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Reconfigurable logic and in-sensor encryption operations in an asymmetrically tunable van der Waals heterostructure

Nano Research 2024年第4期17卷 3113-3119页

作者： Fan Gong Wenjie Deng Yi Wu Fengming Liu yihao guo Zelin Che Jingjie Li Jingzhen Li Yang Chai Yongzhe Zhang Key Laboratory of Optoelectronics Technology of Education Ministry of China Faculty of Information TechnologyBeijing University of TechnologyBeijing 100124China Key Laboratory of Advanced Functional Materials Ministry of EducationFaculty of Materials and ManufacturingBeijing University of TechnologyBeijing 100124China Department of Applied Physics Hong Kong Polytechnic UniversityKowloonHong KongChina

Reconfigurable devices can be used to achieve multiple logic operation and intelligent optical sensing with low power consumption,which is promising candidates for new generation electronic and optoelectronic integrated circuits.However,the versatility is still limited and need to be extended by the device architectures design.Here,we report an asymmetrically gate two-dimensional(2D)van der Waals heterostructure with hybrid dielectric layer SiO_(2)/hexagonal boron nitride(h-BN),which enable rich function including reconfigurable logic operation and in-sensor information encryption enabled by both volatile and non-volatile optoelectrical modulation.When the partial gate is grounded,the non-volatile light assisted electrostatic doping endowed partially reconfigurable doping between n-type and p-type,which allow the switching of logic XOR and not implication(NIMP).When the global gate is grounded,additionally taking the optical signal as another input signal,logic AND and OR is realized by combined regulation of the light and localized gate voltage.Depending on the high on/off current ratio approaching 105 and reliable&switchable logic gate,in-sensor information encryption and decryption is demonstrated by manipulating the logic output.Hence,these results provide strong extension for current reconfigurable electronic and optoelectronic devices.

关键词： in-sensor encryption reconfigurable logic van der Waals heterostructure asymmetrical tunable architecture

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Method to Quantifying the Logical Node Importance for IEC 61850 Based Substation Automation Systems

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CSEE Journal of Power and Energy Systems 2023年第1期9卷 272-283页

作者： Jie Yang yihao guo Chuangxin guo Zhe Chen Shenghan Wang College of Electrical Engineering Zhejiang UniversityHangzhou 310027China Electric Power Research Institute of State Grid Zhejiang Electric Power Company Hangzhou 310014China

The problem of logical node(LN)importance quantification in an IEC 61850 based substation automation system(SAS)is investigated in this paper.First,a weighted and directed static complex network model is established by analyzing the characteristics of SAS,according to IEC 61850.Then,we propose a method,which combines topology value and information adjunction value by introducing a first-order linear feedback controller to quantify the value of LNs.On this basis,some definitions for equivalent network conversion are proposed to greatly reduce the complexity of the original network topology.Also,the absolute value and relative value are introduced to quantify LN importance from the perspective of the node’s necessity and influence,respectively.Finally,simulation results of the case study demonstrate that the proposed method is effective and provides a broader and clearer perspective for viewing the logical node importance for IEC61850 based SAS.

关键词： Absolute value complex network dynamics equivalent network IEC 61850 logical node importance quantification relative value substation automation system

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A trustless architecture of blockchain-enabled metaverse

高置信计算(英文)

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高置信计算(英文) 2023年第1期3卷 1-7页

作者： Minghui Xu yihao guo Qin Hu Zehui Xiong Dongxiao Yu Xiuzhen Cheng School Computer Science and Technology Shandong UniversityQingdao 266237China Department of Computer and Information Science Indiana University-Purdue University IndianapolisUSA Information Systems Technology and Design Pillar Singapore University of Technology and DesignSingapore

Metaverse has rekindled human beings’desire to further break space-time barriers by fusing the virtual and real worlds.However,security and privacy threats hinder us from building a utopia.A metaverse em-braces various techniques,while at the same time inheriting their pitfalls and thus exposing large attack surfaces.Blockchain,proposed in 2008,was regarded as a key building block of metaverses.it enables transparent and trusted computing environments using tamper-resistant decentralized ledgers.Currently,blockchain supports Decentralized Finance(DeFi)and Non-fungible Tokens(NFT)for metaverses.How-ever,the power of a blockchain has not been sufficiently exploited.In this article,we propose a novel trustless architecture of blockchain-enabled metaverse,aiming to provide efficient resource integration and allocation by consolidating hardware and software components.To realize our design objectives,we provide an On-Demand Trusted Computing Environment(OTCE)technique based on local trust evalua-tion.Specifically,the architecture adopts a hypergraph to represent a metaverse,in which each hyper-edge links a group of users with certain relationship.Then the trust level of each user group can be evaluated based on graph analytics techniques.Based on the trust value,each group can determine its security plan on demand,free from interference by irrelevant nodes.Besides,OTCEs enable large-scale and flexible application environments(sandboxes)while preserving a strong security guarantee.

