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Using restored two-dimensional X-ray images to reconstruct the three-dimensional magnetopause

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Earth and Planetary Physics 2024年第1期8卷 133-154页

作者： RongCong Wang JiaQi Wang DaLin Li TianRan Sun XiaoDong peng yihong Guo National Space Science Center Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing100049China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China

Astronomical imaging technologies are basic tools for the exploration of the universe,providing basic data for the research of astronomy and space *** Soft X-ray Imager(SXI)carried by the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)aims to capture two-dimensional(2-D)images of the Earth’s magnetosheath by using soft X-ray ***,the observed 2-D images are affected by many noise factors,destroying the contained information,which is not conducive to the subsequent reconstruction of the three-dimensional(3-D)structure of the *** analysis of SXI-simulated observation images shows that such damage cannot be evaluated with traditional restoration *** makes it difficult to establish the mapping relationship between SXIsimulated observation images and target images by using mathematical *** propose an image restoration algorithm for SXIsimulated observation images that can recover large-scale structure information on the *** idea is to train a patch estimator by selecting noise–clean patch pairs with the same distribution through the Classification–Expectation Maximization algorithm to achieve the restoration estimation of the SXI-simulated observation image,whose mapping relationship with the target image is established by the patch *** Classification–Expectation Maximization algorithm is used to select multiple patch clusters with the same distribution and then train different patch estimators so as to improve the accuracy of the *** results showed that our image restoration algorithm is superior to other classical image restoration algorithms in the SXI-simulated observation image restoration task,according to the peak signal-to-noise ratio and structural *** restoration results of SXI-simulated observation images are used in the tangent fitting approach and the computed tomography approach toward magnetospheric reconstruction techniques,significantly improving

关键词： Solar wind Magnetosphere Ionosphere Link Explorer(SMILE) soft X-ray imager magnetopause image restoration

A layered multifunctional framework based on polyacrylonitrile and MOF derivatives for stable lithium metal anode

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Journal of Energy Chemistry 2024年第6期93卷 282-288,I0007页

作者： Fanfan Liu peng Zuo Jing Li pengcheng Shi Yu Shao Linwei Chen yihong Tan Tao Ma Engineering Research Center of High-frequency Soft Magnetic Materials and Ceramic Powder Materials of Anhui Province School of Chemistry and Material EngineeringChaohu UniversityHefei 238024AnhuiChina Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Pharmacy Anhui University of Chinese MedicineHefei 230012AnhuiChina School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006GuangdongChina Jiujiang DeFu Technology Co. Ltd.Jiujiang 332000JiangxiChina

Composite Li metal anodes based on three-dimensional(3D) porous frameworks have been considered as an effective material for achieving stable Li metal batteries with high energy ***,uneven Li deposition behavior still occurs at the top of 3D frameworks owing to the local accumulation of Li *** promote uniform Li deposition without top dendrite growth,herein,a layered multifunctional framework based on oxidation-treated polyacrylonitrile(OPAN) and metal-organic framework(MOF) derivatives was proposed for rationally regulating the distribution of Li ions flux,nucleation sites,and electrical *** from these merits,the OPAN/carbon nano fiber-MOF(CMOF) composite framework demonstrated a reversible Li plating/stripping behavior for 500 cycles with a stable Coulombic efficiency of around 99.0% at the current density of 2 mA/cm~***,such a Li composite anode exhibited a superior cycle lifespan of over 1300 h under a low polarized voltage of 18 mV in symmetrical *** the Li composite anode was paired with LiFePO_(4)(LFP) cathode,the obtained full cell exhibited a stable cycling over 500 ***,the COMSOL Multiphysics simulation was conducted to reveal the effects on homogeneous Li ions distribution derived from the above-mentioned OPAN/CMOF framework and electrical insulation/conduction *** electrochemical and simulated results shed light on the difficulties of designing stable and safe Li metal anode via optimizing the 3D frameworks.

