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Effect of moxibustion on long-term memory in vascular dementia model rats

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World Journal of Acupuncture-Moxibustion 2019年第1期29卷 63-68页

作者： Yue LI Jun YANG Li GUI yin-qiu fan Graduate School of Anhui University of Traditional Chinese Medicine Hefei 230000Anhui ProvinceChina First Affiliated Hospital of Anhui University of Traditional Chinese Medicine Hefei 230000Anhui ProvinceChina

Objective: To observe the effects on spatial long-term memory in the rats with vascular dementia(VD)treated with moxibustion for resolving stasis and promoting meridian ***: The modified 2-vascular occlusion(2-VO) method was used to prepare VD animal model. The rats were randomized into a sham-operation group, a model group, a moxibustion group and a western medication group, 15 rats in each one. In the moxibustion group, mild warm moxibustion was applied to"Bǎihuì(百会 GV 20)" "DàZhuī(大椎 GV 14)" and "Shéntíng(神庭 GV 24)". 20 min at each point, once a day, for 3 weeks consecutively. In the western medicaion group, mouse nerve growth factor(NGF) was injected intraperitoneally, 0.18 mL/kg, once a day, for 3 weeks consecutively. Morris water maze test was used, the time of the first passing platform, the frequency of passing-platform and swimming speed in120 s were determined of the rats in each group. Western blot were used to test the protein expressions of hippocampal Nestin and ***: At the end of three courses of treatment, compared with sham-operation group, the difference was not significant statistically in swimming speed in the model group, the moxibustion group and the western medication group separately(all P>0.05). Three days after modeling, the mean of escape latency was prolonged obviously in the modeled rats compared with the rats in the shamoperation group(88.84 ± 19.94 vs 18.15 ±9.41, P< 0.01). At the end of three courses of treatment, compared with the sham-operation group(22.01 ± 10.07), the mean of escape latency was different statistically in the model group(89.18± 19.70), the moxibustion group(37.21 ±13.31) and the western medication group separately(51.50± 16.15), all P<0.01. Compared with the model group, the mean of escape latency was shortened in the moxibustion group and western medication group respectively(37.21 ± 13.31 vs89.18 ± 19.70, 51.50 ± 16.15 vs 89.18 ± 19.70, both P< 0.01). Compared with the western medication g

关键词： Vascular dementia Water maze test Moxibustion Long term memory

Research on Credit Regulation Mechanism of E-commerce Platform Based on Evolutionary Game Theory

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Journal of Systems Science and Systems Engineering 2024年第3期33卷 330-359页

作者： Zeguo qiu Yuchen yin Yao Yuan Yunhao Chen School of Computer and Information Engineering Harbin University of CommerceHarbin150028China School of Management Harbin University of CommerceHarbin150028China

In the growing e-commerce industry,the problem of malicious business operations has become increasingly prominent,exposing many problems such as weak supervision of e-commerce platforms and no way for consumers to *** order to solve the problems of counterfeit and shoddy products on e-commerce platforms and promote the sustainable development of the e-commerce industry in China,this paper constructs a three-party evolutionary game model of e-commerce platforms,merchants,and consumers,investigates the influence of each influencing factor on each party’s strategy choice,and provides targeted suggestions to e-commerce platforms based on relevant ***,the impact of several important parameters on the equilibrium solution is discussed through sensitivity *** results show that:1)the smaller the cost difference between active and negative regulation,the more the e-commerce platform tends to active regulation strategy,but increasing fines for dishonest merchants and consumer complaints have little impact on the e-commerce platform;2)increasing consumer compensation,creating an honest business environment,and reducing the cost of honest business all help companies tend to operate in good faith;3)the only factor that affects the tendency of consumer complaint strategies is the cost of *** loss suffered by silence and the compensation given to consumers have little effect on consumers’tendency to complain *** results can provide theoretical guidance for participants to make useful strategic decisions in the e-commerce market.

