检索结果-南通市图书馆

Nanotechnology’s frontier in combatting infectious and inflammatory diseases:prevention and treatment

Signal Transduction and Targeted Therapy 2024年第3期9卷 998-1047页

作者： Yujing Huang Xiaohan Guo yi wu Xingyu Chen Lixiang Feng Na Xie Guobo Shen Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China Hospitaland West China School of Basic Medical Sciences and Forensic MedicineSichuan Universityand Collaborative Innovation Center for BiotherapyChengdu 610041China

Inflammation-associated diseases encompass a range of infectious diseases and non-infectious inflammatory diseases,which continuously pose one of the most serious threats to human health,attributed to factors such as the emergence of new pathogens,increasing drug resistance,changes in living environments and lifestyles,and the aging *** rapid advancements in mechanistic research and drug development for these diseases,current treatments often have limited efficacy and notable side effects,necessitating the development of more effective and targeted anti-inflammatory *** recent years,the rapid development of nanotechnology has provided crucial technological support for the prevention,treatment,and detection of inflammation-associated *** types of nanoparticles(NPs)play significant roles,serving as vaccine vehicles to enhance immunogenicity and as drug carriers to improve targeting and *** can also directly combat pathogens and *** addition,nanotechnology has facilitated the development of biosensors for pathogen detection and imaging techniques for inflammatory *** review categorizes and characterizes different types of NPs,summarizes their applications in the prevention,treatment,and detection of infectious and inflammatory *** also discusses the challenges associated with clinical translation in this field and explores the latest developments and *** conclusion,nanotechnology opens up new possibilities for the comprehensive management of infectious and inflammatory diseases.

关键词： prevention inflammatory treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Combined Antenna Array Deployment with High Positioning Accuracy and Low Angular Measurement Error

引用

Journal of Beijing Institute of Technology 2024年第2期33卷 141-154页

作者： Wangjie Chen Weiqiang Zhu Zhenhong Fan Li wu yi He yixiao Wang School of Electronic and Optical Engineering Nanjing University of Science and TechnologyNanjing 210094China Nanjing Electronis Equipment Institute Nanjing 210000China

In this paper,an antenna array composed of circular array and orthogonal linear array is proposed by using the design of long and short baseline“orthogonal linear array”and the circular array ambiguity resolution design of multi-group baseline *** effectiveness of the antenna array in this paper is verified by sufficient simulation and *** the system deviation correction work,it is found that in the L/S/C/X frequency bands,the ambiguity resolution probability is high,and the phase difference system error between each channel is basically the *** angle measurement error is less than 0.5°,and the positioning error is less than 2.5 ***,as the center frequency increases,calibration consistency improves,and the calibration frequency points become applicable over a wider frequency *** a center frequency of 11.5 GHz,the calibration frequency point bandwidth extends to 1200 *** combined antenna array deployment holds significant promise for a wide range of applications in contemporary wireless communication systems.

关键词： antenna array deployment ambiguity resolution phase consistency angle measurement error positioning error

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chemokine platelet factor 4 accelerates peripheral nerve regeneration by regulating Schwann cell activation and axon elongation

引用

Neural Regeneration Research 2024年第1期19卷 190-195页

作者： Miao Gu Xiao Cheng Di Zhang Weiyan wu yi Cao Jianghong He Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education Co-innovation Center of NeuroregenerationNMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology ProductsNantong UniversityNantongJiangsu ProvinceChina School of Basic Medical Sciences Hebei Key Laboratory of Nerve Injury and RepairChengde Medical UniversityChengdeHebei ProvinceChina

