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An Effective Threat Detection Framework for Advanced Persistent Cyberattacks

Computers, Materials & Continua 2023年第5期75卷 4231-4253页

作者： So-Eun Jeon Sun-Jin Lee Eun-Young Lee Yeon-Ji Lee jung-Hwa Ryu jung-Hyun Moon Sun-Min yi Il-Gu Lee Department of Future Convergence Technology Engineering Sungshin Women’s UniversitySeoul02844Korea Department of Convergence Security Engineering Sungshin Women’s UniversitySeoul02844Korea

Recently,with the normalization of non-face-to-face online environments in response to the COVID-19 pandemic,the possibility of cyberattacks through endpoints has *** endpoint devices are managed meticulously to prevent cyberattacks and ensure timely responses to potential security *** particular,because telecommuting,telemedicine,and teleeducation are implemented in uncontrolled environments,attackers typically target vulnerable endpoints to acquire administrator rights or steal authentication information,and reports of endpoint attacks have been increasing *** persistent threats(APTs)using various novel variant malicious codes are a form of a sophisticated ***,conventional commercial antivirus and anti-malware systems that use signature-based attack detectionmethods cannot satisfactorily respond to such *** this paper,we propose a method that expands the detection coverage inAPT attack *** this model,an open-source threat detector and log collector are used synergistically to improve threat detection *** the scope of attack log collection through interworking between highly accessible open-source tools can efficiently increase the detection coverage of tactics and techniques used to deal with APT attacks,as defined by MITRE Adversarial Tactics,Techniques,and Common Knowledge(ATT&CK).We implemented an attack environment using an APT attack scenario emulator called Carbanak and analyzed the detection coverage of Google Rapid Response(GRR),an open-source threat detection tool,and Graylog,an open-source log *** proposed method expanded the detection coverage against MITRE ATT&CK by approximately 11%compared with that conventional methods.

关键词： Advanced persistent threat cybersecurity endpoint security MITRE ATT&CK open-source threat detector threat log collector

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Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral

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International Journal of Oral Science 2023年第4期15卷 676-690页

作者： Hyun-yi Kim Victoria Cooley Eun-jung Kim Shujin Li Jong-Min Lee Dina Sheyfer Wenjun Liu Ophir D.Klein Derk Joester Han-Sung jung NGeneS Inc. Ansan-siGyeonggi-doKorea Department of Materials Science and Engineering Northwestern UniversityEvanstonILUSA X-ray Science Division Advanced Photon SourceArgonne National LaboratoryLemontILUSA Division in Anatomy and Developmental Biology Department of Oral BiologyOral Science Research CenterBK21 FOUR ProjectYonsei University College of DentistrySeoulKorea Department of Orofacial Sciences and Program in Craniofacial Biology University of CaliforniaSan FranciscoCAUSA Department of Pediatrics Cedars-Sinai Guerin Children’sLos AngelesCAUSA

Ameloblasts are specialized cells derived from the dental epithelium that produce enamel,a hierarchically structured tissue comprised of highly elongated hydroxylapatite(OHAp)*** unique function of the epithelial cells synthesizing crystallites and assembling them in a mechanically robust structure is not fully elucidated yet,partly due to limitations with in vitro experimental ***,we demonstrate the ability to generate mineralizing dental epithelial organoids(DEOs)from adult dental epithelial stem cells(aDESCs)isolated from mouse incisor *** expressed ameloblast markers,could be maintained for more than five months(11 passages)in vitro in media containing modulators of Wnt,Egf,Bmp,Fgf and Notch signaling pathways,and were amenable to *** transplanted underneath murine kidney capsules,organoids produced OHAp crystallites similar in composition,size,and shape to mineralized dental tissues,including some enamel-like elongated *** are thus a powerful in vitro model to study mineralization process by dental epithelium,which can pave the way to understanding amelogenesis and developing regenerative therapy of enamel.

关键词： epithelium maintained specialized

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Impact of non-Hermitian mode interaction on inter-cavity light transfer

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Photonics Research 2022年第5期10卷 1232-1237页

作者： HYEON-HYE YU SUNJAE GWAK JINHYEOK RYU HYUNDONG KIM JI-HWAN KIM jung WAN RYU CHIL-MIN KIM CHANG HWAN yi Department of Emerging Materials Science DGISTDaegu 42988Republic of Korea Center for Theoretical Physics of Complex Systems Institute for Basic Science(IBS)Daejeon 34126Republic of Korea

Understanding inter-site mutual mode interaction in coupled physical systems is essential to comprehend large compound systems,as this local interaction determines the successive multiple inter-site energy transfer *** the present study,we demonstrate that only the non-Hermitian coupling can correctly account for the light transfer between two coupled optical *** also reveal that the non-Hermitian coupling effect becomes crucial as the system dimension *** results provide important insight for handling general-coupled devices in the subwavelength regime.