关键词： Evolutionary game e-commerce data simulation

Separation of La(Ⅲ),Ce(Ⅳ)and Ca(Ⅱ)from bastnaesite using acidic phosphonic chitosan and rotating disk membrane

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Journal of Rare Earths 2024年第5期42卷 995-1000,I0007页

作者： Dandan Lu Wenhui Li Linlin fan Yunren qiu School of Chemistry and Chemical Engineering Central South UniversityChangsha410083China

The separation of rare earths is difficult due to their similar properties and the complex characteristics of associated vein o ***-ultrafiltration(CUF)and shear induced o rderly dissociation coupling with ultrafiltration(SIODUF)were used to separate metal ions(M,M=La(Ⅲ),Ce(Ⅳ)and Ca(Ⅱ))from simulated bastnaesite leaching solution using acidic phosphonic chitosan(aPCS)and rotating disk *** of simultaneous removal of metallic ions was investigated by CUF,and suitable conditions were obtained for C/M 10.0(mass ratio of complexant to metal ions)and pH *** shear stabilities of aPCS-M complexes were explored at different pH values and the results show that the complexes can dissociate at a certain rotational speed,the critical *** critical s hear rates of aPCS-La,aPCS-Ce and aPCS-Ca complexes at pH 5.0 were calculated as 1.42×10^(5).1.69×10^(5) and 9.75×10^(4) s^(-1),*** order of complexes shear stability is aPCS-Ca aPCS-La<*** high selective separation of M and regeneration of aPCS were achieved by SIODUF in the light of the difference of aPCSM complexes shear *** separation coefficientsβLa/Ce andβCa/La reach 31.2 and 53.9,respectively.

关键词： Bastnaesite Rare earths Complexation-ultrafiltration Acidic phosphonic chitosan Rotating disk membrane

Phase-field lattice-Boltzmann study on fully coupled thermal-solute-convection dendrite growth of Al-Cu alloy

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China Foundry 2024年第2期21卷 125-136页

作者： yin-qi qiu Meng-wu Wu Xun-peng Qin Shou-mei Xiong Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Longzhong Laboratory Xiangyang 441000HubeiChina School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China

Dendrite growth is a complex liquid-solid phase transition process involving multiple physical factors.A phase-field lattice-Boltzmann method was developed to simulate the two-and three-dimension dendrite growth of Al-Cu *** effect of fully coupled thermal-solute-convection interaction on the dendrite growth was investigated by incorporating a parallel-adaptive mesh refinement algorithm into the numerical *** accurately reproducing the latent heat release,solute diffusion and convective transport behaviors at the liquidsolid interface,the interaction mechanism among thermal-solute-convection transport as well as their coupling effects on the dendrite growth dynamics were *** simulation results show that the release of latent heat slows down the dendrite growth rate,and both natural and forced convection disrupt the symmetrical growth of *** combination makes the growth of dendrites more complex,capturing important physical aspects such as recalescence,dendrite tip splitting,dendrite tilting,dendrite remelting,and solute plume in the simulation *** on the robustness and powerful ability of the numerical model,the formation mechanisms of these physical aspects were revealed.

关键词： simulation phase field dendrite growth thermal-solute-convection interaction

Alleviated photoinhibition on nitrification in the Indian Sector of the Southern Ocean

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Acta Oceanologica Sinica 2024年第7期43卷 52-69页

作者： Lingfang fan Min Chen Zifei Yang Minfang Zheng Yusheng qiu College of Ocean and Earth Sciences Xiamen UniversityXiamen 361102China

Nitrification,a central process in the marine nitrogen cycle,produces regenerated nitrate in the euphotic zone and emits N_(2)O,a potent greenhouse gas as a *** regulatory mechanisms of nitrification in the Southern Ocean,which is a critical region for CO_(2)sequestration and radiative benefits,remain poorly ***,we investigated the in situ and dark nitrification rates in the upper 500 m and conducted substrate kinetics experiments across the Indian Sector in the Cosmonaut and Cooperation seas in the late austral *** findings indicate that light inhibition of nitrification decreases exponentially with depth,exhibiting a light threshold of 0.53%photosynthetically active radiation.A positive relationship between dark nitrification and apparent oxygen utilization suggests a dependence on substrate availability from primary ***,an increased NH_(4)^(+) supply can act as a buffer against photo-inhibitory ***,substrate affinity(α)increases with depth and transitions from light to dark,decreases with increasing ambient NH_(4)^(+)and exhibits a latitudinal distribution,reflecting substrate utilization *** also reveal that upwelling in Circumpolar Deep Water(CDW)stimulates nitrification through the introduction of potentially higher iron and deep diverse nitrifying microorganisms with higherα.We conclude that although light is the primary limiting factor for nitrification in summer,coupling between substrate availability and CDW upwelling can overcome this limitation,thereby alleviating photoinhibition by up to 45%±5.3%.

