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Nano-Micro Letters 2025年第1期17卷 46-97页

作者： Xueyan Zhang Shichao Cheng Chuankai Fu Geping yin Liguang wang Yongmin Wu Hua Huo State Key Laboratory of Space Power‑Sources School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310058People’s Republic of China State Key Laboratory of Space Power-Sources 2965 Dongchuan RoadMinhang DistrictShanghai 200240People’s Republic of China

To address the limitations of contemporary lithium-ion batteries,particularly their low energy density and safety concerns,all-solid-state lithium batteries equipped with solid-state electrolytes have been identified as an up-and-coming *** the various SEs,organic–inorganic composite solid electrolytes(OICSEs)that combine the advantages of both polymer and inorganic materials demonstrate promising potential for large-scale ***,OICSEs still face many challenges in practical applications,such as low ionic conductivity and poor interfacial stability,which severely limit their *** review provides a comprehensive overview of recent research advancements in ***,the influence of inorganic fillers on the main functional parameters of OICSEs,including ionic conductivity,Li+transfer number,mechanical strength,electrochemical stability,electronic conductivity,and thermal stability are systematically *** lithium-ion conduction mechanism of OICSE is thoroughly analyzed and concluded from the microscopic ***,the classic inorganic filler types,including both inert and active fillers,are categorized with special emphasis on the relationship between inorganic filler structure design and the electrochemical performance of ***,the advanced characterization techniques relevant to OICSEs are summarized,and the challenges and perspectives on the future development of OICSEs are also highlighted for constructing superior ASSLBs.

关键词： Composite solid electrolytes Inorganic filler Interfacial stability Li-ion conduction mechanism Characterization techniques

2000-2014年蒙古高原植被覆盖时空变化特征及其对地表水热因子的响应

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冰川冻土 2017年第6期39卷 1345-1356页

作者：温都日娜包玉海银山王永芳内蒙古师范大学地理科学学院内蒙古呼和浩特010022 东北师范大学环境学院吉林长春130024

利用MODIS NDVI数据、同期地表水热组合数据和植被类型数据,对2000-2014年蒙古高原生长季和三季(春、夏、秋季)植被覆盖时空演变特征及其对地表水热因子响应模式进行分析。研究表明:这15 a来,蒙古高原生长季及三季归一化植被指数NDVI均... 详细信息

利用MODIS NDVI数据、同期地表水热组合数据和植被类型数据,对2000-2014年蒙古高原生长季和三季(春、夏、秋季)植被覆盖时空演变特征及其对地表水热因子响应模式进行分析。研究表明:这15 a来,蒙古高原生长季及三季归一化植被指数NDVI均呈增加趋势,且呈显著增加趋势区域主要集中在内蒙古地区,一定程度上反映了该地区生态恢复工程的有效性。研究区植被覆盖变化与地表水分指数LSWI有密切的关系,因此证明研究区植被覆盖的增加归因于自然和人为因素的共同作用。不同类型植被NDVI均呈增加趋势,其中荒漠植被NDVI增加最明显,森林植被增加平缓,且存在季节性差异。此外,不同类型植被NDVI受水热因子影响也存在季节性差异。

关键词：蒙古高原归一化植被指数(NDVI) 地表温度(LST) 地表水分指数(LSWI)

Correlation between anxiety, depression, and social stress in young patients with thoracolumbar spine fractures

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World Journal of Psychiatry 2025年第1期15卷 83-92页

作者： Bo wang Da Shi yin-Di Sun Bo Dong Joint Ward of Orthopedics Department of TCM Honghui HospitalXi'an Jiaotong UniversityXi’an 710054Shaanxi ProvinceChina Pain Ward of Orthopedics Department of TCM Honghui HospitalXi'an Jiaotong UniversityXi’an 710054Shaanxi ProvinceChina

