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Strategy for Enhancing the Available Capacity of Distribution Networks Considering Electric Vehicle Charging Modes

Dianwang Jishu/Power System Technology 2025年第1期49卷 177-186页

作者： chen, Peng Liu, Youbo Yuan, Chuan Tang, Donglai xiang, Yue Liu, Junyong College of Electrical Engineering Sichuan University Sichuan Province Chengdu 610065 China State Grid Sichuan Electric Power Company Sichuan Province Chengdu 610041 China Aostar Information Technology Co. Ltd. Sichuan Province Chengdu 610067 China

The available capacity of distribution networks represents the maximum load capacity that can be accommodated under the existing conditions of the distribution network. It is an essential indicator for evaluating distribution networks' planning and operational effectiveness. This paper proposes a grid transformation method for distribution networks considering electric vehicle charging modes to address the significant decrease in available capacity caused by the large-scale disorderly charging of electric vehicles. By optimizing the grid topology and the optimal number, location, and type of line expansion and energy storage investment within the limited investment., the optimal enhancement of available capacity is achieved. Firstly, the Monte Carlo method is employed to generate scenarios of disorderly charging of electric vehicles, and an orderly electric vehicle charging model based on optimizing charging schedules is constructed. Secondly, a transformation model for enhancing the available capacity of distribution networks is developed based on the coordination of network reconfiguration, line expansion, and energy storage investment. Then, the complexity of the model is reduced using the Benders decomposition algorithm, and a commercial solver is employed for the solution. Finally, a case study based on a city's actual distribution network grid is conducted to validate the effectiveness of the proposed strategies for enhancing the available capacity. © 2025 Power System Technology Press. All rights reserved.

关键词： Monte Carlo methods

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iGMDR:Integrated Pharmacogenetic Resource Guide to Cancer Therapy and Research

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Genomics, Proteomics & Bioinformatics 2020年第2期18卷 150-160页

作者： xiang chen yi Guo Xin chen Institute of Pharmaceutical Biotechnology and the First Affiliated Hospital Department of Radiation Oncology Zhejiang University School of MedicineHangzhou 310058China Department of Polymer Science and Engineering and Key Laboratory of Adsorption and Separation Materials and Technologies of Zhejiang Province Zhejiang UniversityHangzhou 310027China Joint Institute for Genetics and Genome Medicine between Zhejiang University and University of Toronto Zhejiang UniversityHangzhou 310058China

Current pharmacogenetic studies have obtained many genetic models that can predict the therapeutic efficacy of anticancer *** some of these models are of crucial importance and have been used in clinical practice,these very valuable models have not been well adopted into cancer research to promote the development of cancer therapies due to the lack of integration and standards for the existing data of the pharmacogenetic *** this purpose,we built a resource investigating genetic model of drug response(iGMDR),which integrates the models from in vitro and in vivo pharmacogenetic studies with different omics data from a variety of technical *** this study,we introduced a standardized process for all integrations,and described how users can utilize these models to gain insights into *** is freely accessible at https://***.

关键词： Genetic model Pharmacogenetics Anticancer drug Cancer Drug response

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船用E500钢在海水中阴极极化氢脆敏感性研究

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装备环境工程 2017年第2期14卷 6-10页

作者：李相波马广义陈祥曦马力中国船舶重工集团公司第七二五研究所海洋腐蚀与防护重点实验室山东青岛266101 海军驻青岛地区装备修理监修室山东青岛266001

目的研究阴极保护电位对E500钢在海水中氢脆敏感性的影响。方法采用慢应变速率拉伸试验(SSRT),同时利用三电极体系进行不同电位极化,并结合扫描电镜进行试样断口观察。结果随着阴极保护电位负移,E500钢在海水中的氢脆敏感性增加,阴极保... 详细信息

目的研究阴极保护电位对E500钢在海水中氢脆敏感性的影响。方法采用慢应变速率拉伸试验(SSRT),同时利用三电极体系进行不同电位极化,并结合扫描电镜进行试样断口观察。结果随着阴极保护电位负移,E500钢在海水中的氢脆敏感性增加,阴极保护电位为-0.95 V(***)时,拉伸试样出现脆性解理断裂特征,电位为-1.00 V时,E500钢断口呈脆性断裂特征。结论根据氢脆系数拟合曲线得出,当氢脆系数达到25%时,E500钢最负阴极保护电位应为-0.913 V。

关键词： E500钢氢脆阴极保护电位

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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang yi-De Zhang Jie chen Hai-Di Fan Wan Wang Bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

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Can patients with mild non-neoplastic lesions diagnosed at baseline screening be safely exempt from surveillance: evidence from multicenter community-based cohorts

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Science China Life Sciences 2025年第1期68卷 263-271页

