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Enhancing mechanisms of N-doped biomass carbon on the vanadium-based catalyst for furan degradation at low temperature

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Waste Disposal and Sustainable Energy 2024年第1期6卷 1-9页

作者： ling wang Minghui Tang Hongxian Li Jiamin Ding Juan Qiu Shengyong Lu State Key Laboratory of Clean Energy Utilization Zhejiang University38#Zheda RoadHangzhou310027China Taizhou Institute of Zhejiang University Taizhou318012China Qingshanhu Energy Research Center Zhejiang University1699 Dayuan RoadQingshanhu Science and Technology CityHangzhou311300China

Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans(PCDD/Fs)have attracted widespread concern due to their high toxicity,and their difficult manipulation in laboratories has made the research process ***,in our work,furan is selected as the model compound owing to the same structure of a central oxygenate *** catalytic oxidation is regarded as an effective and applicable method for the abatement of PCDD/Fs,the synthesis of low-temperature catalysts is still a challenging problem in practical *** this situation,we prepared a novel V_(2)O_(5)/TiO_(2)catalyst modified with N-doped hierarchical porous carbon(NHPC)via a wet impregnation *** V/T-1%NHPC catalyst could achieve expectant low-temperature performances with 50%furan conversion at 150℃and a complete conversion at 200℃,which decreased 23℃and 40℃compared to the V/T catalyst ***,the addition of NHPC presented lifting chemical stability during long-time *** addition of NHPC in V/T catalysts decreased the formation of crystalline V_(2)O_(5) and increased the percentages of V^(5+)and O_(lat),which improved the utilization of vanadium ions and the catalytic ***,the higher binding energy shift of O_(lat) implied more reaction possibility with other oxidise ***,this work proved the lifting catalytic activity by the interaction between catalysts and NHPC,and proposed the promoting effects of the N *** results showed that the content of the pyridinic N and graphitic N in NHPC changed after combining with V/T catalyst,which played crucial roles in the excellent catalytic ***,this work provides comprehensive research of the V/T-1%NHPC catalyst toward furan oxidation at low temperature and explain the effects of N-doped biomass carbon in catalytic activity clearly,which gave a new thought to design low-temperature catalysts in PCDD/Fs ***,the internal functional mech

关键词： Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans Furan Low-temperature catalyst V_(2)O_(5)/TiO_(2)catalyst N-doped

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Regulation effects of water and nitrogen on yield,water,and nitrogen use efficiency of wolfberry

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Journal of Arid Land 2024年第1期16卷 29-45页

作者： GAO Yalin QI Guangping MA Yanlin yin Minhua wang Jinghai wang Chen TIAN Rongrong XIAO Feng LU Qiang wang Jianjun College of Water Conservancy and Hydropower Engineering Gansu Agricultural UniversityLanzhou 730070China Jingtaichuan Electric Power Irrigation Water Resource Utilization Center in Gansu Province Baiyin 730900China

Wolfberry(Lycium barbarum L.)is important for health care and ecological ***,it faces problems of low productivity and resource utilization during *** reasonable models for water and nitrogen management is important for solving these *** on field trials in 2021 and 2022,this study analyzed the effects of controlling soil water and nitrogen application levels on wolfberry height,stem diameter,crown width,yield,and water(WUE)and nitrogen use efficiency(NUE).The upper and lower limits of soil water were controlled by the percentage of soil water content to field water capacity(θ_(f)),and four water levels,i.e.,adequate irrigation(W0,75%-85%θ_(f)),mild water deficit(W1,65%-75%θ_(f)),moderate water deficit(W2,55%-65%θ_(f)),and severe water deficit(W3,45%-55%θ_(f))were used,and three nitrogen application levels,i.e.,no nitrogen(N0,0 kg/hm^(2)),low nitrogen(N1,150 kg/hm^(2)),medium nitrogen(N2,300 kg/hm^(2)),and high nitrogen(N3,450 kg/hm^(2))were *** results showed that irrigation and nitrogen application significantly affected plant height,stem diameter,and crown width of wolfberry at different growth stages(P<0.01),and their maximum values were observed in W1N2,W0N2,and W1N3 *** weight per plant and yield of wolfberry first increased and then decreased with increasing nitrogen application under the same water *** weight per hundred grains and dry weight percentage increased with increasing nitrogen application under W0 ***,under other water treatments,the values first increased and then decreased with increasing nitrogen *** and its component of wolfberry first increased and then decreased as water deficit increased under the same nitrogen *** water use efficiency(IWUE,8.46 kg/(hm^(2)·mm)),WUE(6.83 kg/(hm^(2)·mm)),partial factor productivity of nitrogen(PFPN,2.56 kg/kg),and NUE(14.29 kg/kg)reached their highest values in W2N2,W1N2,W1N2,and W1N1 treatments.R

关键词： water deficit growth characteristics yield water and nitrogen use efficiency principal component analysis

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Cloning, Characterization and Transformation of Methyltransferase 2a Gene (Zmet2a) in Maize (Zea mays L.)

