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New perspectives on the genetic structure of dotted gizzard shad(Konosirus punctatus)based on RAD-seq

Marine Life Science & Technology 2024年第1期6卷 50-67页

作者： Ying Peng yifan liu Jiasheng Li Kun Zhang Xun Jin Sixu Zheng Yunpeng Wang Zhenming Lu Liqin liu Li Gong Bingjian liu National Engineering Laboratory of Marine Germplasm Resources Exploration and Utilization Zhejiang Ocean UniversityZhoushan 316022China National Engineering Research Center for Facilitated Marine Aquaculture Marine Science and Technology CollegeZhejiang Ocean UniversityZhoushan 316022China

To maintain,develop and rationally utilize marine organisms,understanding their genetic structure and habitat adaptation pattern is *** punctatus,which is a commercial fish species inhabiting the Indo-west Pacific Ocean,has shown an obvious annual global capture and aquaculture production decline due to climate changes and human *** the present study,restriction-site associated DNA sequencing(RAD-seq)was used to describe its genome-wide single nucleotide polymorphisms panel(SNPs).Among 146 individuals collected at nine locations scattered in China,Korea and Japan,a set of 632,090 SNPs were *** genetic analysis showed that *** individuals were divided into two significant genetic ***,potential genetic differentiation between northern and southern population of *** was *** results indicated that gene flow existed among sampling locations of ***,especially from southern Japan to ***,candidate genes associated with habitat adaptations of *** were identified,which are involved in diverse physiological processes of *** including growth and development(e.g.,KIDINS220,PAN3),substance metabolism(e.g.,PGM5)and immune response(e.g.,VAV3,CCT7,HSPA12B).Our findings may aid in understanding the possible mechanisms for the population genetic structure and local adaptation of ***,which is beneficial to establish the management and conservation units of ***,guiding the rational use of resources,with reference significance for a profound understanding of the adaptative mechanisms of other marine organisms to the environment.

关键词： Population structure Konosirus punctatus SNP RAD-seq Local adaptation

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Straw return decreases polycyclic aromatic hydrocarbon (PAH) accumulation in winter wheat and human health risk by enhancing PAH dissipation in rhizosphere soil

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Pedosphere 2024年第4期34卷 699-708页

作者： Jun CAI He ZHANG Xiangyao WU yifan liu Yunmei WU Jinfeng WANG Chuangye ZHANG Benhua SUN Fuyong WU College of Natural Resources and Environment Northwest A&F UniversityYangling 712100China Key Laboratory of Plant Nutrition and the Agri-environment in Northwest China Ministry of AgricultureYangling 712100China

Straw return in situ,a common agronomic measure in China,has been widely used not only to increase crop yields and improve soil nutrients but also to remove polycyclic aromatic hydrocarbons(PAHs)from agricultural ***,the safety risks of food crops(i.e.,human health risk of wheat grains)grown in PAHs-contaminated agricultural soils amended with crop straw remain uncertain.A pot experiment was conducted in a PAHs-contaminated agricultural soil cultivated with winter wheat under different ratios of corn straw addition(0%(control,CK),1%,2.5%,and 5%,weight/weight).Results showed that corn straw addition significantly(P<0.05)decreased PAH concentrations in rhizosphere soil,roots,straws,and grains by 48.32%–50.01%,11.85%–42.67%,9.78%–28.03%,and 14.16%–31.67%,respectively,compared with CK,whereas the transfer factors of PAHs from roots to straws were significantly(P<0.05)increased.A correlation heatmap showed that PAH concentrations in roots,straws,and grains were positively(P<0.01)correlated with those in rhizosphere *** indicated that corn straw decreased PAH accumulation in winter wheat due to the increase of PAH dissipation in the rhizosphere soil,although it enhanced PAH transfer in winter *** incremental lifetime cancer risk(ILCR)model indicated that corn straw significantly(P<0.05)decreased the human health risk of winter wheat grains by 29.73%–45.05%.Overall,corn straw apparently reduced PAH accumulation in winter wheat,ecological risk,and human health risk via enhancing PAH dissipation in the rhizosphere *** findings provide an important scientific basis and theoretical guidance for agricultural safety production.

