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Journal of Mountain Science 2013年第5期10卷 885-897页

作者： fang yi-ping Institute of Mountain Hazards& Environment Chinese Academy of Sciences

The interaction among different livelihood capitals is a key to generate a deeper understanding of the livelihood *** this paper,we use net income per capita(economic capital),meat and milk production per capita(physical capital),and areas of fenced pasture,livestock shelter,grassland rodent control and planted grassland(physical capital) as proxy indicators of livelihood promotion,livelihood provision,and livelihood protection *** developing a correlation model between pastoralists' livelihood protection and improvement,we found that(1) there is a statistically significant correlation between the pastoralists' livelihood protection and promotion;(2) based on the maximum effect of pastoralists' livelihood promotion and provision,there is a benchmark in the effect of the intervention intensity of livelihood capital(grassland resource protection) on livelihood improvement;(3) on basis of two indicators,*** income per capita and meat production per capita,the reasonable scales of fenced pasture,livestock shelter and planted grassland are less than 843,860 and 46 thousand hectares(hm2) per year *** the marginal effect of livelihood protection,moderately decreased areas of fenced pasture and planted grassland,and increased area of livestock shelter is a critical to ensure pastoralist's livelihood sustainability.

关键词： Regional sustainability Natural capitalprotection Pastoralist's livelihood Source Region ofthe Yellow River

Changes in the food supply capacity of alpine grassland ecosystem:A dialectic synthesis of natural and anthropogenic drivers

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Advances in Climate Change Research 2020年第1期11卷 1-10页

作者： fang yi-Ping Institute of Mountain Hazards&Environment Chinese Academy of SciencesChengdu610041China College of Resource and Environment University of Chinese Academy of SciencesBeijing100049China

Grassland-based animal husbandry and livestock production is the main contributor to livelihood creation for *** using the structural dynamics method,this study quantified the changes in the food supply capacity(FSC)of alpine grassland ecosystem and sensitivity to significant *** findings indicated that:i)Natural factors were the dominated forces affecting FSC,and their contribution was 71.3%.Of these natural elements,the net primary productivity(NPP)and precipitation were the largest contributors,accounting for approximately 35%.The sensitivity index of the FSC to NPP and precipitation during grassland growing season were 4.1 and 1.9 *** the contrary,human factors like warm shed area,density of road,capacity for access to information,contributed to 28.7%of the total ***)More intense snow disaster had a larger negative impact on *** disaster can cause dramatic reduction in FSC,with a loss rate of 27.6%and with none intense disaster more negative impacts,iii)The continuing increase of FSC in the past 30 years from 1984 to 2014 was due to the significant increase of precipitation and NPP in the growing season of alpine ***,successful adaptation to climate change was critical to combat the climatic adversely impact on ***,strengthening information dissemination,road accessibility and knowledge popularization of local residents'disaster reduction should be place high priority for improving FSC。

关键词： Food supply capacity Alpine grassland ecosystem Structural dynamics method Snow disaster Permafrost

Decline in semen concentration of healthy Chinese adults： evidence from 9357 participants from 2010 to 2015

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Asian Journal of Andrology 2018年第4期20卷 379-384页

作者： Hong-fang yuan Huang-fang Shangguan yi Zheng Tian-Qing Meng Cheng-Liang Xiong Huang-Tao Guan Family Planning Research Institute Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China College of Informatics Huazhong Agricultural University Wuhan 430070 China Department of Venereology Wuhan Institute of Dermatology and Venereology Wuhan 430031 China Reproductive Medicine Center Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Hubei Province Human Sperm Bank Wuhan 430030 China

The present study aims to analyze sperm concentration trends among young and healthy Chinese adults in Wuhan, Central China, from 2010 to 2015. Semen analysis data from 9357 participants were collected and analyzed using a general linear model and the Cochran-Armitage trend test. A significant decline was observed in sperm concentration （β [standard deviation]： -1.53 [0.16]; P 〈 0.001）. In addition, a decline in sperm density was observed by stratifying student versus nonstudent sperm donors and by analyzing the year of birth or birth year cohort of the participants. Furthermore, the percentage of participants with sperm densities of over 40×10^6 ml^-1 significantly decreased with year. Notably, a dramatic decline in sperm density was recorded over the first 5 years of study.

