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Effects of sex on fat deposition through gut microbiota and short-chain fatty acids in weaned pigs

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Animal Nutrition 2024年第2期17卷 100-109页

作者： Linfang Yao Bo Wang Yu Wang Jie Bai yiming gao Xintong Ru Chongpeng Bi Jianping Li Anshan Shan College of Animal Science and Technology Northeast Agricultural University

Nitrogen pollution resulting from excessive feed consumption poses a significant challenge for modern swine production. Precision nutrition technology seems to be an effective way to solve this problem;therefore, understanding the law of pig body composition deposition is a prerequisite. This study investigated the sex effects on growth performance, body composition, nutrient deposition, gut microbiota, and short-chain fatty acids(SCFA) in weaned piglets. Eighty weaned pigs were randomly allocated to 2 treatments according to the sex of pigs. An individual pig was considered as a treatment *** body weights(BW 5, 7, 11, 15, 20, and 25 kg) were chosen as experimental points; for each point 10piglets close to the average BW(5 males and 5 females) were slaughtered, and there was one growth phase between each 2 BW points. Results indicated that the males had higher average daily gain(ADG)and average daily feed intake(ADFI) compared to the females(P < 0.05) at growth phases 15 to 20 kg BW and 20 to 25 kg BW. Meanwhile, males at 20 kg BW had higher body fat content than females(P < 0.10).Males showed a higher body fat(P < 0.05) deposition rate at phase 15 to 20 kg BW(P < 0.05) than females. For pigs at 20 kg BW, the relative abundance of Ruminococcaceae UCG-005, Clostridium, Christensenellaceae＿R-7＿group, and Peptostreptococcaceae was significantly increased in males(P < 0.05) but that of Bifidobacterium was decreased(P < 0.05). At 25 kg BW, the relative abundance of Ruminococcaceae＿NK4A214＿group, Fibrobacter, Ruminococcaceae UCG-009, Ralstonia, Klebsiel, and Christensenellaceae＿R-7＿group in males was higher when compared with females(P < 0.05). In terms of SCFA, females exhibited higher concentrations of propionate compared to males(P < 0.05). The results of the current study indicated that sex influenced fat deposition through changes in the composition of gut microbiota and the content of SCFA, which has significant implications for the realization of precisio

关键词： Sex Body composition Nutrient deposition Gut microbiota Short-chain fatty acid Weaned piglet

Ultrasound-assisted isolation:A new method to isolate stromal vascular fraction

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第1期6卷 8-15页

作者： yiming gao Xiaojie Zhang Poh-Ching Tan Yun Xie Peiqi Zhang Tianyu Zhang Qingfeng Li Shuangbai Zhou Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai200011China Department of Burns and Plastic Surgery Shanghai Changzheng HospitalShanghai200003China College of Life Sciences Shanghai Normal UniversityShanghai200233China

Background:The stromal vascular fraction(SVF),a cluster of stem and progenitor cells isolated from adipose tissue,holds significant promise for application in regenerative ***,the existing methods for SVF isolation are time-consuming and ***,in this study,we explored a new method of SVF extrac-tion-ultrasound-assisted SVF isolation(USASI)-and compared the viability and characteristics of SVF isolated using different ***:SVF extraction methods using different combinations of ultrasound power,ultrasound time,collagenase dosage,and collagenase digestion time were compared with those of the control group(collagenase digestion method).The cell yield and vitality of the SVF were evaluated via cell counting and trypan blue *** cell components and immunophenotypes of freshly isolated SVF were analyzed using flow *** prolifer-ative capacity and differentiation potential of the SVF were also ***:Ultrasonication at 95 W-20 kHz for 30 s followed by digestion with 0.15%collagenase for 30 min was identified as the most suitable parameter for the USASI method in isolating SVF,as recommended based on the evaluation of various tested *** USASI method significantly reduced the collagenase dosage and shortened the digestion *** to the collagenase digestion method,the USASI method had a higher cell yield and cell viability,with no adverse effects on cell components,proliferative capacity,or multipotential differentiation ***:With reduced processing time,lower collagenase dosage,and increased cell yield without impairing the viability and characteristics of SVF,USASI holds the potential to emerge as a time-saving and cost-effective method for future clinical applications.

