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Submucosal esophageal abscess evolving into intramural submucosal dissection:A case report

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World Journal of Clinical Cases 2022年第29期10卷 10695-10700页

作者： Yang Jiao yin-he sikong Ai-Jun Zhang Xiu-Li Zuo Pu-Yue Gao Qing-Guo Ren Ru-Yuan Li Department of General Surgery Shandong University of Qilu Hospital(Qingdao)Qingdao 266000Shandong ProvinceChina Department of Gastroenterology Shandong University of Qilu Hospital(Qingdao)Qingdao 266000Shandong ProvinceChina Department of Gastroenterology Qilu Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina Department of Radiology Shandong University of Qilu HospitalShandong UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND here we report a rare case of submucosal esophageal abscess evolving into intramural submucosal *** SUMMARY An 80-year-old woman was admitted to our emergency department with a chief complaint of dysphagia and *** tests showed mild leukocytosis and elevated C-reactive protein *** tomography showed thickening of the esophageal *** endoscopy showed a laceration of the esophageal mucosa and a submucosal *** drainage occurred,and we could see purulent exudate from the *** closed the laceration with endoscopic *** patient did not remember swallowing a foreign body;however,she ate crabs before the symptoms *** prescribed the patient with antibiotic,and the symptoms were gradually *** months later,upper endoscopy showed that the laceration was healed,and the submucosal abscess ***,intramural esophageal dissection was *** performed endoscopic incision of the septum using dual-knife *** In conclusion,we are the first to report the case of esophageal submucosal abscess evolving into intramural esophageal *** significance of this case lies in clear presentation of the evolution process between two *** addition,we recommend that endoscopic incision be considered as one of the routine therapeutic modalities of intramural esophageal dissection.

关键词： Submucosal esophageal abscess Intramural esophageal dissection Endoscopic incision Case report

Soluble ST2:A Novel Biomarker for Diagnosis and Prognosis of Cardiovascular Disease

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当代医学科学（英文） 2024年第4期44卷 669-679页

作者： yin FENG Li-qun he Department of Cardiology Traditional Chinese and Western Medicine Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

The increasing incidence of cardiovascular disease(CVD)is a significant global health concern,affecting millions of individuals each *** diagnosis of acute CVD poses a formidable challenge,as misdiagnosis can significantly decrease patient survival *** biomarkers have played a vital role in the diagnosis and prognosis of CVDs,but they can be influenced by various factors,such as age,sex,and renal *** ST2(sST2)is a novel biomarker that is closely associated with different *** low reference change value makes it suitable for continuous measurement,unaffected by age,kidney function,and other confounding factors,facilitating risk stratification of ***,the combination of sST2 with other biomarkers can enhance diagnostic accuracy and prognostic *** review aims to provide a comprehensive overview of sST2,focusing on its diagnostic and prognostic value as a myocardial marker for different types of CVDs and discussing the current limitations of sST2.

关键词： cardiovascular disease combined biomarker diagnosis and prognosis limitations soluble ST2

Tuning heterogeneous microstructures to enhance mechanical properties of nano-TiN particle reinforced Haynes 230 composites by laser powder bed fusion

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Rare Metals 2024年第9期43卷 4548-4565页

作者： Wen-Jie Liu Hui Li Qian-Xing yin he-Jun Du School of Power and Mechanical Engineering Wuhan University The Institute of Technological Sciences Wuhan University School of Mechanical&Aerospace Engineering Nanyang Technological University