关键词： interaction transfer coupling

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甘草抗肿瘤研究进展及发展趋势可视化分析

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中国药师 2024年第1期27卷 76-84页

作者：殷亭湄杨必乾付晓艳邓毅甘肃中医药大学药学院兰州730000 甘肃省中药药理与毒理学重点实验室兰州730000

目的利用CiteSpace知识图谱分析甘草抗肿瘤的中英文文献,探索其研究现状、热点及趋势。方法运用CiteSpace 6.2.R4软件对CNKI和Web of Science中收录的2002年1月至2023年9月甘草抗肿瘤的中英文相关文献,从发文量、作者、机构、期刊、基... 详细信息

目的利用CiteSpace知识图谱分析甘草抗肿瘤的中英文文献,探索其研究现状、热点及趋势。方法运用CiteSpace 6.2.R4软件对CNKI和Web of Science中收录的2002年1月至2023年9月甘草抗肿瘤的中英文相关文献,从发文量、作者、机构、期刊、基金资助、关键词等研究主题进行可视化分析。结果共纳入397篇中文文献,172篇英文文献。中英文文献作者分析表明郑秋生和jung分别为甘草抗肿瘤中文和英文发文量最多的作者;北京中医药大学和翰林大学分别为中文和英文发文量最多的机构,英文文献中研究机构之间的合作相对较多;中英文关键词分析显示甘草抗肿瘤研究主要集中在乳腺癌、甘草及其活性成分、分子机制等方面。聚类分析显示,研究集中在甘草活性成分及临床应用,中医治法理论及复方常用药物,甘草抗肿瘤的实验研究及作用机制,甘草防治化疗药物引起的肾毒性等毒副作用的作用机制研究上。结论甘草抗肿瘤的机制探讨以及甘草与天然产物联合用药可能为今后的研究热点。

关键词：甘草肿瘤 CiteSpace 研究热点趋势研究进展

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Parameterization of below-cloud scavenging for polydisperse fine mode aerosols as a function of rain intensity

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Journal of Environmental Sciences 2023年第10期132卷 43-55页

作者： Chang Hoon jung Hyung-Min Lee Dasom Park Young Jun Yoon Yongjoo Choi Junshik Um Seoung Soo Lee Ji yi Lee Yong Pyo Kim Department of Health Management Kyungin Women’s UniversityIncheon 21041Korea Department of Environmental Science and Engineering Ewha Woman’s UniversitySeoulKorea Department of Environmental Engineering Konkuk UniversitySeoulKorea Korea Polar Research Institute IncheonKorea Department of Environment Hankuk University of Foreign StudiesYonginKorea Department of Atmospheric Sciences Pusan National UniversityBusanKorea Earth System Science Interdisciplinary Center University of MarylandCollege ParkMDUSA Research Center for Climate Sciences Pusan National UniversityBusanKorea Department of Chemical Engineering and Materials Science Ewha Womans UniversitySeoulKorea

The below-cloud aerosol scavenging process by precipitation is one of the most important mechanisms to remove aerosols from the *** to its complexity and dependence on both aerosol and raindrop sizes,wet scavenging process has been poorly treated,especially during the removal of fine *** makes the numerical simulation of below-cloud scavenging in large-scale aerosolmodels *** consider the slip effects of submicron particles,a simplified expression for the diffusion scavenging was developed by approximating the Cunningham slip correction *** derived analytic solution was parameterized as a simple power function of rain intensity under the assumption of the lognormal size distribution of *** resultant approximated expression was compared to the observed data and the results of previous studies including a 3D atmospheric chemical transport model *** with the default GEOS-Chem coefficient of 0.00106R0.61 and the observation-based coefficient of 0.0144R0.9268,the coefficient of a and b in∧m=aRb spread in the range of 0.0002-0.1959 for a and 0.3261-0.525 for b over a size distribution of GSD of 1.3–2.5 and a geometric mean diameter of 0.01-2.5μ***,this study showed that the scavenging coefficient varies widely by orders of magnitude according to the size distribution of particles and rain *** study also demonstrated that the obtained simplified expression could consider the theoretical approach of aerosol *** proposed analytic approach showed that results can be effectively applied for reduced computational burden in atmospheric modeling.