关键词： healthy men semen concentration sperm donors temporal trends

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扭曲双层石墨烯的层间电导特性研究

原子与分子物理学报 2025年第6期42卷 83-88页

作者：陶懿洲刘超方贺男南京邮电大学电子与光学工程学院南京210023

扭曲双层石墨烯(TBG)由于具有莫特绝缘和非常规超导等新奇的电学特性,在纳米技术领域存在巨大的应用潜力.本文基于光学衍射物理方法,构建了一个适用于TBG的理论模型,并利用该理论模型研究了TBG的层间电导特性.研究结果较好地解释了TBG... 详细信息

扭曲双层石墨烯(TBG)由于具有莫特绝缘和非常规超导等新奇的电学特性,在纳米技术领域存在巨大的应用潜力.本文基于光学衍射物理方法,构建了一个适用于TBG的理论模型,并利用该理论模型研究了TBG的层间电导特性.研究结果较好地解释了TBG层间电导随扭转角变化的实验结果,并阐明了其物理机制.此外,本文还计算了电极参数、隧穿层厚度以及界面势强度等物理因素对层间电导特性的影响.计算结果表明:随着电极化学势的增大,层间电导关于扭转角的变化曲线近似整体向上平移;层间电导随着上层隧穿层厚度的增加而衰减并趋于稳定,而随着下层隧穿层厚度振荡;TBG两层扭转石墨烯的界面势强度越强,则层间电导随扭转角下降得越快.

关键词：低维物理层间电导光学衍射方法扭曲双层石墨烯

Immunotherapeutic strategies targeting B cell maturation antigen in multiple myeloma

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Military Medical Research 2021年第3期8卷 433-443页

作者： yi fang Jian Hou Department of Hematology Renji HospitalSchool of MedicineShanghai Jiao Tong University160 Pujian RoadShanghai 200127China

Multiple myeloma(MM) is the second most common hematologic malignancy, and is characterized by the clonal expansion of malignant plasma cells. Despite the recent improvement in patient outcome due to the use of novel therapeutic agents and stem cell transplantation, all patients eventually relapse due to clone evolution. B cell maturation antigen(BCMA) is highly expressed in and specific for MM cells, and has been implicated in the pathogenesis as well as treatment development for MM. In this review, we will summarize representative anti-BCMA immune therapeutic strategies, including BCMA-targeted vaccines, anti-BCMA antibodies and BCMA-targeted CAR cells. Combination of different immunotherapeutic strategies of targeting BCMA, multi-target immune therapeutic strategies, and adding immune modulatory agents to normalize anti-MM immune system in minimal residual disease(MRD) negative patients, will also be discussed.

关键词： B cell maturation antigen Multiple myeloma Vaccine Antibody CAR T-cells

Non-formation of vacuum states for Navier-Stokes equations with density-dependent viscosity

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第10期8卷 1681-1690页

作者： ZHANG Ting fang Dao-yuan Department of Mathematics Zhejiang University Hangzhou 310027 China

We consider the Cauchy problem, free boundary problem and piston problem for one-dimensional compressible Navier-Stokes equations with density-dependent viscosity. Using the reduction to absurdity method, we prove that the weak solutions to these systems do not exhibit vacuum states, provided that no vacuum states are present initially. The essential re- quirements on the solutions are that the mass and energy of the fluid are locally integrable at each time, and the Lloc1-norm of the velocity gradient is locally integrable in time.

关键词： Compressible Navier-Stokes equations Vacuum states Density-dependent viscosity

Phase separation in RNA biology

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Journal of Genetics and Genomics 2021年第10期48卷 872-880页

作者： yi Lin Xiaofeng fang School of Life Sciences Tsinghua UniversityBeijing 100084China

The formation of biomolecular condensates via liquid-liquid phase separation(LLPS)is an advantageous strategy for cells to organize subcellular compartments for diverse *** involvement of LLPS is more widespread and overrepresented in RNA-related biological *** is in part because that RNAs are intrinsically multivalent macromolecules,and the presence of RNAs affects the formation,dissolution,and biophysical properties of biomolecular condensates formed by *** studies have illustrated how LLPS participates in RNA transcription,splicing,processing,quality control,translation,and *** interconnected regulation between LLPS and RNAs ensures tight control of RNA-related cellular functions.