关键词： Metaverse Blockchain Edge computing Trust

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Detection of brown adipose tissue in rats with acute cold stimulation using quantitative susceptibility mapping

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Chinese Medical Journal 2023年第17期136卷 2137-2139页

作者： Cuiling Zhu yihao guo Wenbin Si Qiaoling Zhong Yingjie Mei Yanqiu Feng Xiaodong Zhang Department of Radiology The Third Affiliated Hospital of Southern Medical University(Academy of Orthopedics Guangdong Province)GuangzhouGuangdong 510630China Department of Radiology Foshan Hospital of Traditional Chinese MedicineFoshanGuangdong 528000China School of Biomedical Engineering Southern Medical UniversityGuangzhouGuangdong 510515China Guangdong Provincial Key Laboratory of Medical Image Processing Southern Medical UniversityGuangzhouGuangdong 510515China Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology Southern Medical UniversityGuangzhouGuangdong 510515China Philips Healthcare GuangzhouGuangdong 510000China

To the Editor:Adipose tissue occurs in at least two different entities in mammals and humans:brown adipose tissue(BAT)and white adipose tissue(WAT).BAT is characterized by a unique uncoupling protein 1(UCP1)in the mitochondria that enables the uncoupling of the respiratory chain from adenosine triphosphate synthesis.Thus,energy is dissipated as heat to reduce fat accumulation.BAT is also considered a highly heterogeneous tissue with abundant oxygen,blood supply,and iron-rich mitochondria.[1,2]Activation of BAT via exposure to a cold environment is considered to be a means of reducing triglycerides to fight obesity.[3]The alterations in cells and tissues of activated BAT include increased iron content and UCP1 expression in mitochondrial,blood perfusion,and lipid utilization.[4]Therefore,accurate identification and quantitative analysis of inactive and activated BAT are of great significance for the treatment of metabolic diseases that target BAT,such as obesity.

关键词： stimulation alterations susceptibility

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When blockchain meets smart grids:A comprehensive survey

High-Confidence Computing

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High-Confidence Computing 2022年第2期2卷 41-60页

作者： yihao guo Zhiguo Wan Xiuzhen Cheng School of Computer Science and Technology Shandong UniversityQingdaoChina Zhejiang Lab HangzhouChina

Recent years have witnessed an increasing interest in the blockchain technology,and many blockchain-based applications have been developed to take advantage of its decentralization,transparency,fault tolerance,and strong security.In the field of smart grids,a plethora of proposals have emerged to utilize blockchain for aug-menting intelligent energy management,energy trading,security and privacy protection,microgrid management,and energy vehicles.Compared with traditional centralized approaches,blockchain-based solutions are able to exploit the advantages of blockchain to realize better functionality in smart grids.However,the blockchain tech-nology itself has its disadvantages in low processing throughput and weak privacy protection.Therefore,it is of paramount importance to study how to integrate blockchain with smart grids in a more effective way so that the advantages of blockchain can be maximized and its disadvantages can be avoided.This article surveys the state-of-the-art solutions aiming to integrate the emergent blockchain technology with smart grids.The goal of this survey is to discuss the necessity of applying blockchain in different components of smart grids,identify the challenges encountered by current solutions,and highlight the frameworks and techniques used to integrate blockchain with smart grids.We also present thorough comparison studies among blockchain-based solutions for smart grids from different perspectives,with the aim to provide insights on inte-grating blockchain with smart grids for different smart grid management tasks.Finally,we list the current projects and initiatives demonstrating the current effort from the practice side.Additionally,we draw attention to open problems that have not yet been tackled by existing solutions,and point out possible future research directions.