关键词： Below-cloud scavenging Polydisperse aerosol Parameterization Cunningham correction factor Scavenging coefficient

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EchoNavigator virtual marker and Agilis NxT steerable introducer facilitate transseptal transcatheter closure of mitral paravalvular leak

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World Journal of Clinical Cases 2022年第13期10卷 4236-4241页

作者： jung-Cheng Hsu Chong-Sun Khoi Shan-Hui Huang yi-Yao Chang Shu-Lu Chen Yen-Wen Wu Division of Cardiology Department of MedicineFar Eastern Memorial HospitalNew Taipei City 220216Taiwan General Education Center Lunghwa University of Science and TechnologyTaoyuan City 333026Taiwan Department of Anesthesiology Far Eastern Memorial HospitalNew Taipei City 220216Taiwan

BACKGROUND Paravalvular leak(PVL),also known as paravalvular prosthetic regurgitation,is not a rare complication after surgical valve replacement,and it may cause varying degrees of heart *** transcatheter closure of PVL is technically demanding and *** SUMMARY A 68-year-old man presented with degenerative mitral regurgitation with heart failure,New York Heart Association functional class *** received bioprosthetic mitral valve replacement in December *** was noted at the location of the aorto-mitral curtain in transesophageal echocardiography without signs of endocarditis or dehiscence of the bioprosthetic *** transcatheter closure of the mitral PVL was performed efficiently using the EchoNavigator virtual marker and Agilis NxT steerable *** This case highlights that the EchoNavigator virtual marker and Agilis NxT steerable introducer can facilitate transseptal transcatheter closure of mitral PVL by reducing the procedure time and contrast media.

关键词： Paravalvular leak Paravalvular prosthetic regurgitation EchoNavigator Steerable introducer Case report

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Enhanced thermoelectric properties of NbCoSn half-Heuslers through in-situ nanocrystallization of amorphous precursors during the consolidation process

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Journal of Materials Science & Technology 2023年第34期165卷 39-48页

作者： Chanwon jung Kyuseon Jang Hail Park Jeongin Jang Hanhwi Jang Byungchul Kang Kitae Park Siyuan Zhang Ruben Bueno Villoro SuDong Park Ho Jin Ryu Yeon Sik jung Min-Wook Oh Christina Scheu Seong-Hoon yi Pyuck-Pa Choi Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Max-Planck-Institut für Eisenforschung GmbH Düsseldorf 40237Germany Electrical Materials Research Division Energy Conversion Research CenterKorea Electrotechnology Research Institute(KERI)Changwon 51543Republic of Korea Department of Materials Science and Metallurgical Engineering Kyungpook National University80 DaehakroDaegu 41566Republic of Korea Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Department of Materials Science and Engineering Hanbat National University125 Dongseodae-roYuseong-guDaejeon 34158Republic of Korea

Tailoring nanostructures is a general approach used to obtain enhanced thermoelectric properties for halfHeusler compounds because the wide areas of grain and phase boundaries could be scattering centers that lower lattice thermal ***,a common fabrication method based on the sintering of crystalline precursors crushed from as-cast alloy ingots has limitations in obtaining a homogeneous microstructure without microsized impurity phases,owing to residual elemental segregation from *** this study,we used amorphous NbCoSn alloys as a precursor for the sintered specimen to obtain a homogeneous NbCoSn bulk specimen without microsized impurity phases and segregation,which led to the enhanced Seebeck coefficient due to the high purity of the half-Heusler phase after ***,superplasticity originating from amorphous features enabled the powders to be largely deformed during the sintering process,even at a low sintering temperature(953 K).This resulted in less oxidation at both,the grain boundary and the interior,as the O diffusion pathway was blocked during the sintering *** a result,the NbCoSn0.95Sb0.05 specimen using an amorphous precursor exhibited an enhanced zT of 0.7,due to the increase in the power factor and a decrease in lattice thermal conductivity compared to the specimen using a crystalline precursor.

关键词： Half-Heusler compounds Amorphous Superplasticity Segregation Atom probe tomography

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Use of sewage sludge biochar as a catalyst in production of biodiesel through thermally induced transesterification

