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Population-based survey of prevalence,causes,and risk factors for blindness and visual impairment in an aging Chinese metropolitan population

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International Journal of Ophthalmology(English edition) 2017年第1期10卷 140-147页

作者： Jian-Yan Hu Liang Yan Yong-Dong Chen Xin-Hua Du Ting-Ting Li De-An Liu Dong-Hong Xu yi-min Huang Qiang Wu Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233China Community Health Center Xietu StreetXuhui DistrictShanghai 200233China

AIM： To assess the prevalence, causes, and risk factors for blindness and visual impairment among elderly （〉60 years of age） Chinese people in a metropolitan area of Shanghai, China. METHODS： Random cluster sampling was conducted to identify participants among residents ≥60 years of age living in the Xietu Block, Xuhui District, Shanghai, China. Presenting visual acuity （PVA） and best-corrected visual acuity （BCVA） were checked by the Early Treatment Diabetic Retinopathy Study （ETDRS） visual chart. All eligible participants underwent a comprehensive eye examination. Blindness and visual impairment were defined according to World Health Organization （WHO） criteria. RESULTS： A total of 4190 persons （1688 men and 2502 women） participated in the study, and the response rate was 91.1%. Based on PVA, the prevalence of blindness was 1.1% and that of visual impairment was 7.6%. Based on BCVA, the prevalence of blindness and visual impairment decreased to 0.9% and 3.9%, respectively. Older （〉80 years of age） women, with low educational levels and smoking habits, exhibited a significantly greater chance for blindness and visual impairment than did those with high educational levels and no smoking habits （P〈0.05）. Based on PVA and BCVA, the main causes of blindness were cataract, myopic maculopathy, and age-related macular degeneration （AMD）. CONCLUSION： Our findings help to identify the population in need of intervention, to highlight the need for additional eye healthcare services in urban China.

关键词： blindness visual impairment prevalence riskfactor cross-sectional study

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袁枚与童钰交谊考辨

华南师范大学学报（社会科学版） 2007年第1期 91-98,103页

作者：韩益民华南师范大学历史文化学院广东广州510631

章学诚于《书坊刻诗话后》中,指袁枚《随园诗话》中所言与画家童钰的生死交谊为诬。然而章氏与袁枚不同,文集中除此之外,绝无提及童钰处;袁枚诗文则有多篇纪念童钰,感情深挚,细节分明,不似章氏于事情多推断、猜测之词。就交往而论,章氏... 详细信息

章学诚于《书坊刻诗话后》中,指袁枚《随园诗话》中所言与画家童钰的生死交谊为诬。然而章氏与袁枚不同,文集中除此之外,绝无提及童钰处;袁枚诗文则有多篇纪念童钰,感情深挚,细节分明,不似章氏于事情多推断、猜测之词。就交往而论,章氏与童钰为同乡,但生平绝少交集,其知童钰,惟赖史家邵晋涵;袁枚戚友多人与童钰交往密切,童钰去世前八年,且有信致袁枚。就性情、志趣论,章氏与自然、诗歌、绘画无缘,经世思想浓重,保守自大;袁、童则均爱梅、爱诗,性情恬淡、放达,可谓志趣相投。章氏因忌嫉敌视袁枚,指袁枚伪造故实,实则是他自己昧于事实而妄言。章氏力倡“史德”之说,此处可谓背道而驰。

关键词：袁枚童钰交谊章学诚

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基于统计学习理论的小波神经网络优化

系统仿真学报 2006年第7期18卷 1769-1772页

作者：黄敏崔宝同顾树生江南大学控制科学与工程研究中心江苏无锡214122 东北大学信息科学与工程学院辽宁沈阳110004

传统的离散仿射小波神经网络训练都是建立在大样本基础上的,当样本数量较少时,不能保证网络的泛化能力。在研究统计学理论的基础上,提出了以结构风险最小化为目标的训练方法。首先根据样本数据和小波基函数的时频局部化特性构造隐含层... 详细信息

传统的离散仿射小波神经网络训练都是建立在大样本基础上的,当样本数量较少时,不能保证网络的泛化能力。在研究统计学理论的基础上,提出了以结构风险最小化为目标的训练方法。首先根据样本数据和小波基函数的时频局部化特性构造隐含层函数集,并按照小波基函数的能量大小来建立函数嵌套结构,然后采用自适应正交最小二乘法来训练网络权值,保证训练的小波神经网络结构风险最小化。仿真表明该方法不仅具有较高的收敛速度,而且最大限度地保证了网络的泛化能力。

关键词：统计学习理论小波神经网络结构风险最小化自适应正交最小二乘法

Methological Quality of Systematic Reviews and Meta-Analyses on Acupuncture for Stroke: A Review of Review

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Chinese Journal of Integrative Medicine 2017年第11期23卷 871-877页

