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Endogenous biosynthesis of docosahexaenoic acid(DHA)regulates fish oocyte maturation by promoting pregnenolone production

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Zoological Research 2024年第1期45卷 176-188页

作者： yi Li Xuehui Li Ding ye ru Zhang Chengjie Liu Mudan He Houpeng Wang Wei Hu Yonghua Sun State Key Laboratory of Freshwater Ecology and Biotechnology Institute of HydrobiologyInnovation Academy for Seed DesignChinese Academy of SciencesWuhanHubei 430072China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China Hubei Hongshan Laboratory WuhanHubei 430070China

Omega-3 polyunsaturated fatty acids(n-3 PUFAs),particularly docosahexaenoic acid(22:6n-3,DHA),play crucial roles in the reproductive health of vertebrates,including ***,the underlying mechanism related to this phenomenon remains largely *** this study,we employed two zebrafish genetic models,i.e.,elovl2^(-/-)mutant as an endogenous DHAdeficient model and fat1(omega-3 desaturase encoding gene)transgenic zebrafish as an endogenous DHA-rich model,to investigate the effects of DHA on oocyte maturation and *** show that the elovl2^(-/-)mutants had much lower fecundity and poorer oocyte quality than the wild-type controls,while the fat1 zebrafish had higher fecundity and better oocyte quality than wildtype *** deficiency in elovl2^(-/-)embryos led to defects in egg activation,poor microtubule stability,and reduced pregnenolone *** study revealed that DHA promoted pregnenolone synthesis by enhancing transcription of cyp11a1,which encodes the cholesterol side-chain cleavage enzyme,thereby stabilizing microtubule assembly during *** turn,the hypothalamic-pituitary-gonadal axis was enhanced by *** conclusion,using two unique genetic models,our findings demonstrate that endogenously synthesized DHA promotes oocyte maturation and quality by promoting pregnenolone production via transcriptional regulation of cyp11a1.

关键词： Docosahexaenoic acid Oocyte maturation Oocyte quality Pregnenolone Microtubule

Clinical observation on 90 cases of primary dysmenorrhea treated by buccal acupuncture therapy:a randomized controlled study

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Journal of Traditional Chinese Medicine 2024年第1期44卷 172-181页

作者： YANG yi ye Huijun ZHENG Huiling JIN Lihua Department of Obstetrics and Gynecology the Second Affiliated Hospital of Zhejiang Chinese Medical UniversityXinhua Hospital of Zhejiang ProvinceHangzhou 310005China

OBJECTIVE:To explore the short-term and long-term efficacy of buccal acupuncture therapy in the treatment of patients with primary dysmenorrhea(PD).METHODS:A total of 90 patients with PD who were admitted to the Second Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine from January 2020 to December 2021 were included in this study and randomly divided into three groups,including the observation group,the control group,and the placebo group,with 30 patients in each *** in the observation group were treated according to the syndrome types of Traditional Chinese Medicine,those in the control group were treated with Saridon,and those in the placebo group received a *** visual analog scale(VAS)scores of these patients were evaluated at different time points(before treatment,5 min after needle retention,30 min after needle retention,1 h after treatment,2 h after treatment,1 d after treatment,and 2 d after treatment).The Cox Menstrual Symptom Scale(CMSS)scores were assessed before the treatment and after three courses of ***,these two scales were also evaluated during ***,the pain score and adverse reactions of these patients were assessed during ***:After treatment,the VAS and CMSS scores in the observation group decreased significantly(P<0.05)5 and 30 min after needle retention and after ***:Buccal acupuncture therapy is verified to have short-term efficacy in the treatment of *** addition,this therapy has an immediate analgesic effect and long-term efficacy in reducing the severity and frequency of PD.

关键词： buccal acupuncture therapy primary dysmenorrhea pain score randomized controlled trial

Influence of vibration on the lubrication effect of a splash-lubricated gearbox

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第4期25卷 324-339页

作者： yi LIU Kailin ZHANG Shuai SHAO Hongxu XIANG Zhijian ye State Key Laboratory of Rail Transit Vehicle System Southwest Jiaotong UniversityChengdu 610031China

In this study,we investigate the effect of rail vibrations on the lubrication and efficiency of a splash-lubricated gearbox;specifically,the gearbox of a rail-transit vehicle.A high-fidelity 3D numerical model of the gearbox in a moving reference system is described,as well as computational fluid dynamics(CFD)simulations of the gearbox with different vibration *** effects of rotational speed,oil-immersion depth,and different oil-injection volume rates on lubrication and efficiency are *** propose a method of evaluating the internal lubrication condition of a splash-lubricated gearbox and quantitatively compare the effects of different operating parameters on lubrication and ***,our experiment to verify the feasibility of the simulation method is *** results show that with vibration,the churning loss and oil supply for the bearings are significantly higher than those under static *** addition,among different vibrational directions,lateral vibration has the greatest influence on the lubrication condition and efficiency of the *** the studied railway-vehicle gearbox,the best lubrication condition is achieved at a rotational speed of 1600 r/min and an oil-immersion depth of two times the tooth height(***).Rotational speed is the operating parameter that has the most significant effect on the lubrication and efficiencyofthegearbox.