作者： Siyi He Zhiyi Zhang Guohui Song Zhenhai Wang Chunyun Dai Shipeng Yan Kun Jiang Bingbing Song He Li Maomao Cao Dianqin Sun Fan Yang Xinxin Yan Shaoli Zhang yi Teng Qianru Li Changfa Xia Wanqing chen Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College Department of Gastroenterology Gansu Wuwei Tumor Hospital Cixian Cancer Institute Linzhou Cancer Hospital Center for Disease Control and Prevention of Sheyang County Department of Cancer Prevention and Control Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South University Luoshan Center for Disease Control and Prevention Office for Cancer Control and Research Affiliated Cancer Hospital of Harbin Medical University

Surveillance recommendations for gastric cancer（GC） in current guidelines focused on advanced precancerous lesions and were based on precise diagnosis of severity/extent of baseline lesions. We aimed to develop a less endoscopy-related equipment-dependent risk-stratification tool, and assessed whether mild-precursor-lesion patients can be safely exempt from surveillance. In the multicenter communitybased cohort, 75,051 participants receiving baseline endoscopy were enrolled during 2015–2017 and followed-up until 2021. Cumulative incidence rates（CIRs） of GC for precancerous-conditions were calculated by Kaplan-Meier method and compared by Log-rank tests. Mixedeffects Cox regression models were used to detect potential factors for progression towards GC. A risk score was calculated as counts of selected factors. An independent cohort, including 26,586 participants was used for external validation. During a median follow-up of 6.25 years, CIRs of GC were 0.302%, 0.436%, and 4.756% for normal group, non-neoplastic（atrophic gastritis/intestinal metaplasia） and neoplastic lesions（low-grade/high-grade dysplasia）, respectively(Ptrend<0.001). Four predictors, including male, ≥60 years, smoking, and limited vegetable consumption, were selected for risk-stratification. High-risk patients（≥3 risk factors） with non-neoplastic lesions showed higher GC risks（adjusted HR=7.73, 95%CI: 4.29–13.92）, and their four-year CIR reached the one-year CIR of neoplastic lesions. Further categorizing non-neoplastic lesions by histological grade, both patients with moderate-to-severe lesions（aHR=3.07, 95%CI: 1.67–5.64） and high-risk patients with mild lesions（aHR=7.29, 95%CI: 3.58–14.86） showed higher risks. Consistent trends were observed in validation cohort. High-risk mild-precursor-lesion patients should receive surveillance within 3–5 years after baseline screening. Our study provides evidence on supplementing current guideline recommendations.

关键词： stomach neoplasms precancerous conditions cancer screening cumulative incidence risk stratification

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微服务在智慧城市平台建设中的应用初探

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计算技术与自动化 2019年第3期38卷 136-140页

作者：向逸尘林浩宇徐源上海五零盛同信息科技有限公司

我国目前对智慧城市建设的投入越来越大,各类平台软件层出不穷,但各种问题也随之涌现,如何彻底消除信息孤岛,形成真正的信息互联互通,仍然是需要进行进一步研究的。在这种背景下,通过分析智慧城市建设的现状,介绍了微服务设计理念,给出... 详细信息

我国目前对智慧城市建设的投入越来越大,各类平台软件层出不穷,但各种问题也随之涌现,如何彻底消除信息孤岛,形成真正的信息互联互通,仍然是需要进行进一步研究的。在这种背景下,通过分析智慧城市建设的现状,介绍了微服务设计理念,给出了微服务在软件平台建设中进行应用的实现方式,最后对微服务的优势与劣势进行了探讨。

关键词：微服务智慧城市系统集成服务注册服务发现

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合肥市低保家庭的主观幸福感与低保政策支持关系研究

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社会工作 2010年第20期 27-29页

作者：孙见王一美向晨琛安徽大学管理学院安徽合肥230039

城市居民最低生活保障制度的确立保障了城镇贫困家庭的基本生活,同时也催生了低保家庭这一特殊的弱势群体。本研究通过自编的幸福感问卷对合肥城市低保家庭进行幸福感调查,反映了当前合肥市低保家庭的幸福感总体特征、影响因素以及低保... 详细信息

城市居民最低生活保障制度的确立保障了城镇贫困家庭的基本生活,同时也催生了低保家庭这一特殊的弱势群体。本研究通过自编的幸福感问卷对合肥城市低保家庭进行幸福感调查,反映了当前合肥市低保家庭的幸福感总体特征、影响因素以及低保政策与其之间的关系。

关键词：低保家庭主观幸福感政策支持

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SDN中DDoS攻击检测与混合防御技术

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现代电子技术 2025年第2期48卷 85-89页

作者：李小菲陈义河北大学信息技术中心河北保定071002 河北大学计算机教学部河北保定071001

DDoS攻击是软件定义网络(SDN)安全领域的一大威胁,严重威胁网络控制器及交换机等设备的正常运行,因此提出一种SDN中DDoS攻击检测与混合防御技术。在DDoS攻击检测方面,利用卡方检验值对SDN中控制器收到的Packet_In数据流内数据帧数量进... 详细信息