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Biochar 2022年第1期4卷 74-88页

作者： Sungyup jung Minyoung Kim Yong-Hyun Kim Kun-yi Andrew Lin Wei-Hsin Chen yiu Fai Tsang Eilhann E.Kwon Department of Environmental Engineering Kyungpook National UniversityDaegu 41566Republic of Korea. Department of Earth Resources and Environmental Engineering Hanyang UniversitySeoul 04763Republic of Korea Department of Civil EnvironmentalResources and Energy EngineeringJeonbuk National UniversityJeollabukdoJeonju 54896Republic of Korea Department of Environmental Engineering and Innovation and Development Center of Sustainable Agriculture National Chung Hsing University250 Kuo-Kuang RoadTaichungTaiwanChina Department of Aeronautics and Astronautics National Cheng Kung UniversityTainan 701TaiwanChina Research Center for Smart Sustainable Circular Economy Tunghai UniversityTaichung 407TaiwanChina Department of Mechanical Engineering National Chin-Yi University of TechnologyTaichung 411TaiwanChina Department of Scienceand Environmental Studies The Education University of Hong KongTai PoNew Territories999077 Hong KongHong Kong

Sewage sludge(SS)is a residual/semi-solid material produced from industrial and municipal wastewater treatment *** contains a high content of lipids and earth alkaline metals that can be used as catalysts for various chemical applications;however,its valorization has rarely been the focus of *** study demonstrates that SS could be a promising raw material for biodiesel production and a biochar catalyst to promote the reaction kinetics of *** induced transesterification of the SS extract(SSE)was performed in comparison with the conventional homogeneous *** biochar was fabricated via *** highest yield(33.5 wt.%per SSE)of biodiesel production was achieved in 1 min of reaction at 305℃via thermally induced transesterification in the presence of SS biochar,while the yield of biodiesel from(trans)esterification with 5 wt.%H_(2)SO_(4)was less than 1%even after 24 *** reaction kinetics(<1 min)of thermally induced transesterification was extraordinarily faster than that of conventional transesterification(3-24 h).The porous structure and high content of alkaline species in the SS biochar expedited the reaction ***,the integrated/hybridized process for thermally induced transesterification and pyrolysis of the solid residue of SS was experimentally proved for the valorization of SS in this *** that SS is being disposed of as a waste material and generates toxic chemicals in the environment,its valorization into value-added biodiesel and a catalyst could be an environmentally benign and sustainable technique.

关键词： Circular economy Waste-to-energy Biochar catalyst Biodiesel Wastewater treatment

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Study on Extended Gate Field Effect Transistor with Nano-TiO-2 Sensing Membrane by Sol-Gel Method

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稀有金属材料与工程 2006年第A3期35卷 252-253页

作者： yi-Hung Liao jung-Chuan Chou Graduate School of Engineering Science and Technology National Yunlin University of Science and TechnologyDouliouTaiwan 640China

The nano-titanium dioxide (nano-TiO_2) sensing membrane,fabricated by sol-gel technology,was used as the pH-sensing layer of the extended gate field effect transistor (EGFET) *** objective of this research is the preparation of titanium dioxide materials by sol-gel method using Ti(OBu)_4 as the *** this study,we fabricated a nano-titanium dioxide sensing layer on the ITO glass by dip *** order to examine the sensitivity of the nano-TiO_2 films applied to the EGFET devices,we adopted the ITO glass as substrate,and measured theⅠ_(DS)-Ⅴ_G curves of the nano-titanium dioxide separative structure EGFET device in the pH buffer solutions that have different pH values by the Keithley 236 *** the experimental results,we can obtain the pH sensitivities of the EGFET with nano-TiO_2 sensing membrane prepared by sol-gel method,which is 59.86mV/pH from pH 1 to pH 9.

关键词： extended gate field effect transistor(EGFET) sol-gel nano-TiO2 sensing membrane buffer solution

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Study on the Carbon Nanotube Separative Structure for the Extended Gate H^+-Ion Sensitive Field Effect Transistor

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稀有金属材料与工程 2006年第A3期35卷 225-227页

作者： yi-Hung Liao jung-Chuan Chou Graduate School of Engineering Science and Technology National Yunlin University of Science and TechnologyDouliouYunlinTaiwan 640China

We use the carbon nanotube (CNT) as the material of the pH sensing layer of the separative structure for the extended gate H^+-ion sensitive field effect transistor (EGFET) *** CNT paste was prepared with CNT powder,Ag powder,silicagel,the di-n-butyl phthalate and the toluene solvents by appropriate ratio,then immobilized on the silicon substrate to form the carbon nanotube sensing *** measured theⅠ_(DS)-Ⅴ_G curves of the carbon nanotube separative structure EGFET device in the different pH buffer solutions by the Keithley 236Ⅰ-Ⅴmeasurement *** to the experimental results,we can obtain the pH sensitivities of the carbon nanotube separative structure EGFET device,which is 62.54mV/pH from pH1 to pH13.

关键词： carbon nanotube extended gate field effect transistor pH sensitivity buffer solution

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