检索结果-南通市图书馆

Health Risk Assessment of Employees Exposed to Chlorination By-products of Recreational Water in Large Amusement Parks in Shanghai

引用

Biomedical and Environmental Sciences 2024年第8期37卷 865-875页

作者： Weizhao Cao yiming Zheng Wenxuan Zhao Lisha Shi Yunhui Zhang Lijun Zhang Jian chen Key Lab of Health Technology Assessment National Health Commission of the People’s Republic of China(Fudan University)Shanghai 200032China Key Laboratory of Public Health Safety Ministry of EducationSchool of Public HealthFudan UniversityShanghai 200032China Division of Public Health Service and Safety Assessment Shanghai Municipal Center for Disease Control and PreventionShanghai 200336China Shanghai Institute of Preventive Medicine Shanghai 200336China

Objective Chlorination is often used to disinfect recreational water in large amusement parks;however,the health hazards of chlorination disinfection by-products(DBPs)to occupational populations are *** study aimed to assess the exposure status of chlorinated DBPs in recreational water and the health risks to employees of large amusement *** Exposure parameters of employees of three large amusement parks in Shanghai were investigated using a *** typical chlorinated DBPs in recreational water and spray samples were quantified by gas chromatography,and the health risks to amusement park employees exposed to chlorinated DBPs were evaluated according to the WHO's risk assessment *** Trichloroacetic acid,dibromochloromethane,bromodichloromethane,and dichloroacetic acid were detected predominantly in recreational *** carcinogenic and non-carcinogenic risks of the five DBPs did not exceed the risk *** addition,the carcinogenic and non-carcinogenic risks of mixed exposure to DBPs were within the acceptable risk *** Typical DBPs were widely detected in recreational water collected from three large amusement parks in Shanghai;however,the health risks of DBPs and their mixtures were within acceptable limits.

关键词： Risk assessment Water Environmental health Occupational exposure Chlorinated disinfection by-product

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Epimedin B exhibits pigmentation by increasing tyrosinase family proteins expression,activity,and stability

引用

Journal of Pharmaceutical Analysis 2024年第1期14卷 69-85页

作者： chen Hong Yifan Zhang Lili Yang Haoyang Xu Kang cheng Zhi Lv Kaixian chen yiming Li Huali Wu Department of TCM Chemistry School of PharmacyShanghai University of Traditional Chinese MedicineShanghai200000China Department of Dermatology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai200000China International Education College Shanghai University of Traditional Chinese MedicineShanghai200000China Shanghai Inoherb Cosmetics Co. Ltd.Shanghai200000China

Epimedin B(EB)is one of the main flavonoid ingredients present in Epimedium brevicornum Maxim.,a traditional herb widely used in *** previous study showed that EB was a stronger inducer of melanogenesis and an activator of tyrosinase(TYR).However,the role of EB in melanogenesis and the mechanism underlying the regulation remain ***,as an extension to our previous investigation,we provide comprehensive evidence of EB-induced pigmentation in vivo and in vitro and elucidate the melanogenesis mechanism by assessing its effects on the TYR family of proteins(TYRs)in terms of expression,activity,and *** results showed that EB increased TYRs expression through microphthalmia-associated transcription factor-mediated p-Akt(referred to as protein kinase B(PKB))/glycogen synthase kinase 3β(GSK3β)/β-catenin,p-p70 S6 kinase cascades,and protein 38(p38)/mitogen-activated protein(MAP)kinase(MAPK)and extracellular regulated protein kinases(ERK)/MAPK pathways,after which EB increased the number of melanosomes and promoted their maturation for melanogenesis in melanoma cells and human primary melanocytes/skin ***,EB exerted repigmentation by stimulating TYR activity in hydroquinone-and N-phenylthiourea-induced TYR inhibitive models,including melanoma cells,zebrafish,and ***,EB ameliorated monobenzone-induced depigmentation in vitro and in vivo through the enhancement of TYRs stability by inhibiting TYR misfolding,TYR-related protein 1 formation,and retention in the endoplasmic reticulum and then by downregulating the ubiquitination and proteolysis *** data conclude that EB can target TYRs and alter their expression,activity,and stability,thus stimulating their pigmentation function,which might provide a novel rational strategy for hypopigmentation treatment in the pharmaceutical and cosmetic industries.

