检索结果-南通市图书馆

Frontiers of Chemical Science and Engineering 2022年第11期16卷 1616-1622页

作者： yijian li Jianbo Hu Jiyu Cui Qingju Wang Huabin Xing Xili Cui Zhejiang Key Laboratory of Smart Biomaterials Key Laboratory of Biomass Chemical Engineering of Ministry of EducationCollege of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310027China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou 311215China

Adsorptive separation of acetylene/carbon dioxide mixtures by porous materials is an important and challenging task due to their similar sizes and physical properties.Here,remarkable acetylene/carbon dioxide separation featuring a high dynamic breakthrough capacity for acetylene(4.3 mmol·g^(–1))as well as an ultralow acetylene regeneration energy(29.5 kJ·mol^(–1))was achieved with the novel TiF_(6)^(2–)-pillared material ZU-100(TIFSIX-bpy-Ni).Construction of a pore structure with abundant TiF_(6)^(2–)anion sites and pores with appropriate sizes enabled formation of acetylene clusters through hydrogen bonds and intermolecular interactions,which afforded a high acetylene capacity(8.3 mmol·g^(–1))and high acetylene/carbon dioxide uptake ratio(1.9)at 298 K and 1 bar.Moreover,the NbO_(5)^(2–)anion-pillared material ZU-61 investigated for separation of acetylene/carbon dioxide.In addition,breakthrough experiments were also conducted to further confirm the excellent dynamic acetylene/carbon dioxide separation performance of ZU-100.

关键词： acetylene carbon dioxide separation dynamic capacity anion-pillared hybrid material

Spatial transcriptome unveils a discontinuous inflammatory pattern in proficient mismatch repair colorectal adenocarcinoma

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fundamental Research 2023年第4期3卷 640-646页

作者： Rongxin Zhang Yu Feng Wenjuan Ma Yanying Guo Mei Luo Young li Yupeng Zang Xuan Dong Shixun Lu Qiang Guo Qumiao Xu Huanyi Chen yijian li Longqi liu Ao Chen Gong Chen Xun Xu Department of Colorectal Surgery Sun Yat-sen University Cancer CentreGuangzhou 510060GuangdongChina BGI-Shenzhen Beishan Industrial ZoneShenzhen 518083China State Key Laboratory of Oncology in South China Guangzhou 510060GuangdongChina Collaborative Innovation Center of Cancer Medicine Guangzhou 510060GuangdongChina Intensive Care Unit Department Sun Yat-sen University Cancer CentreGuangzhou 510060GuangdongChina College of life Sciences University of Chinese Academy of SciencesBeijing 100049China Department of Pathology Sun Yat-sen University Cancer CentreGuangzhou 510060GuangdongChina Shenzhen Bay Laboratory Shenzhen 518000China Department of Biology University of CopenhagenCopenhagen DK-2200Denmark Guangdong Provincial Key Laboratory of Genome Read and Write Shenzhen 518120China

The preexistence of immune cells in the tumor microenvironment substantiates the efficacy of immunotherapy in cancer patients.Although the complex intratumoral immune heterogeneity has been extensively studied in single cell resolution,hi-res spatial investigations are limited.In this study,we performed a spatial transcriptome analysis of 4 colorectal adenocarcinoma specimens and 2 paired distant normal specimens to identify the molecular pattern involved in a discontinuous inflammatory response in pathologically annotated cancer regions.Based on the location of spatially varied gene expression,we unmasked the spatially-varied immune ecosystem and identified the locoregional“warmed-up”immune response in predefined“cold”tumor with substantial infiltration of immune components.This“warmed-up”immune profile was found to be associated with the in-situ copy number variance and the tissue remodeling process.Further,“warmed-up”signature genes indicated improved overall survival in CRC patients obtained from TCGA database.

关键词： Colorectal adenocarcinoma Mismatch repair Inflammation Spatial transcriptomics Tumor microenvironment

Peri-procedural myocardial injury predicts poor short-term prognosis after TAVR:A single-center retrospective analysis from China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2023年第24期136卷 3013-3015页

作者： Qi liu Kaiyu Jia Yijun Yao yijian li Tianyuan Xiong Fei Chen Yuanweixiang Ou Xi Wang Yujia liang Xi li Yong Peng Jiafu Wei Sen He Qiao li Wei Meng Guo Chen Wenxia Zhou Mingxia Zheng Xuan Zhou Yuan Feng Mao Chen Department of Cardiology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Cardiovascular Surgery West China HospitalSichuan UniversityChengduSichuan 610041China Department of Anaesthesiology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Radiology West China HospitalSichuan UniversityChengduSichuan 610041China

To the Editor:Approximately 2%of people>65 years old have aortic stenosis(AS).[1]Without intervention,AS is a rapidly progressive valvular heart disease with a 2-year mortality of 50%.[1]Since the first transcatheter aortic valve replacement(TAVR)was performed by Cribier et al[2]in 2002,TAVR has been suggested to be non-inferior in AS patients of various risk stratifications.Post-TAVR complications are essential in predicting patient survival and improving quality of life,especially with the procedure being performed in an increasing population of low-risk patients.[3]Among them,myocardial infarction(MI)is a rare but life-threatening complication usually caused by the obstruction of coronary ostia.[1]In comparison,peri-procedural myocardial injury,primarily characterized by the elevation of cardiac markers,is a relatively common complication of TAVR.Although recent studies have demonstrated promising results of cardiac markers in predicting cardiovascular adverse events,the impact of peri-procedural myocardial injury on short-term and long-term mortality has yet to be established.

