检索结果-南通市图书馆

Potential and policy issues for sustainable development of wind power in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Power Systems and Clean Energy 2013年第3期1卷 204-215页

作者： Zhongfu TAN H.W.NGAN Yang WU Huijuan ZHANG yihang song Chao YU School of Economics and Management North China Electric Power UniversityBeijingChina School of Economics and Management Shanghai University of Electric PowerShanghaiChina Department of Electrical Engineering The Hong Kong Polytechnic UniversityHong KongChina

This paper presents a macroscopic view on the prevailing policy and potential issues in respect of the sustainable wind power development in *** starts by analyzing the characteristics of wind power resources and pin-pointing the relationship between the regulatory policies and various economic,taxation,legal and grid integration attributes relating to the wind power *** it follows by analyzing the status quo and capabilities of the wind power manufacturing industry in China including its operational efficiency and grid integration *** economic and environmental benefits are estimated by relating to the associated costing analysis in respect of the major contributing factors such as manufacturing,operational and financial *** of the associated benefits analysis indicate that the use of the wind power generation helps to save a significant equivalent amount of standard coal consumption resulting to reduction of emission ***,the potential of wind power development in China is shown to be affirmative and the sustainable energy policy is effectively implemented in China.

关键词： Wind power Renewable energy policy Sustainable development Energy saving Emission reduction

Neutrophil-derived PAD4 induces citrullination of CKMT1 exacerbates mucosal inflammation in inflammatory bowel disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2024年第6期21卷 620-633页

作者： Shuling Wang yihang song Zhijie Wang Xin Chang Haicong Wu Ziwei Yan Jiayi Wu Zixuan He Le Kang Wenjun Hu Tian Xia Zhaoshen Li Xingxing Ren Yu Bai National Clinical Research Center for Digestive Diseases Department of GastroenterologyChanghai HospitalNaval Medical UniversityShanghai200433China National Key Laboratory of Immunology and Inflammation Naval Medical UniversityShanghai200433China Changhai Clinical Research Unit Changhai HospitalNaval Medical UniversityShanghai200433China Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai200433China Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei230027China

Peptidyl arginine deiminase 4(PAD4)plays a pivotal role in infection and inflammatory diseases by facilitating the formation of neutrophil extracellular traps(NETs).However,the substrates of PAD4 and its exact role in inflammatory bowel disease(IBD)remain *** this study,we employed single-cell RNA sequencing(scRNA-seq)and substrate citrullination mapping to decipher the role of PAD4 in intestinal inflammation associated with *** results demonstrated that PAD4 deficiency alleviated colonic inflammation and restored intestinal barrier function in a dextran sulfate sodium(DSS)-induced colitis mouse ***-seq analysis revealed significant alterations in intestinal cell populations,with reduced neutrophil numbers and changes in epithelial subsets upon PAD4 *** expression analysis highlighted pathways related to inflammation and epithelial cell ***,we found that neutrophil-derived extracellular vesicles(EVs)carrying PAD4 were secreted into intestinal epithelial cells(IECs).Within IECs,PAD4 citrullinates mitochondrial creatine kinase 1(CKMT1)at the R242 site,leading to reduced CKMT1 protein stability via the autophagy *** action compromises mitochondrial homeostasis,impairs intestinal barrier integrity,and induces IECs ***-specific depletion of CKMT1 exacerbated intestinal inflammation and apoptosis in mice with *** analysis of IBD patients revealed elevated levels of PAD4,increased CKMT1 citrullination,and decreased CKMT1 *** summary,our findings highlight the crucial role of PAD4 in IBD,where it modulates IECs plasticity via CKMT1 citrullination,suggesting that PAD4 may be a potential therapeutic target for IBD.

关键词： Peptidyl-arginine deiminase-4 Citrullination Mitochondrial creatine kinase 1 Intestinal epithelial cells Inflammatory bowel disease

Analysis of Traffic Accidents Based on the Integration Model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Electronic Research and Application 2024年第1期8卷 51-59页

作者： Yanshun Ma Yi Shi yihang song Chenxiao Wu Yuanzhi Liu The School of Civil Engineering and Transportation Northeast Forestry UniversityHarbin 150040Heilongjiang ProvinceChina

To enhance the safety of road traffic operations,this paper proposed a model based on stacking integrated learning utilizing American road traffic accident ***,the process involved data cleaning,transformation,and ***,various classification models were constructed,including logistic regression,k-nearest neighbors,gradient boosting,decision trees,AdaBoost,and extra trees *** metrics such as accuracy,precision,recall,F1 score,and Hamming loss were *** analysis,the passive-aggressive classifier model exhibited superior comprehensive indices compared to other *** on the model’s output results,an in-depth examination of the factors influencing traffic accidents was ***,measures and suggestions aimed at reducing the incidence of severe traffic accidents were *** findings served as a valuable reference for mitigating the occurrence of traffic accidents.