关键词： Epimedin B Melanosome Tyrosinase Melanogenesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Instance segmentation from small dataset by a dual-layer semantics-based deep learning framework

引用

Science China(Technological Sciences) 2024年第9期67卷 2817-2833页

作者： chen yiming LI JianWei HU XiaoBing LIU YiRui MA JianKai XING chen LI JunJie WANG ZhiJun WANG Jincheng State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China

Efficient and accurate segmentation of complex microstructures is a critical challenge in establishing process-structure-property(PSP) linkages of materials. Deep learning(DL)-based instance segmentation algorithms show potential in achieving this ***, to ensure prediction reliability, the current algorithms usually have complex structures and demand vast training *** overcome the model complexity and its dependence on the amount of data, we developed an ingenious DL framework based on a simple method called dual-layer semantics. In the framework, a data standardization module was designed to remove extraneous microstructural noise and accentuate desired structural characteristics, while a post-processing module was employed to further improve segmentation accuracy. The framework was successfully applied in a small dataset of bimodal Ti-6Al-4V microstructures with only 112 samples. Compared with the ground truth, it realizes an 86.81% accuracy IoU for the globular αphase and a 94.70% average size distribution similarity for the colony structures. More importantly, only 36 s was taken to handle a 1024 × 1024 micrograph, which is much faster than the treatment of experienced experts(usually 900 s). The framework proved reliable, interpretable, and scalable, enabling its utilization in complex microstructures to deepen the understanding of PSP linkages.

关键词： instance segmentation dual-layer semantics deep learning small dataset Ti-6Al-4V

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Crossroads:Pathogenic role and therapeutic targets of neutrophil extracellular traps in rheumatoid arthritis

引用

BIOCELL 2024年第1期48卷 9-19页

作者： YANG LI JIAN LIU YUEDI HU chenGZHI CONG yiming chen QIAO ZHOU Department of Rheumatology The First Affiliated Hospital of Anhui University of Chinese MedicineHefei230031China First Clinical Medical School Anhui University of Chinese MedicineHefei230031China Institute of Rheumatology Anhui Academy of Chinese MedicineHefei230031China

Rheumatoid arthritis(RA)is a prevalent autoimmune disease whose main features include chronic synovial inflammation,bone destruction,and joint *** are often considered to be the first responders to inflammation and are a key presence in the inflammatory milieu of *** extracellular traps(NETs),a meshwork of DNA-histone complexes and proteins released by activated neutrophils,are widely involved in the pathophysiology of autoimmune diseases,especially RA,in addition to playing a key role in the neutrophil innate immune *** have been found to be an important source of citrullinated autoantigen antibodies and inflammatory factor release,which can activate RA synovial fibroblasts(FLS)and cause joint *** article reviews the role of NETs in the pathophysiology of RA,demonstrating the application of multiple molecules with various therapies,with a view to informing the discovery and development of novel biomarkers and therapeutic targets for RA.

关键词： Rheumatoid arthritis Neutrophil extracellular traps Review

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Predict the evolution of mechanical property of Al-Li alloys in a marine environment

引用

Defence Technology（防务技术） 2024年第1期31卷 557-566页

作者： Wei Li Lin Xiang Guang Wu Hongli Si Jinyan chen yiming Jin Yan Su Jianquan Tao Chunyang Huang State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100036China Chongqing Innovation Center Beijing Institute of TechnologyChongqing400044China First Research Institute of the Ministry of Public Security for PR China Beijing100036China Southwest Technology and Engineering Research Institute Chongqing400039China

The ocean is one of the essential fields of national defense in the future,and more and more attention is paid to the lightweight research of Marine equipment and *** study it is to develop a Machine learning(ML)-based prediction method to study the evolution of the mechanical properties of Al-Li alloys in the marine *** obtained the mechanical properties of Al-Li alloy samples under uniaxial tensile deformation at different exposure times through Marine exposure *** obtained the strain evolution by digital image correlation(DIC).The strain field images are voxelized using 2D-Convolutional Neural Networks(CNN)autoencoders as input data for Long Short-Term Memory(LSTM)neural ***,the output data of LSTM neural networks combined with corrosion features were input into the Back Propagation(BP)neural network to predict the mechanical properties of Al-Li *** main conclusions are as follows:*** variation law of mechanical properties of2297-T8 in the Marine atmosphere is *** the increase in outdoor exposure test time,the tensile elastic model of 2297-T8 changes slowly,within 10%,and the tensile yield stress changes significantly,with a maximum attenuation of 23.6%.*** prediction model can predict the strain evolution and mechanical response simultaneously with an error of less than 5%.*** study shows that a CNN/LSTM system based on machine learning can be built to capture the corrosion characteristics of Marine exposure *** results show that the relationship between corrosion characteristics and mechanical response can be predicted without considering the microstructure evolution of metal materials.

