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第九届全国免疫学学术大会

作者： yi-peng sun Yuan-Yuan Cai Hong-Miao Li Sen-Miao Deng Rui-Xue Leng Hai-Feng Pan Department of Epidemiology and Biostatistics School of Public HealthAnhui Medical University Anhui provincial laboratory of population health & major disease screening and diagnosis Anhui Medical University

Background:Type 1 diabetes mellitus(T1DM)is associated with an increased cardiovascular(CV)morbidity and mortality as compared with the general *** disease is based on atherosclerosis(AS).And carotid inti-ma-media thickness(CIMT)level is the symbol of early atherosclerosis,it has been shown to be the marker of preclinical *** is widely used as a noninvasive method to detect the atherosclerosis and to forecast cardiovascular disease in patients with *** recent years,a great many of studies have been performed to compare the mean CIMT difference between patients with T1DM and healthy ***,these studies have shown inconsistent or even contradictory ***:To derive a more precise estimation of CIMT levels in patients with T1DM by ***:PubMed and Embase databases were searched to identify all available studies comparing CIMT levels between T1DM group and control ***-analysis was performed to compare the difference of overall mean CIMT levels between the two *** bias was evaluated by funnel plot,Begg’test and Egger’***-regression analysis was conducted to investigate the influential factors on CIMT *** meta-analysis was conducted by STATA 12.0 ***:738 articles were obtained after searching databases,47 studies were finally included in the *** heterogeneity was observed among these studies(Q=768.75,P<0.001,I2=94.0%).Compared with control group,T1DM group had significantly higher CIMT levels(standardized mean difference:1.01,95%CI:0.75-1.28;P<0.001).A likely source of heterogeneity was NOS scores and sample size ratio of patents and *** funnel plot did not show a skewed or asymmetrical shape,and the result of Begg’test and Egger’test was P=0.178 and P=***,it could be assumed that publication bias was not ***:T1DM patients have significantly increased CIMT levels compared

关键词： type 1 diabetes mellitus carotid intima-media thickness atherosclerosis meta-analysis

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Optimizing distribution of multiple tuned mass dampers for building structures with inverse element exchange method

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Earthquake Engineering and Engineering Vibration 2025年第1期24卷 187-199页

作者： peng-Tai Chan Department of Marine Environment and Engineering Sun Yat-sen University(NSYSU)Kaohsiung 804TaiwanChina

Multiple tuned mass dampers(MTMDs)reduce dynamic response with multiple specified frequencies of building *** optimization algorithms for placement design exist,though they rarely conform to code-based verification nor produce high quality solutions without high computational effort and high *** study proposes an inverse element exchange method(IEEM)with multi-level programming and compares it to a single tuned mass damper(STMD)and uniform distribution of multiple tuned mass dampers in the frequency and time domains.A ten-story shear building is used for the numerical case *** results show that the proposed method can offer improvement over the STMD,uniform distribution of multiple tuned mass dampers,and distribution optimized by genetic algorithms(GA)with regard to minimizing the interstory drift ratio(IDR)in both the frequency and time domains and the time consumption for optimization.

关键词： tuned mass damper multiple tuned mass damper optimal damper placement design transfer function

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Tailoring Cathode-Electrolyte Interface for High-Power and Stable Lithium-Sulfur Batteries

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Nano-Micro Letters 2025年第4期17卷 181-211页

作者： Mengting Liu Ling-Jiao Hu Zhao-Kun Guan Tian-Ling Chen Xin-Yu Zhang Shuai sun Ruoli Shi Panpan Jing peng-Fei Wang Center of Nanomaterials for Renewable Energy State Key Laboratory of Electrical Insulation and Power EquipmentSchool of Electrical EngineeringXi’an Jiaotong UniversityXi’an 710049People’s Republic of China Low-Dimensional Materials and Photo/Electrochemical Technology Lab School of Materials Science and EngineeringShaanxi Key Laboratory of Green Preparation and Functionalization for Inorganic MaterialsShaanxi University of Science&TechnologyXi’an 710021People’s Republic of China

Global interest in lithium-sulfur batteries as one of the most promising energy storage technologies has been sparked by their low sulfur cathode cost,high gravimetric,volumetric energy densities,abundant resources,and environmental ***,their practical application is significantly impeded by several serious issues that arise at the cathode-electrolyte interface,such as interface structure degradation including the uneven deposition of Li_(2)S,unstable cathode-electrolyte interphase(CEI)layer and intermediate polysulfide shuttle ***,an optimized cathode-electrolyte interface along with optimized electrodes is required for overall ***,we comprehensively outline the challenges and corresponding strategies,including electrolyte optimization to create a dense CEI layer,regulating the Li_(2)S deposition pattern,and inhibiting the shuttle effect with regard to the solid-liquid-solid pathway,the transformation from solid-liquid-solid to solid-solid pathway,and solid-solid pathway at the cathode-electrolyte *** order to spur more perceptive research and hasten the widespread use of lithium-sulfur batteries,viewpoints on designing a stable interface with a deep comprehension are also put forth.

