检索结果-南通市图书馆

Tungsten 2024年第4期6卷 657-662页

作者： Xin-yi Zhang Igor V.Zatovsky jun-Ming cao Xing-Long Wu Faculty of Chemistry Northeast Normal UniversityChangchun130024China F.D.Ovcharenko Institute of Biocolloidal Chemistry NAS UkraineKiev03142Ukraine MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityChangchun130024China

Acid hydrogen evolution reaction(HER)is a critical energy conversion process,which is significantly important in hydrogen energy manufacturing and storage[1].Although the performance of noble metal platinum(Pt)-based catalysts in acidic HER is well known,the challenges are high cost,limited reserves,poor stability,and susceptibility to toxic substances[2].Therefore,it is urgent to design and manufacture acidic HER catalysts with high reactivity,high stability,and low cost.

关键词： stability cluster porous

CD176 single-chain variable antibody fragment inhibits the adhesion of cancer cells to endothelial cells and hepatocytes

在线全文

学校读者我要写书评

暂无评论

Frontiers of Medicine 2016年第2期10卷 204-211页

作者： Jiangnan Liu Bin yi Zhe Zhang yi cao Laboratory of Molecular and Experimental Pathology Kunming Institute of Zoology Chinese Academy of Sciences Kunming 650223 China Kunming College of Life Science University of Chinese Academy of Sciences Kunming 650223 China

CD176 （Thomsen-Friedenreich antigen） is a tumor-associated carbohydrate epitope （glycotope） functionally involved in blood spread and fiver metastasis of cancer cells by mediating the adhesion of cancer cells to endothelial cells and hepatocytes, respectively. CD176 could be a promising target for antitumor immunotherapy. We applied B lymphocytes obtained from mice immunized with CD176 antigen and constructed a phage display library. A positive clone of CD176 single-chain variable antibody fragment （scFv） was successfully screened from this library. The CD176 scFv was expressed in Escherichia coli and purified. The purified scFv can bind to the natural CD176 expressed on the surface of cancer cells. Furthermore, the CD176 scFv inhibits the adhesion of CD176＋ cancer cells to endothelial cells and hepatocytes. This CD176 scFv provides a basis for future development of recombinant CD176-specific antibodies that can be used in therapeutic application.

关键词： CD 176 Thomsen-Friedenreich antigen scFv cancer therapy adhesion metastasis

Water science on the molecular scale: new insights into the characteristics of water

在线全文

学校读者我要写书评

暂无评论

National Science Review 2014年第2期1卷 179-181页

作者： jun Hu Zexian cao Shanghai Institute of Applied Physics Chinese Academy of Sciences Institute of Physics Chinese Academy of Sciences

The highest good is like that of *** goodness of water is that it beneits all the creatures;yet itself does not scramble,but is content with the places that all men *** is this that makes water so near to Tao.—Tao Te ChingWATER IS IMPORTANT Water is a basic component of human existence,and people and ecosystems depend on *** is one of the most fundamental requirements for the survival of

关键词： new insights into the characteristics of water Water science on the molecular scale

The Early Permian Woniusi Flood Basalts from the Baoshan Terrane, SW China: Petrogenesis and Geodynamic Implications

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2020年第6期94卷 2091-2114页

作者： cao jun ZHANG Gaizhi WANG Xuan CHEN jun State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China Shandong Key Laboratory of Depositional Mineralization&Sedimentary Minerals Shandong University of Science and TechnologyQingdaoShandong 266590China School of Earth Sciences East China University of TechnologyNanchang 330013China State Key Laboratory of Isotope Geochemistry Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China

The Woniusi flood basalts from the Baoshan terrane,SW China,represent a significant eruption of volcanic rocks which were linked to the Late Paleozoic rifting of the Cimmeria from the northern margin of East ***,the precise mechanism for the formation and propagation of the rifting is still in *** we report 40 Ar/39 Ar dating,whole-rock geochemistry,and Sr-Nd-Pb isotopes for the Woniusi basalts from the Baoshan terrane of SW China,with the aim of assessing if a mantle plume was related to the formation of the continent Cimmeria.40 Ar/39 Ar dating of the Woniusi basalts yielded ages of 279.3±1.1 Ma and 273.9±1.5 Ma,indicating they were emplaced during the Early ***-rock geochemistry shows that these basalts have subalkaline tholeiitic affinity,low Ti O2(1.2-2.2 wt%),and fractionated chondrite-normalized LREE and nearly flat HREE patterns[(La/Yb)N=2.86-5.77;(Dy/Yb)N=1.21-1.49]with noticeable negative Nb and Ta anomalies on the primitive mantle-normalized trace element ***ε(Nd)(t)values(-4.76 to+0.92)and high(206 Pb/204 Pb)i(18.40-18.66)along with partial melt modeling indicates that the basalts were likely derived from a sub-continental lithospheric mantle(SCLM)source metasomatized by subduction-related *** the basis of a similar emplacement age to the Panjal basalts and Qiangtang mafic dykes and flood basalts in the Himalayas,combined with a tectonic reconstruction of Gondwana in the Early Permian,we propose that the large-scale eruption of these basalts and dykes was related to an Early Permian mantle plume that possibly initiated the rifting on the northern margin of East Gondwana.