关键词： Marine environment Al-Li alloy Machine learning Corrosion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-dimensional multiplexing optical secret sharing framework with cascaded liquid crystal holograms

引用

Opto-Electronic Advances 2024年第1期7卷 28-35页

作者： Keyao Li yiming Wang Dapu Pi Baoli Li Haitao Luan Xinyuan Fang Peng chen Yanqing Lu Min Gu Institute of Photonic Chips University of Shanghai for Science and TechnologyShanghai 200093China Centre for Artificial-Intelligence Nanophotonics School of Optical-Electrical and Computer EngineeringUniversity of Shanghai for Science and TechnologyShanghai 200093China National Laboratory of Solid State Microstructures and College of Engineering and Applied SciencesNanjing UniversityNanjing 210093China

Secret sharing is a promising technology for information encryption by splitting the secret information into different ***,the traditional scheme suffers from information leakage in decryption process since the amount of available information channels is ***,we propose and demonstrate an optical secret sharing framework based on the multi-dimensional multiplexing liquid crystal(LC)*** LC holograms are used as spatially separated shares to carry secret *** polarization of the incident light and the distance between different shares are served as secret keys,which can significantly improve the information security and ***,the decryption condition is also restricted by the applied external voltage due to the variant diffraction efficiency,which further increases the information *** implementation,an artificial neural network(ANN)model is developed to carefully design the phase distribution of each LC *** the advantage of high security,high capacity and simple configuration,our optical secret sharing framework has great potentials in optical encryption and dynamic holographic display.

关键词： holographic encryption optical secret sharing cascaded liquid crystal hologram multi-dimensional multiplexing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-performance and wavelength-transplantable on-chip Fourier transform spectrometer using MEMS in-plane reconfiguration

引用

Photonics Research 2024年第8期12卷 1730-1740页

作者： HENG chen HUI ZHANG JING ZHOU chen MA QIAN HUANG HANXING WANG QINGHUA REN NAN WANG chenGKUO LEE yiming MA School of Microelectronics Shanghai UniversityShanghai 201800China Shanghai Collaborative Innovation Center of Intelligent Sensing Chip Technology Shanghai UniversityShanghai 201800China Department of Electrical and Electronic Engineering The Hong Kong Polytechnic UniversityHong Kong 999077China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Center for Intelligent Sensors and MEMS(CISM) National University of SingaporeSingapore 117608Singapore

On-chip spectrometers with high compactness and portability enable new applications in scientific research and industrial *** transform(FT)spectrometers have the potential to realize a high signal-to-noise *** we propose and demonstrate a generalized design for high-performance on-chip FT *** spectrometer is based on the dynamic in-plane reconfiguration of a waveguide coupler enabled by an integrated comb-drive actuator *** electrostatic actuation intrinsically features ultra-low power *** coupling gap is crucial to the spectral *** in-plane reconfiguration surmounts the lithography accuracy limitation of the coupling gap,boosting the resolution to 0.2 nm for dual spectral spikes over a large bandwidth of 100 nm(1.5–1.6μm)within a compact footprint of 75μm×1000μ***,the in-plane tuning range can be large enough for arbitrary wavelengths to ensure the effectiveness of spectrum *** a result,the proposed spectrometer can be easily transplanted to other operation bands by simply scaling the structural *** a proof-of-concept,a mid-infrared spectrometer is further demonstrated with a dual-spike reconstruction resolution of 1.5 nm and a bandwidth of 300 nm(4–4.3μm).

关键词： waveguide tuning lithography

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Expansion of the Kernels for 3D Elastic Fast Multipole BEM

The Expansion of the Kernels for 3D Elastic Fast Multipole B...

引用

The second Asia-Pacific International Conference on Computational Methods in Engineering（ICOME2006）

作者： yiming chen 1 Weiwei Wang 1 Guangxian Shen 2 Hailian Gui 1 Lamei Tong 1 1 College of Science Yanshan University Qinhuangdao 066004 China 2 College of Mechanical Engineering Yanshan University Qinhuangdao 066004 China

In comparision with finite element method （FEM）,the boundary element method （BEM） has unique advantages of dimension reduction and high accuracy. But the conventional BEM is not efficient for large scale problems because of the dense and nonsymmetric matrix formed by BEM. Moreover,for a conventional calculation,O（N3）or O（N2） operations O（N2）memory are required,where N is the number of degrees of freedom （DOF）. However,both can be reduced for the Fast Multipole Element Method （FM-BEM）.Since the FM-BEM is suitable for large scale problems,the FM-BEM has been investigated by many researchers recently. We further the research production of Shen Guangxian’s research group in Yanshan University,that is,the 3D elastic FM-BEM,the program-pattern multipole BEM for frictional contact,the multipole BEM for 3D elasto-plastic contact with friction,and the 3D multipole BEM for potential problems. The above-mentioned methods have been developed,the theorical methods and experimentation results can be obtained,the FM-BEM has been applied to large scale engineering problems successfully. Firstly,we give the BEM formulation for 3D elasticity problems,also give the formulation of stress in the domain,and relevant basic kernels. Secondly,we introduce the basic solutions for 3D elasticity problems,and give the fast multipole method （FMM） expansions of the basic solutions,which have been used for 3D elasticity problems and rolling problems. Finally,we use the mathematical method of the FM-BEM for 3D elasticity problems,and the knowledge of the partial differential coefficient derive the FMM expansions of the kernels for 3D elastic FM-BEM,and complete the mathematical methods of the FM-BEM for 3D elasticity problems. We can obtain that the FMM expansions of kernels for 3D elasticity problems,this FMM expansions can be written as the form of 1/ R ,hence,we can use the mathematical methods of the FM-BEM for 3D elasticity problems,and the computation of the kernels can be simplied,the comput