Laser powder bed fusion(LPBF) is considered to be one of the most promising additive manufacturing technologies for producing components with geometries and high geometrical precision that are unattainable by traditional technologies. The superalloy exhibits exceptional mechanical and high-temperature performances,rendering it a prime candidate for advanced aero-engine applications. Despite the high demand for LPBF-manufactured superalloys, the superalloy is one of the materials manufactured difficultly by LPBF due to their large laser absorptivity fluctuation, poor molten pool stability and sharp temperature gradient. hence, superalloys are characterized by severe pores, undesirable coarse columnar grains and poor mechanical properties. In this work, the effect of nano-Ti N particles on defects, molten pool characteristics and microstructure and performance of the composites were investigated. The 4.5 wt% Ti N/Haynes230 samples exhibited exceptional nanohardness and elastic modulus with maximum values reaching 5.53 GPa and 240.03 GPa, respectively. These superior mechanical properties were attributed to the combined effects of spatter and gas pore inhibition, grain refinement and duplex nanophases strengthening. Moreover, the stability of molten pool was enhanced, and spatter was effectively suppressed by adding nano-Ti N particles, while grain refinement and columnar to equiaxed transitions were promoted. Furthermore, the matrix exhibited a high dislocation density due to a significant hindrance of dislocation movement caused by massive nano-phases(e.g., Ti N and M23C6), resulting in the formation of extensive dislocation tangles and *** work offers novel insights into the role of nanoparticles reinforced superalloy composites by LPBF.

关键词： Composites Laser powder bed fusion Mechanical properties Microstructure Molten pool characteristics

A game-theoretic approach for federated learning:A trade-off among privacy,accuracy and energy

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Digital Communications and Networks 2024年第2期10卷 389-403页

作者： Lihua yin Sixin Lin Zhe Sun Ran Li Yuanyuan he Zhiqiang Hao Cyberspace Institute of Advanced Technology Guangzhou UniversityGuangzhou510006China School of Cyber Science and Engineering Huazhong University of Science and TechnologyWuhan430074China China Industrial Control Systems Cyber Emergency Response Team Beijing100040China

Benefiting from the development of Federated Learning(FL)and distributed communication systems,large-scale intelligent applications become *** devices not only provide adequate training data,but also cause privacy leakage and energy *** to optimize the energy consumption in distributed communication systems,while ensuring the privacy of users and model accuracy,has become an urgent *** this paper,we define the FL as a 3-layer architecture including users,agents and *** order to find a balance among model training accuracy,privacy-preserving effect,and energy consumption,we design the training process of FL as game *** use an extensive game tree to analyze the key elements that influence the players’decisions in the single game,and then find the incentive mechanism that meet the social norms through the repeated *** experimental results show that the Nash equilibrium we obtained satisfies the laws of reality,and the proposed incentive mechanism can also promote users to submit high-quality data in *** the multiple rounds of play,the incentive mechanism can help all players find the optimal strategies for energy,privacy,and accuracy of FL in distributed communication systems.

关键词： Federated learning Privacy preservation Energy optimization Game theory Distributed communication systems

Intelligent Reflecting Surface Assisted Transmission Optimization Strategies in Wireless Networks

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China Communications 2024年第4期21卷 120-135页

作者： he Xinxin Qi Xuan Meng Wei Liu Wei yin Changchuan School of Electronic Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China

Wireless Power Transfer(WPT)technology can provide real-time power for many terminal devices in Internet of Things(IoT)through millimeterWave(mmWave)to support applications with large capacity and low *** the intelligent reflecting surface(IRS)can be adopted to create effective virtual links to address the mmWave blockage problem,the conventional solutions only adopt IRS in the downlink from the Base Station(BS)to the users to enhance the received signal *** practice,the reflection of IRS is also applicable to the uplink to improve the spectral *** is a challenging to jointly optimize IRS beamforming and system resource allocation for wireless energy acquisition and information *** this paper,we first design a Low-Energy Adaptive Clustering Hierarchy(LEACH)clustering protocol for clustering and data ***,the problem of maximizing the minimum system spectral efficiency is constructed by jointly optimizing the transmit power of sensor devices,the uplink and downlink transmission times,the active beamforming at the BS,and the IRS dynamic *** solve this non-convex optimization problem,we propose an alternating optimization(AO)-based joint solution *** results show that the use of IRS dynamic beamforming can significantly improve the spectral efficiency of the system,and ensure the reliability of equipment communication and the sustainability of energy supply under NLOS link.

