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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1117-1133页

作者： Pengfei DOU Hao LIU Chengshun XU Jinting WANG yilong sun Xiuli DU Department of Hydraulic Engineering Tsinghua UniversityBeijing 100084China Key Laboratory of Urban Security and Disaster Engineering of the Ministry of Education Beijing University of TechnologyBeijing 100124China

This study investigates the seismic response and failure mode of a pile-structure system in a liquefiable site by employing a numerical simulation model combined with the shaking-table results of a soil-pile-structure dynamic *** pile and soil responses obtained from the numerical simulations agreed well with the experimental *** slopes of the dynamic shear-stress-shear-strain hysteretic curves at different positions also exhibited a decreasing trend,indicating that the shear strength of the soil in all parts of the foundation *** peak acceleration of the soil and pile was not clearly amplified in the saturated sand layer but appeared to be amplified in the top *** maximum bending moments appeared in the middle and lower parts of the pile shaft;however,the shear forces at the corresponding positions were not *** can be observed from the deformation mode of the pile-group foundation that a typical bending failure is caused by an excessive bending moment in the middle of the pile shaft if the link between the pile top and cap is articulated,and sufficient attention should be paid to the bending failure in the middle of the pile shaft.

关键词： numerical simulation soil liquefaction pile foundation shaking-table experiment seismic responses failure model

长期循环荷载作用对大直径单桩水平承载特性的影响分析

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太阳能学报 2024年第3期45卷 116-121页

作者：赖踊卿孙毅龙李炜戚海峰许成顺何奔中国电建集团华东勘测设计研究院有限公司杭州310058 北京工业大学城市与工程安全减灾教育部重点实验室北京100124 温州大学建筑工程学院温州325035 浙江省软弱土地基与海涂围垦工程技术重点实验室温州325035 滨海软土地基防灾减灾技术浙江省工程研究中心温州325035

海上风力机结构体系长期经受波浪、风等水平循环荷载的作用,循环荷载的长期作用会引起桩周地基土体产生棘轮效应及形成密实沉陷区,研究长期循环荷载效应对风力机单桩承载特性的影响规律具有重要的工程意义。基于有限差分软件FLAC3D计算... 详细信息

海上风力机结构体系长期经受波浪、风等水平循环荷载的作用,循环荷载的长期作用会引起桩周地基土体产生棘轮效应及形成密实沉陷区,研究长期循环荷载效应对风力机单桩承载特性的影响规律具有重要的工程意义。基于有限差分软件FLAC3D计算平台,建立风力机单桩的数值计算模型,与既有桩基试验开展对比验证模型的有效性;随后引入长期循环荷载效应引起的桩周密实沉陷简化模型,开展海上风力机大直径单桩的承载性能对比研究,探讨考虑与未考虑密实沉陷区时桩基的变形、弯矩、p-y(土体抗力-桩基水平位移)曲线的差异,分析长期循环荷载效应对桩基承载特性的影响规律。结果表明,密实沉陷对单桩的刚性转动点位置基本无影响,但在桩基埋置的浅层区域,桩周密实沉陷区对桩基水平位移影响显著,且引起桩基弯矩发生突变。

关键词：海上风力机循环荷载桩基础承载特性

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Bioinformatic approaches of liquid–liquid phase separation in human disease

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中华医学杂志(英文版) 2024年第16期137卷 2024 Jul 19页

作者： sun Jun Chen yilong Bi Ruiye Yuan Yong Yu Haopeng Department of Thoracic Surgery and West China Biomedical Big Data Center West China Hospital Sichuan University Chengdu Sichuan China Med-X Center for Informatics Sichuan University Chengdu Sichuan China Department of Orthognathic and TMJ Surgery State Key Laboratory of Oral Diseases National Clinical Research Center for Oral Diseases West China Hospital of Stomatology Sichuan University Chengdu Sichuan China

Biomolecular aggregation within cellular environments via liquid–liquid phase separation (LLPS) spontaneously forms droplet-like structures, which play pivotal roles in diverse biological processes. These structures are closely associated with a range of diseases, including neurodegenerative disorders, cancer and infectious diseases, highlighting the significance of understanding LLPS mechanisms for elucidating disease pathogenesis, and exploring potential therapeutic interventions. In this review, we delineate recent advancements in LLPS research, emphasizing its pathological relevance, therapeutic considerations, and the pivotal role of bioinformatic tools and databases in facilitating LLPS investigations. Additionally, we undertook a comprehensive analysis of bioinformatic resources dedicated to LLPS research in order to elucidate their functionality and applicability. By providing comprehensive insights into current LLPS-related bioinformatics resources, this review highlights its implications for human health and disease.