关键词： TAVR mortality injury

Toxicity of silicon dioxide nanoparticles with varying sizes on the cornea and protein corona as a strategy for therapy

在线全文

学校读者我要写书评

暂无评论

Science Bulletin 2018年第14期63卷 907-916页

作者： Dayu Sun linji Gong Jing xie Xianliang Gu yijian li Qinglin Cao Qiyou li Luodan A. Zhanjun Gu Haiwei Xu Department of Physiology Third Military Medical University (Army Medical University). Chongqing 400038 China Southwest Hospital/Southwest Eye Hospital Third Military Medical University(Army Medical University)Chongqing 400038 China Key Laboratory of Visual Damage and Regeneration & Restoration of Chongqing Chongqing 400038 China Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China University of Chinese Academy of Sciences Beijing 100049 China

The human cornea is exposed directly to particulate matter(PM) in polluted air. This exposure can cause eye discomfort and corneal injury. Ultrafine PM(diameter <100 nm) is thought to be particularly harmful to health... 详细信息

The human cornea is exposed directly to particulate matter(PM) in polluted air. This exposure can cause eye discomfort and corneal injury. Ultrafine PM(diameter limited research investigating its toxicity to the eye. In this study, we evaluated toxicity differences among 30-, 40-, 100-and 150-nm silicon dioxide nanoparticles(SiO_2 NPs) on the cornea. A 24-hour in vitro exposure of primary human corneal epithelial cells(hCECs) to ultrafine(30 and 40 nm) SiO_2 NPs produced toxicity, as evidenced by cell membrane damage, reduced cell viability,increased cell death and mitochondrial dysfunction. In vivo exposure to the same nanoparticles produced observable corneal injury. These effects were more severe with ultrafine than with fine(100 and 150 nm)SiO_2 NPs. Common antioxidant compounds, e.g., glutathione, did not protect the cornea from SiO_2 NP-induced damage. However, foetal bovine serum(FBS) did significantly reduce toxicity, likely by forming a protective protein corona around the nanoparticles. This finding suggests that FBS(or its derivatives) may be a useful clinical therapy for corneal toxicity caused by ultrafine particulates.

关键词：二氧化物蛋白质角膜毒性日冕治疗尺寸硅

在线全文

学校读者我要写书评

暂无评论

球舱方位通道动力学建模及参数辨识

北京航空航天大学学报 2024年第6期50卷 2001-2008页

作者：李一健周江华张晓军中国科学院空天信息创新研究院北京100094 中国科学院大学航空宇航学院北京100049

用于天文观测的高空气球姿态控制系统是一种软联结控制系统,其控制稳定性与气球吊舱的运动特性有重要关系。使用拉格朗日方程对球舱方位通道的运动学特性进行建模,并使用基于最小递推二乘的算法对球舱方位通道模型中的扭转刚度和阻尼系... 详细信息

用于天文观测的高空气球姿态控制系统是一种软联结控制系统,其控制稳定性与气球吊舱的运动特性有重要关系。使用拉格朗日方程对球舱方位通道的运动学特性进行建模,并使用基于最小递推二乘的算法对球舱方位通道模型中的扭转刚度和阻尼系数进行离线辨识。与传统的稳定性分析方法相比,所提方法进一步揭示了系统控制稳定性与系统的关系和球舱方位控制运动特性,为高空气球吊舱姿控系统的设计及优化提供了重要参考。

关键词：高空气球方位控制拉格朗日建模递推最小二乘参数辨识

Gender differences in mortality following tanscatheter aortic valve replacement(TAVR):a single-centre retrospective analysis from China

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2023年第20期136卷 2511-2513页

作者： Qi liu Yali Wang yijian li Tianyuan Xiong Fei Chen Yuanweixiang Ou Xi Wang Yijun Yao Kaiyu Jia Yujia liang Xin Wei Xi li Yong Peng Jiafu Wei Sen He Qiao li Wei Meng Guo Chen Wenxia Zhou Mingxia Zheng Xuan Zhou Zhengang Zhao Chen Mao Feng Yuan Department of Cardiology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Cardiovascular Surgery West China HospitalSichuan UniversityChengduSichuan 610041China Department of Anaesthesiology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Radiology West China HospitalSichuan UniversityChengduSichuan 610041China

To the Editor:Transcatheter aortic valve replacement(TAVR)has become an established treatment for patients with severe aortic stenosis(AS)at all levels of surgical risk.^([1,2])With the exploration of TAVR and technological developments,TAVR is an alternative for patients with intermediate or low surgical risk.^([3])There are some studies regarding gender differences in TAVR,but there are few studies on it in Asia.^([4])However,the studies of outcomes based on gender differences in TVAR are still lacking,especially in China and other Asian countries.