Schwann cells in peripheral nerves react to traumatic nerve injury by attempting to grow and *** r,it is unclear what factors play a role in this *** this study,we searched a GEO database and found that expression of platelet factor 4 was markedly up-regulated after sciatic nerve *** factor is an important molecule in cell apoptosis,diffe rentiation,survival,and ***,polymerase chain reaction and immunohistochemical staining confirmed the change in platelet factor 4 in the sciatic nerve at different time points after ***-linked immunosorbent assay confirmed that platelet factor 4 was secreted by Schwann *** also found that silencing platelet factor 4 decreased the proliferation and migration of primary cultured Schwann cells,while exogenously applied platelet factor 4 stimulated Schwann cell prolife ration and migration and neuronal axon ***,knocking out platelet factor 4 inhibited the prolife ration of Schwann cells in injured rat sciatic *** findings suggest that Schwann cell-secreted platelet factor 4 may facilitate peripheral nerve repair and regeneration by regulating Schwann cell activation and axon ***,platelet factor 4 may be a potential therapeutic target for traumatic peripheral nerve injury.

关键词： axon elongation bioinformatic analysis cell migration cell proliferation dorsal root ganglia peripheral nerve regeneration peripheral nerve trauma platelet factor 4 rat sciatic nerve Schwann cells

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bidirectional energy-controlled piezoelectric shunt damping technology and its vibration attenuation performance

引用

International Journal of Mechanical System Dynamics 2024年第1期4卷 63-76页

作者： yipeng wu quan Yuan Kaibin Ren Xin Shen Hui Shen Adrien Badel Hongli Ji Jinhao Qiu State Key Laboratory of Mechanics and Control for Aerospace Structures Nanjing University of Aeronautics and AstronauticsNanjingChina College of Mechanical and Electrical Engineering Qingdao UniversityQingdaoChina SYMME Laboratory Universite Savoie Mont BlancAnnecy le VieuxFrance

Piezoelectric material-based semi-active vibration control systems may effectively suppress vibration amplitude without any external power supply,or even harvest electrical *** bidirectional electrical energy control phenomenon is theoretically introduced and validated in this paper.A flyback transformer-based switching piezoelectric shunt circuit that can extract energy from or inject energy into piezoelectric elements is *** analytical expressions of the controlled energy and the corresponding vibration attenuation are therefore derived for a classical electromechanical cantilever *** predictions validated by the experimental results show that the structure vibration attenuation can be tuned from−5 to−25 dB under the given electrical quality factor of the circuit and figure of merit of the electromechanical structure,and the consumed power is in the range of−13 to 25 mW,which is a good theoretical basis for the development of self-sensing,self-adapting,and self-powered piezoelectric vibration control systems.

关键词： vibration control piezoelectric shunt damping electromechanical energy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Two-dimensional semiconductor heterostructures for photocatalytic COconversion

引用

Science China Chemistry 2024年

作者： Yang wu Mingyu wu Yongfu Sun yi Xie University of Science and Technology of China Hefei National Research Center for Physical Sciences at Microscale

The CO2reduction into carbon-contained fuel via solar energy offers the powerful tools to realize the zero-emission carbon cycle. Owing to the intriguing features of the two-dimensional(2D) heterostructures, it is susceptible to modulate the electronic structure as well as the surface geometry for optimizing the photocatalytic CO2reactivity. From this perspective, we surveyed the fundamental insights of 2D semiconductor heterostructures, involving the fabrication strategies and classification of the 2D semiconductor heterostructure. Also, we have detailly discussed the overview of 2D semiconductor heterostructure for optimizing CO2photocatalytic influenced factors, including the solar energy utilization, photogenerated carriers separation, and redox reaction kinetics. Afterwards, we showed the significant advantages of 2D heterostructures in elevating CO2photoreduction performance, focusing on activity, selectivity and photostability. By analyzing the limitations and developments, we ended by putting forward insights into the further researches about the CO2photocatalysts and reactor design, even industrial applications.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

New Food Sources and Production Systems: A Comparison of International Regulations and China’s Advancements in Novel Foods with Synthetic Biology