关键词： geochemistry flood basalts Early Permian Baoshan Gondwana

Tenofovir rescue therapy in pregnant females with chronic hepatitis B

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第8期21卷 2504-2509页

作者： Yu-Hong Hu Min Liu Wei yi Yan-jun cao Hao-Dong Cai Department of Hepatology Beijing Ditan Hospital Capital Medical University

AIM:To evaluate the safety and efficacy of tenofovir monotherapy in pregnant females resistant to lamivudine or *** effect of tenofovir on the fetus was also ***:The clinical data of 17 females were reviewed in this *** events and pregnancy outcomes from January 1,2011 to june 30,2013 were evaluated in the Department of Gynecology and Obstetrics of BeijingDitan Hospital,Capital Medical University,Beijing,*** pregnant females developed lamivudine(LAM)-or telbivudine(Ld T)-resistant chronic hepatitis B and received tenofovir(TDF)therapy(300 mg/d),and its curative effect,maternal and perinatal adverse events,fetal growth and development,and neonatal prognosis were ***:The median hepatitis B virus(HBV)DNA level in the pregnant females with LAM or Ld T resistance was 5.9(range,4.2-7.2)log10 copies/m L before the initiation of *** of these females had abnormal alanine aminotransferase(ALT)*** patients were treated with TDF for a median of 24 wk(range,12-40 wk).Fourteen females(82.4%)had an HBV DNA level of<500 copies/m L at the time of *** decrease was statistically significant(P<0.0001).Serum ALT levels were normalized in all subjects with an elevated serum ALT level at baseline(P=0.0003).There were no significant changes in serum creatinine and phosphorus levels during TDF *** addition,no adverse events related to TDF treatment were *** females delivered 17 live infants,and all infants had good Apgar *** mean birth weight was 3226.5±331.7 g,and the mean length at birth was 50.4±1.1 *** growth and development of the infants was normal at birth,and no infants had birth defects related to TDF *** infants completed HBV vaccination and had no evidence of vertical ***:The use of TDF in pregnant females with chronic HBV and LAM or Ld T resistance was safe and effective.

关键词： Pregnancy Chronic hepatitis B Tenofovir Safety Bir

PROMOTING SILTATION EFFECTS AND IMPACTS OF HENGSHA EAST SHOAL ON THE YANGTZE RIVER ESTUARY

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2011年第5期23卷 649-659页

作者： XIE jun YAN yi-xin College of Harbor Coastal and Offshore Engineering Hohai University Nanjing 210098 China Shanghai Waterway Engineering Design and Consulting Co. Ltd Shanghai 200120 China

For the Hengsha East Shoal Promoting Siltation Project in the Yangtze River Estuary, this work developed a formula for calculating sediment carrying capacity based on variable coefficients and a mathematical model for suspended sedimentation using variable saturation recovery coefficients. Not only does the model yield good verification, preferably give the hydrodynamics and the sediment concentration, but also reach a good agreement between the simulation results andlux by tide for studying the effect the measured topographical changes in the promoting siltation zone of the Hengsha East Shoal. Moreover, this article proposes a method for examing the net sediment tran- sportation fs of the project of promoting siltation and comparatively analyzes the current siltation of the Hengsha East Shoal and siltation mouth layouts, entrance widths, entrance bottom elevations, and the impact of the South Main Dike on promoting siltation through calculating the net sediment transportation flux by tide over the fixed bed and the direct movable bed numerical simulations. The results are in good agreement with each other, indicating that the method for calculating the net sedi- ment transportation flux by the tide is also useful for assessing the project in promoting siltation. Finally, we use the modeling results to analyze the water and sediment diversion ratios and the changes in silting and scouting in riverbeds and draw the conclusion that the completion of the Hengsha East Shoal Promoting Siltation Project would not adversely affect the Yangtze River Estuary Deepwater Channel Project.

关键词： Hengsha East Shoal promoting siltation effects mathematical simulation sediment diversion ratio net sediment transportation flux

Generalized fairing algorithm of parametric cubic splines

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第9期7卷 1572-1577页

作者： WANG Yuan-jun cao Yuan School of Mathematical Science Fudan University Shanghai 200433 China

Kjellander has reported an algorithm for fairing uniform parametric cubic splines. Poliakoff extended Kjellander’s algorithm to non-uniform case. However, they merely changed the bad point’s position, and neglected the smoothing of tangent at bad point. In this paper, we present a fairing algorithm that both changed point’s position and its corresponding tangent vector. The new algorithm possesses the minimum property of energy. We also proved Poliakoff’s fairing algorithm is a deduction of our fairing algorithm. Several fairing examples are given in this paper.