关键词： Lithium metal anode Layered multifunctional framework Ions flux redistribution Electrical insulation/conduction structure Uniform Li deposition

IL2rg^(-/-)大鼠支持人RSV在体内的长期感染

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中国实验动物学报 2024年第1期32卷 17-24页

作者：熊芮吴勇杨艳伟屈哲刘甦苏王誉雅马丽颖付瑞彭宜红梁春南范昌发中国食品药品检定研究院实验动物资源研究所(国家啮齿类实验动物资源库) 北京102629 北京大学医学部基础医学院病原生物学系北京100083 中国食品药品检定研究院安全评价研究所(国家药物安全评价监测中心) 北京100176

目的为了克服已有人呼吸道合胞病毒(human respiratory syncytial virus,hRSV)动物模型的局限性,如半受纳性和感染持续时间短,本文利用TALEN基因编辑技术建立了IL2rg基因敲除(IL2rg^(-/-))的大鼠模型。方法用hRSV滴鼻感染该动物模型,观... 详细信息

目的为了克服已有人呼吸道合胞病毒(human respiratory syncytial virus,hRSV)动物模型的局限性,如半受纳性和感染持续时间短,本文利用TALEN基因编辑技术建立了IL2rg基因敲除(IL2rg^(-/-))的大鼠模型。方法用hRSV滴鼻感染该动物模型,观察感染期(0~35 d)的临床表征、体重及体温变化;记录不同时间点(滴鼻感染后第4、11、20、35天)鼻腔、气管、肺等呼吸道脏器的病毒总拷贝数;在观察终点(滴鼻感染后第35天)对感染动物的靶器官进行病理分析;观察不同时间点(滴鼻感染后第4、20、35天)外周血T、B、NK、NKT细胞的变化及不同时间点多种细胞因子的变化。结果(1)通过鼻内接种hRSV后,纯合的IL2rg基因敲除大鼠的呼吸道内能保持较高的病毒载量,鼻腔中病毒的平均峰值滴度能快速升至1×10^(10 )copies/g,至第5周时,病毒依然能维持复制,病毒载量亦可达到1×10^(7)copies/g。(2)但其鼻、气管和肺组织,无明显病变。(3)感染hRSV的IL2rg^(-/-)大鼠外周血B细胞含量有上升。(4)IL-6和MCP-1两种细胞因子都在感染前期上升,在观察终点回落。结论本研究基于TALEN技术建立了IL2rg^(-/-)大鼠模型,并发现该模型能很好地支持hRSV高水平复制和并长期感染,为抗病毒药物筛选、抗hRSV抗体体内效力评价,提供了良好的动物模型。

关键词： IL2rg-/-大鼠 TALEN基因编辑技术 NK细胞缺陷人呼吸道合胞病毒感染动物模型

New prevalence estimate of Torque Teno virus(TTV) infection in healthy population and patients with chronic viral hepatitis in Jiujiang, China

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Virologica Sinica 2015年第3期30卷 218-220页

作者： Jin peng Yueyue Fang Xuesen Zhao yihong peng Jiujiang Women's & Children's Hospital Department of Microbiology School of Basic Medical SciencePeking University

Dear Editor,Torque Teno virus(TTV)is a nonenveloped human DNA virus that was isolated from the serum of a patient with transfusion-transmitted hepatitis with unknown etiology in 1997(Nishizawa et al.,1997).TTV is the first human virus with a single-stranded circular DNA genome to be identified,and is recently classified as the Alphatorquevirus genus of the Anelloviridae family by the International Committee on Taxonomy of Viruses(ICTV)(King et al.,2011).TTV shows very high

关键词： prevalence DNA transfusion circular classified etiology stranded transmitted comparable serological

Cellular Caspase-3 Contributes to EV-A71 2Apro-Mediated Down-Regulation of IFNAR1 at the Translation Level

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Virologica Sinica 2020年第1期35卷 64-72页

作者： Bangtao Chen Yuya Wang Xinyi Pei Sanyuan Wang Hao Zhang yihong peng Department of Microbiology&Infectious Disease Center School of Basic Medical SciencesPeking University Health Science CenterBeijing 100083China