BACKGROUND Traumatic injuries,such as falling,car accidents,and crushing mostly cause spinal fractures in young and middle-aged people,and>50%of them are thoracolumbar *** kind of fracture is easily combined with serious injuries to peripheral nerves and soft tissues,which causes paralysis of the lower limbs if there is no timely rehabilitation *** patients with thoracolumbar fractures find it difficult to recover after the operation,and they are prone to depression,low self-esteem,and other negative *** To investigate the association between anxiety,depression,and social stress in young patients with thoracolumbar spine fractures and the effect on rehabilitation *** This study retrospectively analyzed 100 patients admitted to the orthopedic department of Honghui Hospital,Xi’an Jiaotong University who underwent thoracolumbar spine fracture surgery from January 2022 to June *** general data of the patients were assessed with the Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD),life events scale,and social support rating scale(SSRS)to identify the correlation between anxiety,depression scores,and social stress and social *** Japanese Orthopedic Association(JOA)was utilized to evaluate the rehabilitation outcomes of the patients and to analyze the effects of anxiety and depression scores on *** According to the scores of HAMD and HAMA in all patients,the prevalence of depression in patients was 39%(39/100),and the prevalence of anxiety was 49%(49/100).Patients were categorized into non-depression(n=61)and depression(n=39),non-anxiety(n=51),and anxiety(n=49)*** significant differences in gender,occupation,Pittsburgh Sleep Quality Index(PSQI)score,and monthly family income were observed between the non-depression and depression groups(P<0.05).A significant difference in occupation and PSQI score was found between the non-anxiety and anxiety *** depression(r=0

关键词： Patients with thoracolumbar fractures Anxiety Depression Social pressure Social support

龟鹿二仙胶对地塞米松诱导骨髓间充质干细胞损伤的保护作用

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南京中医药大学学报 2017年第4期33卷 395-398页

作者：徐卫峰费逸明王建伟尹恒王善付葛卫红南京医科大学药学院江苏南京211166 南京中医药大学无锡附属医院江苏无锡214071 南京大学医学院附属鼓楼医院江苏南京210008

目的研究龟鹿二仙胶对地塞米松诱导骨髓间充质干细胞损伤的保护作用。方法体外培养SD大鼠骨髓间充质干细胞,传至第二代后分5组培养:正常组、地塞米松(10-8 mol/L)组、骨化三醇含药血清组、龟鹿二仙胶含药血清低剂量组、龟鹿二仙胶含药... 详细信息

目的研究龟鹿二仙胶对地塞米松诱导骨髓间充质干细胞损伤的保护作用。方法体外培养SD大鼠骨髓间充质干细胞,传至第二代后分5组培养:正常组、地塞米松(10-8 mol/L)组、骨化三醇含药血清组、龟鹿二仙胶含药血清低剂量组、龟鹿二仙胶含药血清高剂量组。MTT法检测骨髓间充质干细胞活力,检测细胞上清中的超氧化物歧化酶(SOD)、丙二醛(MDA)、炎症因子白介素-6(IL-6)、小鼠白介素1β(IL-1β)、肿瘤坏死因子-α(TNF-α)。采用Western blot检测Nrf-2/HO-1/NF-κB信号通路蛋白表达。结果龟鹿二仙胶能显著提高细胞活力,增加SOD水平、降低MDA水平、降低炎症因子水平,增加蛋白Nrf-2、HO-1蛋白表达水平,降低NF-κB信号蛋白表达。结论龟鹿二仙胶对地塞米松诱导骨髓间充质干细胞损伤有保护作用,且作用与调控Nrf-2/HO-1/NF-κB信号相关。

关键词：龟鹿二仙胶地塞米松骨髓间充质干细胞氧化应激炎症

Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss

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Neural Regeneration Research 2025年第10期20卷 3025-3039页

作者： Jia Fang Zhuangzhuang Li Pengjun wang Xiaoxu Zhang Song Mao yini Li Dongzhen Yu Xiaoyan Li Yazhi Xing Haibo Shi shankai yin Department of Otolaryngology Head and Neck Surgery Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineOtolaryngology Institute of Shanghai Jiao Tong UniversityShanghai Key Laboratory of Sleep Disordered BreathingShanghaiChina Department of Otorhinolaryngology-Head and Neck Surgery Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Aminoglycosides are a widely used class of antibacterials renowned for their effectiveness and broad antimicrobial ***,their use leads to irreversible hearing damage by causing apoptosis of hair cells as their direct *** addition,the hearing damage caused by aminoglycosides involves damage of spiral ganglion neurons upon *** investigate the mechanisms underlying spiral ganglion neuron degeneration induced by aminoglycosides,we used a C57BL/6J mouse model treated with *** found that the mice exhibited auditory deficits following the acute loss of outer hair *** ganglion neurons displayed hallmarks of pyroptosis and exhibited progressive degeneration over *** profiling of these neurons showed significant upregulation of genes associated with inflammation and immune response,particularly those related to the NLRP3 *** of the canonical pyroptotic pathway in spiral ganglion neurons was observed,accompanied by infiltration of macrophages and the release of proinflammatory *** intervention targeting NLRP3 using Mcc950 and genetic intervention using NLRP3 knockout ameliorated spiral ganglion neuron degeneration in the injury *** findings suggest that NLRP3 inflammasome-mediated pyroptosis plays a role in aminoglycoside-induced spiral ganglion neuron *** of this pathway may offer a potential therapeutic strategy for treating sensorineural hearing loss by reducing spiral ganglion neuron degeneration.

