检索结果-南通市图书馆

Understanding of the Growth Mechanisms of Hierarchical Biomineral Structures

在线全文

学校读者我要写书评

暂无评论

Understanding of the Growth Mechanisms of Hierarchical Biomi...

Effects of gallium surfactant on AlN thin films by microwave plasma chemical vapor deposition

第十六届全国晶体生长与材料学术会议

作者： Guobin Ma yifei xu Xiyan Wang Mu Wang Xiang Yang Liu National Laboratory of Solid State Microstructures and School of PhysicsNanjing University Department of Physics Faculty of ScienceNational University of Singapore2 Science Drive 3Singapore 117542

Ordered hierarchical structures based on one-or two-dimensional nanocrystals have significant potential applications in nano lasers,solar cells,catalysis,drug delivery,and self-cleaning,*** represents an efficient bottom-up strategy to fabricate the hierarchical *** systems provide numerous examples of well-organized inorganic materials that directly develop into

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Semiconductors 2024年第9期45卷 53-60页

作者： Lu Wang xulei Qin Li Zhang Kun xu Feng Yang Shaoqian Lu yifei Li Bosen Liu Guohao Yu Zhongming Zeng Baoshun Zhang School of Physics Changchun University of Science and TechnologyChangchun 130013China Nanofabrication Facility Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China

In this work, AlN films were grown using gallium (Ga) as surfactant on 4° off-axis 4H-SiC substrates via microwave plasma chemical vapor deposition (MPCVD). We have found that AlN growth rate can be greatly improved due to the catalytic effect of trimethyl-gallium (TMGa), but AlN crystal structure and composition are not affected. When the proportion of TMGa in gas phase was low, crystal quality of AlN can be improved and three-dimensional growth mode of AlN was enhanced with the increase of Ga source. When the proportion of TMGa in gas phase was high, two-dimensional growth mode of AlN was presented, with the increase of Ga source results in the deterioration of AlN crystal quality. Finally, employing a two-step growth approach, involving the initial growth of Ga-free AlN nucleation layer followed by Ga-assisted AlN growth, high quality of AlN film with flat surface was obtained and the full width at half maximum (FWHM) values of 415 nm AlN (002) and (102) planes were 465 and 597 arcsec.

关键词： AlN thin film MPCVD gallium surfactant nucleation layer laser

在线全文

学校读者我要写书评

暂无评论

唐诗在西班牙语世界的经典化路径探析

中国翻译 2019年第2期40卷 61-67,191-192页

作者：许一飞上海外语教育出版社

唐诗是中国传统文学和文化所孕育和建构的不朽经典。19世纪以来,唐诗在西班牙语世界被译介和走向经典化。本文以西译唐诗的翻译出版为例,可试图讨论其在西班牙语国家的经典化历程,探寻汉语经典在西班牙语世界传播的受制因素并提岀一些... 详细信息

唐诗是中国传统文学和文化所孕育和建构的不朽经典。19世纪以来,唐诗在西班牙语世界被译介和走向经典化。本文以西译唐诗的翻译出版为例,可试图讨论其在西班牙语国家的经典化历程,探寻汉语经典在西班牙语世界传播的受制因素并提岀一些应对措施。

关键词：唐诗西班牙语世界经典化

Clinical and molecular significance of homologous recombination deficiency positive non-small cell lung cancer in Chinese population:An integrated genomic and transcriptional analysis

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer Research 2024年第3期36卷 282-297页

作者： yifei Wang Yidan Ma Lei He Jun Du Xiaoguang Li Peng Jiao Xiaonan Wu Xiaomao xu Wei Zhou Li Yang Jing Di Changbin Zhu Liming xu Tianlin Sun Lin Li Dongge Liu Zheng Wang Department of Pathology Department of Minimally Invasive Tumor Therapies Center Department of Thoracic Surgery Department of Oncology Department of Respiratory and Critical Care Medicine Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical SciencesBeijing 100730China Amoy Diagnostics Co. Ltd.Xiamen 361027China