关键词： corn straw addition ecological risk food crops incremental lifetime cancer risk transfer factor

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Nitrogen and fluorine co-doped graphene for ultra-stable lithium metal anodes

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Nano Research 2024年第8期17卷 7212-7220页

作者： Pan Li yifan liu Xujian Bao Jinghao Xie Zhao Li Hongcheng Li Qiang Ren Xiaomiao Feng Yue Hu Yanwen Ma State Key Laboratory for Organic Electronics and Information Displays(KLOEID)and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000China

The heteroatom doping strategies have been utilized to effectively improve the performance of the carbon-based hosts,such as graphene,for lithium(Li)metal in high energy density lithium metal ***,solely doped graphene hosts often need the assistance of other materials with either better lithiophilicity or electronic conductance to achieve smooth and efficient deposition of Li,which adds extra weight or ***,graphene co-doped by nitrogen and fluorine(NFG)is employed as a stable host for Li,where the N-doping provides lithiophilicity and electronic conductivity lacked by F-doping and the F-doping facilitates fast formation of solid electrolyte interphase(SEI)retarded by *** well regulation of Li plating/stripping and SEI formation is verified by quickly stabilized and small-magnitude voltage hysteresis,which stands out in Li hosts based on doped graphene and leads to excellent long-term cycling performance of NFG based electrodes.A voltage hysteresis of 20 mV is observed for more than 850 h in the symmetrical *** remarkable efficiency of lithium usage is confirmed by the highcapacity retention of a full cell paired with LiFePO_(4)(LFP),which exceeds 70%after 500 *** work presents an innovative perspective on the control of Li plating/stripping by simultaneously introducing two kinds of dopants into graphene and paving the way for exploring practical Li metal batteries.

关键词： Co-doped graphene lithium metal anode dendrite suppression lithiophilic skeleton solid electrolyte interphase(SEI)formation

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Dynamic changes in butyrate levels regulate satellite cell homeostasis by preventing spontaneous activation during aging

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Science China(Life Sciences) 2024年第4期67卷 745-764页

作者： Shujie Chen liujing Huang Bingdong liu Huimin Duan Ze Li yifan liu Hu Li Xiang Fu Jingchao Lin Yinlan Xu Li liu Dan Wan Yulong Yin Liwei Xie Department of Endocrinology and Metabolism Zhujiang HospitalSouthern Medical UniversityGuangzhou 510280China State Key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Open Laboratory of Applied MicrobiologyInstitute of MicrobiologyGuangdong Academy of SciencesGuangzhou 510070China School of Public Health Xinxiang Medical UniversityXinxiang 453003China Department of Infectious Diseases Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China Metabo-Profile Biotechnology(Shanghai)Co.Ltd. Shanghai 201315China Institute of Aging Research Guangdong Provincial Key Laboratory of Medical Molecular DiagnosticsSchool of Medical TechnologyGuangdong Medical UniversityDongguan 524023China Department of Rehabilitation Medicine Nanfang HospitalSouthern Medical UniversityGuangzhou 510000China Laboratory of Animal Nutritional Physiology and Metabolic Process Key Laboratory of Agro-ecological Processes in Subtropical RegionInstitute of Subtropical AgricultureChinese Academy of SciencesChangsha 410125China Bioland Laboratory Guangzhou Regenerative Medicine and Health Guangdong LaboratoryGuangzhou 510005China