关键词： degeneration hearing loss macrophages Mcc950 neuroinflammation NLRP3 inflammasome ototoxicity pyroptosis sensorineural hearing loss spiral ganglion neuron

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小麦长管蚜消长动态及经济阈值

华北农学报 1989年第S1期4卷 140-144页

作者：赵文臣尹善王进忠屈振刚郭金霞河北省农林科学院植物保护研究所

作者于1980—1988年在河北保定对小麦田蚜虫的优势种——小麦长管蚜(Ma-crosiphum avenae Fabr.)种群消长动态及百茎蚜量与小麦千粒重降低率的关系进行了研究.结果表明:(1) 随季节变化长管蚜的消长呈双峰型.夏季蚜峰正值小麦灌浆时期,... 详细信息

作者于1980—1988年在河北保定对小麦田蚜虫的优势种——小麦长管蚜(Ma-crosiphum avenae Fabr.)种群消长动态及百茎蚜量与小麦千粒重降低率的关系进行了研究.结果表明:(1) 随季节变化长管蚜的消长呈双峰型.夏季蚜峰正值小麦灌浆时期,这是防治的关键期;(2)灌浆初期、中期的蚜量与千粒重损失率均呈极显著相关.相关系数分别为0.9648和0.9554.回归式分别为:y_1=0.010383x_1-0.871208±3.07与y_2=0.008019x_2+0.182175±1.69;(3)根据河北省当前小麦产量水平,商品价格及防治现状和费用计算,小麦长管蚜的经济阈值,在灌浆初斯为600头,中期为650头.

关键词：小麦长管蚜种群消长动态经济阈值

Molecule‑Level Multiscale Design of Nonflammable Gel Polymer Electrolyte to Build Stable SEI/CEI for Lithium Metal Battery

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Nano-Micro Letters 2025年第1期17卷 404-423页

作者： Qiqi Sun Zelong Gong Tao Zhang Jiafeng Li Xianli Zhu Ruixiao Zhu Lingxu wang Leyuan Ma Xuehui Li Miaofa Yuan Zhiwei Zhang Luyuan Zhang Zhao Qian Longwei yin Rajeev Ahuja Chengxiang wang Key Laboratory for Liquid‑Solid Structural Evolution and Processing of Materials(Ministry of Education) School of Materials Science and EngineeringShandong UniversityJinan 250061People’s Republic of China Condensed Matter Theory Department of Physics and AstronomyUppsala UniversityUppsala 75120Sweden

The risk of flammability is an unavoidable issue for gel polymer electrolytes(GPEs).Usually,flameretardant solvents are necessary to be used,but most of them would react with anode/cathode easily and cause serious interfacial instability,which is a big challenge for design and application of nonflammable ***,a nonflammable GPE(SGPE)is developed by in situ polymerizing trifluoroethyl methacrylate(TFMA)monomers with flame-retardant triethyl phosphate(TEP)solvents and LiTFSI–LiDFOB dual lithium *** is strongly anchored to PTFMA matrix via polarity interaction between-P=O and-CH_(2)CF_(3).It reduces free TEP molecules,which obviously mitigates interfacial reactions,and enhances flame-retardant performance of TEP *** TEP molecules are also inhibited in solvation of Li^(+),leading to anion-dominated solvation sheath,which creates inorganic-rich solid electrolyte interface/cathode electrolyte interface *** coordination structure changes Li^(+)transport from sluggish vehicular to fast structural transport,raising ionic conductivity to 1.03 mS cm^(-1) and transfer number to 0.41 at 30℃.The Li|SGPE|Li cell presents highly reversible Li stripping/plating performance for over 1000 h at 0.1 mA cm^(−2),and 4.2 V LiCoO_(2)|SGPE|Li battery delivers high average specific capacity>120 mAh g^(−1) over 200 *** study paves a new way to make nonflammable GPE that is compatible with Li metal anode.