关键词： nitrification light inhibition substrate affinity circumpolar deep water(CDW)upwelling the Southern Ocean

Platelet-based bioactive systems guided precision targeting and immune regulation for cancer therapy

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Nano Research 2024年第9期17卷 8269-8284页

作者： Xinyi Cai Long qiu Zhenying Diao Lintao Cai Ting yin Hong Pan Guangdong Key Laboratory of Nanomedicine CAS-HK Joint Lab of BiomaterialsCAS Key Laboratory of Biomedical Imaging Science and SystemInstitute of Biomedicine and BiotechnologyShenzhen Institute of Advanced Technology(SIAT)Chinese Academy of SciencesShenzhen 518055China School of pharmacy Guangdong Medical UniversityDongguan 523808China Sino-Euro Center of Biomedicine and Health Shenzhen 518024China

The antitumor effects of conventional drug carriers are often attenuated and limited in application by biological barriers associated with tumor heterogeneity and resistance brought about by low tumor *** the rapid development of nanotechnology,naturally derived bioactive materials,and live cell carriers,a promising strategy emerges for targeting the tumor microenvironment(TME)for precision cancer *** unique injury-targeting properties of platelets can significantly extend functional activity,which cannot be achieved with conventional *** this review,three strategies based on platelet-engineered materials are systematically described,namely nanoparticles for platelet membrane camouflage,engineered activated platelets,and targeted-platelets ***-based nanomaterials can effectively coordinate local and distant tumor-host crosstalk with controlled active tumor site recognition and killing effects due to the presence of specific membrane proteins on the surface and the self-secretion of a large number of *** advances in platelets for effectively overcoming biological barriers and reducing immune resistance in cancer immunotherapy applications will be discussed in future clinical *** review provides an overview of recent research advances in platelet-based bioactive material-directed immunotherapy and chemotherapy to inform future antitumor combination therapies.

关键词： platelets bionic targeting immune modulation precision therapy deep penetration

Enhanced activation of peroxymonosulfate on layered molybdenum disulfide loaded with Co-La bimetallic oxide for efficient degradation of chloramphenicol

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Rare Metals 2024年第9期43卷 4628-4635页

作者： Yu-Ning fan Yun-qiu Zhang San-Shuang Gao Zeng-Hui Bi yin Wang Shu-Xing Zhou Qian Liu Tian-Ping Lv Guang-Zhi Hu Institute for Ecological Research and Pollution Control of Plateau Lakes School of Ecology and Environmental ScienceYunnan UniversityKunming 650504China Hubei Key Laboratory of Low Dimensional Optoelectronic Materials and Devices Hubei University of Arts and ScienceXiangyang 441053China Institute for Advanced Study Chengdu UniversityChengdu 610106China

The use of transition metal-activated peroxymonosulfate(PMS)as an advanced oxidation technology has gained *** study developed a catalyst using cobaltDlanthanum bimetallic oxide supported on layered molybdenum disulfide(Mo S_(2))as a *** CoDLa/Mo S_(2)catalyst was synthesised through coprecipitation,followed by calcination with an optimised metal ratio of Co:La=2:1 to activate PMS and degrade trace chloramphenicol(CAP)in *** chemical composition of the catalyst was confirmed using X-ray diffraction(XRD)and X-ray photoelectron spectroscopy(XPS).At catalyst and PMS dosages of 0.1 and 0.5 g·L^(-1),respectively,the degradation rate of CAP was 95%with in 30 *** catalyst exhibitedstrong resistance to most interfering anions and maintained a high degradation rate at p H *** chromatographyDmass spectrometry analysis revealed the potential degradation pathways of CAP in the CoDLa/Mo S_(2)(2:1)/PMS *** other pollutants,such as oxytetracycline,complete degradation was achieved within 20 min,demonstrating the broad applicability of the CoDLa/Mo S_(2)(2:1)/PMS system for the degradation and removal of antibiotic organic contaminants.

