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Railway Engineering Science 2021年第2期29卷 152-162页

作者： Xiaozhen Li yiling tan Xiaowei Qiu Zhenhua Gong Ming Wang School of Civil Engineering Southwest Jiaotong UniversityChengdu 610031China.

The aerodynamic performance of high-speed trains passing each other was investigated on a simply supported box girder bridge,with a span of 32 m,under *** bridge and train models,modeled at a geometric scale ratio of 1:30,were used to test the aerodynamic forces of the train,with the help of a designed moving test rig in the XNJD-3 wind *** effects of wind speed,train speed,and yaw angle on the aerodynamic coefficients of the train were *** static and moving model tests were compared to demonstrate how the movement of the train influences its aerodynamic *** results show that the sheltering effect introduced by trains passing each other can cause a sudden change in force on the leeward train,which is further influenced by the wind and running *** analyses related to the effect of wind and train speeds on the aerodynamic coefficients were *** relationship between the change in aerodynamic coefficients and yaw angle was finally described by a series of proposed fitting formulas.

关键词： Aerodynamic coefficient Two trains passing each other Simply supported box girder bridge Wind tunnel

Soft Substrate Induces Endothelial Cell Inflammation and Disrupts Endothelium Integrity

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Journal of Biosciences and Medicines 2021年第2期9卷 92-102页

作者： yiling tan Xiuli Mao Huanli Wang School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China

Atherosclerosis (AS) is the main cause of death and disability all over the world. A lot of efforts have been devoted to treat AS, among which tissue engineering blood vessel materials, including artificial blood vessels, stents and vascular patches, have brought hope to ameliorate the symptoms in AS patients. However, there remains a large percentage of implantation failure due to the incompatibility of the material with the body. AS is a multi-factor related disease, and chronic inflammation is a major event that involves with its pathogenesis and development. Since previous studies suggested that the stiffness of the blood vessel might affect the inflammatory conditions, in this paper, we investigate the mechanism of how substrate stiffness could affect the inflammation response of the endothelial cells (ECs). Polyacrylamide (PA) based hydrogels at different concentrations were used as the culture substrate for ECs. The mRNA expression level of VCAM-1 and ICAM-1 was determined by qRT-PCR. EC chemotactic effect was evaluated by the number of THP-1 adhered to EC monolayer. The protein levels of IκBα and NF-κB were determined by western blotting analysis. The expression and localization of the major adherens junctions (AJs) proteins, VE-cadherin and β-catenin, were evaluated by western blotting and immunofluorescence staining. Our results showed that ECs cultured on soft substrate (1 kPa) demonstrated more chemotactic effect and the amount of the monocytes adhered to them was higher than that on harder substrate (20 kPa, p < 0.05). Moreover, NF-κB signaling pathway in ECs on 1 kPa substrate was more activated compared to those on 20 kPa substrate, with the IκBα protein expression level in the cytoplasm decreasing and NF-κB translocating more into the nuclear. In addition, the AJs of the endothelial monolayer changed with the substrate stiffness. Compared with ECs on normal substrate (20 kPa), the protein expression level of β-catenin decreased (p < 0.05), and immuno

关键词： Substrate Stiffness Endothelial Cells Inflammation Adherens Junction

Substrate Stiffness Affected the Inflammatory Response of SMCs

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Journal of Biosciences and Medicines 2021年第3期9卷 44-54页

作者： Xiuli Mao Lixuan Mao Hong Zhang yiling tan Huali Wang School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China School of Engineering Computing and Mathematics Plymouth University Plymouth UK

The pathogenesis of atherosclerosis is accompanied by chronic inflammation with changes in the stiffness of the coronary artery wall. Being the main component of the vascular media, the smooth muscle cells (SMCs) are crucial to maintain blood vessel function. SMCs are mechano-sensitive, which can rapidly adapt to the fluctuations in the microenvironment of the blood vessel, including the subtle changes of the vascular stiffness. However, how substrate stiffness influences the phenotype and inflammatory response of SMCs is not well understood. In this study, we investigated the effects of substrate stiffness on SMCs phenotype, inflammatory gene expression and the nuclear factorkappa B (NFκB) signaling pathway of vascular SMCs. From 1 kPa to 100 kPa, the SMCs cytoskeleton became more and more organized with the increase of the substrate stiffness, representing by the uniformed distribution of the stress fibers. SMCs cultured on both soft (1 kPa) and hard (100 kPa) substrate increased the expression of macrophage marker CD68 molecule (CD68) and Galectin 3 (LGALS3) and the inflammatory gene Interleukin-6 (IL-6) and Interleukin-1β (IL-1β) than those on 40 kPa substrate. Moreover, the protein expression level of phosphorylated nuclear factor kappa B inhibitor (p-IκB) was higher on either soft (1 kPa) or hard (100 kPa) substrate. In consistent, the dephosphorylated IκB showed a higher expression level on the substrate stiffness of 40 kPa. These results suggested that substrate stiffness played an important role in SMCs cell morphology, phenotype and inflammatory response by affecting NFκB signaling pathway.