关键词： Stacking integrated learning Data analysis Traffic safety

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

胶原酶研究进展与应用

化工学报 2019年第9期70卷 3213-3227页

作者：宋易航王楚浩方柏山厦门大学化学化工学院福建厦门361000 厦门市合成生物学重点实验室福建厦门361000 福建省化学生物学重点实验室福建厦门361000

胶原蛋白广泛存在于有机体生命各组织,是构成生命体的基础性蛋白之一。胶原蛋白结构相对复杂、稳定性良好、不易受到普通蛋白酶的降解破坏。而基质金属蛋白酶和微生物胶原酶是为数不多能原位降解胶原蛋白的两类胶原酶,能够在生理环境下... 详细信息

胶原蛋白广泛存在于有机体生命各组织,是构成生命体的基础性蛋白之一。胶原蛋白结构相对复杂、稳定性良好、不易受到普通蛋白酶的降解破坏。而基质金属蛋白酶和微生物胶原酶是为数不多能原位降解胶原蛋白的两类胶原酶,能够在生理环境下保持较高酶活力从而发挥作用,因此受到研究者的广泛关注。首先简要介绍胶原蛋白及其水解酶,其次重点介绍基质金属蛋白酶和微生物胶原酶的发掘历程和水解机理,然后综述这两类酶的最新研究进展及其在医疗诊治、食品加工、环境保护及组织工程等多方面的应用,最后总结胶原酶及胶原蛋白研究现状、研究难点和未来研究方向。

关键词：生物工程酶蛋白质基质金属蛋白酶微生物胶原酶

Biocatalytic Buoyancy‑Driven Nanobots for Autonomous Cell Recognition and Enrichment

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2023年第12期15卷 334-348页

作者： Ziyi Guo Chenchen Zhuang yihang song Joel Yong Yi Li Zhong Guo Biao Kong John MWhitelock Joseph Wang Kang Liang School of Chemical Engineering Australian Centre for NanoMedicineThe University of New South WalesSydneyNSW 2052Australia Medical College Northwest Minzu UniversityLanzhou 730000People’s Republic of China General Intensive Care Unit Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouPeople’s Republic of China School/Hospital of Stomatology Lanzhou UniversityLanzhou 730000People’s Republic of China Department of Chemistry Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsCollaborative Innovation Center of Chemistry for Energy MaterialsFudan UniversityShanghai 200438People’s Republic of China Graduate School of Biomedical Engineering The University of New South WalesSydneyNSW 2052Australia Department of Nanoengineering University of California San DiegoLa JollaCA 92093USA

Autonomously self-propelled nanoswimmers represent the nextgeneration nano-devices for bio-and environmental ***,current nanoswimmers generate limited energy output and can only move in short distances and duration,thus are struggling to be applied in practical challenges,such as living cell ***,we describe the construction of biodegradable metal-organic framework based nanobots with chemically driven buoyancy to achieve highly efficient,long-distance,directional vertical motion to“find-and-fetch”target *** surface-functionalized with antibodies against the cell surface marker carcinoembryonic antigen are exploited to impart the nanobots with specific cell targeting capacity to recognize and separate cancer *** demonstrate that the self-propelled motility of the nanobots can sufficiently transport the recognized cells autonomously,and the separated cells can be easily collected with a customized glass column,and finally regain their full metabolic potential after the *** utilization of nanobots with easy synthetic pathway shows considerable promise in cell recognition,separation,and enrichment.

关键词： Nanobots Surface functionalization Cell recognition Cell separation Metal-organic frameworks

Recent Research Progress in Premature Ovarian Failure

在线全文

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第7期8卷 274-281页

作者： Yaping Meng Xi Xia Wenjie Jiang Minghui Hao Ziqi Fan yihang song Northwest Minzu University Medical College Lanzhou 730030Gansu ProvinceChina

Premature ovarian failure refers to ovarian function failure in women before the age of 40 years due to follicular depletion or follicular dysfunction resulting in abnormal hormone *** etiology and pathogenesis of premature ovarian failure may be related to genetic,immunological,medical,environmental,infectious,psychological and enzyme *** treatment involves Western medicine,Chinese medicine,and a combination of Chinese and Western medicine,and the treatment level includes hormone level,cellular level,surgery and psychological *** paper would like to review the progress of the etiology,pathogenesis and treatment of premature ovarian failure in recent years.