作者： CHEN Xin-lin MO Chuan-wei LU Li-ya GAO Ri-yang XU Qian WU min-feng ZHOU Qian-yi HU Yue ZHOU Xuan LI Xian-tao College of Basic Medical Science Guangzhou University of Chinese Medicine Public Health Institute of Health and Wellbeing University of Glasgow First Clinical College Guangzhou University of Chinese Medicine

Objective： To assess the methodological quality of systematic reviews and meta-analyses regarding acupuncture intervention for stroke and the primary studies within them. Methods： Two researchers searched Pub Med, Cumulative index to Nursing and Allied Health Literature, Embase, ISI Web of Knowledge, Cochrane, Allied and Complementary Medicine, Ovid Medline, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang and Traditional Chinese Medical Database to identify systematic reviews and meta-analyses about acupuncture for stroke published from the inception to December 2016. Review characteristics and the criteria for assessing the primary studies within reviews were extracted. The methodological quality of the reviews was assessed using adapted Oxman and Guyatt Scale. The methodological quality of primary studies was also assessed. Results： Thirty-two eligible reviews were identified, 15 in English and 17 in Chinese. The English reviews were scored higher than the Chinese reviews（P=0.025）, especially in criteria for avoiding bias and the scope of search. All reviews used the quality criteria to evaluate the methodological quality of primary studies, but some criteria were not comprehensive. The primary studies, in particular the Chinese reviews, had problems with randomization, allocation concealment, blinding, dropouts and withdrawals, intent-to-treat analysis and adverse events. Conclusions： Important methodological flaws were found in Chinese systematic reviews and primary studies. It was necessary to improve the methodological quality and reporting quality of both the systematic reviews published in China and primary studies on acupuncture for stroke.

关键词： systematic review meta-analyses stroke acupuncture review of review methodological quality

Quantitatively determine the dominant driving factors of the spatial–temporal changes of vegetation NPP in the Hengduan Mountain area during 2000-2015

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Journal of Mountain Science 2021年第2期18卷 427-445页

作者： CHEN Shu-ting GUO Bing ZHANG Rui ZANG Wen-qian WEI cui-xia WU Hong-wei YANG Xiao ZHEN Xiao-yan LI Xing ZHANG Da-fu HAN Bao-min ZHANG Hai-ling School of Civil Architectural Engineering Shandong University of TechnologyZibo 255000China State Key Laboratory of Resources and Environmental Information System Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China Key Laboratory of Land use Ministry of Natural ResourcesChina Land Survey and Planning InstituteBeijing 100035China Key Laboratory for Digital Land and Resources of Jiangxi Province East China University of TechnologyNanchang 330013China Key Laboratory of National Geographic Census and Monitoring Ministry of Natural ResourcesWuhan 430079China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100101China Key Laboratory of UrbanLand Resources Monitoring and Simulation Ministry of Natural ResourcesShenzhen 518000China Key Laboratory of Meteorology and Ecological Environment of Hebei Province Shijiazhuang 050021China Land Satellite Remote Sensing Application Center Ministry of Natural ResourcesBeijing 100048China College of Geological Engineering and Geomatics Chang'an UniversityXi'an 710054China

The Hengduan mountain area,located in the upper reaches of the Yangtze River of China,is an important ecological barrier that significantly impacts the climate and ecological environment of the surrounding region and western China as a *** paper introduces the gravity center model used to analyze the spatial-temporal variation patterns of vegetation Net Primary Productivity(NPP)from 2000 to 2015,which were determined by the use of MOD17 A3 NPP ***,the dominant driving factors of the spatial–temporal changes of vegetation NPP of the Hengduan Mountain area were quantitatively determined with a geographical detector over *** results revealed that:(1)From 2000 to 2015,there was an increasing trend of vegetation NPP in the Hengduan mountain *** the whole study region,the vegetation NPP with a mean value of 611.37 gC·m^(-2)·a^(-1) indicated a decreasing trend from southeast to northwest in terms of spatial distribution.(2)The gravity centers of vegetation NPP in 2000-2015 were mainly concentrated in Zhongdian *** the study period,the gravity center of vegetation NPP moved northward,which indicated that the increment and increasing rate of vegetation NPP in the northern parts were greater than that of the southern areas.(3)The vegetation NPP showed a moderately positive correlation with temperature,accumulated temperature(>10℃),and sunshine,while there was an overall negative relationship between NPP and precipitation.(4)The dominant factors and interactive dominant factors changed in different subregions over different segments of the study *** dominant factors of most sub-regions in Hengduan mountain were natural factors,and the climate change factors played an increasingly greater role over the 16 years of the study period.