The gut microbiota plays a pivotal role in systemic metabolic processes and in particular functions,such as developing and preserving the skeletal muscle ***,the interplay between gut microbiota/metabolites and the regulation of satellite cell(SC)homeostasis,particularly during aging,remains *** propose that gut microbiota and its metabolites modulate SC physiology and homeostasis throughout skeletal muscle development,regeneration,and aging *** investigation reveals that microbial dysbiosis manipulated by either antibiotic treatment or fecal microbiota transplantation from aged to adult mice,leads to the activation of SCs or a significant reduction in the total ***,employing multi-omics(e.g.,RNA-seq,16S r RNA gene sequencing,and metabolomics)and bioinformatic analysis,we demonstrate that the reduced butyrate levels,alongside the gut microbial dysbiosis,could be the primary factor contributing to the reduction in the number of SCs and subsequent impairments during skeletal muscle ***,butyrate supplementation can mitigate the antibiotics-induced SC activation irrespective of gut microbiota,potentially by inhibiting the proliferation and differentiation of SCs/*** butyrate effect is likely facilitated through the monocarboxylate transporter 1(Mct1),a lactate transporter enriched on membranes of SCs and *** a result,butyrate could serve as an alternative strategy to enhance SC homeostasis and function during skeletal muscle *** findings shed light on the potential application of microbial metabolites in maintaining SC homeostasis and preventing skeletal muscle aging.

关键词： gut microbiota aging satellite cells butyrate Slc16a1(Mct1)

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Anti-Jamming Null Space Projection Beamforming Based on Symbiotic Radio

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工程与科学中的计算机建模(英文) 2024年第1期138卷 679-689页

作者： Baofeng Ji yifan liu Tingpeng Li Ling Xing Weixing Wang Shahid Mumtaz Xiaolong Shang Wanying liu Congzheng Han State Key Laboratory of Complex Electromagnetic Environment Effects on Electronics and Information System(CEMEE) Luoyang471000China Research and Innovation Center of Intelligent System Longmen LaboratoryLuoyang471000China College of Information Engineering Henan University of Science and TechnologyLuoyang471000China Institute of Atmospheric Physics Chinese Academy of Sciences(LAGEO)Beijing100000China Instituto de Telecomunicaes Aveiro3800-005Portugal Chinese Academy of Agricultural Mechanization Sciences Beijing100000China

With the development of information technology,more and more devices are connected to the Internet through wireless communication to complete data *** to the broadcast characteristics ofwireless channels,wireless networks have suffered more and more malicious *** layer security has received extensive attention from industry and *** is considered to be one of the most important technologies related to physical layer *** beamforming technology,messages can be transmitted to legitimate users in an offset direction that is as orthogonal as possible to the interference channel to ensure the reception SINR by legitimate *** the symbiotic radio(SR)technology,this paper considers a symbiotic radio antijamming MIMO system equipped with a multi-antenna system at the main base *** order to avoid the interference signal and improve the SINR of the signal received by the *** base station is equipped with a uniform rectangular antenna array,and using Null Space Projection(NSP)Beamforming,Intelligent Reflecting Surface(IRS)can assist in changing the beam’s *** simulation results show that NSP Beamforming could make a better use of the null space of interference,which can effectively improve the received SINR of users under directional interference,and improve the utilization efficiency of signal energy.

关键词： Symbiotic radio anti-jamming MIMO NSP Beamforming physical layer security

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Distal margin distance in radical resection of locally advanced rectal cancer after neoadjuvant therapy

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Chinese Journal of Cancer Research 2024年第2期36卷 226-232页

作者： Jun Luo Mingxuan Zhu Long Zhao Meiwen He Bei Li yifan liu Yuhan Sun Guoqing Lyu Zhanlong Shen Department of Gastrointestinal Surgery Peking University Shenzhen HospitalShenzhen 518036China Department of Gastroenterological Surgery Laboratory of Surgical OncologyBeijing Key Laboratory of Colorectal Cancer Diagnosis and Treatment ResearchPeking University People's HospitalBeijing 100044China School of Medicine the Chinese University of Hong KongShenzhen 518172China

Colorectal cancer has a high incidence and mortality rate in China, with the majority of cases being middle and low rectal cancer. Surgical intervention is currently the main treatment modality for locally advanced rectal cancer, with the common goal of improving oncological outcomes while preserving function. The controversy regarding the circumferential resection margin distance in rectal cancer surgery has been resolved. With the promotion of neoadjuvant therapy concepts and advancements in technology, treatment strategies have become more *** tumor downstaging, there is an increasing trend towards extending the safe distance of distal rectal margin. This provides more opportunities for patients with low rectal cancer to preserve their anal ***, there is currently no consensus on the specific distance of distal resection margin.

