold and Temperate zones,and the hours exceeding thermal comfort account for less than 3%of the total simulation ***,it is suggested to choose the RFCS control strategy for residential buildings according to the climate zone characteristics,to increase the energy *** results provide a reliable reference for implementing RFCSs in residential buildings.

关键词： control strategy radiant floor cooling system residential building energy efficiency climate zones

Design and Synthesis of Tri-substituted Chiral Pyrrolidin-2-one Derivatives as CCR4 Antagonists

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2013年第9期31卷 1144-1152页

作者： Wei Sun Linjie tian Hui Qi Dan Jiang ying Wang song Li Junhai Xiao Xiaohong yang School of Pharmaceutical Sciences Jilin University Changchun Jilin 130021 China Laboratory of Computer-Aided Drug Design & Discovery Beijing Institute of Pharmacology & Toxicology Beij'ing 100850 China Center for Human Disease Genomics Peking University Beijing 100083 China

A series of tri-substituted chiral pyrrolidin-2-one derivatives have been designed and synthesized as CC chemokine receptor 4 （CCR4） antagonists. The structure of CCR4 was built by homology modeling. Asymmetric synthesis was applied to synthesize the R,R configuration chiral pyrrolidin-2-one scaffold. The stereoisomeric con- figurations of the compounds were identified by 2D I H-~H COSY spectroscopy and 1D NOESY spectroscopy. This method was more economical and convenient than traditional X-ray single crystal diffraction. In addition, the inter- actions between these compounds and the N-terminal extracellular tail of CCR4 were studied using capillary zone electrophoresis. The CCR4 chemotaxis inhibition effect was tested in CCR4-transfected HEK293 cells. Several compounds showed potent activities as CCR4 antagonists. Among these compounds, lc is the most active one. Its apparent binding constant of CZE experiment result is （1.569±0.11）× 10s L·mol ^-1, and its percentage inhibition of the HEK293/CCR4 cells migration with the concentration of I gmol·L ^-1 in DMSO is 59%. And compound If has slightly higher affinity to N-terminal of CCR4 according to its apparent binding constant than lb because of the in- troduced ester linkage. Further studies on the mechanism of these compounds are in progress.

关键词： CCR4 antagonists tri-substituted chiral pyrrolidin-2-one derivatives synthesis

Unsupervised hyperspectral unmixing based on robust nonnegative dictionary learning

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2022年第2期33卷 294-304页

作者： LI yang JIANG Bitao LI Xiaobin tian Jing song Xiaorui Department of Space Information Space Engineering UniversityBeijing 101400China Beijing Institute of Remote Sensing Information Beijing 100192China

Considering the sparsity of hyperspectral images(HSIs),dictionary learning frameworks have been widely used in the field of unsupervised spectral ***,it is worth mentioning here that existing dictionary learning method-based unmixing methods are found to be short of robustness in noisy *** improve the performance,this study specifically puts forward a new unsupervised spectral unmixing *** the reason that the solution only functions in a condition that both endmembers and the abundances meet non-negative con-straints,a model is built to solve the unsupervised spectral un-mixing problem on the account of the dictionary learning *** raise the screening accuracy of final members,a new form of the target function is introduced into dictionary learning practice,which is conducive to the growing robustness of noisy HSI ***,by introducing the total variation(TV)terms into the proposed spectral unmixing based on robust nonnega-tive dictionary learning(RNDLSU),the context information under HSI space is to be cited as prior knowledge to compute the abundances when performing sparse unmixing ***-cording to the final results of the experiment,this method makes favorable performance under varying noise conditions,which is especially true under low signal to noise conditions.

关键词： hyperspectral image(HSI) nonnegative dictionary learning norm loss function unsupervised unmixing

维普期刊数据库

Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2018年第2期8卷 306-315页

作者： Zhizhen Qin Shoubao Wang Yihuang Lin ying Zhao Shengqian yang Junke song Tao Xie Jinlong tian song Wu Guanhua Du Beijing Key Laboratory of Drug Target and Screening Research Department of New Drug R&D Institute of Materia Medica Chinese Academy of Medical Science and Peking Union Medical College

A mangiferin aglycon derivative J99745 has been identified as a potent xanthine oxidase(XOD) inhibitor by previous in vitro study. This study aimed to evaluate the hypouricemic effects of J99745 in experimental hyperuricemia mice, and explore the underlying mechanisms. Mice were orally administered 600 mg/kg xanthine once daily for 7 days and intraperitoneally injected 250 mg/kg oxonic acid on the 7 th day to induce hyperuricemia. Meanwhile, J99745(3, 10, and 30 mg/kg), allopurinol(20 mg/kg) or benzbromarone(20 mg/kg) were orally administered to mice for 7 days. On the 7 th day,uric acid and creatinine in serum and urine, blood urea nitrogen(BUN), malondialdehyde(MDA) content and XOD activities in serum and liver were determined. Morphological changes in kidney were observed using hematoxylin and eosin(H&E) staining. Hepatic XOD, renal urate transporter 1(URAT1), glucose transporter type 9(GLUT9), organic anion transporter 1(OAT1) and ATP-binding cassette transporter G2(ABCG2) were detected by Western blot and real time polymerase chain reaction(PCR). The results showed that J99745 at doses of 10 and 30 mg/kg significantly reduced serum urate, and enhanced fractional excretion of uric acid(FEUA). H&E staining confirmed that J99745 provided greater nephroprotective effects than allopurinol and benzbromarone. Moreover, serum and hepatic XOD activities and renal URAT1 expression declined in J99745-treated hyperuricemia mice. In consistence with the ability to inhibit XOD, J99745 lowered serum MDA content in hyperuricemia mice. Our resultssuggest that J99745 exerts urate-lowering effect by inhibiting XOD activity and URAT1 expression, thus representing a promising candidate as an anti-hyperuricemia agent.

关键词： Antihyperuricemic effect Mangiferin aglycon Derivative Xanthine oxidase Urate transporter 1

维普期刊数据库

Reduced graphene oxide-porous In2O3 nanocubes hybrid nanocomposites for room-temperature NH3 sensing

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2020年第8期31卷 2067-2070页

作者： Zhebin tian Peng song Zhongxi yang Qi Wang School of Material Science and Engineering.University of Jinan Ji'nan 250022China

Metal oxide semiconductors(MOS)-reduced graphene oxide(rGO)nanocomposites have attracted great attention for room-tempe rature gas sensing *** development of novel sensing materials is the key issue for the effective detection of ammoniagas at room *** the present work,the novel reduced graphene oxide(rGO)-In2 O3 nanocubes hybrid materials have been prepared via a simple electrostatic self-assembly *** re sults exhibit that the intimate interfacial contact between In2 O3 nanocubes and the rGO sheets are ***,the as-prepared rGO/In2 O3 nanocomposites displayed high sensitivity,fast response and excellent selectivity towards ammonia(NH3)at room-temperature,which clearly uncovers the merit of structural design and rational integration with rGO *** superior gas sensing performance of the rGO/In2 O3 nanocomposites can be attributed to the synergetic effects of rGO sheets and porous In2 O3 *** reported synthesis offers a general approach to rGO/MOS-based semiconductor composites for room-temperature gas sensing applications.

关键词： Reduced graphene oxide In2O3nanocubes Room-temperature Gas sensors Ammonia

维普期刊数据库