关键词： Lithium-sulfur batteries Shuttle effect Cathode-electrolyte interface Structural enhancement Reaction pathway

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4-Nitrophenol at environmentally relevant concentrations mediates reproductive toxicity in Caenorhabditis elegans via metabolic disorders-induced estrogen signaling pathway

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Journal of Environmental Sciences 2025年第1期147卷 244-258页

作者： Jia Wang Jiechen yin Danhong peng Xiaoqian Zhang Zhouhong Shi Weixi Li yingchi Shi Mingjun sun Nan Jiang Beijing Cheng Xingchen Meng Ran Liu Key Laboratory of Environmental Medicine Engineering Ministry of EducationSchool of Public HealthSoutheast UniversityNanjing 210009China Department of Obstetrics and Gynecology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjing 210009China Department of Obstetrics and Gynecology The Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu SchoolNanjing Medical UniversitySuzhouJiangsu 215002China

4-Nitrophenol(4-NP),as a toxic and refractory pollutant,has generated significant concern due to its adverse ***,the potential toxic effects andmechanism remained *** this study,the reproduction,development,locomotion and reactive oxygen species(ROS)production of Caenorhabditis elegans were investigated to evaluate the 4-NP *** used metabolomics to assess the potential damage *** role of metabolites in mediating the relationship between 4-NP and phenotypes was examined by correlation and mediation analysis.4-NP(8 ng/L and 8μg/L)caused significant reduction of brood size,ovulation rate,total germ cells numbers,head thrashes and body bends,and an increase in ***,the oosperm numbers in uterus,body length and body width were decreased in 8μg/***,36 differential metabolites were enriched in the significant metabolic pathways,including lysine biosynthesis,β-alanine metabolism,tryptophan metabolism,pentose phosphate pathway,pentose and glucuronate interconversions,amino sugar and nucleotide sugar metabolism,starch and sucrose metabolism,galactose metabolism,propanoate metabolism,glycerolipid metabolism,and estrogen signaling *** mechanism of 4-NP toxicity was that oxidative stress caused by the perturbation of amino acid,which had effects on energy metabolism through disturbing carbohydrate and lipid metabolism,and finally affected the estrogen signaling pathway to exert toxic ***,correlation and mediation analysis showed glycerol-3P,glucosamine-6P,glucosamine-1P,UDP-galactose,L-aspartic acid,and uracilwere potential markers for the reproduction and glucose-1,6P2 for developmental *** results provided insight into the pathways involved in the toxic effects caused by 4-NP and developed potential biomarkers to evaluate 4-NP toxicity.

关键词： 4-Nitrophenol Caenorhabditis elegans Metabolomics Pathway analysis

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A bio-inspired optical imaging method for robotic perception in turbid water

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Science China(Technological Sciences) 2025年第1期68卷 75-77页

作者： Xudong sun Yafeng LI peng LIN Xiaodi SHANG Xianping FU School of Information Science and Technology Dalian Maritime UniversityDalian 116026China College of Computer Science and Technology Qingdao UniversityQingdao 266071China

In the realm of underwater robotics,optical imaging plays a pivotal role in many scientific *** to the effects of absorption and scattering,images captured in turbid water are severely ***,enhancing the quality of underwater optical images stands paramount in ensuring the continued advancement and efficacy of underwater robots across its multifarious applications.

关键词： underwater optical continued

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Wetland and habitat dynamics in the evolving landscape of the Middle Yangtze River Basin

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Journal of Geographical Sciences 2025年第1期35卷 88-111页

作者： YANG peng sun Kaiya ZHU Yanchao XIA Jun HUANG Heqing SONG Jingxia SHI Xiaorui LU Xixi Hubei Key Laboratory of Regional Ecology and Environmental Change School of Geography and Information EngineeringChina University of GeosciencesWuhan430074China State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhan430072China Department of Geography National University of Singapore10 Kent RidgeCrescent119260Singapore

