检索结果-南通市图书馆

Accurate prediction of biliary atresia with an integrated model using MMP-7 levels and bile acids

World Journal of Pediatrics 2024年第8期20卷 822-833页

作者： yi-jiang han Shu-Qi Hu Jin-hang Zhu Xiao Cai Deng-Ming Lai Bao-Hai Chen Kun Zhu Qiao Tong Xin-Rui Zhou Jia-Le Deng Jin-Fa Tou Zhuo Fang Li-Zhong Du Department of Neonatal Surgery Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhouChina Department of Data and Analytics WuXi Diagnostics Innovation Research InstituteShanghaiChina Department of Information Center Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhouChina Department of Pathology Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhouChina Department of Neonatology Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhouChina

Background Biliary atresia(BA)is a rare fatal liver disease in children,and the aim of this study was to develop a method to diagnose BA *** We determined serum levels of matrix metalloproteinase-7(MMP-7),the results of 13 liver tests,and the levels of 20 bile acids,and integrated computational models were constructed to diagnose *** Our findings demonstrated that MMP-7 expression levels,as well as the results of four liver tests and levels of ten bile acids,were significantly different between 86 BA and 59 non-BA patients(Phan liver test results and bile acid *** AUC was 0.890(95%CI 0.837,0.943)for liver test results and 0.825(95%CI 0.758,0.892)for bile acid ***,bile levels had a higher contribution to enhancing the predictive accuracy of MMP-7 levels(AUC=0.976,95%CI 0.953,1.000)than liver test *** AUC was 0.983(95%CI 0.962,1.000)for MMP-7 levels combined with liver test results and bile acid *** addition,we found that MMP-7 levels were highly correlated with gamma-glutamyl transferase levels and the liver fibrosis *** The innovative integrated models based on a large number of indicators provide a noninvasive and cost-effective approach for accurately diagnosing BA in children.

关键词： Bile aid.Biliary atresia Diagnosis Liver fibrosis Liver test MMP-7

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

尊重劳动者与保护投资者

引用

经济问题 2024年第4期 76-83页

作者：姜一涵吴秋生山西财经大学会计学院山西太原030006

尊重劳动者,提高企业劳动收入份额,是实现社会主义共同富裕的本质要求,它对保护投资者是否同样有利,关系到这项要求能否得到自觉持续响应。以2013年至2022年我国沪深A股上市公司为样本进行研究,发现企业尊重劳动者也有利于保护投资者,... 详细信息

尊重劳动者,提高企业劳动收入份额,是实现社会主义共同富裕的本质要求,它对保护投资者是否同样有利,关系到这项要求能否得到自觉持续响应。以2013年至2022年我国沪深A股上市公司为样本进行研究,发现企业尊重劳动者也有利于保护投资者,当企业所处地区教育发展水平和企业数字化发展水平较高时,这种效应更显著。经过一系列稳健性检验,结论依然成立。进一步研究发现,提高创新投入和缓解投资不足发挥部分中介作用,尊重劳动者与保护投资者的正向关系在国有企业、劳动密集型企业中更显著。研究结论为企业自觉响应国家号召,提高劳动收入份额、保护投资者权益、实现共同富裕提供了有益启示。

关键词：劳动收入份额投资者权益地区教育发展水平企业数字化发展水平

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

水葫芦生物炭联合高碘酸盐高效去除水中磺胺嘧啶

引用

中国环境科学 2024年第7期44卷 3767-3779页

作者：张悦袁玉龙晏彩霞姜一晗苏美淇丁明军王鹏聂明华江西师范大学地理与环境学院鄱阳湖湿地与流域研究教育部重点实验室流域生态智能监测与综合治理江西省重点实验室江西南昌330022

以入侵植物水葫芦为原料,制备了水葫芦生物炭(EBC),发现EBC能够高效活化高碘酸盐(PI),促进磺胺嘧啶(SD)的降解,且效能优于喜旱莲子草BC和加拿大一枝黄花BC.相较于其他热解温度,500℃条件下制备的EBC(EBC500)可更好地活化PI,在较低剂量的... 详细信息

