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饲料中不同水平的脂肪和维生素E对罗非鱼生长和抗链球菌能力的影响(一)

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饲料与畜牧（新饲料） 2011年第11期 27-32页

作者： Lim C． yildirim-aksoy m Li m．H． Welker T Klesius P Aquaculture（译自）何志刚（译校）不详湖南省水产科学研究所

试验旨在研究饲料中不同水平的脂肪和维生素E对罗非鱼生长、免疫应答和对链球菌抵抗力的影响。基础饲料(粗蛋白35%,消化能14.23mJ/kg)分别添加6%、10%和14%的混合油脂(玉米油和曼哈顿鱼油比例为1:1)和维生素E50mg/kg、100mg/kg和200mg/k... 详细信息

试验旨在研究饲料中不同水平的脂肪和维生素E对罗非鱼生长、免疫应答和对链球菌抵抗力的影响。基础饲料(粗蛋白35%,消化能14.23mJ/kg)分别添加6%、10%和14%的混合油脂(玉米油和曼哈顿鱼油比例为1:1)和维生素E50mg/kg、100mg/kg和200mg/kg。每个试验组3个重复,连续饲喂12周。罗非鱼体增重、摄食量和存活率不受饲料中脂肪和维生素E水平的影响,添加14%脂肪组罗非鱼饲料效率显著比添加6%脂肪组低,但与添加10%脂肪组无显著差异。这些变化不受饲料中维生素E水平的影响。添加14%脂肪和100mg/kg的维生素E组的罗非鱼全鱼脂肪含量显著增加。肝脏中的α-维生素E水平与饲料中维生素E的变化趋势一致,但在添加14%脂肪组显著降低。血液学指标和肝指数不受饲料中各处理组的影响。添加14%脂肪水平组罗非鱼血清蛋白显著增加,但不受饲料中维生素E水平的影响。而添加200mg/kg的维生素E后,罗非鱼溶菌酶活性不受日粮中脂肪梯度影响,但在添加200mg/kg维生素E处理组显著增加。添加10%和14%脂肪水平组罗非鱼补体活性显著降低,但维生素E添加量达到100mg/kg或200mg/kg时补体活性随之增加。饲料中脂肪和维生素E水平对罗非鱼抗链球菌能力以及抗体效价都没有影响。

关键词：脂肪维生素E 罗非鱼免疫应答抗病力

Photometric Investigation of Contact Binary DY Cet Based on TESS Data

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Research in Astronomy and Astrophysics 2022年第5期22卷 121-128页

作者： m.F.yildirim Canakkale Onsekiz mart University Astrophysics Research Center and Ulupinar Observatory17020CanakkaleTurkey Canakkale Onsekiz mart University Department of Electricity and EnergyCan Vocational School17400CanakkaleTurkey

We present a photometric analysis of the Transiting Exoplanet Survey Satellite(TESS)light curve of contact binary system DY Cet and the behavior of its orbital period *** light curve and published radial velocity data analysis was performed using the Wilson-Devinney *** a result of simultaneous analysis of the light curve with radial velocity data,the masses and radii of the system’s components were determined as m_(1)=1.55±0.02 m_(⊙),m_(2)=0.55±0.01 m_(⊙) and R_(1)=1.51±0.02 R_(⊙),R_(2)=0.95±0.02 R_(⊙),*** degree of contact(f)and mass ratio(q)of the system were determined as 23%and 0.355±0.012,*** period analysis of DY Cet was conducted for the first time in this *** was observed that the orbital period has a sinusoidal change with decreasing *** explain the orbital period change,mass transfer between components is proposed with the assumption of conservative mass,and the transfer rate was calculated to be dm/dt=1.1×10^(-7) m_(⊙)yr^(-1).A possible third component is suggested for explaining the sinusoidal change,and the mass of the unseen component was determined as 0.13 m_(⊙).The age of the DY Cet system was estimated as 3.77 Gyr.

关键词： stars eclipsing binary stars-stars fundamental parameters of stars- stars individual (DY Cet)

Calculation of the infrared frequency and the damping constant (full width at half maximum) for metal organic frameworks

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Chinese Physics B 2019年第6期28卷 324-331页

作者： m Kurt H Yurtseven A Kurt S aksoy Department of Physics Canakkale 18 Mart University17100 CanakkaleTurkey Department of Physics Middle East Technical University06531 AnkaraTurkey Lapseki ICDAS CIB mTAL High School 17100 CanakkaleTurkey

The ρ(NH2) infrared(IR) frequencies and the corresponding full width at half maximum(FWHm) values for(CH3)2 NH2 FeⅢ m Ⅱ(HCOO)6(DmFe m, m = Ni, Zn, Cu, Fe, and mg) are analyzed at various temperatures by using the experimental data from the literature. For the analysis of the IR frequencies of the ρ(NH2) mode which is associated with the structural phase transitions in those metal structures, the temperature dependence of the mode frequency is assumed as an order parameter and the IR frequencies are calculated by using the molecular field theory. Also, the temperature dependence of the IR frequencies and of the damping constant as calculated from the models of pseudospin(dynamic disorder of dimethylammonium(DmA+) cations)–phonon coupling(PS) and of the energy fluctuation(EF), is fitted to the observed data for the wavenumber and FWHm of the ρ(NH2) IR mode of the niccolites studied here. We find that the observed behavior of the IR frequencies and the FWHm of this mode can be described adequately by the models studied for the crystalline structures of interest. This method of calculating the frequencies(IR and Raman) and FWHm of modes which are responsible for the phase transitions can also be applied to some other metal organic frameworks.