Objective:The clinical significance of homologous recombination deficiency(HRD)in breast cancer,ovarian cancer,and prostate cancer has been established,but the value of HRD in non-small cell lung cancer(NSCLC)has not been fully *** study aimed to systematically analyze the HRD status of untreated NSCLC and its relationship with patient prognosis to further guide clinical ***:A total of 355 treatment-naïve NSCLC patients were retrospectively *** status was assessed using the AmoyDx Genomic Scar Score(GSS),with a score of≥50 considered ***,transcriptomic,tumor microenvironmental characteristics and prognosis between HRD-positive and HRDnegative patients were ***:Of the patients,25.1%(89/355)were *** to HRD-negative patients,HRDpositive patients had more somatic pathogenic homologous recombination repair(HRR)mutations,higher tumor mutation burden(TMB)(P<0.001),and fewer driver gene mutations(P<0.001).Furthermore,HRD-positive NSCLC had more amplifications in PI3K pathway and cell cycle genes,MET and MYC in epidermal growth factor receptor(EGFR)/anaplastic lymphoma kinase(ALK)mutant NSCLC,and more PIK3CA and AURKA in EGFR/ALK wild-type ***-positive NSCLC displayed higher tumor proliferation and immunosuppression ***-negative NSCLC showed activated signatures of major histocompatibility complex(MHC)-II,interferon(IFN)-γand effector memory CD8+T ***-positive patients had a worse prognosis and shorter progressionfree survival(PFS)to targeted therapy(first-and third-generation EGFR-TKIs)(P=0.042).Additionally,HRDpositive,EGFR/ALK wild-type patients showed a numerically lower response to platinum-free immunotherapy ***:Unique genomic and transcriptional characteristics were found in HRD-positive *** prognosis and poor response to EGFR-TKIs and immunotherapy were observed in HRD-positive *** study highlights potential actionable alterations in HRD

关键词： Non-small cell lung cancer homologous recombination deficiency genetic alterations transcriptional analysis tumor microenvironment prognosis

互变参数双混沌调制SPWM波生成原理及实现方法

在线全文

学校读者我要写书评

暂无评论

中国电机工程学报 2014年第30期34卷 5335-5342页

作者：朱立岗沈传文朱少平徐益飞西安交通大学电气工程学院陕西省西安市710049

利用混沌序列对三角波进行混沌扩频,进而实现混沌脉宽调制(pulse width modulation,PWM),可以达到降低正弦脉宽调制波(sinusoidal pulse width modulation,SPWM)谐波峰值、减少机械谐振等目的。针对传统SPWM波混沌调制在实现时混沌序列... 详细信息

利用混沌序列对三角波进行混沌扩频,进而实现混沌脉宽调制(pulse width modulation,PWM),可以达到降低正弦脉宽调制波(sinusoidal pulse width modulation,SPWM)谐波峰值、减少机械谐振等目的。针对传统SPWM波混沌调制在实现时混沌序列很快进入周期以及运算量大的问题,该文提出一种由传统Logistic混沌映射和Tent混沌映射相结合的改进的互变参数双混沌序列映射,并给出对应的SPWM波生成方法。与传统混沌序列生成方法相比,该方法具有较低的运算资源消耗,较快的运算速度和较好的混沌性,且混沌序列周期明显增加。接着给出基于现场可编辑逻辑门阵列(field-programmable gate array,FPGA)的硬件实现方法,并将该方法生成的SPWM波与其他调制方法生成的SPWM波进行对比分析。结果表明,该算法实现简单,占用资源少,并可明显降低谐波峰值。

关键词：混沌正弦脉宽调制波混沌序列周期性双混沌映射基于现场可编辑逻辑门阵列

在线全文

学校读者我要写书评

暂无评论

悬挂式卷管灌溉机的设计与研制

农业工程学报 2000年第3期16卷 32-34页

作者：严海军许一飞中国农业大学

作为农村保有量最多的小四轮拖拉机的一种配套灌溉机具 ,从结构参数的设计出发 ,提出了悬挂式卷管灌溉机的卷盘结构、动力系统、灌水车及所匹配水泵参数的确定方法。

关键词：灌水车水泵参数悬持式卷管灌溉机设计研制

在线全文

学校读者我要写书评

暂无评论

社会治理场域结构及制度执行

河南社会科学 2023年第12期31卷 88-95页

作者：许一飞黑龙江省中国特色社会主义理论体系研究中心黑龙江哈尔滨150080

社会治理场域在横向上可分为空间位置、主体关系、运行制度三个变量,在纵向上可分为国家、地方、基层三个层次。场域的产生是社会结构与功能高度分化的结果,社会治理是存在于一定场域中的人的实践。社会治理制度是社会治理场域的内生变... 详细信息

社会治理场域在横向上可分为空间位置、主体关系、运行制度三个变量,在纵向上可分为国家、地方、基层三个层次。场域的产生是社会结构与功能高度分化的结果,社会治理是存在于一定场域中的人的实践。社会治理制度是社会治理场域的内生变量,社会治理各主体在制度执行中具有不同的地位和作用。制度的生命力在于执行,社会治理场域中制度效能的发挥,必须处理好空间层次的关系和主体关系的矛盾。

关键词：社会治理场域结构制度内生性制度执行

在线全文

学校读者我要写书评

暂无评论

38MnVS非调质钢活塞锻后控制冷却工艺

锻压技术 2022年第1期47卷 180-184,202页

作者：刘江徐皓杨德行徐逸非重庆工程职业技术学院智能制造与交通学院重庆402246 重庆大学材料科学与工程学院重庆400044

对38MnVS非调质钢活塞进行锻后冷却处理并探讨了不同冷却工艺对非调质钢活塞的影响规律。首先,分析了不同冷却速率对非调质钢活塞的组织性能和力学性能的影响,可知,在冷却速率为50~90℃·min^(-1)下,非调质钢析出珠光体及铁素体时各方... 详细信息