关键词： Phase separation Liquid–liquid phase separation Disease Phase separation databases Bioinformatic tools

Influence of O-O formation pathways and charge transfer mediator on lipid bilayer membrane-like photoanodes for water oxidation

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Journal of Energy Chemistry 2024年第6期93卷 526-537,I0013页

作者： Yingzheng Li Shaoqi Zhan Zijian Deng Meng Chen yilong Zhao Chang Liu Ziqi Zhao Hongxia Ning Wenlong Li Fei Li Licheng sun Fusheng Li State Key Laboratory of Fine Chemicals Frontier Science Center for Smart MaterialsDalian University of Technology116024 DalianLiaoningChina Department of Chemistry-Ångström Uppsala UniversityBox 52375120 Uppsal1Sweden Center of Artificial Photosynthesis for Solar Fuels School of ScienceWestlake UniversityHangzhou 310024ZhejiangChina

Inspired by the function of crucial components in photosystemⅡ(PSⅡ),electrochemical and dyesensitized photoelectrochemical(DSPEC)water oxidation devices were constructed by the selfassembly of well-designed amphipathic Ru(bda)-based catalysts(bda=2,2'-bipyrdine-6,6'-dicarbonoxyl acid)and aliphatic chain decorated electrode surfaces,forming lipid bilayer membrane(LBM)-like *** Ru(bda)catalysts on electrode-supported LBM films demonstrated remarkable water oxidation performance with different O-O formation ***,compared to the slow charge transfer process,the O-O formation pathways did not determine the PEC water oxidation efficiency of the dyesensitized photoanodes,and the different reaction rates for similar catalysts with different catalytic paths did not determine the PEC performance of the ***,charge transfer plays a decisive role in the PEC water oxidation *** an indolo[3,2-b]carbazole derivative was introduced between the Ru(bda)catalysts and aliphatic chain-modified photosensitizer in LBM films,serving as a charge transfer mediator for the tyrosine-histidine pair in PSⅡ,the PEC water oxidation performance of the corresponding photoanodes was dramatically enhanced.

关键词： Water oxidation Rate determine step Dye-sensitized photoelectrochemical cell Charge transfer Artificial photosynthesis

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Balloon Angioplasty for Symptomatic Intracranial Artery Stenosis (BASIS): protocol of a prospective, multicentre, randomised, controlled trial

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Stroke & Vascular Neurology 2024年第1期9卷 66-74页

作者： Xuan sun Ming Yang Dapeng sun Guangge Peng Yiming Deng Xingquan Zhao Liping Liu Ning Ma Feng Gao Dapeng Mo Wengui Yu Yongjun Wang yilong Wang Zhongrong Miao Department of Interventional Neuroradiology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of Neurology Beijing Luhe HospitalCapital Medical UniversityBeijingChina Department of Neurology Comprehensive Stroke&Cerebrovascular CenterUniversity of California IrvineIrvineCaliforniaUSA Chinese Institute for Brain Research BeijingChina National Center for Neurological Diseases BeijingChina Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina Beijing Laboratory of Oral Health Capital Medical UniversityBeijingChina

Background The superiority of balloon angioplasty plus aggressive medical management(AMM)to AMM alone for symptomatic intracranial artery stenosis(sICAS)on efficacy and safety profiles still lacks evidence from randomised controlled trials(RCTs).Aim To demonstrate the design of an RCT on balloon angioplasty plus AMM for *** Balloon Angioplasty for Symptomatic Intracranial Artery Stenosis(BASIS)trial is a multicentre,prospective,randomised,open-label,blinded end-point trial to investigate whether balloon angioplasty plus AMM could improve clinical outcome compared with AMM alone in patients with *** eligible in BASIS were 35–80 years old,with a recent transient ischaemic attack within the past 90 days or ischaemic stroke between 14 days and 90 days prior to enrolment due to severe atherosclerotic stenosis(70%–99%)of a major intracranial *** eligible patients were randomly assigned to receive balloon angioplasty plus AMM or AMM alone at a 1:1 *** groups will receive identical AMM,including standard dual antiplatelet therapy for 90 days followed by long-term single antiplatelet therapy,intensive risk factor management and life-style *** participants will be followed up for *** outcomes Stroke or death in the next 30 days after enrolment or after balloon angioplasty procedure of the qualifying lesion during follow-up,or any ischaemic stroke or revascularisation from the qualifying artery after 30 days but before 12 months of enrolment,is the primary *** BASIS trail is the first RCT to compare the efficacy and safety of balloon angioplasty plus AMM to AMM alone in sICAS patients,which may provide an alternative perspective for treating *** registration number NCT03703635;https://***.