关键词： infrared(IR) frequency full width at half maximum(FWHm) phase transitions ρ(NH2) mode niccolites

Group classification for path equation describing minimum drag work and symmetry reductions

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Applied mathematics and mechanics(English Edition) 2010年第7期31卷 911-916页

作者： m.PAKDEmIRLI Y.aksoy Department of mechanical Engineering Celal Bayar University

The path equation describing the minimum drag work first proposed by Pakdemirli is reconsidered （Pakdemirli, m. The drag work minimization path for a fly- ing object with altitude-dependent drag parameters. Proceedings of the Institution of mechanical Engineers, Part C, Journal of mechanical Engineering Science 223（5）, 1113- 1116 （2009））. The Lie group theory is applied to the general equation. The group classi- fication with respect to an altitude-dependent arbitrary function is presented. Using the symmetries, the group-invariant solutions are determined, and the reduction of order is performed by the canonical coordinates.

关键词： minimum drag work Lie group theory group classification

Investigation of the inhomogeneous barrier height of an Au/Bi_4Ti_3O_(12)/n-Si structure through Gaussian distribution of barrier height

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Chinese Physics B 2012年第12期21卷 538-543页

作者： m.Gken m.yildirim Department of Physics Faculty of Arts and SciencesDuzce University

A Au/Bi4Ti3O12/n-Si structure is fabricated in order to investigate its current voltage （IV） characteristics in a temperature range of 300 K-400 K. Obtained I-V data are evaluated by the thermionic emission （TE） theory. Zero-bias barrier height （Ф0） and ideality factor （n） calculated from I-V characteristics, are found to be temperature-dependent such that ФB0 increases with temperature increasing, whereas n decreases. The obtained temperature dependence of ФB0 and linearity in ФB0 versus the n plot, together with a lower barrier height and Richardson constant values obtained from the Richardson plot, indicate that the barrier height of the structure is inhomogeneous in nature. Therefore, I-V characteristics are explained on the basis of Caussian distribution of barrier height.

关键词： Bi4Ti3O12 I-V characterization temperature dependence Gaussian distribution

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

SBL-JP-0004:A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology Research 2025年第1期33卷 235-243页

作者： HASSAN m.OTIFI Department of Pathology College of MedicineKing Khalid UniversityAbha62521Saudi Arabia

Background:Gastric cancer(GC)remains a global health burden and is often characterized by heterogeneous molecular profiles and resistance to conventional *** phosphoinositide 3-kinase and PI3K and Janus kinase(JAK)signal transducer and activator of transcription(JAK-STAT)pathways play pivotal roles in GC progression,making them attractive targets for therapeutic ***:This study applied a computational and molecular dynamics simulation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD *** and SNU-5 GC cells were used for in vitro ***:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases,as evidenced by molecular docking scores and molecular dynamics *** interactions and Gibbs binding free energy estimates confirmed stable and favorable interactions with target ***-JP-0004 displayed an half-maximal inhibitory concentration(IC_(50))value of 118.9 nm against JAK2 kinase and 200.9 nm against PI3KCD ***-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells,with half-maximal growth inhibitory concentration(GI50)values of 250.8 and 516.3 nm,respectively.A significant elevation in the early phase apoptosis(28.53%in KATOIII cells and 26.85%in SNU-5 cells)and late phase apoptosis(17.37%in KATOIII cells and 10.05%in SNU-5 cells)were observed with SBL-JP-0004 treatment compared to 2.1%and 2.83%in their respective ***:The results highlight SBL-JP-0004 as a promising dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Gastric cancer(GC) Dual inhibition JAK2 PI3KCD SBL-JP-0004 molecular docking molecular dynamics simulation

mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

mechanical and Antibacterial Properties of Injection molded Polypropylene/TiO_2 Nano-Composites:Effects of Surface modification

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Journal of materials Science & Technology 2012年第8期28卷 686-692页

作者： mirigul Altan Huseyin yildirim Department of mechanical Engineering Yildiz Technical UniversityYildizIstanbul34349Turkey Department of Chemistry Yildiz Technical UniversityDavutpasaIstanbul34210Turkey

Polypropylene （PP）/titanium dioxide （TiO2） nano-composites were prepared by melt compounding with a twin screw extruder. Nanoparticles were modified prior to melt mixing with maleic anhydride grafted styreneethylene-butylene-styrene （SEBS-g-mA） and silane. The composites were injection molded and mechanical tests were applied to obtain tensile strength, elastic modulus and impact strength. Antibacterial efficiency test was applied on the injection molded composite plaques by viable cell counting technique. The results showed that the composites including SEBS-g-mA and silane coated TiO2 gave better mechanical properties than the composites without SEBS-g-mA. Antibacterial efficiency of the composites varied according to the dispersion and the concentration of the particles and it was observed that composites at low content of TiO2 showed higher antibacterial property due to the better photocatalytic activity of the particles during UV exposure.

关键词： Nano-Ti02 Polypropylene mechanical property Antibacterial property Injection molding