引用

Food Science and Human Wellness 2024年

作者： Xin Liu Di wu yi Shao Yongning wu Key Laboratory for Deep Processing of Major Grain and Oil (The Chinese Ministry of Education) College of Food Science and Engineering wuhan Polytechnic University Institute for Global Food Security School of Biological Sciences Queen's University Belfast Department of Nutrition and Food Safety Peking Union Medical College Research Unit of Food Safety Chinese Academy of Medical Sciences NHC Key Laboratory of Food Safety Risk Assessment China National Center for Food Safety Risk Assessment

The global shift towards sustainable food systems has sparked innovations in food sources and production systems， including cell-based meat， plant-based food products， precision fermentation， and 3D food printing. These advancements pose regulatory challenges and opportunities， with China emerging as a critical player in adopting and regulating new food technologies. This review explores the international landscape of new food sources and production systems， focusing on China’s role and regulatory approaches compared to global practices. Through this comparative analysis， we aim to contribute to the ongoing dialogue on food safety regulation， offering insights and recommendations for policymakers， industry stakeholders， and researchers engaged in the global food system’s evolution. This comprehensive overview underscores the dynamic nature of regulatory frameworks governing NFPS， highlighting the international efforts to ensure food safety， consumer protection， and the sustainable evolution of the food industry.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Porous Ti_(3)C_(2)T_(x) MXene nanosheets sandwiched between polyimide fiber mats for electromagnetic interference shielding

引用

Nano Research 2024年第3期17卷 2070-2078页

作者： Wenhao Liang Juntao wu Shan Zhang Pei-Yan Zhao yi Cong Yongqiang Guo Guang-Sheng Wang Key Laboratory of Bioinspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191China

With the rapid development of wireless communication technology and electronic devices,the issue of electromagnetic interference(EMI)is becoming increasingly *** a new and flexible electromagnetic interference shielding material has become a challenging ***,a sandwich-structured EMI shielding composite film was prepared using electrospinning and vacuum filtration *** this process,a porous MXene was synthesized through a reaction with cobalt acetate and served as the intermediate layer in the composite film to shield electromagnetic *** electrospun polyimide(PI)fibers were used as the top and bottom layers of the composite film,which can protect the porous MXene from *** lightweight and flexible composite film integrates electromagnetic interference shielding and thermal insulation capabilities,showing excellent comprehensive *** composite film achieves an EMI shielding effectiveness of 48.8 dB in X-band(8.2–12.4 GHz),and absolute shielding effectiveness of the composite film reached a satisfying 4142.43(dB·cm^(2))/*** to the design of a multi-layer porous structure,the density of the composite film is 0.65 g/***,the thermal conductivity of the film is 0.042 W/(m·K)due to the clamping of electrospun PI fibers,showing excellent thermal insulation ***,the composite film exhibits excellent high and low-temperature *** summary,this work provides a feasible strategy for preparing a lightweight polymer-based EMI shielding film.

关键词： porous MXene polyimide electromagnetic interference shielding thermal insulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Crystal phase control and ignition properties of HNS/CL-20 composite microspheres prepared by microfluidics combined with emulsification techniques

引用

Particuology 2024年第2期85卷 241-251页

作者： yi Liu Yunyan Guo Rui Zhu Jinqiang Zhou Zhengxu Lin Kai Han Chongwei An Jingyu Wang Bidong wu School of Environment and Safety Engineering North University of ChinaTaiyuan030051China School of Engineering Beijing Institute of TechnologyBeijing100081China Shanxi Province Ultrafine Powder Engineering Technology Research Center Taiyuan030051China

Improved controllability and energy density of ignition agents are of great significance for the devel-opment of energetic composite *** this study,droplet microfluidics and emulsification tech-niques were combined to prepare HNS/CL-20 composite microspheres with polyglycidyl azide polymer(GAP)as the *** influence of binder content on the morphology of microspheres was investi-gated,and the microspheres were characterized and tested for particle size,crystal structure,thermal decomposition,dispersibility,mechanical sensitivity,combustion behavior and detonation *** results showed that microspheres prepared with a binder content of 3%had higher sphericity and particle size *** microspheres retained the crystal structure of both HNS and CL-20(ε-type).Compared with raw HNS,the microspheres had higher apparent activation energy,better safety per-formance,and good *** ignition experiments and detonation performance tests show that HNS/CL-20 composite microspheres have excellent ignition performance,obvious combustion flame,and significant energy release effects,which are expected to achieve high energy and high-speed response of the igniter,thus improving the ignition reliability in special environments or systems.