关键词： Comprehensive lubrication evaluation Churning loss Moving reference system Splash lubrication Vibrational excitation Gearbox

Exploiting demand-side heterogeneous flexible resources in risk management of power system frequency

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Science China(Technological Sciences) 2024年第5期67卷 1612-1627页

作者： YAO Yu SONG YongHua ye ChengJin DING yi ZHAO YuMing College of Electrical Engineering Zhejiang UniversityHangzhou310027China State Key Laboratory of Internet of Things for Smart City University of MacaoMacao SAR519000China Shenzhen Power Supply Bureau Co. Ltd.Shenzhen518051China

More demand-side flexible resources(DFRs)are participating in the frequency regulation of renewable power systems,whose heterogeneous characteristics have a significant impact on the system frequency ***,selecting suitable DFRs poses a formidable challenge for independent system operators(ISO).In this paper,a reserve allocation methodology for heterogeneous DFRs is proposed to manage the risk of power system ***,a performance curve is developed to describe the cost,capacity,and response speed of ***,a clustering method for multiple distributed DFRs is conducted to calculate the aggregated performance curves and uncertainty ***,the frequency security criterion considering DFRs’performance is constructed,whose linearity makes it can be easily coupled into the system scheduling model and ***,a risk management model for DFRs considering frequency-chance-constraint is proposed to make a trade-off between cost and frequency ***,the model is transformed into mixed integer second-order cone programming(MISOCP)and solved by the commercial *** proposed model is validated by the IEEE 30 and IEEE 118 bus systems.

关键词： demand-side heterogenous flexible resources risk management of power system frequency performance curve aggregation method mixed integer second-order cone programming

Ultralow friction PTFE/PEEK heterolayer:A new solid lubrication approach toward simplicity

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Friction 2024年第1期12卷 120-135页

作者： Wei SUN Jiaxin ye Qingrui SONG yi FENG Xiaojun LIU School of Materials Science and Engineering Hefei University of TechnologyHefei 230009China Institute of Tribology School of Mechanical EngineeringHefei University of TechnologyHefei 230009China

Tribological applications of polytetrafluoroethylene(PTFE)are often limited by technological complexity to overcome its poor wear ***,a PTFE/polyetheretherketone(PEEK)heterolayer(HL)was proposed and evaluated as a new solid lubrication ***-on-disk tribometry found the lowest friction coefficient(μ)of 0.031 and ultralow wear for the PEEK/HL under typical *** friction coefficient of the HL surpasses those of the state-of-the-art polymeric coatings/composites by at least 200%,and approaches that of highly lubricated *** investigations revealed multi-length physical and chemical heterogeneity of the HL that best facilitates a tribofilm with high subsurface stability and surface *** technological simplicity and robustness of the HL’s high lubricity make it a promising new type of solid lubrication toward greater reliability and longevity.

关键词： ultralow friction anti-wear polytetrafluoroethylene(PTFE) heterolayer(HL)

Synergistic effects of multiscale TiC and dual-phase structure on tensile properties of particle-reinforced steel

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Journal of Iron and Steel Research International 2024年第5期31卷 1232-1245页

作者： ye Jia Xiang-tao Deng Qi Wang Cheng-ru Li Hao Wu Zhao-dong Wang State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819LiaoningChina

The conventional melting methods were used to obtain in situ TiC particle-reinforced dual-phase steel,followed by hot rolling and heat treatment *** aim was to investigate the effect of TiC particles on the fracture behavior of dual-phase steel at different annealing temperatures,by analyzing the microstructure and tensile behavior of the multiscale TiC particle-reinforced dual-phase *** results showed that TiC particles precipitated in the as-cast microstructure of dual-phase steel were distributed along the grain *** hot rolling,the grain boundary-like morphology of the micron-sized TiC particles was disrupted,and the particles became more refined and evenly distributed in the *** tensile tests revealed that the strength of the TiC particle-reinforced dual-phase steel increased with increasing martensite content,while the elongation *** results were similar to those of conventional *** addition of 1 vol.%multiscale TiC particles improved the strength of the dual-phase steel but did not affect elongation of the *** and holes were primarily concentrated around the TiC particles rather than at the interface of martensite and *** main causes of crack sprouting were TiC particle interface cracking and TiC particle internal ***,the study demonstrated the potential of multiscale TiC particle-reinforced dual-phase steel as a strong and tough *** refined distribution of TiC particles in the matrix improved the strength of the material without compromising its *** results also highlighted the importance of careful selection of reinforcement particles to avoid detrimental effects on the fracture behavior of the material.

