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The Effect of Moisture in Different Altitude Layers on the Eastward Propagation of MJO

Journal of Meteorological Research 2024年第3期38卷 437-452页

作者： Xiaoyu ZHU Zhong ZHONG yimin ZHU Yunying LI Yijia HU Yao HA College of Meteorology and Oceanography National University of Defense TechnologyChangsha410000China Key Laboratory for Virtual Geographic Environment School of Geography ScienceNanjing Normal UniversityNanjing210023China Jiangsu Collaborative Innovation Center for Climate Change School of Atmospheric SciencesNanjing UniversityNanjing210000China

In this study,driven by ERA5 reanalysis data,the Weather Research and Forecasting(WRF)version 4.0 was used to investigate the eastward propagation of the Madden-Julian oscillation(MJO)in the tropical atmosphere during December-February(DJF)of 2007/*** experiment with 11 cumulus parameterization schemes respectively shows that the Grell 3D scheme is one of several worse ones in describing MJO *** addition,still by use of the Grell 3D scheme,four nudging assimilation experiments for water vapor in all model vertical layers(Ndg_all),lower layers(Ndg_low),middle layers(Ndg_mid),and upper layers(Ndg_upp)were *** is found that when the water vapor in the model approaches to the observed value,the model performance for MJO activities is improved *** the four nudging simulations,Ndg_all certainly performs *** Ndg_mid is important for the MJO-filtered profiles related to moisture,Ndg_low and Ndg_upp exhibit superiority to Ndg_mid in simulating MJO eastward ***_low has advantages when MJO features are represented by zonal wind at 850 hPa and precipitation because the lower-level MJO-filtered moisture is conducive to the existence of lower-level condensational heating to the east of the MJO convective ***_upp performs better when describing the MJO eastward propagation features by outgoing longwave radiation(OLR)since it can capture the moisture and cloud top temperature of deep convection associated with MJO,as well as front Walker *** results suggest that the lower-level moisture is more important in regulating the MJO eastward propagation,and the observed maximum MJO-filtered moisture in the middle troposphere might be a phenomenon accompanying the MJO deep convection,but not a factor controlling its eastward propagation.

关键词： Madden-Julian oscillation(MJO) nudging technique Weather Research and Forecasting(WRF)model vertical moisture structure

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The evolution of robotics:research and application progress of dental implant robotic systems

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International Journal of Oral Science 2024年第2期16卷 173-185页

作者： Chen Liu Yuchen Liu Rui Xie Zhiwen Li Shizhu Bai yimin Zhao State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration Xi’anChina National Clinical Research Center for Oral Diseases Xi’anChina Shaanxi Key Laboratory of Stomatology Xi’anChina Digital Center School of StomatologyThe Fourth Military Medical UniversityXi’anChina

The use of robots to augment human capabilities and assist in work has long been an *** has been developing since the 1960s when the first industrial robot was *** technology has advanced,robotic-assisted surgery has shown numerous advantages,including more precision,efficiency,minimal invasiveness,and safety than is possible with conventional techniques,which are research hotspots and cutting-edge *** article reviewed the history of medical robot development and seminal research papers about current research *** the autonomous dental implant robotic system as an example,the advantages and prospects of medical robotic systems would be discussed which would provide a reference for future research.

关键词： robot robotic application

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Profiling of Ubiquitination Modification Sites in Talin in Colorectal Carcinoma by Mass Spectrometry

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Chemical Research in Chinese Universities 2019年第3期35卷 377-381页

作者： wang Ke QIAO Lu LI Xiaoou LI Shimeng wang yimin XU Xuesong HE Chengyan FANG Ling China-Japan Union Hospital Jilin UniversityChangchun 130033P.R.China Tumor Hospital of Jilin Province Changchun 130012P.R.China

Talin protein was partially purified from human colorectal carcinoma tissues, which was subject to tryptic digestion. Immunoaffinity precipitation with specific antibodies that recognize diglycyl-lysine(Lys) remnants from tryptic digestion of ubiquitinated peptides was used to enrich ubiquitinated sites in talin. Mass spectrometry coupled with capillary reverse-phase high-performance liquid chromatography was used to analyze tlie enriched peptides. Specifically, four peptides containing diglycyl-Lys remnants from talin, namely, TAK(ub)VLVEDTK, QQQYK(ub) FLPSELRDEH, K(ub)STVLQQQYNR, and EGILK(ub)TAK can be determined using mass spectrometric data. This study provides an analytical method for further study in tlie relationship between ubiquitination modification of talin and its biological activity in colorectal cancer tissues with different pathological processes.