关键词： Colorectal cancer distal resection margin neoadjuvant therapy

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中国民间龙女形象的佛教文化溯源

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宗教学研究 2024年第3期 114-118页

作者：刘怡凡四川大学道教与宗教文化研究所

龙女是中国传统文化中非常受人喜爱的形象,她不仅作为胁侍与善财童子一同出现在观音菩萨的造像中,也同时以善良美丽的仙女形象出现在各种传奇小说、雕塑作品中。龙女在佛教文献中原本具有可变化为人、与人通婚然受龙类业报之苦等多种形... 详细信息

龙女是中国传统文化中非常受人喜爱的形象,她不仅作为胁侍与善财童子一同出现在观音菩萨的造像中,也同时以善良美丽的仙女形象出现在各种传奇小说、雕塑作品中。龙女在佛教文献中原本具有可变化为人、与人通婚然受龙类业报之苦等多种形象,但传入中国后经过文学创作的再加工,民间龙女形象脱离了佛教众多的龙女原型,趋向完全正面的女性形象。通过梳理佛教文献可以还原出龙女形象在中国的原型及变形。

关键词：佛教文献善财童子中国传统文化传奇小说文化溯源雕塑作品龙女胁侍

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乡村振兴战略下县域城乡融合发展的实践路径

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学习论坛 2024年第5期 78-86页

作者：刘一凡郑州航空工业管理学院文法学院河南郑州450015

推进县域城乡融合发展是全面建设社会主义现代化国家的核心目标之一。立足于中国式现代化的必然要求、城乡关系发展的整体趋向以及实现乡村振兴的政策目标,我国县域城乡融合取得了农民生活质量得到显著提升、农村面貌焕然一新、农业现... 详细信息

推进县域城乡融合发展是全面建设社会主义现代化国家的核心目标之一。立足于中国式现代化的必然要求、城乡关系发展的整体趋向以及实现乡村振兴的政策目标,我国县域城乡融合取得了农民生活质量得到显著提升、农村面貌焕然一新、农业现代化水平不断提升等阶段性进展和实际成效。但在县域经济发展、要素配置以及制度建设上,仍存在农村经济基础依然薄弱、城乡资源要素协调性发展欠佳、城乡融合发展体制机制有待加强等不可忽视的现实困境。在党的二十届三中全会精神的全面指引下,可从夯实乡村经济基底、推动要素合理配置、筑牢制度框架三个方面推进县域城乡融合发展的实践路径,为乡村振兴战略下促进县域城乡融合发展提供理论支撑和决策参考。

关键词：乡村振兴县域城乡融合城乡关系生产要素

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北极三维云结构的时空变化:季节变化

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极地研究 2024年第2期36卷 140-156页

作者：冯时杰黄菲刘一凡张艺凡周腾中国海洋大学海洋与大气学院山东青岛266100 深海多圈层与地球系统前沿科学中心和物理海洋实验室中国海洋大学山东青岛266100 中国海洋大学未来海洋学院山东青岛266100

本文基于2007-2020年多年气候月平均的CALIPSO云量的三维空间数据,研究了北极云量三维结构的气候态及季节变化特征。结果表明,北极的云量主要分布在大气边界层和对流层中,从边界层向上云量递减;水平空间分布主要表现出显著的海陆差异,... 详细信息