关键词： Stromal vascular fractions SVF isolation Mechanical force Ultrasound

二元氯化物熔盐纳米流体在方腔内熔化过程的数值模拟

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储能科学与技术 2024年第3期13卷 1030-1035页

作者：田禾青高艺明周俊杰郑州大学机械与动力工程学院河南郑州450001

在熔盐中添加微纳颗粒形成纳米流体是一种强化熔盐储热材料热物性的有效方法。本工作利用Fluent软件对二元氯化物熔盐(52NaCl-48CaCl_(2),摩尔分数)及其掺杂Mg的纳米流体在二维正方形腔体内的熔化过程进行了数值模拟,分析了熔盐在方腔... 详细信息

在熔盐中添加微纳颗粒形成纳米流体是一种强化熔盐储热材料热物性的有效方法。本工作利用Fluent软件对二元氯化物熔盐(52NaCl-48CaCl_(2),摩尔分数)及其掺杂Mg的纳米流体在二维正方形腔体内的熔化过程进行了数值模拟,分析了熔盐在方腔内的熔化过程以及纳米颗粒的掺杂对腔体内熔盐熔化过程的影响。结果表明,在熔盐及其纳米流体的整个熔化过程中,主要传热形式经历热传导-自然对流-热传导三个阶段。纳米颗粒的掺杂增加了熔盐的传热速率,缩短了熔盐熔化过程所用的时间。与纯二元氯化物熔盐相比,掺杂1%(质量分数)和2%Mg的熔盐纳米流体的熔化时间分别缩短了11.34%和19.92%,固液转变时间分别缩短了33.3%和43.0%。

关键词：熔盐纳米流体熔化数值模拟

补脾益肾通络方治疗G1A2期糖尿病肾病临床研究

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辽宁中医杂志 2024年第9期51卷 45-48页

作者：臧春雪高艺铭高天舒辽宁中医药大学附属医院辽宁沈阳110033 中国医科大学第一临床学院辽宁沈阳110122

目的探讨补脾益肾通络方对G1A2期糖尿病肾病(diabetic kidney disease,DKD)患者的临床疗效。方法选取2019年12月—2021年11月在辽宁中医药大学附属医院内分泌科门诊或住院的DKD患者共106例,按随机数字表法分为对照组与观察组各53例。对... 详细信息

目的探讨补脾益肾通络方对G1A2期糖尿病肾病(diabetic kidney disease,DKD)患者的临床疗效。方法选取2019年12月—2021年11月在辽宁中医药大学附属医院内分泌科门诊或住院的DKD患者共106例,按随机数字表法分为对照组与观察组各53例。对照组予西医常规治疗,观察组在对照组基础上联合补脾益肾通络方口服,共12周。比较两组患者治疗后有效率、治疗前后尿白蛋白/尿肌酐(urinary albumin/urinary creatinine,UACR)、α1微球蛋白(α1-microglobulin,α1-MG)、β2-微球蛋白(β2-microglobulin,β2-MG)、N-乙酰-β-D氨基葡萄糖苷酶(N-acetyl-β-D glucosaminidase,NAG)、视黄醇结合蛋白(retinol-binding protein,RBP)、肾功能、糖化血红蛋白(glycosylated hemoglobin,HbA1c)、空腹血糖(fasting blood glucose,FBG)、餐后2 h血糖(2-hour postprandial blood glucose,2 h PBG)、总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、低密度脂蛋白胆固醇(low-density lipoprotein cholesterol,LDL-C)、高密度脂蛋白(high-density lipoprotein cholesterol,HDL-C)及安全性指标。结果两组患者治疗前所有指标均具有可比性;观察组总有效率82.69%(43/52),优于对照组的68.62%(35/51),差异有统计学意义(P<0.05);与治疗前比较,两组患者治疗后UACR、α1-MG、β2-MG、NAG、RBP水平显著下降(均P<0.01)。与对照组比较,观察组治疗后UACR、β2-MG、NAG、RBP水平下降(P<0.05);两组患者治疗前后肾功能无明显变化;与治疗前比较,两组治疗后HbA1c、FBG,2 h PBG水平均下降(均P<0.01)。与对照组比较,观察组HbA1c、FBG水平下调(P<0.05);与治疗前比较,两组患者治疗后TC、TG水平显著下降(均P<0.01),LDL-C、HDL-C水平变化具有统计学意义(均P<0.05);治疗后与对照组比较,观察组TC、TG水平下降(P<0.05);两组患者安全性指标均在正常范围内,无不良反应发生。结论补脾益肾通络方治疗G1A2期DKD临床疗效显著,安全性良好,值得临床推荐。