关键词： balloon prospective centre

Polymeric viologen-based electron transfer mediator for improving the photoelectrochemical water splitting on Sb_(2)Se_(3) photocathode

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Fundamental Research 2024年第2期4卷 291-299页

作者： Chang Liu Fusheng Li Linqin Wang Zeju Li yilong Zhao Yingzheng Li Wenlong Li Ziqi Zhao Ke Fan Fei Li Licheng sun State Key Laboratory of Fine Chemicals Institute of Artificial PhotosynthesisDUT-KTH Joint Education and Research Centre on Molecular DevicesInstitute for Energy Science and TechnologyDalian University of TechnologyDalian 116024China Center of Artificial Photosynthesis for Solar Fuels School of ScienceWestlake UniversityHangzhou 310024China Department of Chemistry School of Engineering Sciences in ChemistryBiotechnology and HealthKTH Royal Institute of TechnologyStockholm 10044Sweden

The photogenerated charge carrier separation and transportation of inside photocathodes can greatly influence the performance of photoelectrochemical(PEC)H2 production *** TiO_(2) with p-type semiconductors to construct heterojunction structures is one of the most widely used strategies to facilitate charge separation and ***,the band position of TiO_(2) could not perfectly match with all p-type ***,taking antimony selenide(Sb_(2)Se_(3))as an example,a rational strategy was developed by introducing a viologen electron transfer mediator(ETM)containing polymeric film(poly-1,1′-dially-[4,4′-bipyridine]-1,1′-diium,denoted as PV^(2+))at the interface between Sb_(2)Se_(3) and TiO_(2) to regulate the energy band alignment,which could inhibit the recombination of photogenerated charge carriers of *** Pt as a catalyst,the constructed Sb_(2)Se_(3)/PV^(2+)/TiO_(2)/Pt photocathode showed a superior PEC hydrogen generation activity with a photocurrent density of−18.6 mA cm^(-2) vs.a reversible hydrogen electrode(RHE)and a half-cell solar-to-hydrogen efficiency(HC-STH)of 1.54%at 0.17 V ***,which was much better than that of the related Sb_(2)Se_(3)/TiO_(2)/Pt photocathode without PV^(2+)(−9.8 mA cm^(-2),0.51%at 0.10 V ***).

关键词： Viologen Electron transfer mediator Sb2Se3 photocathode Solar water splitting Hydrogen evolution reaction

展示自我性生活整体的现象学范型--论何顿的写实艺术

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中南大学学报（社会科学版） 2022年第6期28卷 171-182页

作者：晏杰雄孙艺珑中南大学文学与新闻传播学院湖南长沙410083

作为进入权威文学史著述的“新生代”作家,何顿的写实艺术既继承了现实主义文学传统,也融合了基于个人生命体验的当下性观照,提供了一个展示自我性生活整体的现象学范型,为当代文学创作提供了新经验。首先,是采用“在场式”的表达立场,... 详细信息

作为进入权威文学史著述的“新生代”作家,何顿的写实艺术既继承了现实主义文学传统,也融合了基于个人生命体验的当下性观照,提供了一个展示自我性生活整体的现象学范型,为当代文学创作提供了新经验。首先,是采用“在场式”的表达立场,直接介入事物内部,与世界原初状态相接触;其次,是使用“生活流”的结构方式,将日常生活作为主要审美对象,如实展现生活的本真面貌;最后,是践行“向下沉”的审丑美学,不避讳对丑态事物的描写,揭示生活被遮蔽的本质。借助上述写实方法,何顿构建了一个原初化的生活世界,文本和生活的界限得以被打破,展现出浓郁的地域文化特色和世俗化底色。

关键词：何顿写实艺术在场式生活流审丑生活世界

数字化时代的主体危机及个人决断——评阎真长篇小说《如何是好》

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当代作家评论 2023年第6期 151-157页

作者：晏杰雄孙艺珑中南大学人文学院

优秀的小说是民族的秘史与时代的显微镜,它通过不断补充、延伸、扩展至历史和人性深处的文字肌理,实现对当下客观世界和隐性精神世界的揭发。作为一位学者型作家,阎真在以文字忠实记录当代中国生活的同时,也满怀关切地探究当代人的精神... 详细信息