本文基于2007-2020年多年气候月平均的CALIPSO云量的三维空间数据,研究了北极云量三维结构的气候态及季节变化特征。结果表明,北极的云量主要分布在大气边界层和对流层中,从边界层向上云量递减;水平空间分布主要表现出显著的海陆差异,云量最大值出现在北极大西洋扇区;垂向结构表现出对流层上下同位相变化的正压结构和低空大气边界层与对流层中上层反位相变化的一阶斜压模结构,在边界层中北冰洋海洋上空的云量大于北极陆地上空的云量,而在对流层中上层则正好相反。北极云量主要呈现出单峰型的季节变化特征, 2-3月云量最少, 9月云量最多。北极云量的季节变化主要体现在低空大气边界层云量的两个时空主模态变化中,第一模态主要反映了北极融冰期(5-10月)和结冰期(11月至次年4月)云量的反位相变化,方差贡献为59.35%;第二模态则主要体现了深秋(10-11月)和初夏(6-7月)北极地区海陆差异的反位相变化特征,方差贡献为19.22%。

关键词：北极云量垂直结构季节变化海陆差异

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新型纳米睫状神经营养因子复合物玻璃体腔注射对食蟹猴眼部的安全性——形态学评价

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中华实验眼科杂志 2024年第7期42卷 613-620页

作者：张天璐刘一帆沈吟武汉大学人民医院眼科中心武汉430060 武汉大学医学研究院武汉430071

目的评估一种新型纳米神经营养因子复合物(NP-CNTFs)在非人灵长类动物眼内应用的安全性。方法利用纳米工艺制备包裹睫状神经营养因子(CNTF)的纳米粒。选取3只成年雄性食蟹猴,单眼玻璃体腔注射10μl NP-CNTFs(1μg/μl)作为NP-CNTFs组,... 详细信息

目的评估一种新型纳米神经营养因子复合物(NP-CNTFs)在非人灵长类动物眼内应用的安全性。方法利用纳米工艺制备包裹睫状神经营养因子(CNTF)的纳米粒。选取3只成年雄性食蟹猴,单眼玻璃体腔注射10μl NP-CNTFs(1μg/μl)作为NP-CNTFs组,对侧眼注射等体积磷酸盐缓冲液作为对照组。在注射前、注射后第3天和第7天,对食蟹猴行常规眼前节检查以评估结膜充血、前房闪辉及前房细胞等眼部症状并评分;采用彩色眼底照相观察眼底情况;采用频域光学相干断层扫描(SD-OCT)检测视网膜形态结构及厚度。结果所制备NP-CNTFs粒径为(317±3)nm,多分散性指数为0.042±0.015,Zeta电位为(-38.9±0.7)mV,具备较好的稳定性、生物利用度和生物相容性。眼前节检查显示,NP-CNTFs组在注射后第3天表现出较对照组稍明显的结膜充血、前房闪辉和前房细胞,但在注射后第7天基本恢复正常。NP-CNTFs组与对照组注射后第3天眼前节症状评分分别为(2.67±0.88)和(1.00±0.58)分,注射后第7天分别为(0.67±0.33)和(0.33±0.33)分,组间比较差异均无统计学意义(t=2.50、1.00,均P>0.05)。彩色眼底照相结果显示,NP-CNTFs组和对照组在注射后第7天眼底均正常,未见玻璃体混浊、玻璃体出血、视网膜出血或视盘水肿等异常改变。SD-OCT结果显示,NP-CNTFs组和对照组在注射后第7天均未见明显视网膜组织学改变。NP-CNTFs组和对照组视网膜神经纤维层厚度分别为(107.67±0.88)和(111.00±3.22)μm,黄斑中央凹厚度分别为(255.67±2.03)和(254.67±3.84)μm,组间比较差异均无统计学意义(t=1.43、0.50,均P>0.05)。结论新型纳米药物NP-CTNFs在食蟹猴眼内应用的安全性较好。

关键词：纳米粒睫状神经营养因子食蟹猴安全性评估

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