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Research on Hepatitis B virus Genotypes and Subgenotypes among Bai Nationality in Dali, Yunnan Province

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Virologica Sinica 2008年第1期23卷 57-62页

作者： Wei LI Yuan-ying shen Xuan-rong ZHANG Lai-feng REN Qiang LI Ru shen Hai-ping ZHAO Department of Microbiology ＆ Immunology Dali University Dali 671000 China Department of Microbiology ＆ Immunology Fenyang College of Shanxi Medical University Fenyang 032200 China

To investigate the distribution of hepatitis B virus (HBV) genotypes and subgenotypes among the Bai nationality in Dali, a total of 100 serum samples from patients with chronic HBV-infection were collected for the detection of HBV genotypes and subgenotypes by genotype-specific primers and restriction fragment length polymorphism (RLFP), respectively. Among the 100 samples, the proportions of genotype B, C and mixed genotype (B+C) were 41%, 25% and 34%, respectively. All the genotype B strains belonged to subgenotype Ba. In genotype C, 84% were Subgenotype Cs and 12% were subgenotype Ce. The distribution of genotypes B, C and B+C showed no significant difference between male and female patients (P=0.182) and among the age groups of patients (P=0.812). The rates of HBeAg/HBeAg positivity were no significantly different among genotypes B, genotype C and mixed genotype (B+C) (P=0.077/P=0.663). In Dali, genotypes B, B+C and C existed among Bai nationality with chronic HBV-infection, and genotype B was the major genotype. Subgenotypes Ba and Cs were the predominant strains in patients with HBV genotype B/C infection. The most prominent characteristic was the higher prevalent rate of mixed genotype (B+C) in patients.

关键词： Hepatitis B virus Genotype Subgenotype Polymerase chain reaction Restriction fragment lengthpolymorphism (RLFP), Bai nationality in China

Optimizing the Duration of Dual Antiplatelet Therapy After Implantation of Drug-eluting Coronary Stents

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Chinese Medical Journal 2015年第6期128卷 711-713页

作者： ying shen Wei-Feng shen Department of Cardiology Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai 200025 China

Percutaneous coronary intervention （PCI） with implantation of drug-eluting stents （DESs） has become the standard of care for coronary artery disease and gives a great impetus to device industry. In 2013, approximately half million patients with coronary artery disease underwent PCI in China with a penetration rate of DES reaching beyond 95%.131 The use of DES including domestic ones is highly effective in preventing coronary restenosis, but there is a collateral cost to be borne in terms of delayed healing or re-endothelialization of the stented arterial segment and risk of stent thrombosisJ41 Therefore.

关键词： Dual Antiplatelet Therapy Percutaneous Coronary Intervention Drug-eluting Coronary Stents

Optimal morphometric and functional assessment of intermediate coronary lesions

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Chinese Medical Journal 2013年第9期126卷 1603-1605页

作者： shen ying shen Wei-feng Department of Cardiology Rui Jin Hospital Jiao Tong University School of Medicine Shanghai 200025China

Coronary lesions of intermediate severity, defined as 50%-70% luminal diameter narrowing by visualestimation at angiography, are frequently encountered in patients with stable or unstable coronary artery disease. Clinical decision making for patients with intermediate coronary stenosis is still challenging, but may be facilitated by assessing the morphology and physiological significance of these lesions.1 It is clear that angiographic stenosis is a highly unreliable surrogate for myocardial ischemia, as a significant proportion of anatomically high-grade lesions do not cause ischemia. Conversely, even for anatomically mild coronary lesions, a non-negligible rate of myocardial ischemia is consistently noted. Because the physiological significance of a lesion is mainly determined by both the severity of a stenosis and the amount of myocardium supplied, coronary angiography alone does not accurately predict the functional significance of intermediate coronary lesions.2,3

关键词： intermediate coronary stenosis intravascular ultrasound,“ fractionalflow reserve,”optical coherence tomography functional significance

Emissions of saturated C6-C10 aldehydes from poplar (Populus simonii×P. pyramidalis ‘Opera 8277’) cuttings at different levels of light intensity

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Journal of Forestry Research 2011年第2期22卷 233-238页

作者： HU Zeng-hui LENG Ping-sheng shen ying-bai WANG Wen-he College of Gardening Beijing University of Agriculture Beijing 102206P. R. China. Key Laboratory for Genetics and Breeding of Forest Trees and Ornamental Plants （Ministry of Education） College of Biological Sciences and Technology Beijing Forestry University Beijing 100083 R R. China. College of Gardening Beijing University of Agriculture Beijing 102206 P. R. China

Aldehydes play an important role in atmospheric chemistry and plant direct and indirect defense against environmental *** this study,the emissions of saturated C6-C10 aldehydes from Populus simonii × *** ＇Opera 8277＇ cuttings were examined by using a gas chromatography/mass spectrometry（GC/MS） technique at three levels of light intensity（400,800 and 1 200 μmol·m-2·s-1）.A positive correlation between the emissions of these aldehydes and light intensity was ***,nordi-hydroguaiaretic acid（NDGA）,a special inhibitor of lipoxygenase（LOX）,significantly inhibited the emissions of C6-C9 aldehydes at three levels of light intensity,but did not influence the emission of decanal（C10）.The emissions of C6-C10 aldehydes in NDGA treated poplar cuttings,exhibited the same positive correlation with light *** results indicated that LOX pathway contributes to the emissions of C6-C9 aldehydes,whereas some pathways regulated by light intensity might be a universal mechanism for emissions of C6-C10 aldehydes.