关键词： catalyst molybdenum disulfide

MnO-pillared graphene blocks enabling the ultrastable and ultrafast aqueous zinc ion batteries

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Science China Chemistry 2024年第9期67卷 2930-2940页

作者： Zheng Liu Zhipeng qiu Zhiyuan Li Tong Wei Zhuangjun fan Huan Pang School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China School of Materials Science and Engineering China University of PetroleumQingdao 266580China

Due to the low cost,high theoretical capacity,and environmental friendliness,manganese-based cathodes are regarded as promising alternatives for aqueous zinc ion batteries(AZIBs).However,the practicality of the zinc-manganese system is faced with great challenges,such as the inevitable structural collapse of the cathode and controversial energy storage ***,we propose a novel concept of spatial deposition mechanism through the addition of MnSO_(4) additives in the Mn O-pillared graphene blocks(G-MnO).The covalent interface between MnO nanoparticles and multilayered graphene nanosheets can construct an in-built micro-electric field,which is beneficial for consecutive electron transfer(in both horizontal and vertical directions).On this basis,the surficial activity of MnO confined in the interlayered nano-space is greatly enhanced and provides enough spatial deposition and subsequent reaction site for MnSO_(4) additives,thus firstly extending the surficial controlled process to stereoscopic space,effectively improving the electrochemical performance of ***,the assembled Zn//G-Mn O battery exhibits an excellent rate capability of 281.5 mAhg^(-1)at 0.1 A g^(-1)and 106 mAhg^(-1)at 20 Ag^(-1),and impressive cycling stability(93 mAhg^(-1)remaining after 5,000 cycles).This finding may provide a new opportunity for the rational design of surficial controlled energy storage and conversion devices.

关键词： zinc-ion battery manganese monoxide laminated constructure ultrahigh rate performance graphene

Grain yield and N uptake of maize in response to increased plant density under reduced water and nitrogen supply conditions

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Journal of Integrative Agriculture 2024年第1期23卷 122-140页

作者： Jingui Wei Qiang Chai Wen yin Hong fan Yao Guo Falong Hu Zhilong fan QimingWang State Key Laboratory of Aridland Crop Science Lanzhou 730070China College of Agronomy Gansu Agricultural UniversityLanzhou 730070China College of Life Sciences Northwest Normal UniversityLanzhou 730070China

The development of modern agriculture requires the reduction of water and chemical N fertilizer *** the planting density can maintain higher yields,but also consumes more of these restrictive ***,whether an increased maize density can compensate for the negative effects of reduced water and N supply on grain yield and N uptake in the arid irrigated areas remains *** study is part of a long-term positioning trial that started in 2016.A split-split plot field experiment of maize was implemented in the arid irrigated area of northwestern China in 2020 to *** treatments included two irrigation levels:local conventional irrigation reduced by 20%(W1,3,240 m^(3)ha^(-1))and local conventional irrigation(W2,4,050 m^(3)ha^(-1));two N application rates:local conventional N reduced by 25%(N1,270 kg ha^(-1))and local conventional N(360 kg ha^(-1));and three planting densities:local conventional density(D1,75,000 plants ha^(-1)),density increased by 30%(D2,97,500 plants ha-1),and density increased by 60%(D3,120,000 plants ha^(-1)).Our results showed that the grain yield and aboveground N accumulation of maize were lower under the reduced water and N inputs,but increasing the maize density by 30% can compensate for the reductions of grain yield and aboveground N accumulation caused by the reduced water and N *** water was reduced while the N application rate remained unchanged,increasing the planting density by 30% enhanced grain yield by 13.9% and aboveground N accumulation by 15.3%.Under reduced water and N inputs,increasing the maize density by 30% enhanced N uptake efficiency and N partial factor productivity,and it also compensated for the N harvest index and N metabolic related enzyme *** with W2N2D1,the N uptake efficiency and N partial factor productivity increased by 28.6 and 17.6%under W1N1D2.W1N2D2 had 8.4% higher N uptake efficiency and 13.9% higher N partial factor productivity than W2N2D1.W1N2D2 improv

关键词： water and N reduction plant density maize grain yield N uptake compensation effect