关键词： Droplet microfluidics Emulsification technology Energetic materials Composite microspheres Crystal phase control Ignition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Differential bonding behaviors of sodium/potassium-ion storage in sawdust waste carbon derivatives

引用

Chinese Chemical Letters 2024年第4期35卷 496-501页

作者： Jun-Ming Cao Kai-Yang Zhang Jia-Lin Yang Zhen-yi Gu Xing-Long wu MOE Key Laboratory for UV Light-Emitting Materials and Technology Northeast Normal UniversityChangchun 130024China Department of Chemistry Northeast Normal UniversityChangchun 130024China

Sodium-ion batteries(SIBs) and potassium-ion batteries(PIBs) are the most promising alternatives to lithium-ion batteries, and thus have drawn intensive research attention. Porous carbon materials from different precursors have been widely used as anode materials owing to their compatible storage effectiveness of both larger radii sodium and potassium ions. However, the differential bonding behaviors of Na and K ions with porous carbon-based anode are the significant one worth investigating, which could provide a clean picture of alkali ions storage mechanism. Therefore, in this work, we prepare a porous carbon network derived from sawdust(SDC) wastes, to further analyze the differences on sodium and potassium ions storage behaviors in terms of bond-forming process. It is found that, as-prepared SDC anodes could deliver stable sodium and potassium storage capacities, however, there are notable distinctions in terms of electrochemical behaviors and diffusion processes. By virtue of ex-situ XRD and Raman spectroscopy, the phase transition reaction of potassium ions could be well-observed, and the results shows that the multiple intercalated compounds was formed in SDC network during ions insertion, further resulting in slower diffusion kinetics and larger resistance compared to non-bonded process of sodium ions storage. This study provides more insights into the differences between sodium and potassium ions storage, as well as the energy storage mechanism of porous carbon as anodes for secondary batteries.

关键词： Porous carbon Sodium-ion storage Potassium-ion storage Bonding behaviors Batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development

引用

Journal of Molecular Cell Biology 2024年第1期16卷 43-53页

作者： Xiaozhen Song Ruixing Hu yi Chen Man Xiao Hong Zhang Shengnan wu Qing Lu Molecular Diagnostic Laboratory Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200040China Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education)Shanghai Jiao Tong UniversityShanghai 200030China Laboratory of Development and Diseases and State Key Laboratory for Medical Genomics Shanghai Institute of HematologyRuĳin HospitalShanghai JiaoTong University School of MedicineShanghai 200025China

TRAF7 serves as a crucial intracellular adaptor and E3 ubiquitin ligase involved in signal transduction pathways,contributing to immune responses,tumor progression,and embryonic *** mutations within the coiled-coil(CC)domain and WD40 repeat domain of TRAF7 could cause brain tumors,while germline pathogenic mutations contribute to severe developmental ***,the precise molecular mechanism underlying TRAF7 involvement in embryonic development remains *** this study,we employed zebrafish as an in vivo model ***7 knock down caused defects in zebrafish embryonic *** determined the crystal structure of TRAF7 CC domain at 3.3Åresolution and found that the CC region trimerization was essential for TRAF7 functionality during zebrafish embryonic ***,disease-causing mutations in TRAF7 CC region could impair the trimer formation,consequently impacting early embryonic development of ***,our study sheds light on the molecular mechanism of TRAF7 CC trimer formation and its pivotal role in embryonic development.

关键词： TRAF7 coiled-coil domain crystal structure trimerization embryonic development

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：