检索结果-南通市图书馆

Clinical characteristics and prognosis of orbital solitary fibrous tumor in patients from a Chinese tertiary eye hospital

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第27期10卷 9670-9679页

作者： Ming-Yu Ren Jing Li yi-xiang wu Rui-Miao Li Chi Zhang Li-Min Liu Jing-Jing Wang Yu Gao Department of Orbital Disease and Ocular Tumor Hebei Eye HospitalXingtai 054001Hebei ProvinceChina Intensive Care Unit Xingtai Third HospitalXingtai 054001Hebei ProvinceChina Department of Medical Imaging Hebei Eye HospitalXingtai 054001Hebei ProvinceChina

BACKGROUND Solitary fibrous tumor(SFT) is predominant within the pleura but very rare in the orbit,which is why the diagnosis of orbital SFT poses challenges in clinical ***,an integrated approach that incorporates specific clinical features,histological,histopathological,and immunohistochemical(IHC) examinations,and molecular analyses is *** To retrospectively explore the clinical and imaging characteristics,treatment,outcomes of a series of patients with orbital *** We conducted a retrospective review of a series of patients diagnosed with a histopathologic orbital SFT treated at a single *** data on demographics,clinical characteristics,imaging,treatment,postoperative histopathological and IHC examinations,and prognosis were *** In total,13 patients were enrolled,7(53.8%) of whom had the tumor located in the superomedial quadrant of the *** tomography revealed a solitary ovoid lesion in 10(76.9%) patients and irregular lesion in 3(23.1%) *** resonance imaging results were as follows:On T1 weighted images,3(23.1%) patients had hypointense mixed signals,whereas 10(76.9%) patients showed isointense mixed signals;on T2 weighted images(T2 WI),3(23.1%),4 (30.8%),and 6(46.2%) patients exhibited hypointense mixed,isointense mixed,and hyperintense signals,***,12(92.3%) patients showed significant enhancement,whereas there were patchy slightly enhanced areas in the *** patients were treated by *** analysis demonstrated that the tumor cells were immunoreactive for CD34,CD99,STAT-6,and vimentin in all *** lesions showed Ki-67 positivity 10% in 2(15.4%).Two(15.4%) patients exhibited tumor *** The clinical manifestations and radiologic characteristics of orbital SFT are diverse and not *** diagnosis and treatment require detailed radiological and histopathological/IHC evalu

关键词： Orbit Solitary fibrous tumor Diagnostic imaging Immunohistochemistry Surgical therapy

Three-dimensional visualization technology for guiding one-step percutaneous transhepatic cholangioscopic lithotripsy for the treatment of complex hepatolithiasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第28期30卷 3393-3402页

作者： Yong-Qing Ye Ya-Wen Cao Rong-Qi Li En-Ze Li Lei Yan Zhao-Wei Ding Jin-Ming Fan Ping Wang yi-xiang wu Department of Hepatobiliary Surgery The Second People’s Hospital of FoshanFoshan 528000Guangdong ProvinceChina Department of Emergency Medicine Biomedical Innovation CenterThe Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou 510655Guangdong ProvinceChina Department of Hepatobiliary Surgery Foshan Hospital of Traditional Chinese MedicineFoshan 528000Guangdong ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510282Guangdong ProvinceChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization *** with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)*** This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for *** patients were divided into two groups:The 3D-PTOBF group and the PTOBF *** clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were *** Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)*** immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF *** complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF *** Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary *** perioperative and long-term outcomes are satisfactory for patients with complicated primary *** minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery.

关键词： Hepatolithiasis One-step percutaneous transhepatic cholangioscopic lithotripsy Biliary disease Three-dimensional visualization Clinical efficacy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

《大学体育》精品课程建设的实践与思考

体育学刊 2008年第8期15卷 49-52页

作者：刘忆湘阳艺武武汉理工大学体育部湖北武汉430070

通过对《大学体育》精品课程建设现状的调查分析,结合课程建设的实践,提出建设《大学体育》精品课程要结合实际突出课程特色、体现大学体育的育人功能、建立切实有效的课程评价机制、充分发挥网络的作用、促进校园文化建设等方面来加强... 详细信息

通过对《大学体育》精品课程建设现状的调查分析,结合课程建设的实践,提出建设《大学体育》精品课程要结合实际突出课程特色、体现大学体育的育人功能、建立切实有效的课程评价机制、充分发挥网络的作用、促进校园文化建设等方面来加强。将《大学体育》课程建设成目标明确、框架清晰、课程内容特色鲜明、教学方法与手段新颖且切合实际的示范性课程。