Wetlands play a critical role in the global *** Middle Yangtze River Basin(MYRB),known for its abundant wetland resources,has experienced notable changes resulting from the complex interplay of environmental ***,we investigated the spatiotemporal characteristics of wetland ecological quality in the MYRB from 2001 to *** the random forest(RF)regression algorithm and patch-generated land-use simulation(PLUS)model,we forecasted variations in wetland habitat quality and their determinants under the Shared Socioeconomic Pathway-Representative Concentration Pathway(SSPRCP)framework from 2035 to *** main findings are as follows:(1)The RF algorithm was optimal for land-use and land-cover(LULC)classification in the MYRB from 2001 to 2020,when notable changes were observed in water bodies and ***,the forested area exhibited an increase and decrease of 3.9%and 1.2%under the SSP1-2.6 and SSP5-8.5 scenarios,respectively,whereas farmland exhibited a diminishing trend.(2)Wetlands were primarily concentrated in the central and eastern MYRB,with counties in the southwest exhibiting superior ecological-environmental quality from 2001 to ***,wetland coverage revealed significantly high level,significant changes,frequent but relatively minor changes under the SSP1-2.6,SSP2-4.5,and SSP 5-8.5 scenarios,respectively.(3)Regions with lower habitat quality were primarily concentrated in urbanized areas characterized by frequent human activities,indicating a clear degradation in habitat quality across different *** conclusion,we established a foundational framework for future investigations into the eco-hydrological processes and ecosystem quality of watersheds.

关键词： Middle Yangtze River Basin wetland environmental change habitat quality multiple scenarios

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Carbon Dots-Modified Hollow Mesoporous Photonic Crystal Materials for Sensitivityand Selectivity-Enhanced Sensing of Chloroform Vapor

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Nano-Micro Letters 2025年第4期17卷 381-398页

作者： Junchen Liu Ji Liu Zhipeng Li Liupeng Zhao Tianshuang Wang Xu Yan Fangmeng Liu Xiaomin Li Qin Li peng sun Geyu Lu Dongyuan Zhao State Laboratory On Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012People’s Republic of China Department of Chemistry and Laboratory of Advanced Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsState Key Laboratory of Molecular Engineering of PolymersCollaborative Innovation Center of Chemistry for Energy Materials(2011-iChEM)College of Chemistry and MaterialsFudan UniversityShanghaiPeople’s Republic of China School of Engineering and Built Environment Griffith UniversityNathanQLD 4111Australia

Chloroform and other volatile organic pollutants have garnered widespread attention from the public and researchers,because of their potential harm to the respiratory system,nervous system,skin,and ***,research on chloroform vapor sensing is still in its early stages,primarily due to the lack of specific recognition *** we report a mesoporous photonic crystal sensor incorporating carbon dots-based nanoreceptor(HMSS@CDs-PCs)for enhanced chloroform *** colloidal PC packed with hollow mesoporous silica spheres provides an interconnected ordered macro-meso-hierarchical porous structure,ideal for rapid gas sensing utilizing the photonic bandgap shift as the readout *** as-synthesized CDs with pyridinic-N-oxide functional groups adsorbed in the hollow mesoporous silica spheres are found to not only serve as the chloroform adsorption sites,but also a molecular glue that prevents crack formation in the colloidal *** sensitivity of HMSS@CDs-PCs sensor is 0.79 nm ppm^(-1)and an impressively low limit of detection is 3.22 ppm,which are the best reported values in fast-response chloroform vapor sensor without multi-signal *** positive response time is 7.5 s and the negative response time 9 ***,relatively stable sensing can be maintained within a relative humidity of 20%-85%RH and temperature of 25-55℃.This study demonstrates that HMSS@CDs-PCs sensors have practical application potential in indoor and outdoor chloroform vapor detection.

关键词： Carbon dots Photonic crystal sensors Sensitivity-enhanced sensing Selectivity-enhanced sensing Chloroform vapor sensing

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Application of the improved dung beetle optimizer,muti-head attention and hybrid deep learning algorithms to groundwater depth prediction in the Ningxia area,China

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 18-23页

作者： Jiarui Cai Bo sun Huijun Wang yi Zheng Siyu Zhou Huixin Li Yanyan Huang Peishu Zong Collaborative Innovation Center on forecast and Evaluation of Meteorological Disasters/Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment ChangeNanjing University of Information Science and TechnologyNanjingChina Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) ZhuhaiChina China Meteorological Administration Key Laboratory of Transportation MeteorologyNanjingChina Jiangsu Meteorological Observatory NanjingChina

Due to the lack of accurate data and complex parameterization,the prediction of groundwater depth is a chal-lenge for numerical *** learning can effectively solve this issue and has been proven useful in the prediction of groundwater depth in many *** this study,two new models are applied to the prediction of groundwater depth in the Ningxia area,*** two models combine the improved dung beetle optimizer(DBO)algorithm with two deep learning models:The Multi-head Attention-Convolution Neural Network-Long Short Term Memory networks(MH-CNN-LSTM)and the Multi-head Attention-Convolution Neural Network-Gated Recurrent Unit(MH-CNN-GRU).The models with DBO show better prediction performance,with larger R(correlation coefficient),RPD(residual prediction deviation),and lower RMSE(root-mean-square error).Com-pared with the models with the original DBO,the R and RPD of models with the improved DBO increase by over 1.5%,and the RMSE decreases by over 1.8%,indicating better prediction *** addition,compared with the multiple linear regression model,a traditional statistical model,deep learning models have better prediction performance.