Enterovirus A71(EV-A71) is the major pathogen responsible for the severe hand, foot and mouth disease worldwide, for which few effective antiviral drugs are presently available. Interferon-a(IFN-a) has been used in antiviral therapy for decades;it has been reported that EV-A71 antagonizes the antiviral activity of IFN-a based on viral 2 Apro-mediated reduction of the interferon-alpha receptor 1(IFNAR1);however, the mechanism remains unknown. Here, we showed a significant increase in IFNAR1 protein induced by IFN-a in RD cells, whereas EV-A71 infection caused obvious downregulation of the IFNAR1 protein and blockage of IFN-a signaling. Subsequently, we observed that EV-A71 2 Apro inhibited IFNAR1 translation by cleavage of the eukaryotic initiation factor 4 GI(eIF4GI), without affecting IFNAR1 m RNA levels induced by IFN-a. The inhibition of IFNAR1 translation also occurred in puromycin-induced apoptotic cells when caspase-3 cleaved e IF4 GI. Importantly, we verified that 2 Aprocould activate cellular caspase-3, which was subsequently involved in e IF4 GI cleavage mediated by 2 Apro. Furthermore, inhibition of caspase-3 activation resulted in the partial restoration of IFNAR1 in cells transfected with 2 A or infected with EV-A71, suggesting the pivotal role of both viral 2 Aproand caspase-3 activation in the disturbance of IFN-a signaling. Collectively, we elucidate a novel mechanism by which cellular caspase-3 contributes to viral 2 Apro-mediated down-regulation of IFNAR1 at the translation level during EV-A71 infection, indicating that caspase-3 inhibition could be a potential complementary strategy to improve clinical anti-EV-A71 therapy with IFN-a.

关键词： Enterovirus A71(EV-A71) Interferon alpha receptor 1(IFNAR1) 2A protease(2Apro) Caspase-3 Eukaryotic initiation factor 4GI(eIF4GI)

Effects of Abscisic Acid on Cold Resistance in Digitaria sanguinalis(L.)Scop.

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Agricultural Biotechnology 2024年第1期13卷 15-16,19页

作者： Rongbo ZHOU yihong HU Li ZHOU Jie peng Fan XIE Chenzhong JIN Key Laboratory of Crop Pest Green Control Hunan University of HumanitiesScience and TechnologyLoudi 417000China Lianyuan Fengleyuan Agricultural Development Co. Ltd.Lianyuan 417008China

[Objectives]This study was conducted to detect the protective effect of abscisic acid on chilling injury of Digitaria sanguinalis(L.)Scop,and whether this effect is related to antioxidant enzymes and osmotic adjustment.[Methods]*** plants were sprayed with abscisic acid solution,and exposed to cold stress at 15℃for 3 d after one day and then at 5℃for 25 to 30 d in a growth *** changes of plant osmotic potential under this treatment were detected.[Results]Under low temperature stress,the osmotic potential of plants in the abscisic acid treatment and the control increased,but the osmotic potential level of the abscisic acid treatment plants was *** SOD activity of plants in the ABA treatment and the control decreased under low temperature *** low temperature stress,the activity of catalase and peroxidase in ABA-treated plants was higher than that in control plants.[Conclusions]This study provides a theoretical basis for the impact of abscisic acid on the physiological response of *** to cold injury.

关键词： Digitaria sanguinalis Abscisic acid CAT POD ROS SOD

PCIe HBA控制器芯片封装基板设计与仿真

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杭州电子科技大学学报（自然科学版） 2022年第1期42卷 1-9页

作者：楼向雄高羽彭一弘杭州电子科技大学微电子研究中心浙江杭州310018 成都锐杰微科技有限公司四川成都610200

针对PCIe HBA控制器芯片,采用倒装球栅格阵列(Flip Chip Ball Gate Array,FCBGA)封装形式,完成了PCIe4.0封装基板的设计与信号仿真,保证了16 Gb/s高速差分信号传输的信号完整性。PCIe差分信号优化前后仿真结果比较结果表明,以RX0信号为... 详细信息

