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2003—2019年上海市嘉定区结直肠癌流行趋势研究

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中国全科医学 2024年第10期27卷 1261-1266页

作者：陈单王亚伟黄芳徐一凡张一英邵月琴复旦大学公共卫生学院上海市200032 上海市嘉定区疾病预防控制中心 201800

背景结直肠癌已成为上海市嘉定区发病率排名第三的恶性肿瘤,其疾病负担仍在加重。目的分析2003—2019年上海市嘉定区结直肠癌流行趋势,为结直肠癌防治提供科学依据。方法基于2003—2019年上海市嘉定区肿瘤登记资料,计算粗发病率、粗死... 详细信息

背景结直肠癌已成为上海市嘉定区发病率排名第三的恶性肿瘤,其疾病负担仍在加重。目的分析2003—2019年上海市嘉定区结直肠癌流行趋势,为结直肠癌防治提供科学依据。方法基于2003—2019年上海市嘉定区肿瘤登记资料,计算粗发病率、粗死亡率、标化发病率、标化死亡率等统计指标(以2010年中国标准人口构成进行标化调整),利用Joinpoint Regression Program 4.***.1.0软件分析发病率和死亡率的变化趋势。结果2003—2019年上海市嘉定区结直肠癌新发病例5020例,粗发病率52.12/10万,标化发病率26.27/10万,死亡病例2419例,粗死亡率25.12/10万,标化死亡率11.16/10万,男性的粗发病率和粗死亡率均高于女性(P<0.05);总人群标化发病率总体呈现上升趋势(APC=2.63%,P<0.05),其中男性标化发病率呈上升趋势(APC=3.48%,P<0.05),女性标化发病率无明显变化趋势(APC=1.39%,P=0.119),均未发现转折点;总人群标化死亡率无明显变化趋势(APC=-0.49%,P=0.250),其中男性标化死亡率无明显变化趋势(APC=0.34%,P=0.545),女性标化死亡率呈现下降趋势(APC=-1.94%,P<0.05)。结论2003—2019年上海市嘉定区结直肠癌总体发病率总体仍有上升,其中男性呈上升趋势,女性无明显变化趋势;总体死亡率无明显变化趋势,其中男性无明显变化,女性呈下降趋势,应继续加强结直肠癌的防控工作,重点关注男性人群。

关键词：结直肠肿瘤发病率死亡率趋势 Joinpoint回归模型上海市

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Functionalization of small black phosphorus nanoparticles for targeted imaging and photothermal therapy of cancer

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Science Bulletin 2018年第14期63卷 917-924页

作者： Lijuan Deng yifan xu Caixia Sun Baofeng Yun Qiao Sun Chongjun Zhao Zhen Li Key Laboratory for Ultrafine Materials of Ministry of Education. Shanghai Key Laboratory of Advanced Polymeric Materials School of Material Science and Engineering East China University of Science and Technology Shanghai 200237 China Center for Molecular imaging and Nuclear Medicine State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences (PAD-X) Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions Soochow University Suzhou 215123 China College of Textile and Clothing Engineering Soochow University Suzhou 215123 China

Black phosphorus(BP) nanomaterials have attracted extensive attention due to their unique physical,chemical, and biological properties. In this study, small BP nanoparticles were synthesized and modified with dextran and poly(ethyleneimine) for functionalization with folic acid and cyanine 7. The functionalized BP nanoparticles exhibit excellent biocompatibility, stability, and near infrared optical properties for targeted imaging of tumors through photoacoustic imaging and near-infrared fluorescence *** also display high photothermal conversion efficiency for photothermal therapy of cancer. This work demonstrates the potential of functionalized small BP nanoparticles as an emerging nanotheranostic agent for the diagnosis and treatment of cancer.