关键词： Anchoring effect Nonflammable gel electrolyte In situ cross-linked Electrode-electrolyte interface Li metal battery

Human-induced pluripotent stem cell-derived neural stem cell exosomes improve blood-brain barrier function after intracerebral hemorrhage by activating astrocytes via PI3K/AKT/MCP-1 axis

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Neural Regeneration Research 2025年第2期20卷 518-532页

作者： Conglin wang Fangyuan Cheng Zhaoli Han Bo Yan Pan Liao Zhenyu yin Xintong Ge Dai Li Rongrong Zhong Qiang Liu Fanglian Chen Ping Lei Department of Geriatrics Tianjin Medical University General HospitalTianjinChina School of Medicine Nankai UniversityTianjinChina Tianjin Neurological Institute TianjinChina

Cerebral edema caused by blood-brain barrier injury after intracerebral hemorrhage is an important factor leading to poor ***-induced pluripotent stem cell-derived neural stem cell exosomes(hiPSC-NSC-Exos)have shown potential for brain injury repair in central nervous system *** this study,we explored the impact of hiPSC-NSC-Exos on blood-brain barrier preservation and the underlying *** results indicated that intranasal delivery of hiPSC-NSC-Exos mitigated neurological deficits,enhanced blood-brain barrier integrity,and reduced leukocyte infiltration in a mouse model of intracerebral ***,hiPSC-NSC-Exos decreased immune cell infiltration,activated astrocytes,and decreased the secretion of inflammatory cytokines like monocyte chemoattractant protein-1,macrophage inflammatory protein-1α,and tumor necrosis factor-αpost-intracerebral hemorrhage,thereby improving the inflammatory *** sequencing indicated that hiPSC-NSC-Exo activated the PI3K/AKT signaling pathway in astrocytes and decreased monocyte chemoattractant protein-1 secretion,thereby improving blood-brain barrier *** with the PI3K/AKT inhibitor LY294002 or the monocyte chemoattractant protein-1 neutralizing agent C1142 abolished these *** summary,our findings suggest that hiPSC-NSC-Exos maintains blood-brain barrier integrity,in part by downregulating monocyte chemoattractant protein-1 secretion through activation of the PI3K/AKT signaling pathway in astrocytes.

关键词： AKT astrocyte blood-brain barrier cerebral edema exosomes human-induced pluripotent stem cells intracerebral hemorrhage neural stem cells neuroinflammation PI3K

基于MODIS17A3的呼伦贝尔沙地植被NPP时空格局变化分析

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曲阜师范大学学报（自然科学版） 2017年第4期43卷 110-113页

作者：郭连发银山王艳琦彭秀清内蒙古师范大学地理科学学院内蒙古师范大学内蒙古自治区遥感与地理信息重点实验室内蒙古自治区呼和浩特市010022

植被净初级生产力(NPP)可以直接反映植物的生产能力.为研究呼伦贝尔沙地植被NPP时空变化情况,本文选用NPP产品数据MODIS17A3进行处理后,结合气温降水以及经济产业数据,利用简单差值法、一元线性回归分析的方法对该地区沙地植被NPP的时... 详细信息

植被净初级生产力(NPP)可以直接反映植物的生产能力.为研究呼伦贝尔沙地植被NPP时空变化情况,本文选用NPP产品数据MODIS17A3进行处理后,结合气温降水以及经济产业数据,利用简单差值法、一元线性回归分析的方法对该地区沙地植被NPP的时空变化以及驱动力进行了分析.经过研究发现:(1)呼伦贝尔沙地地区植被NPP呈现由东向西递减的趋势;(2)植被NPP增长最大的是鄂温克族自治旗与新巴尔虎右旗,而满洲里与海拉尔地区呈现负增长比重较大,分别占到12.2%、6.33%;(3)15年以来该地区总体NPP呈现增长模式,生态恢复比较好.

关键词：沙地 NPP 时空格局