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1767-1779页

作者： Xin Qi Yu wang Xing Zhang Xiaoshuang Wei Xinyang Liu Zhennan wang Zhenhui wang Fenglou ling Faculty of Agronomy Jilin Agricultural UniversityChangchun130118China Rice Research Center Jilin Agricultural UniversityChangchun130118China

DNA methylation is an important epigenetic regulatory mechanism,it regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription factor(s)to *** this study,a novel methyltransferase 2a gene(Zmet2a)was cloned in maize and identiﬁed by polymerase chain reaction-base(PCR-base)using a bioinformatics *** Zmet2a cDNA sequence is 2739 bp long and translates to 912 amino acid *** Zmet2a protein revealed that it contains BAH and CHROMO structural domains,is a non-transmembrane protein that is hydrophilically unstable,and has no signal peptide ***,we veriﬁed the biological roles of Zmet2a using transgenic Arabidopsis overexpressing Zmet2a and Zmet2a-knockout *** Zmet2a Arabidopsis thaliana showed highly signiﬁcant advancement inﬂowering time,and Zmet2a-knockout maize showed advancement inﬂowering time,with signiﬁcant changes in several ***,these report the role of Zmet2a in the regulation ofﬂowering time,which will lay a foundation for revealing the biological function and epigenetic regulation mechanism of Zmet2a in the growth,development andﬂowering of maize.

关键词： DNA methylation methyltransferase Zea mays L ﬂowering time functional analysis

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Random Terpolymer of Carbon Dioxide,Butadiene and Epoxides:Synthesis,Functionalization and Degradability

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Chinese Journal of Chemistry 2024年第14期42卷 1630-1636页

作者： Zi wang Wuyi Zheng Sicong Yue Kaihao Chen Jun ling Xufeng Ni MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhouZhejiang310058 China Westlake Electronics Group Co. Ltd.HangzhouZhejiang310012 China

The utilization of carbon dioxide(CO_(2))as a C1 feedstock is consistently attractive,especially in the preparation of sustainable polymeric *** this contribution,a terpolymer of CO_(2),1,3-butadiene(BD)and epoxide is synthesized by scandium triflate catalyzed cationic ring-opening copolymerization ofα-ethylidene-δ-vinyl-δ-valerolactone(EVL),an intermediate derived from CO_(2)and BD,with *** obtained terpolymer with a CO_(2)content of 22 mol%has a number-average molecular weight(M_(n))up to 7.8 kg/mol and a dispersity(Đ)of *** reactivity ratios of EVL and cyclohexene oxide(CHO)are determined as 0.01 and 1.07,respectively,suggesting random characteristic of the *** preserved C=C double bonds from BD allow for the further modification of the terpolymer by photoinitiated *** yielded networks are fluorescent and *** method offers enhanced versatility to the synthesis and additional functionalization of CO_(2)-based polymers.

关键词： Ring-opening polymerization Copolymerization Carbon dioxide Butadiene Scandium triflate Fluorescence

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Juvenile cardiomyopathy with dystrophin deficiency

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Genes & Diseases 2024年第3期11卷 30-33页

作者： Yuhui Luo Qinglan Shu Yi wang Min Gu Hao Zhang Siqi Hong Rui wang Lixue yin Department of Cardiology Chongqing General HospitalChongqing 401147China Department of Cardiovascular Ultrasound and Noninvasive Cardiology Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of China(UESTC)ChengduSichuan 610072China Department of RadiologyChongqing General HospitalChongqing 401147China Department of Neurology Children's Hospital of Chongqing Medical UniversityChongqing 400014China School of Medicine Zunyi Medical UniversityZunyiGuizhou 563000China

Pseudohypertrophic muscular dystrophy is a lethal X-linked recessive neuromuscular disorder caused by mutations in the dystrophin *** gene encodes a cytoskeletal protein that is extensively expressed in muscle cells and that enables the strength,stability,and functionality of *** dystrophy can be grouped into two different categories based on the mutational rate and clinical severity,Duchenne muscular dystrophy(DMD)and Becker muscular dystrophy(BMD).DMD is the most common and the more severe type of *** patients usually become wheelchair-bound by the age of 12 years and die in their late teens to early twenties.^(1)In contrast,BMD is relatively less severe and the patients can potentially have alonger lifeexpectancy.