以入侵植物水葫芦为原料,制备了水葫芦生物炭(EBC),发现EBC能够高效活化高碘酸盐(PI),促进磺胺嘧啶(SD)的降解,且效能优于喜旱莲子草BC和加拿大一枝黄花BC.相较于其他热解温度,500℃条件下制备的EBC(EBC500)可更好地活化PI,在较低剂量的PI(0.15mmol/L)条件下,20min内可将SD完全去除.随着EBC500和PI投加量的提升,SD的去除速率不断提高.猝灭实验和电子顺磁共振分析表明,碘自由基(⋅IO_(3),⋅IO_(4))、超氧自由基(O_(2)^(•−))、单线态氧(1 O_(2))是EBC500/PI体系降解SD的主要活性物种.同时,在EBC500和PI投加量分别为0.15g/L和0.15mmol/L的条件下,SD能够在较宽泛的初始pH值范围内(5~9)被完全去除.Cl^(−)、SO_(4)^(2−)和NO_(3)^(−)对SD的降解没有显著影响,但HCO_(3)^(−)和腐殖酸会抑制SD的去除.EBC500/PI体系可较好地应用于实际水体中SD的去除,对于其他典型磺胺类抗生素的降解也有良好的应用潜能,且EBC500具有良好的重复使用性.此外,根据6种中间产物,提出了SD的降解途径.通过生态毒性分析和植物种子萌发实验证明,EBC500/PI体系可显著降低SD溶液的生物毒性,说明该体系具有广阔的应用前景.

关键词：高级氧化技术高碘酸盐生物炭磺胺嘧啶降解

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-precision nondestructive evaluation of a thermal barrier coating based on perovskite quantum dot anion exchange

引用

Nano Research 2024年第5期17卷 4582-4592页

作者： Tao han Shufang Ding Zifan Wang Sirong jiang Pengjiang Jing Tianshang yi Yaqi Chen Chunzhi jiang Xiaofeng Zhang Microelectronics and Optoelectronics Technology Key Laboratory of Hunan Higher Education School of Physics and Electronic Electrical EngineeringXiangnan UniversityChenzhou 423000China National Engineering Laboratory for Modern Materials Surface Engineering Technology&The Key Lab of Guangdong for Modern Surface Engineering Technology Guangdong Institute of New MaterialsGuangdong Academy of SciencesGuangzhou 510650China

Thermal barrier coatings(TBCs)in gas turbine engines are used in expressly harsh environments;thus,assessing TBC integrity status is critical for safety and ***,traditional periodic maintenance involves visual inspections of the TBCs,requiring the gas turbine to be decommissioned and partially *** importantly,tiny defects or internal damages that easily cause coating failure cannot be *** this work,a new nondestructive evaluation(NDE)technique of TBCs based on quantum dot(QD)anion exchange is first explored *** exchanging anions between the Cl ions and the CsPbBr_(3) QDs,the degrees of salt corrosion of the TBCs are *** resultant NDE technique shows that the colour of the TBCs obviously changes from green to blue,accompanied by a large blueshift(~100 nm)of the photoluminescence(PL)peak *** addition,the relationship between the PL peak position and coating thermophysical properties indicates that the precision of this NDE technique may easily identify theμm-level of the thermal growth oxide(TGO)changes inside the TBCs.

关键词： thermal barrier coatings nondestructive evaluation CsPbBr_(3)quantum dot anion exchange thermal growth oxide

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hybrid Block Diagonalization Precoding for Multi-User Weighted Sum-Rate Maximization

引用

China Communications 2024年第8期21卷 127-141页

作者： Su Xiaofeng jiang yi Key Laboratory for Information Science of Electromagnetic Waves(MoE) Department of Communication Science and EngineeringFudan UniversityShanghai 200433China

This paper studies large-scale multi-input multi-output(MIMO)orthogonal frequency division multiplexing(OFDM)communications in a broadband frequency-selective channel,where a massive MIMO base station(BS)communicates with multiple users equipped with *** develop a hybrid precoding design to maximize the weighted sum-rate(WSR)of the users by optimizing the digital and the analog precoders *** the digital part,we employ block-diagonalization to eliminate inter-user interference and apply water-filling power allocation to maximize the *** the analog part,the optimization of the PSN is formulated as an unconstrained problem,which can be efficiently solved by a gradient descent *** results show that the proposed block-diagonal hybrid precoding algorithm can outperform the existing works.