关键词： Talin Ubiquitination Colorectal carcinoma Mass spectrometry

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Prevention and treatment for radiation-induced skin injury during radiotherapy

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Radiation Medicine and Protection 2020年第2期1卷 60-68页

作者： yimin wang Wenling Tu Yiting Tanga Shuyu Zhang School of Radiation Medicine and Protection and State Key Lab of Radiation Medicine and Radioprotection Soochow UniversitySuzhou215123China The Second Affiliated Hospital of Chengdu Medical College China National Nuclear Corporation 416 HospitalChengdu610051China West China School of Basic Medical Sciences&Forensic Medicine Sichuan UniversityChengdu610041China

The skin tissue has the largest area in the human body and functions as both a barrier and a *** such,it tends to be the first tissue to be *** in medical technology provide prospects as well as side effects,for example,radiation therapy for *** increasing cancer morbidity and radiation widely applied for cancer therapy,radiation-induced skin injury(RSI)has become a serious *** recent decades,research efforts have focused on the mechanisms underlying *** review summarizes the mainstream opinions on these mechanisms,including the pathological,molecular biological,and cytobiological *** reactive oxygen species(ROS),cytokines and involved signaling pathways are *** relevant aspects include radiation-induced skin fibrosis(RSF)and radiation-related skin cell ***,we review strategies for the prevention and treatment in clinical and pre-clinical studies to support the treatment of RSI during *** prevention strategies include dose control,pre-irradiation instructions,and RSI assessments,while the main treatments include physical therapy,external-use dressings or creams,biological therapy and surgical reconstruction.

关键词： Ionizing radiation Radiotherapy Radiation-induced skin injury(RSI) Radiation-induced skin fibrosis(RSF) Radiation-related skin cell senescence

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基于阻抗和功率守恒法的地铁车辆段上盖建筑车致振动预测模型研究

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振动与冲击 2022年第7期41卷 62-67,73页

作者：陶子渝汪益敏邹超华南理工大学土木与交通学院广州510641 广东工业大学土木与交通工程学院广州510006

为评价地铁车辆段上盖建筑车致振动响应对人体舒适度的影响并指导减隔振措施设计,以深圳地铁某车辆段上盖钢框架结构为对象,基于波传导理论提出了计算高效的竖向振动预测模型。该模型包含两个子模型,子模型一基于阻抗法考虑竖向振动以... 详细信息

为评价地铁车辆段上盖建筑车致振动响应对人体舒适度的影响并指导减隔振措施设计,以深圳地铁某车辆段上盖钢框架结构为对象,基于波传导理论提出了计算高效的竖向振动预测模型。该模型包含两个子模型,子模型一基于阻抗法考虑竖向振动以轴向波的形式沿结构柱向上传播,以上盖平台柱脚速度作为输入预测上盖建筑各楼层柱脚振动响应;子模型二考虑梁板组合效应,推导了梁端驱动点阻抗,利用子模型一计算得到的柱脚振动速度作为输入,基于功率守恒原理预测楼板时空平均振动响应。通过将预测模型的计算结果与现场实测结果进行对比,验证了预测模型的有效性。研究成果可为地铁车辆段上盖建筑车致振动提供高效、简便的科学预测方法和理论依据。

关键词：地铁车辆段上盖建筑车致振动预测模型波传导驱动点阻抗功率守恒

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坦克炮控系统RBF神经网络自适应鲁棒控制方法研究

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振动与冲击 2022年第24期41卷 72-78页

作者：王一珉杨国来王丽群南京理工大学机械工程学院南京210094

随着新一代坦克的发展,对其射击精度、炮口动能均提出了更高的要求,已有的坦克炮系统建模方法和控制策略已不能满足要求。为此,考虑车炮系统中非线性多因素,搭建了坦克行进间车炮系统多体动力学模型,并设计了基于RBF(radial basis funct... 详细信息

随着新一代坦克的发展,对其射击精度、炮口动能均提出了更高的要求,已有的坦克炮系统建模方法和控制策略已不能满足要求。为此,考虑车炮系统中非线性多因素,搭建了坦克行进间车炮系统多体动力学模型,并设计了基于RBF(radial basis function)神经网络补偿未建模扰动估计项的自适应鲁棒坦克炮控系统控制器。以行进间坦克的炮口扰动因素为优化目标,根据控制指令设计自适应律,实现未知系统参数的实时更新。仿真结果表明,新控制方法与传统的相比,具有更好跟踪效果和更强的鲁棒性。

关键词：车炮系统多体动力学非线性稳定系统自适应鲁棒控制神经网络机电一体化

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关于建立中国特色社会主义数据共有制的研究

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行政管理改革 2022年第5期 16-22页

作者：王益民中共中央党校(国家行政学院)信息技术部中共中央党校(国家行政学院)电子政务研究中心国家电子政务专家委员会

迈入数字文明新阶段,数据已经成为关键性、基础性生产要素,但数据管理制度较为滞后、数据市场构建面临诸多困难,导致数据确权、数据交易、数据伦理、数据算法及公平与效率等一系列相关问题凸显,亟须建立与数据时代发展相适应的数据制度... 详细信息

迈入数字文明新阶段,数据已经成为关键性、基础性生产要素,但数据管理制度较为滞后、数据市场构建面临诸多困难,导致数据确权、数据交易、数据伦理、数据算法及公平与效率等一系列相关问题凸显,亟须建立与数据时代发展相适应的数据制度体系和管理规则。本文立足当前国内外发展形势和数字化发展趋势,提出建立中国特色社会主义数据所有权制度——共有制,从而推进数据基础制度体系构建,旨在进一步激发数据要素潜能和价值,不断提高我国的数字化建设能力,创造新的国际竞争优势。