关键词： Vascular Smooth Muscle Cells Substrate Stiffness Inflammatory Response NFκB

金属有机框架多孔玻璃a_(g)SALEM-2的制备

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材料研究学报 2024年第5期38卷 373-378页

作者：谭依玲李诗纯孙杰西南科技大学环境友好能源材料国家重点实验室绵阳621010 中国工程物理研究院化工材料研究所绵阳621900

选择MOF晶体SALEM-2作为制备多孔玻璃的前驱体,将其熔融淬火制备出多孔玻璃a_(g)SALEM-2。X射线衍射(XRD)、扫描电镜(SEM)和热重(TGA)等分析结果表明,SALEM-2熔融前依次经历热致非晶化、重结晶和分解。SALEM-2中的部分有机配体2-甲基咪... 详细信息

选择MOF晶体SALEM-2作为制备多孔玻璃的前驱体,将其熔融淬火制备出多孔玻璃a_(g)SALEM-2。X射线衍射(XRD)、扫描电镜(SEM)和热重(TGA)等分析结果表明,SALEM-2熔融前依次经历热致非晶化、重结晶和分解。SALEM-2中的部分有机配体2-甲基咪唑(MIm)分解,产生的缺陷使其熔点降低。在淬火过程中MIm阻碍了框架结构的重新形成,从而部分保留了液态下的孔结构,淬火速率越高液态下的多孔结构保留的越多。a_(g)SALEM-2的BET比表面积最高可达150 m^(2)/g。

关键词：无机非金属材料玻璃与非晶 MOF玻璃熔融淬火多孔玻璃 N2吸附

Nanostructured ZnO/BiVO_(4)I-scheme heterojunctions for piezocatalytic degradation of organic dyes via harvesting ultrasonic vibration energy

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 488-497页

作者： yiling Li Xiaoyao Yu Yingjie Zhou Yao Lin Ying Wu Key Laboratory of the Ministry of Education for Advanced Catalysis Materials College of Chemistry and Materials ScienceZhejiang Normal UniversityJinhua 321004China

BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step *** resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure *** 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and *** enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole ***,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active ***,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.

关键词： piezoelectric catalytic heterojunction dye degradation ultrasonic vibration

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金属氧化物半导体气敏材料抗湿性能提升策略

化学进展 2022年第8期34卷 1784-1795页

作者：谭依玲李诗纯杨希金波孙杰中国工程物理研究院化工材料研究所绵阳621900 西南科技大学环境友好能源材料国家重点实验室绵阳621010

金属氧化物半导体气体传感器是目前研究和应用最为广泛的气体传感器之一,具有高灵敏、长寿命和低成本等优点。然而,金属氧化物半导体气敏材料在湿润环境中会与水蒸气发生相互作用,导致传感器的基线电阻发生漂移,气敏性能受到显著影响,... 详细信息

金属氧化物半导体气体传感器是目前研究和应用最为广泛的气体传感器之一,具有高灵敏、长寿命和低成本等优点。然而,金属氧化物半导体气敏材料在湿润环境中会与水蒸气发生相互作用,导致传感器的基线电阻发生漂移,气敏性能受到显著影响,成为传感器应用中面临的瓶颈问题。针对该问题,研究者们从抑制水的表面吸附、水与氧的竞争吸附及调控水与吸附氧的反应三个方面开发了一些金属氧化物半导体气敏材料的抗湿性能提升策略,从而提升金属氧化物半导体气敏材料的抗湿性。本文对水蒸气的影响机理进行了分析,对三类抗湿提升策略的未来发展提出展望,有望为金属氧化物半导体气敏材料抗湿性能的提升提供解决思路与方法指导。

关键词：金属氧化物半导体气敏材料抗湿表面吸附吸附氧

风屏障对简支箱梁桥上风场分布影响的试验研究

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振动与冲击 2022年第5期41卷 287-295页

作者：邱晓为李小珍谭懿玲李星星肖军西南交通大学桥梁工程系成都610031 中交第二公路工程局有限公司西安710065 中交公路长大桥建设国家工程研究中心有限公司北京100011

为探究横风作用下风屏障对简支箱梁桥上轨道上方风场特征分布的影响机理,以高速铁路典型跨度32 m预应力混凝土简支箱梁为背景,通过几何缩尺比为1∶30的节段模型风洞试验,采用三维脉动风速仪测试了铁路桥面轨道中心上方的风场信息,并考... 详细信息

为探究横风作用下风屏障对简支箱梁桥上轨道上方风场特征分布的影响机理,以高速铁路典型跨度32 m预应力混凝土简支箱梁为背景,通过几何缩尺比为1∶30的节段模型风洞试验,采用三维脉动风速仪测试了铁路桥面轨道中心上方的风场信息,并考虑了来流风环境、轨道位置、透风率等试验因素。研究结果表明:基于最小二乘法理论对试验数据进行过原点的线性拟合分析可以更好地反映测点风速与来流风速之间关系;与裸梁桥面风场的湍流强度相比,均匀来流风速对风屏障屏蔽作用下的桥面风场湍流强度影响较大,其风速比非一致性指标与其湍流强度的变异性相关;均匀风场中桥面轨道中心部分位置的风速增加可达32.8%,而湍流风场会弱化裸梁桥面等效风场的放大效应;风屏障可以有效地降低桥面风场的平均风速,透风率30%的风屏障屏蔽作用下其迎、背风侧等效风速分别为裸梁状态下的21.6%和19.4%。

