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骨痿Ⅰ号方治疗原发性骨质疏松症肾虚血瘀证疗效及对骨代谢和炎症指标的影响

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中国中医药信息杂志 2023年第7期30卷 157-161页

作者：严一峰丁惠宇钱冬晨朱保华(指导) 南京中医药大学第二附属医院江苏南京210017

目的观察骨痿Ⅰ号方对原发性骨质疏松症(POP)肾虚血瘀证患者的疗效及对骨代谢和炎症指标的影响。方法采用随机数字表法将60例POP肾虚血瘀证患者分为治疗组和对照组各30例。对照组口服碳酸钙D3片、骨化三醇胶囊,治疗组在对照组基础上服... 详细信息

目的观察骨痿Ⅰ号方对原发性骨质疏松症(POP)肾虚血瘀证患者的疗效及对骨代谢和炎症指标的影响。方法采用随机数字表法将60例POP肾虚血瘀证患者分为治疗组和对照组各30例。对照组口服碳酸钙D3片、骨化三醇胶囊,治疗组在对照组基础上服用骨痿Ⅰ号方,每日1剂,分早晚2次口服。2组均连续治疗3个月。评价2组临床疗效,比较2组治疗前、治疗1周及治疗1、3个月疼痛视觉模拟评分法(VAS)评分,比较2组治疗前后中医证候评分、L_(1~4)骨密度及血清抗酒石酸酸性磷酸酶-5b(TRACP-5b)、β型胶原C端肽(β-CTX)、骨钙素(BGP)、白细胞介素(IL)-6、IL-10、肿瘤坏死因子(TNF)-α水平。监测2组不良反应。结果治疗组总有效率为93.33%(28/30),对照组为80.00%(24/30),治疗组临床疗效优于对照组(P0.05)。结论骨痿Ⅰ号方可有效改善POP肾虚血瘀证患者临床症状,增加骨密度、调节骨代谢,减轻炎性反应,提高临床疗效。

关键词：原发性骨质疏松症骨痿Ⅰ号方骨代谢炎症因子

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基于p-y曲线法的风机基础侧向承载力

中国海洋平台 2020年第4期35卷 19-25页

作者：赵亮纪传鹏颜益峰乔薛峰徐胜文上海交通大学海洋工程国家重点实验室上海200240 新疆金风科技股份有限公司北京100176 中国船舶及海洋工程设计研究院上海200011

采用有限元软件Abaqus对海上风机固定式4桩基础侧向承载能力进行数值计算。使用三维有限元法和p-y曲线法分别对简单均匀桩的位移响应进行分析,验证p-y曲线法的准确性。使用p-y曲线法分析桩径为3.2m的4桩基础侧向承载力,并与桩径为8.0m... 详细信息

采用有限元软件Abaqus对海上风机固定式4桩基础侧向承载能力进行数值计算。使用三维有限元法和p-y曲线法分别对简单均匀桩的位移响应进行分析,验证p-y曲线法的准确性。使用p-y曲线法分析桩径为3.2m的4桩基础侧向承载力,并与桩径为8.0m的单桩基础侧向承载力进行对比,表明桩径为3.2m的4桩基础侧向承载力明显优于桩径为8.0m的单桩基础。所得结论为海上风机桩基础形式的选取提供参考,并为今后采用p-y曲线法对桩基础侧向承载力的快速计算提供参考。

关键词：海上风机 p-y曲线桩基础侧向承载力三维有限元分析

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149例颅脑损伤法医学鉴定分析

皖南医学院学报 2019年第5期38卷 468-470页

作者：何勇徐义民洪亮闫宜锋许亚军芜湖市公安局刑警支队物证鉴定中心安徽芜湖241000 皖南医学院法医学院安徽芜湖241002 皖南医学院人文与管理学院安徽芜湖241002

目的:探讨各类疑难颅脑损伤案件的处理方法及原则。方法:对149例疑难颅脑损伤案件实际鉴定中遇到的疑难点进行分组,讨论其鉴定方法、鉴定难点以及鉴定意见。结果:颅脑损伤鉴定的难点主要为诊断结果认定、因果关系分析、损伤后遗症认定... 详细信息

目的:探讨各类疑难颅脑损伤案件的处理方法及原则。方法:对149例疑难颅脑损伤案件实际鉴定中遇到的疑难点进行分组,讨论其鉴定方法、鉴定难点以及鉴定意见。结果:颅脑损伤鉴定的难点主要为诊断结果认定、因果关系分析、损伤后遗症认定及致伤工具和损伤机制的判断。结论:疑难颅脑损伤案件鉴定难点大,牵涉多学科知识,本研究分析意见有助于疑难颅脑损伤案件的处理。

关键词：颅脑损伤法医临床学法医精神病学因果关系

Taurine Transporter dEAAT2 is Required for Auditory Transduction in Drosophila

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Neuroscience Bulletin 2018年第6期34卷 939-950页