关键词：共有制数据所有权数据确权

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Impacts of Future Changes in Heavy Precipitation and Extreme Drought on the Economy over South China and Indochina

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Advances in Atmospheric Sciences 2024年第6期41卷 1184-1200,I0022-I0034页

作者： Bin TANG Wenting HU Anmin DUAN yimin LIU Wen BAO Yue XIN Xianyi YANG State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 101408China State Key Laboratory of Marine Environmental Science College of Ocean and Earth SciencesXiamen UniversityXiamen 361005China Chinese Academy of Sciences the CAS Institutes of Science and DevelopmentBeijing 101408China School of Public Policy and Management University of Chinese Academy of SciencesBeijing 101408China

Heavy precipitation and extreme drought have caused severe economic losses over South China and Indochina(INCSC)in recent *** the areas with large gross domestic product(GDP)in the INCSC region are distributed along the coastline and greatly affected by global warming,understanding the possible economic impacts induced by future changes in the maximum consecutive 5-day precipitation(RX5day)and the maximum consecutive dry days(CDD)is critical for adaptation planning in this *** on the latest data released by phase 6 of the Coupled Model Intercomparison Project(CMIP6),future projections of precipitation extremes with bias correction and their impacts on GDP over the INCSC region under the fossil-fueled development Shared Socioeconomic Pathway(SSP5-8.5)are *** indicate that RX5day will intensify robustly throughout the INCSC region,while CDD will lengthen in most regions under global *** changes in climate consistently dominate the effect on GDP over the INCSC region,rather than the change of *** only considering the effect of climate change on GDP,the changes in precipitation extremes bring a larger impact on the economy in the future to the provinces of Hunan,Jiangxi,Fujian,Guangdong,and Hainan in South China,as well as the Malay Peninsula and southern Cambodia in ***,timely regional adaptation strategies are urgent for these ***,from the sub-regional average viewpoint,over two thirds of CMIP6 models agree that maintaining a lower global warming level will reduce the economic impacts from heavy precipitation over the INCSC region.

关键词： CMIP6 heavy precipitation extreme drought South China Indochina economic impact

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Precise genome-editing in human diseases:mechanisms,strategies and applications

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1065-1085页

作者： Yanjiang Zheng Yifei Li Kaiyu Zhou Tiange Li Nathan J.VanDusen yimin Hua Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE Department of PediatricsWest China Second University HospitalSichuan UniversityChengduSichuan 610041China Department of Cardiovascular Surgery West China HospitalSichuan UniversityChengduSichuan 610041China Department of Pediatrics Herman B Wells Center for Pediatric ResearchIndiana University School of MedicineIndianapolisIN 46202USA

Precise genome-editing platforms are versatile tools for generating specific,site-directed DNA insertions,deletions,and *** continuous enhancement of these tools has led to a revolution in the life sciences,which promises to deliver novel therapies for genetic *** genome-editing can be traced back to the 1950s with the discovery of DNA’s doublehelix and,after 70 years of development,has evolved from crude in vitro applications to a wide range of sophisticated capabilities,including in vivo ***,precise genome-editing faces constraints such as modest efficiency,delivery challenges,and off-target *** this review,we explore precise genome-editing,with a focus on introduction of the landmark events in its history,various platforms,delivery systems,and ***,we discuss the landmark events in the history of precise ***,we describe the current state of precise genome-editing strategies and explain how these techniques offer unprecedented precision and versatility for modifying the human ***,we introduce the current delivery systems used to deploy precise genome-editing components through DNA,RNA,and ***,we summarize the current applications of precise genome-editing in labeling endogenous genes,screening genetic variants,molecular recording,generating disease models,and gene therapy,including ex vivo therapy and in vivo therapy,and discuss potential future advances.

关键词： precise generating editing

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Transcription factor OsSPL10 interacts with OsJAmyb to regulate blast resistance in rice

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The Crop Journal 2024年第1期12卷 301-307页

作者： Zaofa Zhong Lijing Zhong Xiang Zhu yimin Jiang Yihong Zheng Tao Lan Haitao Cui College of Life Science Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Fujian Provincial Key Laboratory of Crop Breeding by Design Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina College of Plant Protection Shandong Agricultural UniversityTai’an 271018ShandongChina

Transcription factors(TFs)play essential roles in transcriptional reprogramming during activation of plant immune responses to ***10(SQUAMOSA promoter binding protein-like10)is an important TF regulating trichome development and salt tolerance in *** we report that knockout of OsSPL10 reduces whereas its overexpression enhances rice resistance to blast ***10 positively regulates chitin-induced immune responses including reactive oxygen species(ROS)burst and callose *** show that OsSPL10 physically associates with OsJAmyb,an important TF involved in jasmonic acid(JA)signaling,and positively regulates its protein *** then prove that OsJAmyb positively regulates resistance to *** results reveal a molecular module consisting of OsSPL10 and OsJAmyb that positively regulates blast resistance.

关键词： Immunity Jasmonate Oryza sativa OsSPL10 Transcription factor

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