关键词： Fast Muotipole Boundary Element Method 3D elasticity problems kernels

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Oxygen self-doping pyrolyzed polyacrylic acid as sulfur host with physical/chemical adsorption dual function for lithium-sulfur batteries

引用

Chinese Chemical Letters 2024年第7期35卷 473-479页

作者： Yan Wang Huixin chen Fuda Yu Shanyue Wei Jinhui Song Qianfeng He yiming Xie Miaoliang Huang Canzhong Lu Engineering Research Center of Environment-Friendly Functional Materials Ministry of EducationInstitute of Materials Physical ChemistryHuaqiao UniversityXiamen 361021China CAS Key Laboratory of Design and Assembly of Functional Nanostructures and Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstitutesChinese Academy of SciencesXiamen 361021China

Lithium-sulfur(Li-S)batteries with high theoretical capacity and energy density need to solve problems such as the high decomposition energy barrier of Li_(2)S and large volume change of sulfur in the charging process caused by the shuttle effect before practical ***,a green synthesis method is used to prepare polyacrylic acid(PAA)superabsorbent material,and then the pyrolyzed PAA(P/PAA)material is obtained as the positive electrode of Li-S *** functional calculation reveals that the oxygen self-doping pyrolyzed polyacrylic acid(P/PAA)delivered stronger binding energy toward Li2S species in carbonyl C=O than that of graphite powder(GP)which are-1.58 eV and-1.02 eV,*** with the distribution of relaxation time analysis and the in-situ electrochemical impedance approach,it is further demonstrated that the designed P/PAA as sulfur host plays a physical/chemical adsorption dual function in maintaining the stability and rate performance of *** an initial discharge capacity of 1258 mAh/g at 0.1 C and a minimal capacity decline of 0.05%per cycle even after 800 cycles at 0.5 C,the produced cathode demonstrated outstanding electrochemical *** average Coulombic efficiency is nearly 100%.The P/PAA electrodes may typically retain 96%of their capacity while declining on average only 0.033%per cycle after 130 cycles at 3 *** effort provides a new method for the future development of heteroatomic self-doping superabsorbent with promising adsorption properties for polysulfides as cathode materials of Li-S batteries.

关键词： Polyacrylic acid Oxygen self-doping Green synthetic Pore mesh polymer cathodes Lithium-sulfur batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-performance wearable bimetallic nanowire-assisted composite foams for efficient electromagnetic interference shielding,infrared stealth,and piezoresistive sensing

引用

Nano Research 2024年第7期17卷 6757-6765页

作者： Tianyi Hang Lijie Zhou chenhui Xu yiming chen Jiahui Shen Jiajia Zheng Pingan Yang Xiping Li Heng Luo Guoxiu Tong Key Laboratory of Urban Rail Transit Intelligent Operation and Maintenance Technology and Equipment of Zhejiang Province College of EngineeringZhejiang Normal UniversityJinhua 321004China School of Automation Chongqing University of Posts and TelecommunicationsChongqing 400065China State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

With the accelerated development of modern detection and communication technology,the multifunctional wearable materials with excellent electromagnetic interference(EMI)shielding,infrared stealth,and human monitoring for improving military combat capability have received extensive *** this work,the lightweight melamine foam(MF)@silver nanowires(AgNWs)-iron nanowires(FeNWs)(AgFe-MF)was fabricated by a vacuum-assisted dip-coating *** to the porous structure and synergistic electrical and magnetic losses,this lightweight(0.115 g/cm^(3))composite foam with an ultra-low filler content(0.62 vol.%)exhibited an ideal EMI shielding efficiency of 38.4 *** the other hand,the AgFe-MF realized a powerful multifunctional *** surface saturation temperature of the AgFe-MF reached 94.2℃under a low applied voltage of 1.8 V and remained extremely fast heating and cooling response and terrific working stability,resulting in excellent infrared stealth and camouflage ***,taking virtues of the elastic porous conductive architecture,the AgFe-MF was utilized as a piezoresistive sensor exhibiting board compressive interval of 0–1.62 kPa(50%strain)with a good sensitivity of 0.57 kPa^(−1).This work will provide new ideas and insights for developing multifunctional wearable devices in the fields of EMI shielding,thermal management,and piezoresistive sensing.

关键词： metal nanowires porous foams electromagnetic interference shielding infrared stealth wearable sensors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：