关键词：简支箱梁风屏障风速比湍流强度风洞试验

含油水砂砾天然气分离器内部流场数值模拟及优化

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天然气化工—C1化学与化工 2022年第3期47卷 147-152页

作者：谭依玲袁绍军杨佳奇四川大学化学工程学院四川成都610225 昊华气体有限公司西南分公司四川成都610225 成都西柚子科技有限公司四川成都610500

采用数值分析的方法研究了含油水砂砾天然气在卧式分离器及立式旋风分离器中的分离效率及流场分布规律,采用mixture多相流模型及dpm离散相模型考虑油气水砂砾相,k-e RNG模型考虑湍流效果。基于某种型号的立式旋风分离器实验数据,通过建... 详细信息

采用数值分析的方法研究了含油水砂砾天然气在卧式分离器及立式旋风分离器中的分离效率及流场分布规律,采用mixture多相流模型及dpm离散相模型考虑油气水砂砾相,k-e RNG模型考虑湍流效果。基于某种型号的立式旋风分离器实验数据,通过建立相应数值分析模型验证了所选用模型的有效性,验证模型所选取参数与实验数据最大误差在3.26%。在该模型基础上,对油气水砂砾在所研究分离器的内部流场及分离效率进行了仿真计算,根据计算结果对分离器的结构进行优化。计算结果显示,立式旋风分离器中天然气会在旋风分离器中心位置形成气柱,气柱的长短会影响分离效率,密度较大的油沿着旋风分离器壁面逐渐螺旋下降并分离。计算结果表明,卧式分离器中增加折流板的方式可以有效地提高卧式分离器油气水砂砾的分离效率,优化后天然气的分离效率从92.60%提高到94.50%,油的分离效率从86.70%提高到92.10%;优化后整个工艺流程中天然气的分离效率从89.33%提高到91.11%,油的分离效率从86.67%提高到92.10%,计算结果为分离器的选型及研究提供了方法指导和实践优化指导。

关键词：分离器多相流数值分析化工工艺天然气处理

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品管圈在住院病案首页信息质量中的应用分析

现代医院 2021年第4期21卷 610-612页

作者：吕梅秀张素芬谭艺灵东莞市滨海湾中心医院广东东莞523900 东莞市人民医院广东东莞523900

目的研究品管圈用于医院病案首页信息质量管理中的临床价值。方法现摘选2019年1月—6月,我院未开展品管圈管理前的1 176份住院病案首页作为A组,摘选2019年7月—12月,开展品管圈后的1 176份住院病案首页作为B组,对2组的病案首页信息质量... 详细信息

目的研究品管圈用于医院病案首页信息质量管理中的临床价值。方法现摘选2019年1月—6月,我院未开展品管圈管理前的1 176份住院病案首页作为A组,摘选2019年7月—12月,开展品管圈后的1 176份住院病案首页作为B组,对2组的病案首页信息质量进行对比研究。结果 B组病案首页信息的总体缺陷率与A组相比明显更低,P <0.05,差异有统计学意义;且B组的病案首页书写合格率与A组相比明显更高,P <0.05,差异有统计学意义。结论品管圈对住院病案首页信息质量有良好的提升作用,可有效降低病案首页整体缺陷率,提高病案书写合格率,临床应用价值较高。

关键词：品管圈住院病案首页信息质量

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住院患者基本信息缺陷分析及干预

中国病案 2017年第1期18卷 8-10页

作者：谭艺灵杜玉葵李锦秀广东省东莞市人民医院病案室东莞市523059

目的分析某医院住院患者基本信息缺陷情况,提出干预措施。方法回顾性核查某院2016年1月-2016年6月住院患者基本信息,将缺陷信息按缺陷类型及科室分布情况等进行归类总结、统计和分析。结果 2016年1月-2016年6月住院患者基本信息47 879份... 详细信息

目的分析某医院住院患者基本信息缺陷情况,提出干预措施。方法回顾性核查某院2016年1月-2016年6月住院患者基本信息,将缺陷信息按缺陷类型及科室分布情况等进行归类总结、统计和分析。结果 2016年1月-2016年6月住院患者基本信息47 879份,存在缺陷的8716份,缺陷率18.19%,其中缺陷发生率最高的是外科系统,缺陷率26.34%;妇产科系统缺陷发生率最低,为12.97%。结论规范住院患者基本信息采集登记流程及严格管理制度,强化责任意识和质量意识,加强环节质控,完善提升信息系统辅助功能,是提高患者基本信息完整性、准确性的有效干预措施。

关键词：基本信息住院患者缺陷分析措施