关键词：糖尿病肾病 G1A2期临床研究补脾益肾通络方

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AI辅助设计工具在平面设计中的应用

玩具世界 2024年第5期 154-156页

作者：高一鸣天津工艺美术职业学院

20世纪50年代，科学界首次提出“人工智能”（artificial intelligence, AI）一词，随着互联网技术的不断发展，AI的应用领域越来越广泛，尤其是在设计领域。在当今的平面设计领域，AI辅助设计工具的重要性正日渐显现，其在平面设计领... 详细信息

20世纪50年代，科学界首次提出“人工智能”（artificial intelligence, AI）一词，随着互联网技术的不断发展，AI的应用领域越来越广泛，尤其是在设计领域。在当今的平面设计领域，AI辅助设计工具的重要性正日渐显现，其在平面设计领域的应用对设计师产生了深远的影响。借助于深度数据分析与前沿的机器学习算法，AI辅助设计工具正在赋能设计师们以更快速地孕育出革新的创意，并精细化他们的设计策略，同时大幅提高生产流程的效率。文章首先总结了AI辅助设计工具的优势，包括提高设计效率、改善创意、降低成本、打破专业壁垒，其次探讨了AI辅助设计工具在平面设计中的具体应用，包括在插图创作中的应用、在版式设计中的应用，最后分析了AI辅助设计工具在平面设计中的应用局限性。希望文章的研究为相关人员可以提供资料性参考。

关键词： AI辅助设计工具平面设计创新应用提高效率

Energy-efficient power allocation for NOMA heterogeneous networks with imperfect CSI

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The Journal of China Universities of Posts and Telecommunications 2022年第1期29卷 102-112页

作者： Song Xin Huang Xue gao yiming Qian Haijun School of Computer and Communication Engineering Northeastern University at QinhuangdaoQinhuangdao 066000China

In this paper,an optimal user power allocation scheme is proposed to maximize the energy efficiency for downlink non-orthogonal multiple access(NOMA)heterogeneous networks(HetNets).Considering channel estimation errors and inter-user interference under imperfect channel state information(CSI),the energy efficiency optimization problem is formulated,which is non-deterministic polynomial(NP)-hard and *** cope with this intractable problem,the optimization problem is converted into a convex problem and address it by the Lagrangian dual ***,it is difficult to obtain closed-form solutions since the variables are coupled with each ***,a Lagrangian and sub-gradient based algorithm is *** the inner layer loop,optimal powers are derived by the sub-gradient *** the outer layer loop,optimal Lagrangian dual variables are *** results show that the proposed algorithm can significantly improve energy efficiency compared with traditional power allocation algorithms.

关键词： heterogeneous networks non-orthogonal multiple access imperfect channel state information power allocation

A Tibetan Sentence Boundary Disambiguation Model Considering the Components on Information on Both Sides of Shad

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Tsinghua Science and Technology 2023年第6期28卷 1085-1100页

作者： Fenfang Li Hui Lv yiming gao Dolha Yan Li Qingguo Zhou School of Information Science and Engineering Lanzhou UniversityLanzhou 730000China Key Laboratory of China’s National Linguistic Information Technology Northwest Minzu UniversityLanzhou 730030China