优秀的小说是民族的秘史与时代的显微镜,它通过不断补充、延伸、扩展至历史和人性深处的文字肌理,实现对当下客观世界和隐性精神世界的揭发。作为一位学者型作家,阎真在以文字忠实记录当代中国生活的同时,也满怀关切地探究当代人的精神处境,写出他们渺小的悲哀与生命的冲决。长篇小说《如何是好》讲述家境普通的女大学生许晶晶奋力拼搏却又四处碰壁的尴尬困境,挖掘时代隐疾,延续了阎真重视“精神背景”的写作路子。

关键词：阎真忠实记录数字化时代主体危机四处碰壁学者型作家精神处境精神背景

上覆软黏土层对桩-筒复合基础承载性能的影响

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哈尔滨工业大学学报 2023年第2期55卷 108-116页

作者：孙艳国许成顺杜修力豆鹏飞王丕光孙毅龙城市与工程安全减灾教育部重点实验室(北京工业大学) 北京100124 清华大学土木水利学院北京100084

中国大多数海洋场地存在上覆软弱地层,这种海床特性对海上风电场建设十分不利。为研究上覆软黏土层对新型桩-筒复合基础承载性能的影响,基于有限元软件ABAQUS,建立不同厚度的上覆软黏土层场地中桩-筒复合基础数值分析模型,分别对桩-筒... 详细信息

中国大多数海洋场地存在上覆软弱地层,这种海床特性对海上风电场建设十分不利。为研究上覆软黏土层对新型桩-筒复合基础承载性能的影响,基于有限元软件ABAQUS,建立不同厚度的上覆软黏土层场地中桩-筒复合基础数值分析模型,分别对桩-筒复合基础施加单向荷载(V、H、M)和复合荷载(H-M),研究上覆软黏土层厚度对各向极限承载力、桩-筒复合基础中各结构荷载分担比以及初始刚度k_(init)的影响。结果表明:桩-筒复合基础各向极限承载力随着上覆软黏土层厚度的增加而减小,当上覆软黏土层厚度等于筒结构入土深度(b=6 m)时,桩-筒复合基础的竖向极限承载力降低了12.86%,水平极限承载力降低了46.55%,抗弯极限承载力降低了34.86%;桩-筒复合基础的初始刚度k_(init)随着上覆软黏土层厚度的增加而减小。海上风电桩-筒复合基础的设计应充分考虑上覆软黏土层对承载特性的影响。

关键词：桩-筒复合基础海上风机上覆软黏土层降低率荷载分担比初始刚度

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Structural knowledge-driven meta-learning for task offloading in vehicular networks with integrated communications,sensing and computing

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Journal of Information and Intelligence 2024年第4期2卷 302-324页

作者： Ruijin sun Yao Wen Nan Cheng Wei Wang Rong Chai yilong Hui State Key Laboratory of ISN Xidian UniversityXi'an 710071China Chongqing Key Laboratory of Mobile Communication Technology Chongqing University of Posts and TelecommunicationsChongqing 400065China

Task offloading is a potential solution to satisfy the strict requirements of computation-intensive and latency-sensitive vehicular applications due to the limited onboard computing ***,the overwhelming upload traffic may lead to unacceptable uploading *** tackle this issue,for tasks taking environmental data as input,the data perceived by roadside units(RSU)equipped with several sensors can be directly exploited for computation,resulting in a novel task offloading paradigm with integrated communications,sensing and computing(I-CSC).With this paradigm,vehicles can select to upload their sensed data to RSUs or transmit computing instructions to RSUs during the *** optimizing the computation mode and network resources,in this paper,we investigate an I-CSC-based task offloading problem to reduce the cost caused by resource consumption while guaranteeing the latency of each *** this nonconvex problem can be handled by the alternating minimization(AM)algorithm that alternatively minimizes the divided four sub-problems,it leads to high computational complexity and local optimal *** tackle this challenge,we propose a creative structural knowledge-driven meta-learning(SKDML)method,involving both the model-based AM algorithm and neural ***,borrowing the iterative structure of the AM algorithm,also referred to as structural knowledge,the proposed SKDML adopts long short-term memory(LSTM)networkbased meta-learning to learn an adaptive optimizer for updating variables in each sub-problem,instead of the handcrafted counterpart in the AM ***,to pull out the solution from the local optimum,our proposed SKDML updates parameters in LSTM with the global loss *** results demonstrate that our method outperforms both the AM algorithm and the meta-learning without structural knowledge in terms of both the online processing time and the network performance.

关键词： Knowledge-driven meta-learning Integration of communication Sensing and computing Task offloading Vehicular networks