关键词： dystrophin dystrophy Becker

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Effect of Sonic hedgehog gene-modified bone marrow mesenchymal stem cells on graft-induced retinal gliosis and retinal ganglion cells survival in diabetic mice

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 34-41页

作者： Tong wang Hai-Chun Li Jin Ma Xi-ling Yu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhou 510060Guangdong ProvinceChina

AIM:To investigate the effects of Sonic hedgehog(Shh)gene-modified bone marrow mesenchymal stem cells(MSCs)on graft-induced retinal gliosis and retinal ganglion cells(RGCs)survival in diabetic ***:Bone marrow-derived MSCs were genetically modified with the Shh gene to generate a stably transfected cell line of Shh-modified MSCs(MSC-Shh).Intravitreal injections of MSC-Shh and green fluorescent protein-modified MSCs(MSC-Gfp;control)were administered in diabetic *** 4wk,the effects of MSC-Shh on retinal gliosis were evaluated using fundus photography,and markers of gliosis were examined by immunofluorescence and Western *** neurotrophic factors expression and RGCs survival in the host retina were evaluated using Western blotting and *** mechanisms underlying the effects of MSC-Shh was ***:A significant reduction of proliferative vitreoretinopathy(PVR)was observed after intravitreal injection of MSC-Shh compared to *** downregulation of glial fibrillary acidic protein(GFAP)was demonstrated in the host retina after MSC-Shh administration compared to *** extracellular signal-regulated kinase 1/2(ERK1/2),protein kinase B(AKT)and phosphatidylin-ositol-3-kinase(PI3K)pathways were significantly downregulated after MSC-Shh administration compared to ***-derived neurotrophic factor(BDNF)and ciliary neurotrophic factor(CNTF)levels were significantly increased in the host retina,and RGCs loss was significantly prevented after MSC-Shh ***:MSC-Shh administration reduces graft-induced reactive gliosis following intravitreal injection in diabetic *** ERK1/2,AKT and PI3K pathways are involved in this ***-Shh also increases the levels of neurotrophic factors in the host retina and promoted RGCs survival in diabetic mice.

关键词： mesenchymal stem cells Sonic hedgehog signaling reactive gliosis diabetic retinopathy retinal ganglion cells

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Integrated analysis of single-cell and bulk RNA sequencing data reveals immune-related lncRNA-mRNA prognostic signature in triple-negative breast cancer

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Genes & Diseases 2024年第2期11卷 571-574页

作者： Hongying Zhao Lei Yu Lixia wang Xiangzhe yin Kailai Liu wangyang Liu Shihua Lin Li wang College of Bioinformatics Science and Technology Harbin Medical UniversityHarbinHeilongjiang 150081China College of Biomedical Information and Engineering Hainan Medical UniversityHaikouHainan 571199China

Triple-negative breast cancer(TNBC)is an aggressive subtype characterized by extensive tumor heterogeneity,with limited treatment options and a poor prognosis.1 We used cell type annotation and trajectory analysis to identify two distinct differentiation states of epithelial cells,while tumor cells predominantly resided on one of these *** the malignant state of epithelial cells based on copy number variation,280 tumor cells were eventually identified from epithelial *** genes between tumor cells and non-tumor cells were mainly enriched in immune-related functions and pathways.

关键词： breast cancer signature

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Convolution-Transformer for Image Feature Extraction

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 87-106页

作者： Lirong yin Lei wang Siyu Lu Ruiyang wang Youshuai Yang Bo Yang Shan Liu Ahmed AlSanad Salman A.AlQahtani Zhengtong yin Xiaolu Li Xiaobing Chen Wenfeng Zheng Department of Geography and Anthropology Louisiana State UniversityBaton RougeLA70803USA School of Automation University of Electronic Science and Technology of ChinaChengdu610054China College of Computer and Information Sciences King Saud UniversityRiyadh11574Saudi Arabia College of Resources and Environmental Engineering Key Laboratory of Karst Georesources and Environment(Guizhou University)Ministry of EducationGuiyang550025China School of Geographical Sciences Southwest UniversityChongqing400715China School of Electrical and Computer Engineering Louisiana State UniversityBaton RougeLA70803USA

This study addresses the limitations of Transformer models in image feature extraction,particularly their lack of inductive bias for visual *** to Convolutional Neural Networks(CNNs),the Transformers are more sensitive to different hyperparameters of optimizers,which leads to a lack of stability and slow *** tackle these challenges,we propose the Convolution-based Efficient Transformer Image Feature Extraction Network(CEFormer)as an enhancement of the Transformer *** model incorporates E-Attention,depthwise separable convolution,and dilated convolution to introduce crucial inductive biases,such as translation invariance,locality,and scale invariance,into the Transformer ***,we implement a lightweight convolution module to process the input images,resulting in faster convergence and improved *** results in an efficient convolution combined Transformer image feature extraction *** results on the ImageNet1k Top-1 dataset demonstrate that the proposed network achieves better accuracy while maintaining high computational *** achieves up to 85.0%accuracy across various model sizes on image classification,outperforming various baseline *** integrated into the Mask Region-ConvolutionalNeuralNetwork(R-CNN)framework as a backbone network,CEFormer outperforms other models and achieves the highest mean Average Precision(mAP)*** research presents a significant advancement in Transformer-based image feature extraction,balancing performance and computational efficiency.