作者： Ying Sun yanyan Jia yifeng Guo Fangyi Chen Zhiqiang yan State Key Laboratory of Medical Neurobiology Human Phenome InstituteMinistry of Education Key Laboratory of Contemporary AnthropologyCollaborative Innovation Center of Genetics and DevelopmentDepartment of Physiology and BiophysicsSchool of Life SciencesFudan UniversityShanghai 200438China Department of Human Anatomy School of Basic Medicine SciencesSouthwest Medical UniversityLuzhou 646000China Department of Biomedical Engineering Southern University of Science and TechnologyShenzhen 518055China

Drosophila dEAAT2, a member of the excitatory amino-acid transporter(EAAT) family, has been described as mediating the high-affinity transport of taurine, which is a free amino-acid abundant in both insects and mammals. However, the role of taurine and its transporter in hearing is not clear. Here, we report that dEAAT2 is required for the larval startle response to sound stimuli. d EAAT2 was found to be enriched in the distal region of chordotonal neurons where sound transduction occurs. The Ca2+imaging and electrophysiological results showed that disrupted dEAAT2 expression significantly reduced the response of chordotonal neurons to *** importantly, expressing d EAAT2 in the chordotonal neurons rescued these mutant phenotypes. Taken together,these findings indicate a critical role for Drosophila dEAAT2 in sound transduction by chordotonal neurons.

关键词： Drosophila dEAAT2 Taurine Chordotonal neurons Sound transduction

Wettability control in electrocatalyst: A mini review

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Journal of Energy Chemistry 2022年第7期31卷 643-655,I0016页

作者： yan Liang yifeng Han Jing-sha Li Jun Wang Depei Liu Qi Fan Key Laboratory of Solar Energy Science and Technology in Jiangsu Province Southeast UniversityNanjing 210096JiangsuChina National Laboratory of Solid State Microstructures Jiangsu Key Laboratory for Nano TechnologySchool of PhysicsNanjing UniversityNanjing 210093JiangsuChina Power China Huadong Engineering Corporation Limited Hangzhou 311122ZhejiangChina Institute of Materials Science and Devices School of Materials Science and EngineeringSuzhou University of Science and TechnologySuzhou 215011JiangsuChina

Electrocatalysis, as a typical heterogeneous catalysis, generally occurs in the di-or tri-phase *** is an important property for describing the balance of a gas-liquid-solid system. Therefore,the wettability of reaction interface, especially hydrophilicity/hydrophobicity, plays an important role in the adsorption/desorption process of gas bubbles on the surface of the solid electrode. Herein, we present a comprehensive review of the wettability control of the electrode materials applied in electrocatalysis reactions, including hydrogen evolution reaction(HER), oxygen evolution reaction(OER), oxygen reduction reaction(ORR) and carbon dioxide reduction reaction(CO_(2) RR). Firstly, the basic theories of wettability as well as the impact on electrocatalysis were introduced in this review. Secondly, the overview of modifying methods of the wettability from electrocatalyst microstructure(structural modification, surface coating, introducing hydrophilic groups) and system design(electrode, device) were suggested. At last, the deficiencies and problems in the application of wettability control are discussed,and deeper and broader application prospects are proposed.

关键词： Electrocatalysis Reaction interfaces Wettability Gas evolution reactions Gas consumption reactions

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基于液体阻尼器的风机塔架减振特性

中国海洋平台 2023年第1期38卷 9-14,56页

作者：翁瑜邢赢颜益峰张志弘徐胜文上海交通大学海洋工程国家重点实验室上海200240 新疆金风科技股份有限公司北京100176

建立调频液体阻尼器(Tuned Liquid Damper,TLD)数值计算模型,利用OpenFOAM二相流动网格方法进行求解,并基于试验数据验证计算方法的有效性。分析TLD减振力与固有频率和激励频率的关系。建立Simapck与OpenFOAM耦合求解方法,对TLD在风机... 详细信息

建立调频液体阻尼器(Tuned Liquid Damper,TLD)数值计算模型,利用OpenFOAM二相流动网格方法进行求解,并基于试验数据验证计算方法的有效性。分析TLD减振力与固有频率和激励频率的关系。建立Simapck与OpenFOAM耦合求解方法,对TLD在风机塔架上的布置数量、布置位置和固有频率对风机塔架减振效果的影响进行研究。计算结果表明,当TLD的固有频率等于塔架一阶振动频率且TLD布置在塔架顶端时,TLD的减振效果更好。

关键词：调频液体阻尼器风机塔架结构减振流固耦合动力响应

Zooplankton community size-structure change and mesh size selection under the thermal stress caused by a power plant in a semi-enclosed bay

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Acta Oceanologica Sinica 2020年第8期39卷 62-70页

作者： Qianwen Shao yifeng Zhu Meixia Dai Xia Lin Chengxu Zhou Xiaojun yan Key Laboratory of Applied Marine Biotechnology School of Marine ScienceNingbo UniversityNingbo 315832China Ningbo Institute of Oceanography Ningbo 315832China