对38MnVS非调质钢活塞进行锻后冷却处理并探讨了不同冷却工艺对非调质钢活塞的影响规律。首先,分析了不同冷却速率对非调质钢活塞的组织性能和力学性能的影响,可知,在冷却速率为50~90℃·min^(-1)下,非调质钢析出珠光体及铁素体时各方面的性能最优。然后,利用分选装置对非调质钢活塞锻件进行预选,挑选出达到合格锻造温度的活塞,并在4种不同的冷却工艺下进行冷却处理。冷却过程中,锻件首先进入冷却速率为50~90℃·min^(-1)的第1冷却装置,冷却至740~760℃;之后通过输送单元使活塞进入冷却速率为30~50℃·min^(-1)的第2冷却装置,冷却至290~310℃。工艺验证结果表明,这一冷却系统能够很好地满足使用方对活塞合格率的要求,得到的活塞锻件的性能稳定、品质优良。

关键词：非调质钢活塞冷却工艺冷却速率分选装置

Bioactive materials from berberine-treated human bone marrow mesenchymal stem cells promote alveolar bone regeneration by regulating macrophage polarization

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2024年第5期67卷 1010-1026页

作者： Ziyue Qin Yanxing Han yifei Du Yixuan Zhang Yifeng Bian Ruyu Wang Haoran Wang Fanyi Guo Hua Yuan Yongchu Pan Jianliang Jin Qigang Zhou Yuli Wang Feng Han Yan xu Jiandong Jiang Department of Oral and Maxillofacial Surgery The Affiliated Stomatological Hospital of Nanjing Medical UniversityNanjing 210029China Jiangsu Province Key Laboratory of Oral Diseases Nanjing Medical UniversityNanjing 210029China Jiangsu Province Engineering Research Center of Stomatological Translational Medicine Nanjing 210029China State Key Laboratoryof BioactiveSubstances andFunction of Natural Medicine Instituteof Materia MedicaChinese Academyof MedicalSciencesandPeking Union MedicalCollegeBeijing100050China Gusu school Nanjing medical universitySuzhou 215002China Key Laboratory of Cardiovascular&Cerebrovascular Medicine Drug Target and Drug Discovery CenterSchool of PharmacyNanjing Medical UniversityNanjing 211166 China Department of Orthodontics The Affiliated Stomatological Hospital of Nanjing Medical UniversityNanjing 210029China Department of Human Anatomy Research Centre for Bone and Stem CellsKey Laboratory for Aging&DiseaseThe State Key Laboratory of Reproductive MedicineNanjing Medical UniversityNanjing 211166China Department of Clinical Pharmacology School of PharmacyNanjing Medical UniversityNanjing Jiangsu211166China Department of Periodontology The Affiliated Stomatological Hospital of Nanjing Medical UniversityNanjing 210029China Department of Virology Institute of Medicinal BiotechnologyChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China

Alveolar bone regeneration has been strongly linked to macrophage polarization.M1 macrophages aggravate alveolar bone loss,whereas M2 macrophages reverse this ***(BBR),a natural alkaloid isolated and refined from Chinese medicinal plants,has shown therapeutic effects in treating metabolic *** this study,we first discovered that culture supernatant(CS)collected from BBR-treated human bone marrow mesenchymal stem cells(HBMSCs)ameliorated periodontal alveolar bone *** from the BBR-treated HBMSCs contained bioactive materials that suppressed the M1 polarization and induced the M2 polarization of macrophages in vivo and in *** clarify the underlying mechanism,the bioactive materials were applied to different animal *** discovered macrophage colony-stimulating factor(M-CSF),which regulates macrophage polarization and promotes bone formation,a key macromolecule in the *** of pure M-CSF attenuated experimental periodontal alveolar bone loss in ***-stimulating factor 1 receptor(CSF1R)inhibitor or anti-human M-CSF(M-CSF neutralizing antibody,Nab)abolished the therapeutic effects of the CS of BBR-treated ***,AKT phosphorylation in macrophages was activated by the CS,and the AKT activator reversed the negative effect of the CSF1R inhibitor or *** results suggest that the CS of BBR-treated HBMSCs modulates macrophage polarization via the M-CSF/AKT *** studies also showed that CS of BBR-treated HBMSCs accelerated bone formation and M2 polarization in rat teeth extraction ***,our findings established an essential role of BBR-treated HBMSCs CS and this might be the first report to show that the products of BBR-treated HBMSCs have active effects on alveolar bone regeneration.

关键词： berberine human bone marrow mesenchymal stem cells alveolar bone regeneration macrophage colony-stimulating factor AKT phosphorylation