关键词： intelligent reflecting surface(IRS) joint optimization millimeter wave wireless information transmission(WIT) wireless power transfer(WPT)

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Modulated Degradation Rates of Bone Mineral-Like Calcium Phosphate Glass to Support the Proliferation and Osteogenic Differentiation of Bone Marrow-Derived Stem Cells

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Journal of Bionic Engineering 2024年第4期21卷 1960-1974页

作者： Lizhe he Yuye Huang Jiafei Gu Xiaoling Liu Jun yin Xiang Gao Department of Neurosurgery The First Affiliated Hospital of Ningbo UniversityNingbo315010China Center for Medical and Engineering Innovation The First Affiliated Hospital of Ningbo UniversityNingbo315010China The State Key Laboratory of Fluid Power Transmission and Control Systems Key Laboratory of 3D Printing Process and Equipment of Zhejiang ProvinceSchool of Mechanical EngineeringZhejiang UniversityHangzhou310028China Faculty of Science and Engineering University of Nottingham Ningbo ChinaNingbo315100China

With an elemental composition similar to bone mineral,and the ability to release phosphorus and calcium that benefit bone regeneration,Calcium Phosphate Glass(CPG)serves as a promising component of bone tissue engineering ***,the degradation of CPG composites typically results in increased acidity,and its impact on bone-forming activity is less *** this work,we prepared 3D-printed composite scaffolds comprising CPG,Poly-ε-caprolactone(PCL),and various Magnesium Oxide(MgO)*** the MgO content effectively suppressed the degradation of CPG,maintaining a physiological pH of the degradation *** the degradation of CPG/PCL scaffolds resulted in upregulated apoptosis of Rat Bone Marrow-derived Stem Cells(rBMSC),scaffolds containing MgO were free from these negative impacts,and an optimal MgO content of 1 wt%led to the most pronounced osteogenic differentiation of *** work demonstrated that the rapid degradation of CPG impaired the renewability of stem cells through the increased acidity of the surrounding media,and MgO effectively modulated the degradation rate of CPG,thus preventing the negative effects of rapid degradation and supporting the proliferation and osteogenic differentiation of the stem cells.

关键词： Phosphate glass Polymer composites 3D printing Bone tissue engineering Scaffolds

Strengthening mechanism and forming control of linear friction welded GH4169 alloy joints

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Chinese Journal of Aeronautics 2024年第4期37卷 609-626页

作者： Yu SU Xiawei YANG Tingxi MENG Xinyuan he Dong WU Wenya LI Shuo yin State Key Laboratory of Solidification Processing School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Shaanxi Key Laboratory of Friction Welding Technologies School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Department of Mechanical Manufacturing and Biomedical EngineeringParsons BuildingTrinity College DublinThe University of DublinDublin 2Ireland

Numerical simulation and experimental research on Linear Friction Welding(LFW) for GH4169 superalloy were carried out. Based on the joint microstructure and mechanical properties,a suitable welding process was determined, which provided an important theoretical basis for the manufacture and repair of aeroengine components such as the superalloy blisk. The results show that the joint strain rate gradually increases with the increase of welding frequency, and the deformation resistance of the thermoplastic metal increases in the welding process, resulting in the interface thermoplastic metal not being extruded in time to form a flash, so the joint shortening amount gradually decreases. The thermoplastic metal in the center of the welding surface is kept at high welding temperature for a long time, resulting in the decrease of the joint strength. The microhardness of the joint shows a “W” distribution perpendicular to the weld, and most of the joints break in the Thermo-Mechanically Affected Zone(TMAZ) with high tensile strength and low *** the welding area is increased without changing the aspect ratio of the welding surface, the interface peak temperature increases gradually, and the joint shortening amount decreases with the increase of the welding interface size.