Sentence Boundary Disambiguation(SBD)is a preprocessing step for natural language *** text into sentences is essential for Deep Learning(DL)and pretraining language *** punctuation marks may involve ambiguity about the sentences’beginnings and ***,the ambiguous punctuation marks must be distinguished,and the sentence structure must be correctly encoded in language *** study proposed a component-level Tibetan SBD approach based on the DL *** models can reduce the error amplification caused by word segmentation and part-of-speech *** most SBD methods have only considered text on the left side of punctuation marks,this study considers the text on both *** this study,465669 Tibetan sentences are adopted,and a Bidirectional Long Short-Term Memory(Bi-LSTM)model is used to perform *** experimental results show that the F1-score of the Bi-LSTM model reached 96%,the most efficient among the six *** are performed on low-resource languages such as Turkish and Romanian,and high-resource languages such as English and German,to verify the models’generalization.

关键词： Sentence Boundary Disambiguation(SBD) punctuation marks ambiguity Bidirectional Long Short-Term Memory(Bi-LSTM)model

Secrecy-Enhancing Design for Two-Way Energy Harvesting Cooperative Networks with Full-Duplex Relay Jamming

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China Communications 2021年第5期18卷 273-284页

作者： Siyang Xu Xin Song yiming gao Suyuan Li Jing Cao Zhigang Xie School of Computer Science and Engineering Northeastern UniversityShenyang 110819China Engineering Optimization and Smart Antenna Institute Northeastern University at QinhuangdaoQinhuangdao 066004China School of Mathematics and Information Science and Technology Hebei Normal University of Science and TechnologyQinhuangdao 066004China

To guarantee secure information transmission within two sources,a full-duplex(FD)relay jamming scheme for two-way energy harvesting(EH)cooperative networks is proposed,in which the relay can achieve simultaneous information reception and jamming *** EH relay node scavenges energy from two source signals,and then,uses the harvested energy for information relaying and jamming transmission by the power splitting(PS)*** multiple eavesdroppers,the nonconvex optimization for maximizing the smaller bidirectional secrecy rates is formulated by jointly optimizing the power allocation and PS ***,an iterative algorithm based on successive convex approximation and alternate search method is proposed to solve this *** results verify the proposed iterative algorithm and show that the proposed jamming scheme can achieve substantial performance gain than other conventional schemes.

关键词： physical layer security two-way EH cooperative networks FD relay jamming minimum guaranteed secrecy rate

Upper and Lower Bounds of the α-Universal Triple I Method for Unified Interval Implications

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Computers, Materials & Continua 2024年第4期79卷 1063-1088页

作者： yiming Tang Jianwei gao Yifan Huang School of Computer and Information Hefei University of TechnologyHefei230601China Department of Electrical and Computer Engineering University of AlbertaEdmontonAB T6R 2V4Canada

Theα-universal triple I(α-UTI)method is a recognized scheme in the field of fuzzy reasoning,whichwas proposed by our research group *** robustness of fuzzy reasoning determines the quality of reasoning algorithms to a large extent,which is quantified by calculating the disparity between the output of fuzzy reasoning with interference and the output without ***,in this study,the interval robustness(embodied as the interval stability)of theα-UTI method is explored in the interval-valued fuzzy *** begin with,the stability of theα-UTI method is explored for the case of an individual rule,and the upper and lower bounds of its results are estimated,using four kinds of unified interval implications(including the R-interval implication,the S-interval implication,the QL-interval implication and the interval t-norm implication).Through analysis,it is found that theα-UTI method exhibits good interval stability for an individual ***,the stability of theα-UTI method is revealed in the case of multiple rules,and the upper and lower bounds of its outcomes are *** results show that theα-UTI method is stable for multiple rules when four kinds of unified interval implications are used,***,theα-UTI reasoning chain method is presented,which contains a chain structure with multiple *** corresponding solutions and their interval perturbations are *** is found that theα-UTI reasoning chain method is stable in the case of chain *** application examples in affective computing are given to verify the stability of theα-*** summary,through theoretical proof and example verification,it is found that theα-UTImethod has good interval robustness with four kinds of unified interval implications aiming at the situations of an individual rule,multi-rule and reasoning chain.

关键词： Fuzzy reasoning the CRI method the triple I method fuzzy implication interval robustness