关键词： block-diagonal gradient descent hybrid precoding iterative optimization MIMO-OFDM multi-user water-filling power allocation weighted sum-rate maximization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-Performance Anion Exchange Membrane Fuel Cells Enabled by Nitrogen Configuration Optimization in Graphene-Coated Nickel for Enhanced Hydrogen Oxidation

引用

Energy & Environmental Materials 2024年第5期7卷 345-352页

作者： Pan Li jiang Zhong Yanqing Fu Zhentao Du Lan jiang yi han Jan Luxa Bing Wu Zdenek Sofer Qiliang Wei Weiyou Yang School of Resources Environment and Materials State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Guangxi University Institute of Micro/Nano Materials and Devices Ningbo University of Technology Department of Inorganic Chemistry University of Chemistry and Technology Prague

Anion exchange membrane fuel cell （AEMFC） technology is attracting intensive attention,due to its great potential by using non-precious-metal catalysts （NPMCs） in the cathode and cheap bipolar plate materials in alkaline ***,in such case,the kinetics of hydrogen oxidation reaction （HOR） in the anode is two orders of magnitude sluggish than that of acidic electrolytes,which is recognized as the grand challenge in this ***,we report the rationally designed Ni nanoparticles encapsulated by N-doped graphene layers （Ni@NG） using a facile pyrolysis *** on the density functional theory calculations and electrochemical performance analysis,it is witnessed that the rich Pyridinic-N within the graphene shell optimizes the binding energy of the intermediates,thus enabling the fundamentally enhanced activity for HOR with robust *** a proof of concept,the resultant Ni@NG sample as the anode with a low loading(1.8 mg cm-2) in AEMFCs delivers a high peak power density of500 mW cm-2,outperforming all of those of NPMC-based analogs ever reported.

关键词： anion-exchange-membrane fuel cells density functional calculations hydrogen oxidation reaction Ni-based non-precious-metal catalysts pyridinic N-doped graphene

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

General formalism for dirty extreme-mass-ratio inspirals

引用

Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 22-29页

作者： Ye jiang Wen-Biao han Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China Shanghai Frontiers Science Center for Gravitational Wave Detection Shanghai 200240China

Detecting the environment around the supermassive black holes and tests of general relativity are important applications of extreme-mass-ratio inspirals(EMRIs).There is still a challenge to efficiently describe various“dirty”impacts on the inspirals,such as dark matter,gas,dipole radiation,and electromagnetic *** this study,we find the inherent linearity of the asymptotic solution of the inhomogeneous Teukolsky *** the basis of this property,we completely decouple the factors of the perturber and the background spacetime in the energy fluxes and *** the new decoupling form,the waveforms of EMRIs with non-geodesic motion in Kerr spacetime can be conveniently *** will help to resolve the environment(including gas,field,dark matter,electromagnetic interaction)around supermassive black holes and test general relativity.

关键词： gravitational wave Teukolsky equation extreme-mass-ratio inspirals

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evolution exploration and structure prediction of Keggin-type group IVB metal-oxo clusters

引用

Chinese Chemical Letters 2024年第5期35卷 487-492页

作者： Run-han Li Tian-yi Dang Wei Guan jiang Liu Ya-Qian Lan Zhong-Min Su School of Chemistry South China Normal UniversityGuangzhou 510006China Institute of Functional Material Chemistry Faculty of ChemistryNortheast Normal UniversityChangchun 130024China Institute of Theoretical Chemistry Jilin UniversityChangchun 130023China

The fascinating chemical structure and broad application prospect of Keggin-type polyoxometalates(POMs)have attracted many chemists to explore and discover *** the traditional Keggin,larger metal atomic radius,higher metal coordinated numbers,lower metal valence states and other features allow the group IVB metal-based Keggin(IVB-Keggin)more space and unknown in terms of structure and ***,density functional theory(DFT)calculations were performed to explore the influences including cores,shells,caps,and terminal ligands,et *** IVB-Keggin,and analyze the possibility of novel structure *** the perspective of multi-layer onion-like clusters,molecular energy level,host-guest interaction energy,surface charge and covalent bond polarity can be further adjusted to achieve the oriented design of functional *** insights are expected to provide theoretical support for experimental synthesis,opening a new perspective to understand the growth of Keggin.