关键词： Groundwater depth Multi-head attention Improved dung beetle optimizer CNN-LSTM CNN-GRU Ningxia

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Effect of microinjecting GABAA-receptor antagonist into the tuberomammillary nucleus on the sleep-wakefulness cycle after lesion of the ventrolateral preoptic area in rats

Effect of microinjecting GABAA-receptor antagonist into the ...

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中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Xin ZHANG,yi-Na sun,peng XIE,Xu-Guang YANG,yi-Ping HOU~* Department of Neuroscience and Anatomy,Histology and Embryology,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000

Objective Recent evidences have demonstrated that the interaction between GABAergic neurons in the ventrolateral preoptic area(VLPO) and histaminergic(HA) neurons in the tuberomammillary nucleus(TMn) plays a key role for regulating sleep-wakefulness ***,GABAergic neurons in TMn have not received much attention for their role in sleep-wakefulness *** aim of this study is to investigate the effect of GABAergic neurons in the TMn on sleep-wakefulness *** Male SD rats(250-300 g,n=15) were randomized into 3 groups:before lesion group (n=5),VLPO lesion group(n=5) and VLPO lesion plus bicuculline treated group(n=5).The 4 EEG screw electrodes were implanted into the skull under anesthesia with pentobarbital(35 mg/Kg,ip),and three flexible EMG wire electrodes were placed into the nechal *** free ends of the leads were soldered into a *** cannular for microinjection were implanted into the adjacent of TMn(Aβ-4.2 mm,ML±1.3 mm,DV-7.4 mm).All implantations were affixed to the skull with dental cement,except the area(0.5 cm) around the bregma filling with bone wax that was *** week after surgery,the sockets were connected via flexible recording cables to EEG polygraph,signals were digitized by CED Micro 1401 and computer running the Spike 2 recording system.A 24 h basic wake-sleep states in before lesion group were recorded and analyzed by manually scored in 30 s epochs on the digitized EEG/*** the 8th day,a fine glass micropipette(10-20 mm tip diameter) containing ibotenic acid solution for specific cell damage(10 nM/0.5μ,Sigma) was injected into the VLPO on each side after bone wax removed under *** week after the second surgery,rats of VLPO lesion group were recorded for sleep-wakefulness *** the 10th day after lesion of VLPO,bicuculline(10 nM/0.5μ),a GABA-receptor antagonist,was microinjected into the TMn and recorded sleep-wakefulness states for 24 ***(1) The ratio during 24 h of wakefulness(

关键词： GABAergic neurons GABAA-receptor antagonist histaminergic neuron neurotoxic lesion tuberomammillary nucles ventrolateral preoptic area

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Effect of order–disorder transition on thermodynamic and electronic properties of σ and χ phases in W–Re alloy: the first-principles calculation

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Tungsten 2025年第1期7卷 195-213页

作者： Zhi-peng Zhu Dian Jia William yi Wang Jun-Lei yin Xing-Yu Gao Shu-Feng Yang Hai-Feng Song Jin-Shan Li State Key Laboratory of Solidification Processing Northwestern Polytechnical University Laboratory of Computational Physics Institute of Applied Physics and Computational Mathematics School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

The Tungsten-Rhenium(W-Re) alloys,celebrated for their high melting point,strength at elevated temperatures,electrical resistivity,and radiation resistance,have been widely utilized in high-temperature components,aerospace,electronics,and nuclear *** constituents of the topologically close-packed(TCP) phases,the sigma phase(σ) and chi phase(χ) formed within W-Re alloys wield considerable influence on the mechanical properties and the stability of the *** calculations were utilized in the present work to explore the structural,thermodynamic,and electronic properties of both ordered and disordered configurations within the σ and χ phases,culminating in a systematic elucidation of the higher phase stability exhibited by the ordered *** is found that the bulk modulus of these two phases is directly proportional to the concentration of Re in the alloy,while the equilibrium volume is inversely *** thermodynamic parameters of the σ and χ phases are calculated via the mean-field potential *** similar trends observed in the isobaric heat capacity,enthalpy increment,and entropy change curves for these two phases suggest they possess comparable thermodynamic *** is noteworthy that the contribution of ionic vibrations predominantly affects the isobaric heat capacity,while the contribution of thermal electronic excitations increases linearly with *** the structure and thermodynamic properties of TCP phases in W-Re alloys at low temperatures has profound significance for optimizing material performance,microstructures features,establishing theoretical foundations,and predicting material behavior.

关键词： First-principles calculations Phase stability TCP phases Thermodynamic properties W–Re alloy

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