关键词： TiC particle Dual-phase structure TiC-reinforced dual-phase steel Tension Fracture behavior

A Non-Parametric Scheme for Identifying Data Characteristic Based on Curve Similarity Matching

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1424-1437页

作者： Quanbo Ge Yang Cheng Hong Li Ziyi ye yi Zhu Gang Yao School of Automation Nanjing University of Information Science&TechnologyJiangsu Provincial University Key Laboratory of Big Data Analysis and Intelligent SystemsNanjing University of Information Science&Technologyand the Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)Nanjing University of Information Science&TechnologyNanjing 210044China School of Department of Logistics Engineering Shanghai Maritime UniversityShanghai 201306China China Classification Society Nantong Office Nantong 226006China Chinese Flight Test Establishment Xi’an 710089China School of Mathematics Tsinghua UniversityBeijing 100084China School of Automation Nanjing University of Information Science&TechnologyNanjing 210044China Department of Logistics Engineering Shanghai Maritime UniversityShanghai 201306China IEEE

For accurately identifying the distribution charac-teristic of Gaussian-like noises in unmanned aerial vehicle(UAV)state estimation,this paper proposes a non-parametric scheme based on curve similarity *** the framework of the pro-posed scheme,a Parzen window(kernel density estimation,KDE)method on sliding window technology is applied for roughly esti-mating the sample probability density,a precise data probability density function(PDF)model is constructed with the least square method on K-fold cross validation,and the testing result based on evaluation method is obtained based on some data characteristic analyses of curve shape,abruptness and *** com-parison simulations with classical methods and UAV flight exper-iment shows that the proposed scheme has higher recognition accuracy than classical methods for some kinds of Gaussian-like data,which provides better reference for the design of Kalman filter(KF)in complex water environment.

关键词： Curve similarity matching Gaussian-like noise non-parametric scheme parzen window.

Deep decalcification of factory-provided freezing acidolysis solution to achieveα-high-strength gypsum

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Chinese Journal of Chemical Engineering 2024年第5期69卷 143-151页

作者： Wencai ye Yulu Li Yonggang Dong Lin Yang Yun yi Jianxin Cao School of Chemistry and Chemical Engineering Guizhou UniversityGuiyang 550025China Engineering Research Center of Efficient Utilization for Industrial Waste Guizhou UniversityGuiyang 550025China Key Laboratory of Guizhou Province for Green Chemical Industry and Clean Energy Technology Guizhou UniversityGuiyang 550025China

The freezing acidolysis solution of the nitric acid-phosphate fertilizer process has a high calcium content,which makes it difficult to produce fine phosphate and high water-soluble phosphate fertilizer ***,based on the potential crystallization principle of calcium sulfate in NH_(4)NO_(3)-H_(3)PO_(4)-H_(2)O,the deep decalcification(*** removal)technology to achieveα-high-strength gypsum originated from freezing acidolysis-solutions has been firstly proposed and ***,calcium can be removed from the factory-provided freezing acidolysis-solution by neutralizing it with ammonia,followed by the addition of ammonium sulfate *** a result,the formation of calcium sulfate in the reaction system undergoes the nucleation and growth of CaSO_(4)·2H_(2)O(DH),as well as its dissolution and crystallization into short columnarα-CaSO_(4)·0.5H_(2)O(α-HH).Remarkably,with the molar ratio of SO_(4)^(2-)/Ca^(2+)at 1.8,the degree of neutralization(NH_(3)/HNO_(3) molar ratio)at 1.7,the reaction temperature of 94℃,and the reaction time of 300 min,the decalcification rate can reach 86.89%,of which the high-strengthα-CaSO_(4)·0.5H_(2)O(α-HH)will be ***,the deep decalcification product meets the standards for the production of fine phosphates and highly water-soluble phosphate ***,the 2 h flexural strength ofα-HH is 5.3 MPa and the dry compressive strength is 36.8 MPa,which is up to the standard of commercialα-HH.

关键词： Nitrophosphate Ammonia neutralization Deep decalcification High-strengthα-hemihydrate gypsum Controlled crystallization at atmospheric pressure

Lithium Sulfur Batteries:Insights from Solvation Chemistry to Feasibility Designing Strategies for Practical Applications

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Energy & Environmental Materials 2024年第4期7卷 5-27页

作者： Jian Tan Longli Ma Yuan Wang Pengshu yi Chuming ye Zhan Fang Zhiheng Li Mingxin ye Jianfeng Shen Institute of Special Materials and Technology Fudan University Department of Materials Science Fudan University Department of Chemistry Fudan University

Rechargeable lithium-sulfur (Li-S) batteries,featuring high energy density,low cost,and environmental friendliness,have been dubbed as one of the most promising candidates to replace current commercial rechargeable Li-ion ***,their practical deployment has long been plagued by the infamous"shuttle effect"of soluble Li polysulfides (LiPSs) and the rampant growth of Li dendrites.

关键词： characterization tools design strategies Li–S batteries practical applications solvation chemistry