Zooplankton samples were collected using 505, 160 and 77 μm mesh nets around a power plant during four seasons in 2011. We measured total length of zooplankton and divided zooplankton into seven size classes in order to explore how zooplankton community size-structure might be altered by thermal discharge from power plant. The total length of zooplankton varied from 93.7 to 40 074.7 μm. The spatial distribution of mesozooplankton(200-2 000 μm) populations were rarely affected by thermal discharge, while macro-(2 000-10 000 μm)and megalo-zooplankton(>10 000 μm) had an obvious tendency to migrate away from the outfall of power ***, zooplankton community tended to become smaller and biodiversity reduced close to power ***, we compared the zooplankton communities in three different mesh size nets. Species richness,abundance, evenness index and Shannon-Wiener diversity index of the 505 μm mesh size were significantly lower than those recorded from the 160 and 77 μm mesh size. Average zooplankton abundance was highest in the 77 μm mesh net((27 690.0±1 633.7) ind./m^3), followed by 160 μm mesh net((9 531.1±1 079.5) ind./m^3), and lowest in 505 μm mesh net((494.4±104.7) ind./m^3). The ANOSIM and SIMPER tests confirmed that these differences were mainly due to small zooplankton and early developmental stages of zooplankton. It is the first time to use the 77 μm mesh net to sample zooplankton in such an environment. The 77 μm mesh net had the overwhelming abundance of the copepod genus Oithona, as an order of magnitude greater than recorded for 160 μm mesh net and 100% loss through the 505 μm mesh net. These results indicate that the use of a small or even multiple sampling net is necessary to accurately quantify entire zooplankton community around coastal power plant.

关键词： zooplankton coastal power plant temperature elevation size class community structure mesh size selection

Observation of an upward lightning flash with 21 upward positive leaders initiated from different wind turbines in wind farm

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High Voltage 2024年第1期9卷 163-171页

作者： Li Cai yifeng Ke Wenchao Fan Ruisheng yan Mi Zhou Jianguo Wang Yadong Fan Engineering Research Center of Ministry of Education for Lightning Protection and Grounding Technology School of Electrical Engineering and AutomationWuhan UniversityWuhanChina

As the wind turbine height increases,the probability of multiple upward leaders flashes within the wind farm *** this study,an upward lightning flash containing 21 upward positive leaders(UPLs)initiated from different wind turbines in Zhangbei Wind Farm was *** average speed of the UPLs was 1.2×10^(5) m/s,which mostly decreased to zero before reaching the cloud *** four UPLs developed to cloud height,with prolonged periods of bright light on three of them and with a minimum duration of 126 ms.A total of nine return strokes occurred on the other two dissipated leader channels,and the numbers of strokes on the two channels was six and three,*** average interstroke interval for the return strokes was 10.5 *** of these nine return strokes had peak currents smaller than 10 *** high-speed video frames confirmed that competition does exist between the UPLs,and the range of shielding effects increases as the height of the ULs *** effect of fan rotation on the initiation of upward leaders and the shielding effect between the wind turbines and upward leaders are discussed.

关键词： flash return initiated

Breeding strategy of Acrossocheilus fasciatus in the Puxi Stream of the Huangshan Mountain

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Current Zoology 2009年第5期55卷 350-356页

作者： Yunzhi yan Lili GUO Xiuying XIANG Yilong XI yifeng CHEN College of Life Sciences Anhui Normal University Provincial Key Laboratory of Biotic Environment and Ecological Safety in Anhui Wuhu 241000 Anhui China Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China

Breeding strategies of Acrossocheilus fasciatus were studied from 592 specimens collected monthly during May 2007 and April 2008 in the Puxi Stream of the Huangshan Mountain. Sex ratio of the studied population was 0.90 ： 1 （ ♀ ： ♂ ）, not significantly different from 1 ： 1. Both sexes reached their first sexual maturity at age 2 （the second calendar year of their birth）. Fifty percent of females and males reached maturity at a total length of 69.75 mm and 69.36 mm respectively, and the minimum total length was 61.54 mm and 58.96 mm, respectively. Based on the monthly changes in gonado-somatic index and egg- development process, the breeding season of the population was from May to August, with one obvious interval （in June） occurring in the breeding activity for the females. The nonsynchronous development of oocytes observed in mature ovaries indicated that A. fasciatus is a batch spawner. Absolute fecundity of A. fasciatus ranged from 308 to 2002 eggs with a mean of 857 eggs, increased significantly with total length, and was significantly different among three age groups. Relative fecundity ranged from 38.63 to 71.70 egg/g with a mean of 53.29 egg/g, and was not significantly different among the three age groups. It was suggested that these reproductive characteristics were adaptive strategies for A. fasciatus to acclimatize to lotic water where environmental factors were unstable but predictable [ Current Zoology 55 （5）： 350 - 356, 2009].

关键词： Acrossocheilus fasciatus Breeding strategy Fecundity Sexual maturity Spawning season