关键词： Blockchain Smart Grid Survey

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Strategy to minimize bending strain interference for flexible acoustic wave sensing platform

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npj Flexible Electronics 2022年第1期6卷 820-828页

作者： Jian Zhou Zhangbin Ji yihao guo Yanghui Liu Fengling Zhuo Yuanjin Zheng Yuandong(Alex)Gu YongQing Fu Huigao Duan College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082China School of Electrical and Electronical Engineering Nanyang Technological UniversitySingapore 639798Singapore Shanghai IndustrialμTechnology Research Institute(SITRI) 235 Chengbei RdShanghai 201800China Faculty of Engineering and Environment Northumbria UniversityNewcastle upon Tyne NE18STUnited Kingdom Greater Bay Area Institute for Innovation Hunan UniversityGuangzhou 511300China

There are great concerns for sensing using flexible acoustic wave sensors and lab-on-a-chip,as mechanical strains will dramatically change the sensing signals(e.g.,frequency)when they are bent during measurements.These strain-induced signal changes cannot be easily separated from those of real sensing signals(e.g.,humidity,ultraviolet,or gas/biological molecules).Herein,we proposed a new strategy to minimize/eliminate the effects of mechanical bending strains by optimizing off-axis angles between the direction of bending deformation and propagation of acoustic waves on curved surfaces of layered piezoelectric film/flexible glass structure.This strategy has theoretically been proved by optimization of bending designs of off-axis angles and acoustically elastic effect.Proof-of-concept for humidity and ultraviolet-light sensing using flexible SAW devices with negligible interferences are achieved within a wide range of bending strains.This work provides the best solution for achieving high-performance flexible acoustic wave sensors under deformed/bending conditions.

关键词： bending wave humidity

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Discovery of novel heteroaryl alkynes for highly potent KIT^(D816V) cells inhibition to treat gastrointestinal stromal tumors

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Acta Pharmaceutica Sinica B 2022年第10期12卷 4004-4007页

作者： Zhicheng Xie Lin Li yihao guo Mi Zhang Taiwen Chen Yongpeng Li Xin Li Xi Zhu Yu Zhang Liguang Lou Youhong Hu State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Chinese Materia Medica Nanjing University of Chinese MedicineNanjing 210023China School of Pharmaceutical Science and Technology Hangzhou Institute for Advanced StudyUCASHangzhou 310024China

To the Editor:Gastrointestinal stromal tumors(GIST)is the most popular mesenchymal tumor in the gastrointestinal tract with approximately 80%of GIST harboring gain-of-function mutations at either the extracellular region(exon 9)or the juxtamembrane domain(JMD,exon 11)of KIT,resulting in uncontrolled proliferation and resistance to apotosis1.

关键词： KIT^(D816V)cells Mutation Drug resistance Gastrointestinal stromal tumors

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A new strategy to minimize humidity influences on acoustic wave ultraviolet sensors using ZnO nanowires wrapped with hydrophobic silica nanoparticles

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Microsystems & Nanoengineering 2022年第6期8卷 73-83页

作者： yihao guo Jian Zhou Zhangbin Ji Yanghui Liu Rongtao Cao Fengling Zhuo Kaitao Tan Huigao Duan Yongqing Fu College of Mechanical and Vehicle Engineering Hunan UniversityChangshaChina Faculty of Engineering and Environment Northumbria UniversityNewcastle upon TyneUK

Surface acoustic wave(SAW)technology has been widely developed for ultraviolet(UV)detection due to its advantages of miniaturization,portability,potential to be integrated with microelectronics,and passive/wireless capabilities.To enhance UV sensitivity,nanowires(NWs),such as ZnO,are often applied to enhance SAW-based UV detection due to their highly porous and interconnected 3D network structures and good UV sensitivity.However,ZnO NWs are normally hydrophilic,and thus,changes in environmental parameters such as humidity will significantly influence the detection precision and sensitivity of SAW-based UV sensors.To solve this issue,in this work,we proposed a new strategy using ZnO NWs wrapped with hydrophobic silica nanoparticles as the effective sensing layer.Analysis of the distribution and chemical bonds of these hydrophobic silica nanoparticles showed that numerous C-F bonds(which are hydrophobic)were found on the surface of the sensitive layer,which effectively blocked the adsorption of water molecules onto the ZnO NWs.This new sensing layer design minimizes the influence of humidity on the ZnO NW-based UV sensor within the relative humidity range of 10–70%.The sensor showed a UV sensitivity of 9.53 ppm(mW/cm^(2))^(−1),with high linearity(R^(2) value of 0.99904),small hysteresis(<1.65%)and good repeatability.This work solves the long-term dilemma of ZnO NW-based sensors,which are often sensitive to humidity changes.