关键词： Phase separation RNA biology Condensates Membrane-less organelle

音乐疗法协同笑气吸入镇静技术缓解重度儿童牙科畏惧症临床应用研究

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中国实用口腔科杂志 2017年第4期10卷 245-249页

作者：王一珠李锐常平吕岩李晓光温丽梁乙然袁一方郭斌中国人民解放军总医院口腔医学中心北京100853

目的探讨音乐疗法协同笑气吸入镇静技术缓解重度儿童牙科畏惧症的有效性。方法于2015年12月至2016年12月在中国人民解放军总医院儿童口腔科筛选需口腔治疗但经儿童畏惧调查-牙科分量表(children′s fear survey schedule-dental subscal... 详细信息

目的探讨音乐疗法协同笑气吸入镇静技术缓解重度儿童牙科畏惧症的有效性。方法于2015年12月至2016年12月在中国人民解放军总医院儿童口腔科筛选需口腔治疗但经儿童畏惧调查-牙科分量表(children′s fear survey schedule-dental subscale,CFSS-DS)确定畏惧程度为4~5级的4~10岁重度牙科畏惧患儿60例作为研究对象。患儿随机分为两组:试验组患儿(30例)进行音乐疗法协同笑气吸入镇静技术治疗;对照组患儿(30例)仅进行笑气吸入镇静技术治疗。在口腔治疗前、笑气使用前、治疗中分别测量两组患儿心率、血压、血氧饱和度等生理指标。治疗过程中,麻醉医生记录镇静起效时间、治疗持续时间及患儿复苏时间。结果对照组30例患儿中有21例(70.0%)完成治疗,9例因畏惧无法缓解而中止治疗;试验组中26例(86.7%)完成治疗,4例中止治疗。试验组笑气镇静起效时间和口腔治疗持续时间明显少于对照组。试验组患儿治疗中情绪稳定,依从性良好,与治疗前、笑气使用前比较,心率、收缩压无显著增高甚至明显降低,舒张压和血氧饱和度无明显变化。结论音乐疗法显著提高笑气缓解CFSS-DS 4级以上牙科畏惧症患儿紧张情绪的有效性和工作效率,提高患儿口腔诊疗依从性,是一种有效、简便的行为管理辅助方法。

关键词：儿童牙科畏惧症音乐疗法笑气吸入镇静技术

Interface materials for perovskite solar cells

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Rare Metals 2021年第11期40卷 2993-3018页

作者： yi-Heng Zhang yuan Li School of Materials Science and Engineering South China University of TechnologyGuangzhou 510641China

Perovskite solar cells exhibit great potential to become commercial photovoltaic technology due to their high power conversion efficiency,low cost,solution processability,and facile large-area device *** engineering plays a significant role to optimize device *** the anode in the inverted devices,this review introduces the progress on the modification of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)including chemical structure alteration,physical doping,and solution *** present the recent advances of dopant-free hole transport materials widely applied in mesoporous and conventional devices,outlining their innovation with novel molecular design concepts toward promising material properties,and device *** the cathode,various metal oxide and organic electron transport materials are covered and the different modification strategies and related mechanisms are *** importantly,simple synthesis process,inexpensive raw materials and highly reproducible photovoltaic performance are the main consideration for the design of all the interface ***,an outlook and some suggestions regarding the future interface engineering are proposed based on the summary of the current development status and working mechanism of interface materials.

关键词： Perovskite solar cells Interface Hole transport materials Electron transport materials PEDOT:PSS

Recent progress on printable power supply devices and systems with nanomaterials

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Nano Research 2018年第6期11卷 3065-3087页

作者： yuanjing Lin yuan Gao fang fang Zhiyong Fan Department of Electronic and Computer Engineering The Hong Kong University of Science and Technology Hong Kong China Department of Materials Science Fudan University Shanghai 200433 China

In recent years, tremendous research interest has been triggered in the fields of flexible, wearable and miniaturized power supply devices and self-powered energy sources, in which energy harvesting/conversion devices are integrated with energy storage devices into an infinitely self-powered energy system. As opposed to conventional fabrication methods, printing techniques hold promising potency for fabrication of power supply devices with practical scalability and versatility, especially for applications in wearable and portable electronics. To further enhance the performance of the as-fabricated devices, the utilization of nanomaterials is one of the promising strategies, owing to their unique properties. In this review, an overview on the progress of printable strategies to revolutionize the fabrication of power supply devices and integrated system with attractive form factors is provided. The advantages and limitations of the commonly adopted printing techniques for power supply device fabrication are first summarized. Thereafter, the research progress on novel developed printable energy harvesting and conversion devices, including solar cells, nanogenerators and biofuel cells, and the research advances on printable energy storage devices, namely, supercapacitors and rechargeable batteries, are presented, respectively. Although exciting advances on printable material modification, innovative fabrication methods and device performance improvement have been witnessed, there are still several challenges to be addressed to realize fully printable fabrication of integrated self-powered energy sources.

关键词： printing techniques energy conversion energy storage integrated self-powered system