关键词： Curve fairing Tangent vector Energy optimization Cubic splines

Predictive control of a direct internal reforming SOFC using a self recurrent wavelet network model

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第1期11卷 61-70页

作者： jun LI Nan GAO Guang-yi cao Heng-yong TU Ming-ruo HU Xin-jian ZHU Jian LI Institute of Fuel Cell Department of Automation Shanghai Jiao Tong University Shanghai 200240 China Department of Mathematics Shanghai University Shanghai 200444 China College of Materials Science and Engineering Huazhong University of Seience and Technology Wuhan 430074 China

In this paper,an application of a nonlinear predictive controller based on a self recurrent wavelet network (SRWN) model for a direct internal reforming solid oxide fuel cell (DIR-SOFC) is presented. As operating temperature and fuel utilization are two important parameters,the SOFC is identified using an SRWN with inlet fuel flow rate,inlet air flow rate and current as inputs,and temperature and fuel utilization as outputs. To improve the operating performance of the DIR-SOFC and guarantee proper operating conditions,the nonlinear predictive control is implemented using the off-line trained and on-line modified SRWN model,to manipulate the inlet flow rates to keep the temperature and the fuel utilization at desired levels. Simulation results show satisfactory predictive accuracy of the SRWN model,and demonstrate the excellence of the SRWN-based predictive controller for the DIR-SOFC.

关键词： Direct internal reforming (DIR) Solid oxide fuel cell (SOFC) Predictive control Self recurrent wavelet network (SRWN)

Analysis of load and adaptability of disc cutters during shield tunneling in soft-hard varied strata

在线全文

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2023年第4期17卷 533-545页

作者： Fengwei YANG Weilin SU yi YANG Zhiguo cao Yellow River Engineering Consulting Co. Ltd.Zhengzhou 450003China Key Laboratory of Water Management and Water Security for Yellow River Basin Ministry of Water ResourcesZhengzhou 450003China Key Laboratory of Urban Underground Engineering of Ministry of Education Beijing Jiaotong UniversityBeijing 100044China

The disc cutters of shield machines exhibit unsatisfactory adaptability and performance during the soft–hard varied strata tunneling *** analyze the rotation state,cutting performance,and adaptability of disc cutters during shield tunneling in soft–hard varied strata,the Holmquist Johnson Cook and Federal Highway Administration constitutive models are introduced to numerically simulate the failure process of materials on the excavation face and to calculate the load of disc ***,the parameters of the models are modified based on laboratory disc cutter excavation test *** results of numerical calculation can reflect the load level and the behavior of the disc cutters during *** tangential loads of the disc cutters during the cutting of four typical soft-strata excavation face models are numerically calculated,thus providing reference values for the starting torque of the disc cutters.A greater penetration is suggested for soft-strata tunneling to allow the disc cutters to rotate smoothly and continuously as well as to guarantee a better cutting *** disc cutters in the center of the cutterhead should be specified with a lower starting torque to prevent uneven wear,rotation stagnation,cutterhead clogging,and other adverse phenomena.

关键词： shield tunneling disc cutter load laboratory excavation test numerical calculation soft-hard varied strata

Numerical study of the influence of the atmospheric pressure on the thermal environment in the passenger cabin

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Building Simulation 2024年第2期17卷 253-265页

作者： Xin Su Yu Guo Zhengwei Long yi cao Tianjin Key Lab.of Indoor Air Environmental Quality Control School of Environmental Science and EngineeringTianjin UniversityTianjin300072China Shanghai Aircraft Design and Research Institute Jinke RoadPudong DistrictShanghai201210China

The cabin air pressure remains lower than the horizontal atmospheric pressure when the airplane is in *** pressure is one of the parameters that must be taken into consideration while studying the thermal environment of an airplane *** are still no reference values for aircraft cabins despite the fact that numerous studies on low pressure heat transfer have demonstrated the connection between convective heat transfer coefficient(CHTC)and air *** this paper,a correction method for CHTC under low pressure conditions was established by using the dummy heat dissipation in the low-pressure cabin *** this basis,a thermal environment simulation model was developed,then was applied to the simulation of a seven-row aircraft cabin containing 42 passengers,and the CHTC and heat loss of dummy surface in the cabin were ***,the results of PMV calculated by using heat dissipation and air parameters at sampling points were *** results show that the modified CHTC can accurately reflect the cabin thermal environment under low pressure conditions,and the correction of CHTC can be realized by adjusting the turbulent Prandtl number,which is nonlinear correlated with the *** simulation results of the thermal environment in the seven-row cabin show that the CHTC changes by about 42%before and after *** air pressure decreases during take-off,which reduces the average CHTC of the crew surface from 5.09 W/(m^(2)·K)to 4.56 W/(m^(2)·K),but the air temperature rises by about 0.2°C as a *** deviation of PMV results calculated by using simulated heat loss data and using air parameters of measuring points in space is up to 0.5,but the latter is representative for calculating the thermal comfort level of the whole cabin.

关键词： low pressure aircraft cabin simulation heat dissipation convective heat transfer coefficient