关键词： nanowires nanoparticles ultraviolet

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川中—川东地区侏罗系大安寨段古环境及油气地质意义

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沉积学报 2024年第3期42卷 1016-1031页

作者：郭奕浩曾德铭张芮王兴志黄董张本健谢圣阳西南石油大学地球科学与技术学院成都610500 油气藏地质及开发工程国家重点实验室·西南石油大学成都610500 中国石油西南油气田分公司成都610041

【目的】四川盆地侏罗纪大安寨期不同地区古环境特征差异较大,探讨其演化特征及地质意义将有助于加快油气勘探的步伐。【方法】利用四川盆地中部和东部侏罗系大安寨段钻井岩心和野外剖面等地质资料,结合元素地球化学分析方法,对大安寨... 详细信息

【目的】四川盆地侏罗纪大安寨期不同地区古环境特征差异较大,探讨其演化特征及地质意义将有助于加快油气勘探的步伐。【方法】利用四川盆地中部和东部侏罗系大安寨段钻井岩心和野外剖面等地质资料,结合元素地球化学分析方法,对大安寨期古气候、古氧化还原、古盐度等古环境进行恢复和对比分析。【结果】川中—川东地区大安寨段岩性可划分为页岩、介壳页岩、泥岩、粉砂质泥岩、泥质粉砂岩、介壳灰岩和泥质介壳灰岩;大安寨第三亚段沉积期气候为干燥—半干燥,水体为亚还原条件的淡水—半咸水,处于浅湖—半深湖环境;大安寨第二亚段沉积期气候为半干燥—半潮湿,降水量较多,气温较低,水体为亚还原条件的淡水,处于半深湖环境;大安寨第一亚段沉积期气候为干燥—半干燥,水体为氧化—亚还原条件的半咸水—咸水,处于滨湖—浅湖环境;RA1井与YT1井大安寨时期均具有气候干燥→潮湿→干燥、降水量少→多→少、气温高→低→高、水体还原性弱→强→弱、古盐度高→低→高的规律;大安寨第三亚段沉积期至大安寨第二亚段沉积早期,湖盆沉积中心由川东地区往川中地区迁移,大安寨第二亚段沉积晚期至大安寨第一亚段沉积期,湖盆沉积中心则由川中地区往川东地区迁移;大安寨第二亚段TOC平均值为1.70%,孔隙度平均值为4.93%,荧光显示强烈,是大安寨段页岩油的主要生油层和储集层;古环境因素对源储配置具有较大影响,较潮湿的气候、较多的降水、较低的气温、还原性的水体和较低的盐度有利于泥页岩沉积、有机质富集和孔隙发育。【结论】川中—川东地区大安寨段古环境控制泥页岩沉积和有机质富集规律,影响页岩孔隙发育程度,这一认识可为明确四川盆地页岩油有利勘探区提供理论依据。

关键词：古环境恢复沉积中心迁移源储配置大安寨段四川盆地

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Highly effective self-assembled porphyrin MOCs nanomaterials for enhanced photodynamic therapy in tumor

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Chinese Chemical Letters 2024年第5期35卷 302-306页

作者： yihao Zhang Yang Jiao Xianchao Jia Qiaojia guo Chunying Duan School of Chemistry Dalian University of TechnologyDalian 116024China State Key Laboratory of Fine Chemicals School of ChemistryDalian University of TechnologyDalian 116024China

Porphyrins and their derivatives are excellent photosensitizers in photodynamic therapy(PDT).The modification of porphyrin molecules into metal-organic cages(MOCs)is a viable strategy to improve their bioavailability.In this work,MOC C66 based on porphyrin was synthesised by a one-pot self-assembly method.The three-dimensional structure of the metal-organic cage ameliorated the aggregation and selfquenching of porphyrins and increased the molar absorption coefficient in the visible light region,which enhanced the reactive oxygen species(ROS)yield of porphyrins and effectively improved the efficiency of photodynamic therapy.ROS generation ability tests in solution confirmed the improved reactive oxygen capacity of the cage,which showed greater phototoxicity to HeLa and MCF-7 cells in vitro,suggesting a new strategy for future modifications of the simple synthesis of porphyrins as photosensitizers.

关键词： Metal-organic cage Porphyrin Photodynamic therapy Reactive oxygen species Nanoparticles

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