针对PCIe HBA控制器芯片,采用倒装球栅格阵列(Flip Chip Ball Gate Array,FCBGA)封装形式,完成了PCIe4.0封装基板的设计与信号仿真,保证了16 Gb/s高速差分信号传输的信号完整性。PCIe差分信号优化前后仿真结果比较结果表明,以RX0信号为例,工作频率为16 GHz时,差分信号的回波损耗和插入损耗分别为-8.84 dB和-1.92 dB,分别提高了2.75 dB和1.17 dB;眼图的眼宽和眼高分别为155 mV和0.53 UI,提高了7 mV和0.01 UI,优化后的封装基板设计提升了信号的传输质量,保证了PCIe的信号完整性。

关键词：芯片封装基板 S参数眼图 PCIe 信号完整性

青金桔皮绿色合成金纳米粒子及其催化性能的研究

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中国食品添加剂 2023年第12期34卷 1-7页

作者：邵思园关桦楠段雪燕彭旑泓李明刘博哈尔滨商业大学食品工程学院哈尔滨150028

采用废弃青金桔皮提取物作为还原剂兼保护剂绿色制备金纳米粒子(AuNPs),优化其绿色制备体系,并对其催化性能进行评估。通过紫外-可见光谱、激光粒度分布仪和傅里叶变换红外光谱(FTIR)等对金纳米粒子进行表征,筛选时间、温度、搅拌速度... 详细信息

采用废弃青金桔皮提取物作为还原剂兼保护剂绿色制备金纳米粒子(AuNPs),优化其绿色制备体系,并对其催化性能进行评估。通过紫外-可见光谱、激光粒度分布仪和傅里叶变换红外光谱(FTIR)等对金纳米粒子进行表征,筛选时间、温度、搅拌速度对制备体系进行优化。结果表明,所制备AuNPs的紫外可见光谱在波长536 nm处具有特征吸收峰,激光粒度分布仪显示其粒径主要分布在2~15 nm之间,平均粒径为6.51 nm。傅里叶红外光谱证实青金桔皮提取物中的还原性物质参与AuNPs的绿色合成,并对4-硝基苯酚(4-NP)还原为对氨基苯酚(4-AP)具有较强的催化活性。最佳制备条件为,青金桔皮提取物浓度50%,反应时间15 min,反应温度30℃,搅拌速度1300 r/min。综上所述,此类型AuNPs的制备工艺操作简便,经济环保,在食品工业、环境保护、生物与医药等领域将具有广阔的应用前景与实用价值。

关键词：金纳米粒子绿色制备青金桔催化活性

基于TransUNet的机动微弱目标智能检测前跟踪算法

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航空学报 2024年第12期45卷 254-268页

作者：武星蕊彭锐晖孙殿星谭顺成张一泓韦文斌哈尔滨工程大学青岛创新发展中心青岛266000 哈尔滨工程大学信息与通信工程学院哈尔滨150001 海军航空大学信息融合研究所烟台264001

隐身技术的发展和运用给雷达目标探测带来了极大的挑战,检测前跟踪技术作为微弱目标探测的重要技术方向之一,常被用于雷达探测中,但传统的检测前跟踪算法计算量大、受目标运动模型限制,难以有效检测各种不同运动状态的机动目标。针对该... 详细信息

隐身技术的发展和运用给雷达目标探测带来了极大的挑战,检测前跟踪技术作为微弱目标探测的重要技术方向之一,常被用于雷达探测中,但传统的检测前跟踪算法计算量大、受目标运动模型限制,难以有效检测各种不同运动状态的机动目标。针对该问题,提出基于TransUNet的微弱目标智能检测前跟踪算法,算法不受任何运动模型限制,可以有效识别各种运动状态的机动目标。首先,利用目标运动轨迹的空-时相关性特征,基于TransUNet模型设计了一种适用于不同运动状态的机动微弱目标粗检测算法,实现微弱机动目标的初步检测;然后,利用初步检测结果对目标量测进行区域搜索,实现微弱机动目标点迹的回溯;最后,针对低信噪比情况下初步回溯点迹的漏检问题,利用部分成功检测点迹的辅助信息,结合最佳抛物线值函数实现目标点迹的精细检测和航迹的完整回溯。仿真试验验证了本方法能够对多种运动状态的微弱机动目标实现有效检测。

关键词：检测前跟踪微弱目标 TransUNet网络空-时相关性特征目标检测最佳抛物线值函数

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