关键词： Black phosphorus Functionalization Targeted imaging Photothermal therapy

The role of periodontal disease in atherosclerotic cardiovascular disease

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BIOCELL 2023年第7期47卷 1431-1438页

作者： XIWEI ZHAO JINSONG WANG yifan xu JIAN ZHOU LEI HU Beijing Laboratory of Oral Health School of Basic MedicineSchool of StomatologyCapital Medical UniversityBeijing100069China Department of Biochemistry and Molecular Biology School of Basic MedicineCapital Medical UniversityBeijing100069China Immunology Research Center for Oral and Systemic Health Beijing Friendship HospitalCapital Medical UniversityBeijing100050China Research Unit of Tooth Development and Regeneration Chinese Academy of Medical SciencesBeijing100700China Department of VIP Dental Service School of StomatologyCapital Medical UniversityBeijing100050China

Atherosclerotic cardiovascular disease(ASCVD)includes a group of disorders of the heart and blood vessels and accounts for major morbidity and premature death *** is a chronic inflammatory disease with the gradual destruction of supporting tissues around the teeth,including gingiva,periodontal ligament,alveolar bone,and *** has been found to potentially increase the risk of ***,oral microorganisms and inflammation are the major factors for periodontitis to the incidence of ***,evidence has shown that the loss of masticatory function is another important factor of periodontitis to the incidence of *** this review,we illustrate the recent finding of the relationship between periodontitis and ASCVD,from a microscale perspective-oral microorganisms,inflammation,and tooth *** the high prevalence of periodontitis,it is important to add oral therapy as a regular ASCVD prevention *** dental visits could be a helpful strategy for ASCVD patients or general medical practitioners.

关键词： Oral microorganisms Chronic infection Tooth loss Periodontitis Atherosclerotic cardiovascular disease

A fiber-reinforced solid polymer electrolyte by in situ polymerization for stable lithium metal batteries

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Nano Research 2023年第7期16卷 9259-9266页

作者： yifan xu Ruo Zhao Lei Gao Tingsong Gao Wenjuan Wang Juncao Bian Songbai Han Jinlong Zhu Qiang xu Yusheng Zhao Institute for Advanced Study Shenzhen UniversityShenzhen 518055China Guangdong Provincial Key Laboratory of Energy Materials for Electric Power Guangdong-Hong Kong-Macao Joint Laboratory for Photonic-Thermal-Electrical Energy Materials and DevicesAcademy for Advanced Interdisciplinary StudiesSouthern University of Science and TechnologyShenzhen 518055China Shenzhen Key Laboratory of Micro/Nano-Porous Functional Materials Department of Materials Science and EngineeringSouthern University of Science and TechnologyShenzhen 518055China School of Materials Science and Engineering Peking UniversityBeijing 100871China

Solid polymer electrolytes(SPEs)by in situ polymerization are attractive due to their good interfacial contact with *** reported in situ polymerized SPEs,however,suffer from the low polymerization degree that causes poor mechanical strength,Li dendrite penetration,and performance decay in Li-metal *** highly polymerized SPEs are more stable than lowly polymerized ones,they are restricted by their sluggish long-chain mobility and poor ionic *** this work,a three-dimensional fibrous membrane with ion selectivity was prepared and used as a functional filler for the in situ formed *** obtained SPE has high stability due to its high polymerization degree after the long-term heating *** fibrous membrane plays a vital role in improving the SPE’s *** rich anion-adsorption sites on the fibrous membrane can alleviate the polarization effect and benefit a uniform current distribution at the *** fibrous nanostructure can efficiently interact with the polymeric matrix,providing rich hopping sites for fast Li+***,the obtained SPE enables a uniform Li deposition and long-term cycling performance in Li-metal *** work reported an in situ formed SPE with both high polymerization degree and ionic conductivity,paving the way for designing high-performance SPEs with good comprehensive properties.