DDoS攻击是软件定义网络(SDN)安全领域的一大威胁,严重威胁网络控制器及交换机等设备的正常运行,因此提出一种SDN中DDoS攻击检测与混合防御技术。在DDoS攻击检测方面,利用卡方检验值对SDN中控制器收到的Packet_In数据流内数据帧数量进行统计分析,将高于数据流卡方阈值的数据流初步判断为可疑流;继续计算数据流与可疑流的相对Sibson距离,区分可疑流是DDoS攻击流还是正常突发流;最后通过计算数据流之间的Sibson距离,根据DDoS攻击流的特征,确定攻击流是否为DDoS攻击流。在DDoS攻击防御方面,采用共享流表空间支持和Packet_In报文过滤方法混合防御,被DDoS攻击的交换机流表空间过载,将过载流表引流到其他交换机,从而完成数据层的防御;溯源得到DDoS攻击MAC地址并进行Packet_In数据流过滤,完成控制层的防御。实验结果表明,所提方法可有效检测软件定义网络交换机和控制器内的DDoS攻击流,能够防御不同的DDoS攻击。

关键词：软件定义网络 DDoS攻击流攻击检测混合防御卡方检验值 Sibson距离流表空间共享

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Homologous CoS2 interface with directed electron transfer and strong chloridion repulsion for efficient seawater oxidation

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Science China Chemistry 2025年

作者： Yuan Tian Jiang-Bo chen Jie ying Ge Tian Yu-Xuan Xiao yi Lu Si-Ming Wu Wei Geng Ling Shen Xiao-Yu Yang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing and School of Materials Science and Engineering and Shenzhen Research Institute & Laoshan Laboratory Wuhan University of Technology School of Chemical Engineering and Technology Sun Yat-Sen University National Energy Key Laboratory for New Hydrogen-Ammonia Energy Technologies Foshan Xianhu Laboratory

Seawater electrolysis is a highly promising method to produce high energy density hydrogen,especially in dry areas that have scarce freshwater ***,application of seawater electrolysis is confronted by two major problems associated with catalysts employed for the anodic oxygen evolution reaction （OER） including the competitive hypochlorite evolution reaction（HCER） and strong chloridion （Cl–） triggered *** studies aimed at overcoming these problems,a facile method has been developed to synthesize a homologous CoS2heterojunction as an OER *** to a difference in work functions at the interface and increased electron density,this material has directed electron transfer and strong chloridion repulsion properties,*** have shown that CoS2achieves low overpotentials of 289 and 322 mV at 10 mA cm-2current density in respective alkaline （1 M KOH） and alkaline simulated seawater ***,the outstanding stability of CoS2is reflected in a negligible decline in activity during promotion of the OER for 100 *** of density functional theory calculations reveal that the homologous CoS2heterojunction promotes directed electron transport for optimizing adsorption/desorption of reactive species and heightens the Cl-adsorption energy for strongly repulsing Cl-,phenomena that enhance OER performance in alkaline simulated seawater.

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Performance Analysis and Evaluation of a Supercritical CO2 Rankine Cycle Coupled with an Absorption Refrigeration Cycle

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Journal of Thermal Science 2020年第4期29卷 1036-1052页

作者： chen yi XU Dongjie chen Zheng GAO xiang REN Fukang HAN Wei China Electric Power Planning&Engineering Institute Beijing 100120China College of Energy Engineering Zhejiang UniversityHangzhou 310058China Power and Mechanical Engineering North China Electric Power UniversityBaoding 071003China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China

The utilization of sensible waste heat such as flue gas and industrial surplus heat is essential for energy saving. Supercritical CO2 power generation cycle is a promising way to be used in this field. In this paper, a new supercritical CO2 Rankine cycle coupled with an absorption refrigeration cycle is proposed, which consists of a reheating supercritical CO2 cycle, a mixed-effect Li Br-H2O absorption refrigeration cycle and solar subsystem including evacuated-tube collector and a hot water storage tank. The system has four variants according to the presence or absence of solar subsystem and net cooling energy output. The thermodynamic model of the proposed system was established and its performance was evaluated. The proposed system is able to realize cascade utilization of flue gas waste heat and efficient conversion of solar energy. It has much higher thermodynamic efficiency than the reference system(i.e., the conventional supercritical CO2 Brayton cycle). Taking combined power and cooling system driven by flue gas waste heat and solar energy as an example, its thermal efficiency and exergy efficiency are 20.37% and 54.18% respectively, compared with the 14.74% and 35.96% of the reference system. Energy Utilization Diagrams(EUD) are implemented to investigate the irreversible losses and variation of the exergy destruction in the energy conversion process. Parametric analysis in two key parameters is conducted to provide guidance for the system optimal design.

关键词： supercritical CO2 cycle absorption refrigeration cycle sensible heat source solar energy thermodynamic analysis

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