关键词： C6-C10 aldehydes light intensity lipoxygenase NDGA Populus simonii × P.pyramidalis 'Opera 8277'

Extracorporeal membrane oxygenation treatment for high-risk pulmonary embolism with cardiac arrest in a young adult male

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World Journal of Emergency Medicine 2021年第4期12卷 324-326页

作者： Zhi-rong Zhang Xia-qing Zhou Zhao-kun Fan Yin Shi ying-ying shen Chen Zhu Wen Feng Ling-cong Wang Department of Intensive Care Unit the First Affi liated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310006China Zhejiang Chinese Medical University Hangzhou 310053China Department of Intensive Care Unit the First Affi liated Rehabilitation Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou 310023China

Dear editor,A 21-year-old male student was admitted to the emergency department of our hospital due to chest distress,dyspnea for 1.5 hours, and loss of consciousness for one minute. Before admission, the patient had been advised rest for two months because of left ankle sprain, leading to less activity. At admission, the patient was unconscious,with facial cyanosis, and his limbs were cold.

关键词： admitted distress cardiac

Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第8期14卷 705-712页

作者： Zhen SUN ying shen Lin LU Rui-yan ZHANG Li-jin PU Qi ZHANG Zheng-kun YANG Jian HU Qiu-jing CHEN Wei-feng shen Department of Cardiology Shanghai Ruijin Hospital Institute of Cardiovascular Diseases Shanghai Jiao Tong University School of Medicine

Objective： Coronary collateral circulation is an alternative source of blood supply to myocardium in the presence of advanced coronary artery disease. We sought to determine which clinical and angiographic variables are associated with collateral development in patients with stable angina and chronic total coronary occlusion. Methods： Demographic variables, biochemical measurements, and angiographic findings were collected from 478 patients with stable angina and chronic total coronary occlusion. The presence and extent of collaterals supplying the distal aspect of a total coronary occlusion from the contra-lateral vessel were graded from 0 to 3 according to the Rentrop scoring system. Results： Low （Rentrop score of 0 or 1） and high （Rentrop score of 2 or 3） coronary collateralizations were detected in 186 and 292 patients, respectively. Despite similar age, cigarette smoking, and medical treatment, patients with low collateralization were female in a higher proportion and less hypertensive, and had higher rates of type 2 diabetes and dyslipidemia than those with high coUateralization （for all comparisons, P〈0.05）. In addition, patients with low collateralization exhibited more single-vessel disease, less right coronary artery occlusion, more impaired renal function, and higher serum levels of high-sensitivity C-reactive protein （hsCRP） compared with those with high col- lateralization. Multivariate analysis revealed that age of 〉65 years, female gender, diabetes, no history of hypertension dyslipidemia, moderate to severe renal dysfunction, single-vessel disease, and elevated hsCRP levels were inde- pendently associated with low coronary collateralization. Conclusions： Coronary collateralization was reduced in almost 40% of stable angina patients with chronic total occlusion, which was related to clinical and angiographic factors. The impact of coronary collateralization on outcomes after revascularization needs further investigation.

关键词： Stable angina Coronary collateral circulation Risk factors Angiography Chronic total coronary occlusion

A Survey of the Development of Library Automation and Networking in China

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图书情报工作 1996年第3期 28-31+61页

作者： shen ying Zhang Jianyong(The Documentation and Information Centre of the Chinese Academy of Sciences)

Surveys the current status and progress of library automation and networking in China by presenting some important information management systems and information networks, and describes the prospects of library automa... 详细信息

关键词： library automation networking information management

Genetic Relationship between Francisella Tularensis Strains from China and from Other Countries

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Biomedical and Environmental Sciences 2011年第3期24卷 310-314页

作者： WANG YanHua HAI Rong ZHANG ZhiKai XIA LianXu CAI Hong LIANG ying shen XiaoNa YU DongZheng State Key Laboratory for Infectious Disease Prevention and Control National Institute for Communicable DiseaseControl and Prevention Chinese Center for Disease Control and Prevention Beijing 102206 China

Objective To study the types of subspecies of Francisella tularensis from China and to investigate the genetic relationships between F. tularensis strains from China and from other countries. Methods Ten strains of F. tulorensis isolated from China were amplified by using typing primers Cl/C4 and RD1. On the basis of the lengths of the polymerase chain reaction （PCR） products, it was concluded that these strains of F. tularensis belonged to the same subspecies. At the same time, thefopA, tul4, and 16S rRNA genes of the I0 strains were amplified, and a three-gene based phylogenetic analysis was performed using the Molecular Evolutionary Genetics Analysis software version 4.0. Results The 10 strains of F. tularensis from China were all identified as belonging to subspecies holarctica （type B）. We found no direct relationship between the genotypes of F. tulurensis subsp. holarctica and the geographical area from where they were isolated. Conclusion The F. tularensis strains isolated from North China mainly belong to subspecies holorctica （type B）. The strains of F. tularensis subsp, holarctico from China may have evolved earlier than those from Europe and North America.

关键词： Francisella tularensis Tularemia Phylogenetic analysis Genotyping, PCR

Economic Burden of Hand,Foot,and Mouth Disease-Beijing Municipality,China,2016–2019

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China CDC weekly 2023年第43期5卷 953-957页

作者： ying shen Siqi Li Da Huo Shuaibing Dong Yang Yang Lei Jia Quanyi Wang Xiaoli Wang Beijing Center for Disease Prevention and Control BeijingChina Beijing Research Center for Respiratory Infectious Diseases BeijingChina School of Public Health Capital Medical UniversityBeijingChina

Summary What is already known about this topic?Current research regarding hand,foot,and mouth disease(HFMD)has primarily concentrated on the economic impacts,drawing from retrospective or sentinel hospital-based *** a... 详细信息

关键词： primarily cases concentrated