关键词： Linear Friction Welding(LFW) Microstructure Mechanical properties Numerical simulation Joint shortening amount

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Simultaneous removal of sulfur dioxide and nitrogen oxide from flue gas by phosphorus sludge:The performance and absorption mechanism

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Chinese Journal of Chemical Engineering 2024年第1期65卷 212-221页

作者： Yuanyuan yin Xujun Wang Lei Xu Binbin he Yunxiang Nie Yi Mei Faculty of Chemical Engineering Kunming University of Science and TechnologyKunming 650500China Yunnan Provincial Key Laboratory of Energy Saving in Phosphorus Chemical Engineering and New Phosphorus Materials Kunming 650500China The Higher Educational Key Laboratory for Phosphorus Chemical Engineering of Yunnan Province Kunming 650500China

Developing low-cost and green simultaneous desulfurization and denitrification technologies is of great significance for sulfur dioxide(SO_(2))and nitrogen oxide(NO_(x))emission control at low temperatures,especially for small and medium-sized coal-fired boilers and ***,phosphorus sludge,an industrial waste from the production process of yellow phosphorus,has been developed to simultaneously eliminate SO_(2)and NO_(x)from coal-fired flue *** key factors affecting the experimental results indicate that desulfurization and denitrification efficiency of over 95%can be achieved at a low temperature of 55℃.Further,the absorption mechanism was investigated by characterizing the solid and liquid phases of the phosphorus sludge during the absorption *** efficient removal of SO_(2)is attributed to the abundance of iron(Fe^(3+))and manganese(Mn^(2+))in the ***_(2)can be rapidly catalyzed and converted to SO_(4)^(2-)by *** key to NOx removal is the oxidation of NO toward watersoluble high-valent nitrogen oxides by oxidizing reactive substances induced via yellow phosphorus,which are then absorbed by water and converted to NO_(3)^(-).Meanwhile,yellow phosphorus is oxidized to phosphoric acid(H_(3)PO_(4)).The spent absorption slurry can be reused through wet process phosphoric acid production,as it contains sulfuric acid(H_(2)SO_(4)),nitric acid(HNO_(3)),and H_(3)PO_(4).Accordingly,this is a technology with broad application prospects.

关键词： Absorption Oxidation Multiphase reaction Phosphorus sludge Yellow phosphorus Low temperature

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Unraveling the complexity of polycystic ovary syndrome with animal models

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Journal of Genetics and Genomics 2024年第2期51卷 144-158页

作者： Huanju Liu Mixue Tu Zhiyong yin Dan Zhang Jun Ma Feng he Center for Genetic Medicine The Fourth Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310058China Key Laboratory of Women's Reproductive health of Zhejiang Province and Department of Reproductive Endocrinology Women's HospitalZhejiang University School of MedicineHangzhouZhejiang 310006China Zhejiang Provincial Clinical Research Center for Child health Women's HospitalZhejiang University School of MedicineHangzhouZhejiang 310006China Clinical Research Center on Birth Defect Prevention and Intervention of Zhejiang Province HangzhouZhejiang 310006China Institute of Genetics Zhejiang University International School of MedicineHangzhouZhejiang 310058China Zhejiang Provincial Key Laboratory of Genetic and Developmental Disorder HangzhouZhejiang 310058China

Polycystic ovary syndrome (PCOS) is a highly familial and heritable endocrine disorder. Over half of the daughters born to women with PCOS may eventually develop their own PCOS-related symptoms. Progress in the treatment of PCOS is currently hindered by the complexity of its clinical manifestations and incomplete knowledge of its etiopathogenesis. Various animal models, including experimentally induced, naturally occurring, and spontaneously arising ones, have been established to emulate a wide range of phenotypical and pathological traits of human PCOS. These studies have led to a paradigm shift in understanding the genetic, developmental, and evolutionary origins of this disorder. Furthermore, emerging evidence suggests that animal models are useful in evaluating state-of-the-art drugs and treatments for PCOS. This review aims to provide a comprehensive summary of recent studies of PCOS in animal models, highlighting the power of these disease models in understanding the biology of PCOS and aiding high-throughput approaches.

关键词： Polycystic ovary syndrome Animal model Genetc manipulation Developmnental progtanning Drug screening