关键词：大学体育精品课程课程建设

在线全文

学校读者我要写书评

暂无评论

神经网络在预测编码中的应用

系统工程与电子技术 2002年第12期24卷 88-91页

作者：吴贻鼎朱翔吴谋硕武汉大学电子信息学院湖北武汉430072

讨论如何有效地利用backpropagation(BP)神经网络进行预测编码。改进的BP算法可以提高BP神经网络地收敛速度、泛化能力和稳定性。一般而言 ,四层网络比三层网络具有更快地学习速度 ;二阶网络比一阶网络性能更优越。利用MATLAB程序 ,构... 详细信息

讨论如何有效地利用backpropagation(BP)神经网络进行预测编码。改进的BP算法可以提高BP神经网络地收敛速度、泛化能力和稳定性。一般而言 ,四层网络比三层网络具有更快地学习速度 ;二阶网络比一阶网络性能更优越。利用MATLAB程序 ,构造三层、四层和二阶BP神经网络进行预测编码。测试结果表明 ,利用规模足够大的三层BP网络进行预测编码可以取得较好效果 ;

关键词：神经网络图像压缩预测编码 Matlab程

在线全文

学校读者我要写书评

暂无评论

绿色发展的国际先进经验及其对中国的启示

新疆师范大学学报（哲学社会科学版） 2017年第2期38卷 18-24页

作者：杨宜勇吴香雪杨泽坤国家发改委宏观经济研究院社会发展研究所北京100038 中国人民大学公共管理学院北京100872 德国不来梅雅各布大学汉堡28759

随着经济的不断发展,经济增长与资源环境之间的张力越来越大,给中国经济社会的可持续发展带来沉重压力。中共十八届五中全会提出"五大发展理念",将绿色发展提高到突出位置,强调走绿色发展之路,以实现经济社会发展与资源环境的共生共荣... 详细信息

随着经济的不断发展,经济增长与资源环境之间的张力越来越大,给中国经济社会的可持续发展带来沉重压力。中共十八届五中全会提出"五大发展理念",将绿色发展提高到突出位置,强调走绿色发展之路,以实现经济社会发展与资源环境的共生共荣。国外发达国家已有成功的绿色发展经验,值得合理借鉴。走绿色发展之路要立法先行,严格监管,综合利用各种绿色发展的政策工具,统筹绿色发展规划与重点治理相结合,强化企业的作用,不断创新绿色发展技术,要求社会公众积极参与,并加强环境教育,提高全社会环境保护的意识。

关键词：绿色发展国际经验绿色经济生态文明

Repetitive transcranial magnetic stimulation in Alzheimer’s disease:effects on neural and synaptic rehabilitation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 326-342页

作者： yi Ji Chaoyi Yang Xuerui Pang yibing Yan Yue wu Zhi Geng Wenjie Hu Panpan Hu Xingqi wu Kai Wang Department of Neurology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders HefeiAnhui ProvinceChina Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health HefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina Department of Psychology and Sleep Medicine The Second Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina

Alzheimer’s disease is a neurodegenerative disease resulting from deficits in synaptic transmission and *** Alzheimer’s disease brain tends to be hyperexcitable and hypersynchronized,thereby causing neurodegeneration and ultimately disrupting the operational abilities in daily life,leaving patients *** transcranial magnetic stimulation is a cost-effective,neuro-modulatory technique used for multiple neurological *** the past two decades,it has been widely used to predict cognitive decline;identify pathophysiological markers;promote neuroplasticity;and assess brain excitability,plasticity,and *** has also been applied to patients with dementia,because it can yield facilitatory effects on cognition and promote brain recovery after a neurological ***,its therapeutic effectiveness at the molecular and synaptic levels has not been elucidated because of a limited number of *** study aimed to characterize the neurobiological changes following repetitive transcranial magnetic stimulation treatment,evaluate its effects on synaptic plasticity,and identify the associated *** review essentially focuses on changes in the pathology,amyloidogenesis,and clearance pathways,given that amyloid deposition is a major hypothesis in the pathogenesis of Alzheimer’s *** mechanisms associated with repetitive transcranial magnetic stimulation procedures and different pathways mediating gene transcription,which are closely related to the neural regeneration process,are also ***,we discuss the outcomes of animal studies in which neuroplasticity is modulated and assessed at the structural and functional levels by using repetitive transcranial magnetic stimulation,with the aim to highlight future directions for better clinical translations.