关键词： Premature ovarian failure Etiology Pathogenesis Treatment

制造业升级对中国式现代化进程的基础性作用与推动途径

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

学术研究 2022年第12期 96-106页

作者：张杰宋宜航中国人民大学中国经济发展与改革研究院、国有经济研究院北京100872 中国劳动关系学院北京100048

制造业升级是推动中国式现代化进程的基础性因素,构建具有全球领先优势的高端制造业体系在很大程度上决定着中国社会主义现代化强国建设目标的顺利实现。本文构建了全面理解制造业升级活动对一国现代化进程的持续性推动作用的理论框架,... 详细信息

制造业升级是推动中国式现代化进程的基础性因素,构建具有全球领先优势的高端制造业体系在很大程度上决定着中国社会主义现代化强国建设目标的顺利实现。本文构建了全面理解制造业升级活动对一国现代化进程的持续性推动作用的理论框架,以此归纳和分析全球代表性国家在推进现代化进程中可能面临的各种典型发展陷阱。在此基础上,从五个方面分析当前中国推动制造业体系持续性升级的重点方向,并由此指出在中国式现代化的总体框架下推动制造业体系持续性升级的具体途径和重大改革突破口。

关键词：制造业升级中国式现代化理论框架突破路径改革突破口

适应清洁能源发展和现货市场运行的容量市场机制设计

在线全文

学校读者我要写书评

暂无评论

电力系统自动化 2021年第22期45卷 174-182页

作者：尚楠张翔宋艺航张妍南方电网能源发展研究院有限责任公司广东省广州市510663

随着中国电力体制改革的不断深化与现货市场建设的全面铺开,部分省区已暴露出电力容量充裕性不足、发电资源产生大量搁浅成本等问题,亟须完善容量市场机制,健全电力市场体系,以促进机组投资和保障发电容量充裕性。文中提出了一种适应清... 详细信息

随着中国电力体制改革的不断深化与现货市场建设的全面铺开,部分省区已暴露出电力容量充裕性不足、发电资源产生大量搁浅成本等问题,亟须完善容量市场机制,健全电力市场体系,以促进机组投资和保障发电容量充裕性。文中提出了一种适应清洁能源发展且与现货市场运行相适应的容量市场机制。一方面,将现货电能量交易要素纳入考虑,调动了容量资源在固定成本和运行成本两方面的竞争力,强化了容量投建与系统运行的联系,有利于形成更加切实可行的容量投建方案;另一方面,切合"碳达峰、碳中和"目标,内嵌能源结构约束以兼容产业结构调整从而获得满足能源清洁低碳转型要求和经济性最优的容量组合。最后,通过构建双层优化模型实现计及现货市场运行的容量竞价集中出清,采用改进的IEEE 24节点等系统的算例模拟计算表明,所提机制能够在激励市场主体主动参与、适应未来清洁能源成本替代效应的同时,实现市场整体经济效率的有效改进。

关键词：容量市场现货市场能源转型双层优化

跨区域电力资源供需均衡仿真的系统动力学模型

在线全文

学校读者我要写书评

暂无评论

电网技术 2014年第11期38卷 2986-2992页

作者：宋艺航张会娟谭忠富南方电网科学研究院广东省广州市510080 电力规划设计总院北京市西城区100120 华北电力大学能源经济与环境研究所北京市昌平区102206

中国电力资源与负荷呈逆向分布,须通过跨区域调配实现电能的供需平衡。为理顺区域间能源生产、能源输送与经济发展系统之间的因果传递与反馈关系,综合考虑风电生产、煤炭价格波动、经济发展对能源价格的弹性、能源输送成本以及碳排放价... 详细信息

中国电力资源与负荷呈逆向分布,须通过跨区域调配实现电能的供需平衡。为理顺区域间能源生产、能源输送与经济发展系统之间的因果传递与反馈关系,综合考虑风电生产、煤炭价格波动、经济发展对能源价格的弹性、能源输送成本以及碳排放价格等因素,基于系统动力学模型对跨区域电力资源供需的均衡关系进行模拟仿真。仿真结果表明,煤炭的供需关系将通过价格机制影响经济发展,而风电通过缓解煤炭供应压力将在一定程度上正反馈于经济增长;此外,输电通道的建设可以提高风电的消纳能力,进而进一步促进经济发展。

关键词：电力资源跨区域供需均衡系统动力学