关键词： solid polymer electrolytes fibrous solid filler metal-organic frameworks in situ polymerization ion selectivity

Transformers in computational visual media:A survey

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Computational Visual Media 2022年第1期8卷 33-62页

作者： yifan xu Huapeng Wei Minxuan Lin Yingying Deng Kekai Sheng Mengdan Zhang Fan Tang Weiming Dong Feiyue Huang Changsheng xu NLPR Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100040China School of Artificial Intelligence Jilin UniversityChangchun 130012China Youtu Lab Tencent Inc.Shanghai 200233China CASIA-LLVISION Joint Lab Beijing 100190China

Transformers,the dominant architecture for natural language processing,have also recently attracted much attention from computational visual media researchers due to their capacity for long-range representation and high *** are sequence-to-sequence models,which use a selfattention mechanism rather than the RNN sequential ***,such models can be trained in parallel and can represent global *** study comprehensively surveys recent visual transformer *** categorize them according to task scenario:backbone design,high-level vision,low-level vision and generation,and multimodal *** key ideas are also *** from previous surveys,we mainly focus on visual transformer methods in low-level vision and *** latest works on backbone design are also reviewed in *** ease of understanding,we precisely describe the main contributions of the latest works in the form of *** well as giving quantitative comparisons,we also present image results for low-level vision and generation *** costs and source code links for various important works are also given in this survey to assist further development.

关键词： visual transformer computational visual media(CVM) high-level vision low-level vision image generation multi-modal learning

Persymmetric adaptive polarimetric detection of subspace range-spread targets in compound Gaussian sea clutter

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Journal of Systems Engineering and Electronics 2024年第1期35卷 31-42页

作者： xu Shuwen HAO yifan WANG Zhuo xuE Jian National Key Laboratory of Radar Signal Processing Xidian UniversityXi’an 710071China Xi’an Electronic Engineering Research Institute Xi’an 710100China Beijing Institute of Radio Measurement Beijing 100039China School of Communications and Information Engineering Xi’an University of Posts and TelecommunicationsXi’an 710121China

This paper focuses on the adaptive detection of range and Doppler dual-spread targets in non-homogeneous and nonGaussian sea *** sea clutter from two polarimetric channels is modeled as a compound-Gaussian model with different parameters,and the target is modeled as a subspace rangespread target *** persymmetric structure is used to model the clutter covariance matrix,in order to reduce the reliance on secondary data of the designed *** adaptive polarimetric persymmetric detectors are designed based on the generalized likelihood ratio test(GLRT),Rao test,and Wald *** the proposed detectors have constant falsealarm rate property with respect to the clutter texture,the speckle covariance *** results on simulated and measured data show that three adaptive detectors outperform the competitors in different clutter environments,and the proposed GLRT detector has the best detection performance under different parameters.

关键词： sea clutter adaptive polarimetric detection compound Gaussian model subspace range-spread target persymmetric structure

Synthesis of yolk-shell Bi_(2)O_(3)@TiO_(2) submicrospheres with enhanced potassium storage

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Science China Chemistry 2022年第9期65卷 1807-1816页

作者： yifan xu Hehe Zhang Tangjing Ding Ruiqi Tian Dongmei Sun Ming-Sheng Wang Xiaosi Zhou Jiangsu Key Laboratory of New Power Batteries Jiangsu Collaborative Innovation Center of Biomedical Functional MaterialsSchool of Chemistry and Materials ScienceNanjing Normal UniversityNanjing 210023China State Key Lab of Physical Chemistry of Solid Surfaces College of MaterialsXiamen UniversityXiamen 361005China