关键词： Vegetation NPP Spatial-temporal distribution Driving factors Geographic detector Land use change

Seroprevalence and evolutionary dynamics of genotype 4 hepatitis E virus in Shandong Province,China

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World Journal of Gastroenterology 2014年第24期20卷 7955-7963页

作者： Dong Yang Mei Jiang min Jin Zhi-Gang Qiu Zhi-Qiang Shen Wei-Hong cui Da-Ning Wang Lian-Feng Gong Bo Li Xin-Wei Wang Jun-Wen Li Department of Environment and Health Tianjin Institute of Health and Environmental Medicine Key Laboratory of Risk Assessment and Control for Environment and Food Safety Yantai Center for Disease Control and Prevention

AIM: To investigate the seroprevalence and evolutionary dynamics of hepatitis E virus (HEV) and assess the ancestor of HEVs in China’s Shandong Province.

关键词： Hepatitis E virus Zoonotic Cross-species transmission Trans-regional transmission Evolutionary dynamics

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产业参与、平台协同与精准扶贫

华南农业大学学报（社会科学版） 2018年第6期17卷 12-21页

作者：易法敏华南农业大学经济管理学院广东广州510642

在信息技术赋能下,电商平台能够实现商业模式创新,即普遍连接、互动参与和服务创新;在不发达地区,这种模式表现为促进平台广泛连接农户、推动贫困群体及社会力量多方参与、形成服务创新型生态系统。以平台为核心的农村电商生态系统在吸... 详细信息

在信息技术赋能下,电商平台能够实现商业模式创新,即普遍连接、互动参与和服务创新;在不发达地区,这种模式表现为促进平台广泛连接农户、推动贫困群体及社会力量多方参与、形成服务创新型生态系统。以平台为核心的农村电商生态系统在吸引众多主体参与的前提下,以扶持特色产业发展为核心,协调和带动了贫困地区的可持续扶贫。结合京东"跑步鸡"案例,提出电商扶贫的基本模式:在扶贫生态系统中,平台通过资源整合,发展可持续的特色化产业,并以此构建扶贫服务支点;农户在平台协同下,通过参与产业链获取市场机会以及直接参与生态系统的价值分配,进而获得知识与技能,积累持续发展能力。

关键词：电商平台农村电商生态系统扶贫生态系统特色产业参与式扶贫

Down-regulated γ-catenin expression is associated with tumor aggressiveness in esophageal cancer

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World Journal of Gastroenterology 2014年第19期20卷 5839-5848页

作者： Wang-Kai Fang Lian-Di Liao Wei Gu Bo Chen Zhi-Yong Wu Jian-yi Wu Jian Shen Li-Yan Xu En-min Li Department of Biochemistry and Molecular Biology The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan AreaShantou University Medical College Institute of Oncologic Pathology Shantou University Medical College Department of Oncology Surgery Affiliated Shantou Hospital of Sun Yat-sen University

AIM: To evaluate the significance of γ-catenin in clinical pathology, cellular function and signaling mechanism in esophageal squamous cell carcinoma (ESCC).

关键词： γ -catenin Esophageal squamous cell carcinoma Independent prognostic factor Cell-cell adhesion Cell migration

广陈皮标准汤剂HPLC指纹图谱的构建及其与广陈皮药材、饮片的质量相关性研究

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中南药学 2024年第10期22卷 2569-2575页

作者：罗嘉敏赖恩平宁金容刘怡琪张钰李佩佩胡云广罗文汇郑国栋韦敏燕广州医科大学药学院广州511436 广东一方制药有限公司医学部广东佛山528244

目的构建广陈皮标准汤剂HPLC指纹图谱,并考察其与广陈皮药材、饮片的质量相关性。方法通过高效液相色谱法对广陈皮药材、饮片及标准汤剂各15批进行分析,采用中药色谱指纹图谱相似度评价系统(2012版)进行其指纹图谱的构建及相似度分析,... 详细信息

目的构建广陈皮标准汤剂HPLC指纹图谱,并考察其与广陈皮药材、饮片的质量相关性。方法通过高效液相色谱法对广陈皮药材、饮片及标准汤剂各15批进行分析,采用中药色谱指纹图谱相似度评价系统(2012版)进行其指纹图谱的构建及相似度分析,并对三者的4种有效成分橙皮苷、川陈皮素、橘皮素和D-柠檬烯进行定量测定。结果建立了广陈皮药材、饮片及标准汤剂的HPLC指纹图谱,分别确定了18、18和16个共有峰。与广陈皮药材对照指纹图谱比较,饮片对照指纹图谱的相似度为0.994,标准汤剂对照指纹图谱的相似度为0.833。广陈皮标准汤剂的出膏率均值为(43.2±0.1)%,橙皮苷、川陈皮素、橘皮素和D-柠檬烯的转移率平均值分别为(19.3±4.9)%、(25.3±4.0)%、(16.6±2.5)%、(2.2±2.2)%。结论建立的指纹图谱反映出广陈皮药材、饮片及标准汤剂的化学成分基本一致。经分析比较,标准汤剂中橙皮苷、川陈皮素和橘皮素等成分与药材、饮片具有良好的正相关性。本研究可为广陈皮标准汤剂及配方颗粒等相关制剂的生产制备、质量控制提供参考。

关键词：广陈皮标准汤剂高效液相色谱法指纹图谱