关键词： Transformer E-Attention depth convolution dilated convolution CEFormer

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Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models

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World Journal of Gastroenterology 2024年第14期30卷 2038-2058页

作者： Pan Zheng Xue-Yang Li Xiao-Yu Yang Huan wang ling Ding Cong He Jian-Hua Wan Hua-Jing Ke Nong-Hua Lu Nian-Shuang Li yin Zhu Department of Gastroenterology Digestive Disease HospitalThe First Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

BACKGROUND Acute pancreatitis(AP)encompasses a spectrum of pancreatic inflammatory conditions,ranging from mild inflammation to severe pancreatic necrosis and multisystem organ *** the challenges associated with obtaining human pancreatic samples,research on AP predominantly relies on animal *** this study,we aimed to elucidate the fundamental molecular mechanisms underlying AP using various AP *** To investigate the shared molecular changes underlying the development of AP across varying severity *** AP was induced in animal models through treatment with caerulein alone or in combination with lipopolysaccharide(LPS).Additionally,using Ptf1αto drive the specific expression of the hM3 promoter in pancreatic acinar cells transgenic C57BL/6J-hM3/Ptf1α(cre)mice were administered Clozapine N-oxide to induce ***,we conducted RNA sequencing of pancreatic tissues and validated the expression of significantly different genes using the Gene Expression Omnibus(GEO)*** Caerulein-induced AP showed severe inflammation and edema,which were exacerbated when combined with LPS and accompanied by partial pancreatic tissue *** with the control group,RNA sequencing analysis revealed 880 significantly differentially expressed genes in the caerulein model and 885 in the caerulein combined with the LPS *** Encyclopedia of Genes and Genomes enrichment analysis and Gene Set Enrichment Analysis indicated substantial enrichment of the TLR and NOD-like receptor signaling pathway,TLR signaling pathway,and NF-κB signaling pathway,alongside elevated levels of apoptosis-related pathways,such as apoptosis,P53 pathway,and phagosome *** significantly elevated genes in the TLR and NOD-like receptor signaling pathways,as well as in the apoptosis pathway,were validated through quantitative real-time PCR experiments in animal *** from the GEO database revealed that only MYD88 concurred in both mouse panc

关键词： Acute pancreatitis RNA-sequencing Experimental acute pancreatitis models Inflammatory Apoptosis TLR and NOD-like signaling pathways

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Hybrid electromechanical properties of hetero-doped and homogeneously bonded dual-mode pressure sensor for indoor body area network node

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Science China(Information Sciences) 2024年第1期67卷 240-253页

作者： Junbin YU Shuai XIAN Jinbiao MU Min wang yin wang Xiaojuan HOU Le ZHANG Jian HE Jiliang MU Xiujian CHOU Science and Technology on Electronic Test and Measurement Laboratory North University of China Sichuan Aerospace Fenghuo Servo Control Technology Corporation

Pressure sensors are considerably important for continuous monitoring of human movement and the surrounding environment to construct a caregiving system for the elderly living *** challenge for pressure sensors that still remains is combining self-driven,comfort,and ***,an all-in-one conformal pressure sensor(ACPS) based on a homogeneous integrated triboelectric-piezoelectric hybrid sensor is *** ACPS has dual-mode sensing properties due to coupling triboelectrification and piezoelectric effect ensuring a stable response to various external ***-coated glass microspheres and polyacrylonitrile were uniformly filleted into the silicone rubber substrate using a hetero-doping method to create a stretchable electrode layer with flexible conformal characteristics and a piezoelectric layer with excellent piezoelectric properties,***,the triboelectric layer was fabricated using the same silicone rubber,allowing ACPS to be homogeneously bonded into an all-in-one structure with reliable *** allowed various functional layers to have outstanding interface characteristics and thus improve the electrical transmission *** developed ACPS had outstanding sensitivity(1.04 V/104Pa),high linearity(about 0.984),a wide measurement range(10–700 k Pa),and can accurately and continuously distinguish multiple ***,using a homemade signal processing circuit,ACPSs can be deployed in the human body and the room as indoor body area network *** successfully applied to the remote tracking of daily dynamic home life and the remote operation of small electrical equipment,these ACPSs can achieve real-time caregiving for the elderly living *** an application area desperately needed by society,this study envisions a caregiving system for the elderly living alone without violating personal privacy.

关键词： dual-mode pressure sensor homogeneous bonding all-in-onestructure indoor body area network node elderly caregiving microsystem

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