Due to their enormous potential for large-scale energy storage,rechargeable potassium-ion batteries have been widely researched and ***,the drastic volume change of electrode materials induced by the huge size of potassium ions during cycling remains a challenge for the construction of stable ***,we propose a novel weak acid etching strategy to design and fabricate robust yolk-shell spheres with enough internal void space,in which the Bi_(2)O_(3) nanospheres are well confined in the compartments of TiO_(2) submicrospheres(y-Bi_(2)O_(3)@TiO_(2)).In situ transmission electron microscopy(TEM)and ex situ Xray diffraction(XRD)are conducted to elucidate the structural evolution of y-Bi_(2)O_(3)@TiO_(2) and the interaction between K^(+)and Bi_(2)O_(3) during *** to the yolk-shell nanoarchitecture and the superior buffering property of outer TiO_(2) covering,the as-obtained composite shows a high specific capacity of 383.5 mAh g^(−1) at 100 mA g^(−1),a considerable rate capacity of 134.1 mAh g^(−1) at 2 A g^(−1) and a stable cycling performance of 216.8 mAh g^(−1) at 500 mA g^(−1) over 500 cycles when used for potassium ***,the potassium-ion full battery,constructed by pairing y-Bi_(2)O_(3)@TiO_(2) anode with the thermally annealed 3,4,9,10-perylenetetracarboxylic dianhydride(PTCDA)cathode,exhibits an outstanding cycling ***,this carefully-designed strategy can inspire the further development of superior energy storage materials in the near future.

关键词： Bi_(2)O_(3) amorphous TiO_(2) yolk-shell structure anode potassium-ion batteries

“7·31”特大暴雨引发的门头沟区地质灾害调研及紧急应对策略研究

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中国应急救援 2024年第1期 72-77页

作者：景鹏旭徐一凡门丽君许杰夫杨清逸长安大学地质工程与测绘学院中国地震应急搜救中心山西工程技术学院中咨(北京)项目管理发展有限公司

2023年7月29日20时至8月2日7时,北京市平均降雨量达到331毫米,门头沟区平均538.1毫米。暴雨导致门头沟地区地质灾害频发、破坏严重,造成巨大的人员伤亡和财产损失。8月中旬,对受灾严重的门头沟区进行深入调研,对洪水、滑坡、崩塌、泥石... 详细信息

2023年7月29日20时至8月2日7时,北京市平均降雨量达到331毫米,门头沟区平均538.1毫米。暴雨导致门头沟地区地质灾害频发、破坏严重,造成巨大的人员伤亡和财产损失。8月中旬,对受灾严重的门头沟区进行深入调研,对洪水、滑坡、崩塌、泥石流、地面塌陷、建筑物倒塌等典型灾害从岩土体性质、灾害规模以及沿途分布特征等方面分析,科学评估其对交通路线、居民房屋的危害,并针对性提出应急处置建议和恢复重建建议,以期对今后北京市遭遇极端暴雨天气出现的地质灾害问题提供对策和技术支撑。在此基础之上,对现有的应急预案进行分析并提出改进建议,从事前、事中、事后三阶段深层次的分析政府、社区、乡镇、各部门、企事业单位、人民群众等不同主体在应对此次极端暴雨天气的暴露出的弊端和值得借鉴之处,为今后应对此类灾害提供参考。

关键词：特大暴雨地质灾害应急处置恢复重建应急救援预案

自我建构视阈下时间压力对消费者购买意愿的影响

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北华大学学报（社会科学版） 2024年第3期25卷 93-103,154页

作者：张洪利周妍徐一帆江黎静吉林大学商学与管理学院长春130012 中国人民大学商学院北京100872

电子商务平台通过限时、限量策略激发消费者购买意愿的现象非常普遍,饥饿营销已发展成现代企业营销的重要手段。时间压力对消费者购买意愿具有很大影响,探究其内在机制有利于构建饥饿营销的解释模型。通过两个实验发现,高强度时间压力... 详细信息

电子商务平台通过限时、限量策略激发消费者购买意愿的现象非常普遍,饥饿营销已发展成现代企业营销的重要手段。时间压力对消费者购买意愿具有很大影响,探究其内在机制有利于构建饥饿营销的解释模型。通过两个实验发现,高强度时间压力会唤起消费者的感知竞争进而提高其购买意愿,而且消费者自我建构类型会调节时间压力对消费者购买意愿的影响,即相较于独立型消费者,依存型自我建构消费者将感知到更强程度的竞争,购买意愿更强烈。从消费者心理角度考察时间压力与消费者购买意愿之间具有密切关系,对现代企业饥饿营销策略的科学运用具有重要的现实意义。

关键词：饥饿营销时间压力购买意愿感知竞争自我建构