关键词： TAVR aortic stenosis

有色金属矿山横切割头掘进机械残余振动控制方法

在线全文

学校读者我要写书评

暂无评论

机械设计与制造工程 2024年第5期53卷 51-55页

作者：李汞李逸健田仁聪翁德庆福州东鑫矿业技术有限公司福建福州350108 中国电建集团福建省电力勘测设计院有限公司福建福州350003 中国冶金地质总局第二地质勘查院福建福州350108

为了提高掘进机械在运行过程中的稳定性,提出有色金属矿山横切割头掘进机械残余振动控制方法。首先对横切割头的载荷展开分析,发现横切割头的横摆速度会影响掘进机械的残余振动幅度,随着横摆速度的增大,振动幅度增加;然后建立最优横摆... 详细信息

为了提高掘进机械在运行过程中的稳定性,提出有色金属矿山横切割头掘进机械残余振动控制方法。首先对横切割头的载荷展开分析,发现横切割头的横摆速度会影响掘进机械的残余振动幅度,随着横摆速度的增大,振动幅度增加;然后建立最优横摆速度模型,引入混沌烟花算法获取残余振动幅度最小时的最优横摆速度;最后将最优横摆速度作为目标速度,根据横切割头的横摆速度计算速度偏差,采用模糊PID控制算法展开横摆速度控制,使实际横摆速度达到最优,以此实现横切割头掘进机械残余振动控制。实验结果表明,所提方法的载荷分析精度高、控制效果好、控制效率高。

关键词：横切割头载荷分析残余振动控制混沌烟花算法模糊PID控制算法

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

基于DBO优化的球载吊舱自抗扰姿态控制

航天控制 2024年第3期42卷 68-74页

作者：尹通志周江华张冬辉张晓军李一健中国科学院空天信息创新研究院北京100094 中国科学院大学航空宇航学院北京100049

针对采用扭转器作为执行机构的球载吊舱姿态控制方案,利用步进电机作为动力来源,设计了基于自抗扰控制(ADRC)算法的串级控制器,利用蜣螂优化算法(DBO)对控制器中的关键参数进行了寻优,利用寻优得到的控制器相关参数,对吊舱的姿态控制进... 详细信息

针对采用扭转器作为执行机构的球载吊舱姿态控制方案,利用步进电机作为动力来源,设计了基于自抗扰控制(ADRC)算法的串级控制器,利用蜣螂优化算法(DBO)对控制器中的关键参数进行了寻优,利用寻优得到的控制器相关参数,对吊舱的姿态控制进行了仿真,并考虑了吊舱在飞行过程中抛砂对控制产生的影响。仿真结果表明,所设计的控制算法能跟踪静态与动态目标,控制精度较优,并具有一定的抗干扰能力,也证明了蜣螂优化算法的有效性。

关键词：高空气球吊舱姿态控制蜣螂算法(DBO) 自抗扰控制(ADRC) 串级控制

在线全文

学校读者我要写书评

暂无评论

紧凑型多功能单级磁阀式立体磁控变压器研究

南方电网技术 2024年第5期18卷 22-30页

作者：吴泳中李亦健邸龙尤德柱刘永浩张福增卢威周凯马光晨广东电网有限责任公司肇庆供电局广东肇庆526020 南方电网科学研究院广州510663 电网环境保护全国重点实验室武汉430072 武汉大学电气与自动化学院武汉430072

电缆的规模化使用造成电力系统中容性无功功率平衡需求增加,此外高比例新能源接入也会带来无功功率波动问题。现有无功功率补偿及无功功率发生装置占地面积较大、成本较高。通过磁控电抗器与变压器一体化结合提出了一种紧凑型多功能单... 详细信息

电缆的规模化使用造成电力系统中容性无功功率平衡需求增加,此外高比例新能源接入也会带来无功功率波动问题。现有无功功率补偿及无功功率发生装置占地面积较大、成本较高。通过磁控电抗器与变压器一体化结合提出了一种紧凑型多功能单级磁阀式立体磁控变压器,同时具备传统电力变压器升降压基础功能与灵活调节无功功率的能力,尤其适用于空间有限的城市变电站。对所述磁控变压器进行了有限元仿真,验证了其运行有效性。结果表明该磁控变压器的无功功率调节容量可以达到94.5 kvar,最大变比偏移量为0.439%,谐波含量仅有3.8%,节约占地面积20%,总体性能优异,可以很好地满足城市配电网无功功率补偿的需求。

关键词：磁控变压器磁控电抗器正交解耦无功功率补偿谐波控制

A Novel Proteogenomic Integration Strategy Expands the Breadth of Neo-Epitope Sources

在线全文

学校读者我要写书评

暂无评论

A Novel Proteogenomic Integration Strategy Expands the Bread...