关键词： Alzheimer’s disease amyloid deposition apoptotic mechanisms biomarker neural regeneration neurodegeneration repetitive transcranial magnetic stimulation synaptic plasticity

水泥厂设备管理多层分布系统及优化设计的实现

在线全文

学校读者我要写书评

暂无评论

四川大学学报（自然科学版） 2003年第2期40卷 251-255页

作者：夏翔范轶翔吴庆星胡纫兰四川大学物理科学与技术学院成都610064

作者研究了水泥厂设备管理多层分布系统结构的设计及其良好扩展性的实现 ,重点针对一般MIS系统忽视效益的弊病 ,建立了一种设备优化管理的平台 ,该平台可使企业提高管理效益 .

关键词：设备管理系统多层分布结构设备优化管理最短路径水泥厂系统设计

Role of triggering receptor expressed on myeloid cells 1/2 in secondary injury after cerebral hemorrhage

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第9期13卷 1-12页

作者： Fan yi Hao wu Hai-Kang Zhao Xi’an Medical University Xi’an 710021Shaanxi ProvinceChina Department of Neurosurgery The Second Affiliated Hospital of Xi’an Medical UniversityXi’an 710038Shaanxi ProvinceChina

Intracerebral hemorrhage(ICH)is a common severe emergency in neurosurgery,causing tremendous economic pressure on families and society and devastating effects on patients both physically and psychologically,especially among patients with poor functional *** is often accompanied by decreased consciousness and limb *** seriously affects patients’ability to live *** rapid advances in neurosurgery have greatly improved patient survival,there remains insufficient evidence that surgical treatment significantly improves long-term *** in-depth pathophysiological studies after ICH,increasing evidence has shown that secondary injury after ICH is related to long-term prognosis and that the key to secondary injury is various immune-mediated neuroinflammatory reactions after *** basic and clinical studies of various systemic inflammatory diseases,triggering receptor expressed on myeloid cells 1/2(TREM-1/2),and the TREM receptor family is closely related to the inflammatory *** inflammatory diseases can be upregulated and downregulated through receptor *** the TREM receptor functions after ICH,the types of results from intervention,and whether the outcomes can improve secondary brain injury and the long-term prognosis of patients are *** analysis of relevant research results from basic and clinical trials revealed that the inhibition of TREM-1 and the activation of TREM-2 can alleviate the neuroinflammatory immune response,significantly improve the long-term prognosis of neurological function in patients with cerebral hemorrhage,and thus improve the ability of patients to live independently.

关键词： Cerebral hemorrhage Secondary injury Triggering receptor expressed on myeloid cells 1/2 Neurosurgery Inflammatory response

Single-cell transcriptomic profiling reveals ZEB1-mediated regulation in microglial subtypes and the impact of exercise on neuroinflammatory responses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Traditional Medicine Research 2025年第2期10卷 55-64页

作者： Jin-Fang wu yi-Sheng Chen Yu-Chun Xie Department of Rehabilitation Medicine Jiangsu Province Geriatric HospitalNanjing 210024China Fujian Key Laboratory of Toxicant and Drug Toxicology Medical CollegeNingde Normal UniversityNingde 352100China Central Laboratory Jiangsu Province Geriatric HospitalNanjing 210024China

Background:This study aims to identify distinct cellular subtypes within brain tissue using single-cell transcriptomic analysis,focusing on specific biomarkers that differentiate cell types and the effects of traditional and exercise ***:Four samples were analyzed:older control(OC),older exercise(OE),younger control(YC),and younger exercise(YE).Single-cell RNA sequencing was used to distinguish cellular subtypes through their biomarker *** visualization included violin and t-SNE plots to illustrate biomarker expression across cell clusters such as oligodendrocytes,microglia,and ***,BV2 cells were exposed to amyloid-beta fragments to simulate Alzheimer’s disease,assessing the impact of exercise-induced cellular ***:Distinct cellular subtypes were identified:oligodendrocytes(MBP,St18),microglia(Dock8),and astrocytes(Aqp4,Gpc5).Sample OE was predominantly oligodendrocytes,while YE had more astrocytes,inhibitory neurons,and Canal-Retzius *** showed a significant presence of Olfm3+ganglion ***1 gene knockout revealed changes in SMAD family gene expression,which regulate *** stress levels were also ***:This profiling enhances our understanding of brain cellular functions and interactions,potentially informing targeted therapies in neurological *** may influence brain cell immune responses and cell death pathways by regulating specific gene expressions,offering new insights for treating neuroinflammation and degeneration.

关键词： single-cell transcriptomics brain tissue cellular subtypes biomarker expression neuronal diversity