关键词： Keggin Metal-oxo clusters Group IVB Onion pattern DFT

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-physics multi-scale simulation of unique equiaxed-to-columnar-to-equiaxed transition during the whole solidification process of Al-Li alloy laser welding

引用

Journal of Materials Science & Technology 2024年第4期171卷 235-251页

作者： Chu han Ping jiang Shaoning Geng Liangyuan Ren School of Mechanical Science and Engineering Huazhong University of Science&Technology(HUST)Wuhan430074China

In this study,a novel multi-physics multi-scale model with the dilute multicomponent phase-field method in three-dimensional(3D)space was developed to investigate the complex microstructure evolu-tion in the molten pool during laser welding of Al-Li *** accurately compute mass data within both two and three-dimensional computational domains,three efficient computing methods,including central processing unit parallel computing,adaptive mesh refinement,and moving-frame algorithm,were *** was placed on the distinctive equiaxed-to-columnar-to-equiaxed transition phenomenon that occurs during the entire solidification process of Al-Li alloy laser *** results indi-cated that the growth distance of columnar grains that epitaxially grew from the base metal(BM)de-creased as the nucleation rate *** the nucleation rate increased,the morphology of the newly formed grains near the fusion boundary(FB)changed from columnar to equiaxed,and newly formed equiaxed grains changed from having high-order dendrites to no obvious dendrite *** the nucleation rate was sufficiently high,non-dendritic equiaxed grains could directly form near the FB,and there was nearly no epitaxial growth from the ***,simulation results illustrated the com-petition among multiple grains with varying orientations that grow in 3D space near the ***,how equiaxed grain bands develop was *** equiaxed band not only hindered the growth of early columnar grains but also some of its grains could grow epitaxially to form new columnar *** predicted results were in good agreement with experimental measurements and observations.

关键词： Laser welding Al-Li alloy Equiaxed-to-columnar-to-equiaxed transition Multi-physics multi-scale model Multicomponent alloys 3D phase-field model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparative analysis of DNA-SIP and magnetic-nanoparticle mediated isolation (MMI) on unraveling dimethoate degraders

引用

Frontiers of Environmental Science & Engineering 2024年第1期18卷 59-69页

作者： Luning Lian yi Xing Dayi Zhang Longfei jiang Mengke Song Bo jiang School of Energy and Environmental Engineering University of Science&Technology BeijingBeijing 100083China Beijing Key Laboratory of Resource-oriented Treatment of Industrial Pollutants University of Science&Technology BeijingBeijing 100083China National Environmental and Energy Science and Technology International Cooperation Base University of Science&Technology BeijingBeijing 100083China College of New Energy and Environment Jilin UniversityChangchun 130021China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China College of Natural Resources and Environment South China Agricultural UniversityGuangzhou 510642China National Engineering Laboratory for Site Remediation Technologies Beijing 100015China

Microorganisms are crucial in the bioremediation of organophosphorus pesticides. However, most functional microorganisms (> 99%) are yet to be cultivated. This study applied two cultivation-independent approaches, DNA-SIP and magnetic-nanoparticle mediated isolation (MMI), to identify the functional microorganisms in degrading dimethoate in agricultural soils. MMI identified five dimethoate degraders: Pseudomonas, Bacillus, Ramlibacter, Arthrobacter, and Rhodococcus, whereas DNA-SIP identified three dimethoate degraders: Ramlibacter, Arthrobacter, and Rhodococcus. Also, MMI showed higher resolution than DNA-SIP in identifying functional microorganisms. Two organic phosphohydrolase (OPH) genes: ophC2 and ophB, were involved in dimethoate metabolism, as revealed by DNA-SIP and MMI. The degradation products of dimethoate include omethoate, O,O,S-trimethyl thiophosphorothioate, N-methyl-2-sulfanylacetamide, O,O-diethyl S-hydrogen phosphorodithioate, O,O,O-trimethyl thiophosphate, O,O,S-trimethyl thiophosphorodithioate, and O,O,O-trimethyl phosphoric. This study emphasizes the feasibility of using SIP and MMI to explore the functional dimethoate degraders, expanding our knowledge of microbial resources with cultivation-independent approaches.

关键词： Stable isotope probing(SIP) Magnetic-nanoparticle mediated isolation(MMI) Dimethoate Biodegradation Cultivation-independent approach

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：